| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B G Schimmelmann, S Friedel, A Dempfle, A Warnke, K P Lesch, S Walitza, T J Renner, M Romanos, B Herpertz-Dahlmann, M Linder, H Schäfer, C Seitz, H Palmason, C Freitag, J Meyer, K Konrad, A Hinney, J Hebebran. No evidence for preferential transmission of common valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor gene (BDNF) in ADHD. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 4. 2007-10-04. PMID:17219016. |
we did not find support for an involvement of the val66 allele of the val66met polymorphism of bdnf in the pathogenesis of adhd in our sample. |
2007-10-04 |
2023-08-12 |
Not clear |
| J Lasky-Su, Stephen V Faraone, C Lange, M T Tsuang, A E Doyle, J W Smoller, N M Laird, J Biederma. A study of how socioeconomic status moderates the relationship between SNPs encompassing BDNF and ADHD symptom counts in ADHD families. Behavior genetics. vol 37. issue 3. 2007-09-18. PMID:17216343. |
a study of how socioeconomic status moderates the relationship between snps encompassing bdnf and adhd symptom counts in adhd families. |
2007-09-18 |
2023-08-12 |
Not clear |
| J Lasky-Su, Stephen V Faraone, C Lange, M T Tsuang, A E Doyle, J W Smoller, N M Laird, J Biederma. A study of how socioeconomic status moderates the relationship between SNPs encompassing BDNF and ADHD symptom counts in ADHD families. Behavior genetics. vol 37. issue 3. 2007-09-18. PMID:17216343. |
in this paper, we evaluated the possible role of bdnf as a moderator of attention deficit hyperactivity disorder (adhd) in the context of different socioeconomic classes. |
2007-09-18 |
2023-08-12 |
Not clear |
| J Lasky-Su, Stephen V Faraone, C Lange, M T Tsuang, A E Doyle, J W Smoller, N M Laird, J Biederma. A study of how socioeconomic status moderates the relationship between SNPs encompassing BDNF and ADHD symptom counts in ADHD families. Behavior genetics. vol 37. issue 3. 2007-09-18. PMID:17216343. |
this study suggests that different ses classes may modify the effect of the functional variant(s) in and around bdnf to have an impact on the number of adhd symptom counts that are observed. |
2007-09-18 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. Attention-deficit hyperactivity disorder may be associated with decreased central brain-derived neurotrophic factor activity: clinical and therapeutic implications. Medical hypotheses. vol 68. issue 4. 2007-07-18. PMID:16919891. |
recently, it has been proposed that brain-derived neurotrophic factor (bdnf), a member of the neurotrophic factor family, may be implicated in the pathogenesis of adhd. |
2007-07-18 |
2023-08-12 |
mouse |
| Shih-Jen Tsa. Attention-deficit hyperactivity disorder may be associated with decreased central brain-derived neurotrophic factor activity: clinical and therapeutic implications. Medical hypotheses. vol 68. issue 4. 2007-07-18. PMID:16919891. |
drawing on findings from studies into the drugs for adhd relating to central bdnf expression, hyperactivity in bdnf knockout mice, bdnf effects in midbrain dopaminergic function and the close association between bdnf and the dopamine transporter (an important molecule for adhd pathogenesis), it is proposed here that decreased central bdnf, particularly in the midbrain region, may play an important role in the pathogenesis adhd. |
2007-07-18 |
2023-08-12 |
mouse |
| Shih-Jen Tsa. Semax, an analogue of adrenocorticotropin (4-10), is a potential agent for the treatment of attention-deficit hyperactivity disorder and Rett syndrome. Medical hypotheses. vol 68. issue 5. 2007-06-06. PMID:16996699. |
since adhd is likely to be a neurodevelopmental disorder with disturbance in dopamine and bdnf function, it is proposed in this paper that semax may have good therapeutic potential in adhd. |
2007-06-06 |
2023-08-12 |
Not clear |
| Agnieszka Słopień, Monika Dmitrzak-Weglarz, Filip Rybakowski, Andrzej Rajewski, Joanna Hause. [Genetic background of ADHD: genes of the serotonergic system, other candidate genes, endophenotype]. Psychiatria polska. vol 40. issue 1. 2007-03-20. PMID:16756026. |
other possible factors in adhd background are substance influence on brain maturation, including n-methyl-d aspartate glutamate receptor 2a gene polymorphism (grin2a) and brain derived neurotrophic factor (bdnf) gene. |
2007-03-20 |
2023-08-12 |
Not clear |
| Xiaohui Xu, Jonathan Mill, Kaixin Zhou, Keeley Brookes, Chih-Ken Chen, Philip Asherso. Family-based association study between brain-derived neurotrophic factor gene polymorphisms and attention deficit hyperactivity disorder in UK and Taiwanese samples. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 1. 2007-02-27. PMID:17044097. |
several lines of evidence implicate the involvement of bdnf in attention-deficit hyperactivity disorder (adhd). |
2007-02-27 |
2023-08-12 |
Not clear |
| Xiaohui Xu, Jonathan Mill, Kaixin Zhou, Keeley Brookes, Chih-Ken Chen, Philip Asherso. Family-based association study between brain-derived neurotrophic factor gene polymorphisms and attention deficit hyperactivity disorder in UK and Taiwanese samples. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 1. 2007-02-27. PMID:17044097. |
this study investigated the role of two common bdnf variants (val66met, c270t) in two samples of adhd probands from the united kingdom (n = 180) and taiwan (n = 212). |
2007-02-27 |
2023-08-12 |
Not clear |
| Xiaohui Xu, Jonathan Mill, Kaixin Zhou, Keeley Brookes, Chih-Ken Chen, Philip Asherso. Family-based association study between brain-derived neurotrophic factor gene polymorphisms and attention deficit hyperactivity disorder in UK and Taiwanese samples. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 1. 2007-02-27. PMID:17044097. |
this study provides evidence for the possible involvement of bdnf in susceptibility to adhd. |
2007-02-27 |
2023-08-12 |
Not clear |
| L Kent, E Green, Z Hawi, A Kirley, F Dudbridge, N Lowe, R Raybould, K Langley, N Bray, M Fitzgerald, M J Owen, M C O'Donovan, M Gill, A Thapar, N Craddoc. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular psychiatry. vol 10. issue 10. 2005-12-23. PMID:15940292. |
association of the paternally transmitted copy of common valine allele of the val66met polymorphism of the brain-derived neurotrophic factor (bdnf) gene with susceptibility to adhd. |
2005-12-23 |
2023-08-12 |
human |
| L Kent, E Green, Z Hawi, A Kirley, F Dudbridge, N Lowe, R Raybould, K Langley, N Bray, M Fitzgerald, M J Owen, M C O'Donovan, M Gill, A Thapar, N Craddoc. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular psychiatry. vol 10. issue 10. 2005-12-23. PMID:15940292. |
genes involved in neuronal development and growth are, thus, important etiological candidates and brain-derived neurotrophic factor (bdnf), has been hypothesized to play a role in the pathogenesis of adhd. |
2005-12-23 |
2023-08-12 |
human |
| L Kent, E Green, Z Hawi, A Kirley, F Dudbridge, N Lowe, R Raybould, K Langley, N Bray, M Fitzgerald, M J Owen, M C O'Donovan, M Gill, A Thapar, N Craddoc. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular psychiatry. vol 10. issue 10. 2005-12-23. PMID:15940292. |
the common val66met functional polymorphism in the human bdnf gene (rs 6265) was genotyped in a collaborative family-based sample of 341 white uk or irish adhd probands and their parents. |
2005-12-23 |
2023-08-12 |
human |
| L Kent, E Green, Z Hawi, A Kirley, F Dudbridge, N Lowe, R Raybould, K Langley, N Bray, M Fitzgerald, M J Owen, M C O'Donovan, M Gill, A Thapar, N Craddoc. Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD. Molecular psychiatry. vol 10. issue 10. 2005-12-23. PMID:15940292. |
our findings support the hypothesis that bdnf is involved in the pathogenesis of adhd. |
2005-12-23 |
2023-08-12 |
human |
| S Friedel, F Fontenla Horro, A K Wermter, F Geller, A Dempfle, K Reichwald, J Smidt, G Brönner, K Konrad, B Herpertz-Dahlmann, A Warnke, U Hemminger, M Linder, H Kiefl, H P Goldschmidt, W Siegfried, H Remschmidt, A Hinney, J Hebebran. Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 132B. issue 1. 2005-05-12. PMID:15457498. |
we searched for the role of bdnf variants in obesity, eating disorders, and attention-deficit/hyperactivity disorder (adhd). |
2005-05-12 |
2023-08-12 |
mouse |
| Shih-Jen Tsa. Attention-deficit hyperactivity disorder and brain-derived neurotrophic factor: a speculative hypothesis. Medical hypotheses. vol 60. issue 6. 2004-01-12. PMID:12699711. |
psychostimulants and antidepressants are the agents commonly used for the treatment of adhd and were also found to elevate central bdnf. |
2004-01-12 |
2023-08-12 |
Not clear |
| Shih-Jen Tsa. Attention-deficit hyperactivity disorder and brain-derived neurotrophic factor: a speculative hypothesis. Medical hypotheses. vol 60. issue 6. 2004-01-12. PMID:12699711. |
it is proposed here that bdnf may play a role in the therapeutic action and pathogenesis of adhd. |
2004-01-12 |
2023-08-12 |
Not clear |