| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Durston, J A Fossella, B J Casey, H E Hulshoff Pol, A Galvan, H G Schnack, M P Steenhuis, R B Minderaa, J K Buitelaar, R S Kahn, H van Engelan. Differential effects of DRD4 and DAT1 genotype on fronto-striatal gray matter volumes in a sample of subjects with attention deficit hyperactivity disorder, their unaffected siblings, and controls. Molecular psychiatry. vol 10. issue 7. 2005-12-07. PMID:15724142. |
we show that the dat1 gene, a gene expressed predominantly in the basal ganglia, preferentially influences caudate volume, whereas the drd4 gene, a gene expressed predominantly in the prefrontal cortex, preferentially influences prefrontal gray matter volume in a sample of subjects including subjects with adhd, their unaffected siblings, and healthy controls. |
2005-12-07 |
2023-08-12 |
human |
| Larry J Seidman, Eve M Valera, Nikos Makri. Structural brain imaging of attention-deficit/hyperactivity disorder. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15949998. |
the most replicated alterations in adhd in childhood include significantly smaller volumes in the dorsolateral prefrontal cortex, caudate, pallidum, corpus callosum, and cerebellum. |
2005-07-29 |
2023-08-12 |
human |
| George Bush, Eve M Valera, Larry J Seidma. Functional neuroimaging of attention-deficit/hyperactivity disorder: a review and suggested future directions. Biological psychiatry. vol 57. issue 11. 2005-07-29. PMID:15949999. |
convergent data from neuroimaging, neuropsychological, genetics, and neurochemical studies have implicated dysfunction of fronto-striatal structures (lateral prefrontal cortex, dorsal anterior cingulate cortex, caudate, and putamen) as likely contributing to the pathophysiology of adhd. |
2005-07-29 |
2023-08-12 |
Not clear |
| Klaus Henning Krause, Stefan H Dresel, Johanna Krause, Christian la Fougere, Manfred Ackenhei. The dopamine transporter and neuroimaging in attention deficit hyperactivity disorder. Neuroscience and biobehavioral reviews. vol 27. issue 7. 2004-01-15. PMID:14624805. |
no differences in dat density between the left and right side and between putamen and caudate nucleus have been found in [99mtc]trodat-1 spect of adhd patients. |
2004-01-15 |
2023-08-12 |
Not clear |
| Gregory W Schrimsher, Rebecca L Billingsley, Edward F Jackson, Bartlett D Moor. Caudate nucleus volume asymmetry predicts attention-deficit hyperactivity disorder (ADHD) symptomatology in children. Journal of child neurology. vol 17. issue 12. 2003-06-04. PMID:12593459. |
caudate nucleus volume asymmetry predicts attention-deficit hyperactivity disorder (adhd) symptomatology in children. |
2003-06-04 |
2023-08-12 |
Not clear |
| Gregory W Schrimsher, Rebecca L Billingsley, Edward F Jackson, Bartlett D Moor. Caudate nucleus volume asymmetry predicts attention-deficit hyperactivity disorder (ADHD) symptomatology in children. Journal of child neurology. vol 17. issue 12. 2003-06-04. PMID:12593459. |
studies comparing children with and without adhd have found differences in the size and symmetry of the caudate nuclei. |
2003-06-04 |
2023-08-12 |
Not clear |
| Gregory W Schrimsher, Rebecca L Billingsley, Edward F Jackson, Bartlett D Moor. Caudate nucleus volume asymmetry predicts attention-deficit hyperactivity disorder (ADHD) symptomatology in children. Journal of child neurology. vol 17. issue 12. 2003-06-04. PMID:12593459. |
using multiple regression, we tested the hypothesis that caudate volume symmetry (log left minus log right caudate volume) measured from serial sagittal magnetic resonance images in a sample of nonreferred children (12 girls/15 boys, 7.0 to 16.6 years, 81 to 129 iq) would predict the cumulative severity of parent-reported adhd diagnostic behaviors beyond variance predicted by age, sex, and level of internalizing problems as measured by the child behavior checklist. |
2003-06-04 |
2023-08-12 |
Not clear |
| Keith E Saylor, Curtis M Buermeyer, Thomas J Spencer, Russell A Barkle. Adaptive changes related to medication treatment of ADHD: listening to parents of children in clinical trials of a novel nonstimulant medication. The Journal of clinical psychiatry. vol 63 Suppl 12. 2003-02-11. PMID:12562058. |
despite the utility of current adhd diagnostic criteria, sophisticated theoretical conceptualizations of the etiology of adhd have described a much more complex disorder that includes a range of neuropsychological impairments (such as working memory deficits and other executive dysfunction) and underlying structural and functional neuropathology (e.g., caudate nucleus volume, frontal lobe activity). |
2003-02-11 |
2023-08-12 |
Not clear |
| David A Pineda, M Adelaida Restrepo, Ruth J Sarmiento, Juan E Gutierrez, Sergio A Vargas, Yakel T Quiroz, George W Hyn. Statistical analyses of structural magnetic resonance imaging of the head of the caudate nucleus in Colombian children with attention-deficit hyperactivity disorder. Journal of child neurology. vol 17. issue 2. 2002-10-29. PMID:11952084. |
magnetic resonance imaging (mri) studies of the caudate nucleus have reported reversal asymmetry and alterations of its size, suggesting a striate cortical disorder related to attention-deficit hyperactivity disorder (adhd). |
2002-10-29 |
2023-08-12 |
human |
| David A Pineda, M Adelaida Restrepo, Ruth J Sarmiento, Juan E Gutierrez, Sergio A Vargas, Yakel T Quiroz, George W Hyn. Statistical analyses of structural magnetic resonance imaging of the head of the caudate nucleus in Colombian children with attention-deficit hyperactivity disorder. Journal of child neurology. vol 17. issue 2. 2002-10-29. PMID:11952084. |
the objective was to evaluate whether alterations of the asymmetry and size of the caudate nucleus head exist in a sample of well-controlled 7- to 11-year-old colombian children, with different types of adhd. |
2002-10-29 |
2023-08-12 |
human |
| M Semrud-Clikeman, R J Steingard, P Filipek, J Biederman, K Bekken, P F Rensha. Using MRI to examine brain-behavior relationships in males with attention deficit disorder with hyperactivity. Journal of the American Academy of Child and Adolescent Psychiatry. vol 39. issue 4. 2000-05-03. PMID:10761350. |
the relationship between neuropsychological measures of inhibition and sustained attention and structural brain differences in the regions of the caudate and the frontal region was examined in males with attention deficit disorder with hyperactivity (add/h). |
2000-05-03 |
2023-08-12 |
Not clear |
| J Swanson, F X Castellanos, M Murias, G LaHoste, J Kenned. Cognitive neuroscience of attention deficit hyperactivity disorder and hyperkinetic disorder. Current opinion in neurobiology. vol 8. issue 2. 1998-09-08. PMID:9635212. |
magnetic resonance imaging (mri) studies have shown that some regions of the frontal lobes (anterior superior and inferior) and basal ganglia (caudate nucleus and globus pallidus) are about 10% smaller in adhd groups than in control groups of children, and molecular genetic studies have shown that diagnosis of adhd is associated with polymorphisms in some dopamine genes (the dopamine d4 receptor gene and the dopamine transporter gene). |
1998-09-08 |
2023-08-12 |
Not clear |
| P A Filipek, M Semrud-Clikeman, R J Steingard, P F Renshaw, D N Kennedy, J Biederma. Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls. Neurology. vol 48. issue 3. 1997-03-28. PMID:9065532. |
to test by mri-based morphometry the a priori hypotheses that developmental anomalies exist in attention-deficit hyperactivity disorder (adhd) in left caudate and right prefrontal/frontal/ and/or posterior parietal hemispheric regions, in accord with neurochemical, neuronal circuitry and attentional network hypotheses, and prior imaging studies. |
1997-03-28 |
2023-08-12 |
human |
| F X Castellanos, J N Giedd, P Eckburg, W L Marsh, A C Vaituzis, D Kaysen, S D Hamburger, J L Rapopor. Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder. The American journal of psychiatry. vol 151. issue 12. 1994-12-20. PMID:7977887. |
because the caudate nuclei receive inputs from cortical regions implicated in executive functioning and attentional tasks, caudate and total brain volumes were examined in boys with attention deficit hyperactivity disorder (adhd) and normal comparison subjects. |
1994-12-20 |
2023-08-12 |
human |
| G W Hynd, K L Hern, E S Novey, D Eliopulos, R Marshall, J J Gonzalez, K K Voelle. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. Journal of child neurology. vol 8. issue 4. 1993-12-22. PMID:8228029. |
based on previous studies that have implicated metabolic deficiencies in the caudate-striatal region in adhd, we employed magnetic resonance imaging to investigate patterns of morphology of the head of the caudate nucleus in normal and adhd children. |
1993-12-22 |
2023-08-12 |
Not clear |
| G W Hynd, K L Hern, E S Novey, D Eliopulos, R Marshall, J J Gonzalez, K K Voelle. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. Journal of child neurology. vol 8. issue 4. 1993-12-22. PMID:8228029. |
in normal children, 72.7% evidenced a left-larger-than-right (l > r) pattern of asymmetry, whereas 63.6% of the adhd children had the reverse (l < r) pattern of asymmetry of the head of the caudate nucleus. |
1993-12-22 |
2023-08-12 |
Not clear |
| G W Hynd, K L Hern, E S Novey, D Eliopulos, R Marshall, J J Gonzalez, K K Voelle. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. Journal of child neurology. vol 8. issue 4. 1993-12-22. PMID:8228029. |
this reversal of normal asymmetry in adhd children was due to a significantly smaller left caudate nucleus. |
1993-12-22 |
2023-08-12 |
Not clear |
| G W Hynd, K L Hern, E S Novey, D Eliopulos, R Marshall, J J Gonzalez, K K Voelle. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. Journal of child neurology. vol 8. issue 4. 1993-12-22. PMID:8228029. |
the reversal in asymmetry of the head of the caudate was most notable in adhd males. |
1993-12-22 |
2023-08-12 |
Not clear |
| G W Hynd, K L Hern, E S Novey, D Eliopulos, R Marshall, J J Gonzalez, K K Voelle. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. Journal of child neurology. vol 8. issue 4. 1993-12-22. PMID:8228029. |
these results suggest that normal (l > r) morphologic asymmetry in the region of the caudate nucleus may be related to asymmetries observed in neurotransmitter systems implicated in adhd. |
1993-12-22 |
2023-08-12 |
Not clear |