| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mariane Vicente, Kwaku Addo-Osafo, Keith Vosse. Latest advances in mechanisms of epileptic activity in Alzheimer's disease and dementia with Lewy Bodies. Frontiers in neurology. vol 15. 2024-02-23. PMID:38390593. |
hyperexcitability could be a biomarker for early detection of ad or dlb before the onset of dementia. |
2024-02-23 |
2024-02-25 |
Not clear |
| Oluwadamilola Omolara Ojo, Sara Bandres-Ciga, Mary B Makarious, Peter Wild Crea, Dena G Hernandez, Henry Houlden, Mie Rizig, Andrew B Singleton, Alastair J Noyce, Mike A Nalls, Cornelis Blauwendraat, Njideka Ulunma Okubadej. GBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians. Movement disorders : official journal of the Movement Disorder Society. 2024-02-23. PMID:38390630. |
rapid eye movement (rem) sleep behavior disorder (rbd) is an early feature of parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-02-23 |
2024-02-25 |
Not clear |
| Patricio Millar Vernetti, Lucy Norcliffe-Kaufmann, Jose-Alberto Palma, Italo Biaggioni, Cyndya A Shibao, Amanda Peltier, Roy Freeman, Christopher Gibbons, David S Goldstein, Phillip A Low, Wolfgang Singer, Elizabeth A Coon, Mitchell G Miglis, Gregor K Wenning, Alessandra Fanciulli, Steven Vernino, Rebecca A Betensky, Horacio Kaufman. Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study. Brain : a journal of neurology. 2024-02-17. PMID:38366572. |
we identified incident cases of parkinson disease (pd), dementia with lewy bodies (dlb), or multiple system atrophy (msa) and computed hazard ratios for phenoconversion as functions of clinical features. |
2024-02-17 |
2024-02-19 |
human |
| Ayumi Matsuki, Yoshihisa Watanabe, Sho Hashimoto, Atsushi Hoshino, Satoaki Matob. Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell. Genes to cells : devoted to molecular & cellular mechanisms. 2024-02-17. PMID:38366711. |
the deposition of α-synuclein (α-syn) fibrils in neuronal cells has been implicated as a causative factor in parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-02-17 |
2024-02-19 |
Not clear |
| Seunghee Na, Dong Woo Kang, Geon Ha Kim, Ko Woon Kim, Yeshin Kim, Hee-Jin Kim, Kee Hyung Park, Young Ho Park, Gihwan Byeon, Jeewon Suh, Joon Hyun Shin, YongSoo Shim, YoungSoon Yang, Yoo Hyun Um, Seong-Il Oh, Sheng-Min Wang, Bora Yoon, Hai-Jeon Yoon, Sun Min Lee, Juyoun Lee, Jin San Lee, Hak Young Rhee, Jae-Sung Lim, Young Hee Jung, Juhee Chin, Yun Jeong Hong, Hyemin Jang, Hongyoon Choi, Miyoung Choi, Jae-Won Jan. The Usefulness of Dementia and neurocognitive disorders. vol 23. issue 1. 2024-02-16. PMID:38362056. |
the usefulness of dementia subtypes, including alzheimer's dementia (ad), dementia with lewy bodies (dlb), and frontotemporal dementia (ftd), pose diagnostic challenges. |
2024-02-16 |
2024-02-18 |
Not clear |
| Mincheol Park, Kyoungwon Baik, Young H Sohn, Byoung Seok Y. Development and Validation of a Screening Questionnaire for Dementia With Lewy Bodies (DLB): the DLB Screening Questionnaire (DLBSQ). Dementia and neurocognitive disorders. vol 23. issue 1. 2024-02-16. PMID:38362053. |
development and validation of a screening questionnaire for dementia with lewy bodies (dlb): the dlb screening questionnaire (dlbsq). |
2024-02-16 |
2024-02-18 |
Not clear |
| Mincheol Park, Kyoungwon Baik, Young H Sohn, Byoung Seok Y. Development and Validation of a Screening Questionnaire for Dementia With Lewy Bodies (DLB): the DLB Screening Questionnaire (DLBSQ). Dementia and neurocognitive disorders. vol 23. issue 1. 2024-02-16. PMID:38362053. |
although dementia with lewy bodies (dlb) is the second most common cause of neurodegenerative dementia, its clinical prevalence is low. |
2024-02-16 |
2024-02-18 |
Not clear |
| Olivier Bousiges, Thomas Lavaux, Catherine Demuynck, Caroline Schaeffer-Agalède, Nathalie Philippi, Candice Muller, Benjamin Cretin, Frédéric Blan. Diagnostic value of CSF chromogranin A to discriminate between Alzheimer's disease and dementia with Lewy bodies. Neuropathology and applied neurobiology. vol 50. issue 1. 2024-02-16. PMID:38363175. |
chromogranin a (cga) seems to be involved in the pathophysiology of different neurodegenerative pathologies such as alzheimer's disease (ad) and dementia with lewy bodies (dlb). |
2024-02-16 |
2024-02-18 |
Not clear |
| Lauren Walker, Harry Simpson, Alan J Thomas, Johannes Attem. Prevalence, distribution, and severity of cerebral amyloid angiopathy differ between Lewy body diseases and Alzheimer's disease. Acta neuropathologica communications. vol 12. issue 1. 2024-02-15. PMID:38360761. |
dementia with lewy bodies (dlb), parkinson's disease dementia (pdd), and parkinson's disease (pd) collectively known as lewy body diseases (lbds) are neuropathologically characterised by α-synuclein deposits (lewy bodies and lewy neurites). |
2024-02-15 |
2024-02-18 |
Not clear |
| Lauren Walker, Harry Simpson, Alan J Thomas, Johannes Attem. Prevalence, distribution, and severity of cerebral amyloid angiopathy differ between Lewy body diseases and Alzheimer's disease. Acta neuropathologica communications. vol 12. issue 1. 2024-02-15. PMID:38360761. |
topographical patterns and severity of caa in dlb more closely resembled ad rather than pdd, and as type 1 caa is associated with clinical dementia in ad, further investigations are warranted into whether the increased presence of type 1 caa in dlb compared to pdd are related to the onset of cognitive symptoms and is a distinguishing factor between lbds. |
2024-02-15 |
2024-02-18 |
Not clear |
| Qijun Li, Junshan Wang, Ruixue Cui, Jing Yua. Identifying Mixed Dementia With Lewy Bodies and Alzheimer Disease Using Multitracer PET Imaging: A Case Study. Clinical nuclear medicine. 2024-02-13. PMID:38350092. |
we reported imaging findings with complex signs that were corresponded with both dementia with lewy bodies (dlb) and alzheimer disease (ad) in the case of a 78-year-old woman. |
2024-02-13 |
2024-02-16 |
Not clear |
| Thomas R Goddard, Keeley J Brookes, Riddhi Sharma, Armaghan Moemeni, Anto P Rajkuma. Dementia with Lewy Bodies: Genomics, Transcriptomics, and Its Future with Data Science. Cells. vol 13. issue 3. 2024-02-09. PMID:38334615. |
dementia with lewy bodies (dlb) is a significant public health issue. |
2024-02-09 |
2024-02-11 |
Not clear |
| El Jeong, Yong Woo Shin, Jung-Ick Byun, Jun-Sang Sunwoo, Monica Roascio, Pietro Mattioli, Laura Giorgetti, Francesco Famà, Gabriele Arnulfo, Dario Arnaldi, Han-Joon Kim, Ki-Young Jun. EEG-based Machine Learning Models for the Prediction of Phenoconversion Time and Subtype in iRBD. Sleep. 2024-02-08. PMID:38330231. |
idiopathic/isolated rapid eye movement sleep behavior disorder (irbd) is a prodromal stage of α-synucleinopathies and eventually phenoconverts to overt neurodegenerative diseases including parkinson's disease (pd), dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2024-02-08 |
2024-02-11 |
Not clear |
| Ahmed A Elbatrawy, Taiwo A Ademoye, Heba Alnakhala, Arati Tripathi, Ashique Zami, Raluca Ostafe, Ulf Dettmer, Jessica S Forti. Discovery of small molecule benzothiazole and indole derivatives tackling tau 2N4R and α-synuclein fibrils. Bioorganic & medicinal chemistry. vol 100. 2024-02-08. PMID:38330847. |
on the other hand, misfolding of α-synuclein (α-syn) is the characteristic feature in pd and dementia with lewy bodies (dlb). |
2024-02-08 |
2024-02-11 |
Not clear |
| Anantharaman Shantaraman, Eric B Dammer, Obiadada Ugochukwu, Duc M Duong, Luming Yin, E Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B Lee, John Q Trojanowski, David A Bennett, James J Lah, Allan I Levey, Nicholas T Seyfried, Lenora Higginbotha. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328211. |
lewy body dementia (lbd), a class of disorders comprising parkinson's disease dementia (pdd) and dementia with lewy bodies (dlb), features substantial clinical and pathological overlap with alzheimer's disease (ad). |
2024-02-08 |
2024-02-10 |
Not clear |
| Myung Jong Kim, Soojin Kim, Thomas Reinheckel, Dimitri Krain. Inhibition of cysteine protease cathepsin Lincreases the level and activity of lysosomal glucocerebrosidase. JCI insight. vol 9. issue 3. 2024-02-08. PMID:38329128. |
loss-of-function variants in the gba1 gene are also the most common genetic risk factor for parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2024-02-08 |
2024-02-10 |
mouse |
| Patricia Diaz-Galvan, Scott A Przybelski, Alicia Algeciras-Schimnich, Dan J Figdore, Timothy G Lesnick, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunter, Clifford R Jack, Paul H Min, Manoj K Jain, Toji Miyagawa, Leah K Forsberg, Julie A Fields, Rodolfo Savica, Jonathan Graff-Radford, Vijay K Ramanan, David T Jones, Hugo Botha, Erik K St Louis, David S Knopman, Neill R Graff-Radford, Tanis J Ferman, Ronald C Petersen, Val J Lowe, Bradley F Boeve, Kejal Kantarc. Plasma biomarkers of Alzheimer's disease in the continuum of dementia with Lewy bodies. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-02-08. PMID:38329197. |
patients with dementia with lewy bodies (dlb) may have alzheimers disease (ad) pathology that can be detected by plasma biomarkers. |
2024-02-08 |
2024-02-10 |
Not clear |
| Ana Carreras Mascaro, Martyna M Grochowska, Valerie Boumeester, Natasja F J Dits, Ece Naz Bilgiҫ, Guido J Breedveld, Leonie Vergouw, Frank Jan de Jong, Martin E van Royen, Vincenzo Bonifati, Wim Mandemaker. LRP10 and α-synuclein transmission in Lewy body diseases. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-02-05. PMID:38315424. |
autosomal dominant variants in lrp10 have been identified in patients with lewy body diseases (lbds), including parkinson's disease (pd), parkinson's disease-dementia (pdd), and dementia with lewy bodies (dlb). |
2024-02-05 |
2024-02-09 |
Not clear |
| Luca Sofia, Federico Massa, Matteo Pardini, Dario Arnaldi, Matteo Bauckneht, Silvia Morbell. Alzheimer's disease (AD) co-pathology in dementia with Lewy bodies (DLB): implications in the disease modification era. European journal of nuclear medicine and molecular imaging. 2024-01-29. PMID:38285205. |
alzheimer's disease (ad) co-pathology in dementia with lewy bodies (dlb): implications in the disease modification era. |
2024-01-29 |
2024-01-31 |
Not clear |
| Juan Huang, Xingxing Yuan, Lin Chen, Binbin Hu, Hui Wang, Ye Wang, Wei Huan. Pathological α-synuclein detected by real-time quaking-induced conversion in synucleinopathies. Experimental gerontology. 2024-01-27. PMID:38280659. |
the α-syn rt-quic assay has demonstrated good sensitivity and specificity in detecting pathological α-syn, particularly in parkinson's disease (pd) and dementia with lewy bodies (dlb) cases, with an accuracy rate of up to 80 %. |
2024-01-27 |
2024-01-30 |
Not clear |