| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Therése Abrahamsson, Bengt Gustafsson, Eric Hans. Synaptic fatigue at the naive perforant path-dentate granule cell synapse in the rat. The Journal of physiology. vol 569. issue Pt 3. 2006-05-04. PMID:16239273. |
the present study has thus identified two forms of synaptic plasticity that contribute to fatigue of synaptic transmission at low frequencies at the developing pp-gc synapse; ampa silencing and a low-frequency depression of release probability. |
2006-05-04 |
2023-08-12 |
rat |
| Christopher Pittenger, Stefania Fasano, David Mazzocchi-Jones, Stephen B Dunnett, Eric R Kandel, Riccardo Brambill. Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 10. 2006-04-13. PMID:16525060. |
in these transgenic mice, corticostriatal long-term potentiation and depression are abolished, indicating that creb function is essential for bidirectional long-term synaptic plasticity in this structure. |
2006-04-13 |
2023-08-12 |
mouse |
| Richard J Siarey, Angela J Villar, Charles J Epstein, Zygmunt Galdzick. Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome. Neuropharmacology. vol 49. issue 1. 2005-11-22. PMID:15992587. |
in this study, we investigated ca1 hippocampal synaptic plasticity, long-term potentiation (ltp) and depression (ltd) in the ts1cje mouse. |
2005-11-22 |
2023-08-12 |
mouse |
| Brad A Grueter, Danny G Winde. Group II and III metabotropic glutamate receptors suppress excitatory synaptic transmission in the dorsolateral bed nucleus of the stria terminalis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 7. 2005-08-09. PMID:15812571. |
the depression evoked by group ii mglur activation may represent a form of synaptic plasticity as prolonged activation of the receptor produces a long-term depression of glutamatergic transmission. |
2005-08-09 |
2023-08-12 |
mouse |
| Ying Wu, Fumiko Kawasaki, Richard W Ordwa. Properties of short-term synaptic depression at larval neuromuscular synapses in wild-type and temperature-sensitive paralytic mutants of Drosophila. Journal of neurophysiology. vol 93. issue 5. 2005-06-13. PMID:15845998. |
these findings reveal novel properties of short-term synaptic depression and suggest that complementary genetic analysis of larval and adult neuromuscular synapses will further define the in vivo mechanisms of neurotransmitter release and short-term synaptic plasticity. |
2005-06-13 |
2023-08-12 |
drosophila_melanogaster |
| Gabriele Putz, Franco Bertolucci, Thomas Raabe, Troy Zars, Martin Heisenber. The S6KII (rsk) gene of Drosophila melanogaster differentially affects an operant and a classical learning task. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 44. 2005-06-09. PMID:15525759. |
this enzyme is part of a family of serine-threonine kinases that in mammals have been implicated in the mapk (mitogen-activated protein kinase) signaling cascade controlling (among other processes) synaptic plasticity (long-term potentiation/long-term depression) and memory formation. |
2005-06-09 |
2023-08-12 |
human |
| Katherine F Y Chan, Zhengping Jia, Patricia A Murphy, W McIntyre Burnham, Miguel A Cortez, O Carter Snea. Learning and memory impairment in rats with chronic atypical absence seizures. Experimental neurology. vol 190. issue 2. 2004-12-29. PMID:15530872. |
in vitro tests of synaptic plasticity revealed impairments in long-term potentiation (ltp), paired-pulse facilitation (ppf), and presynaptic depression (pd). |
2004-12-29 |
2023-08-12 |
rat |
| R S Duma. Pathophysiology of depression: the concept of synaptic plasticity. European psychiatry : the journal of the Association of European Psychiatrists. vol 17 Suppl 3. 2004-07-29. PMID:15177086. |
pathophysiology of depression: the concept of synaptic plasticity. |
2004-07-29 |
2023-08-12 |
Not clear |
| Fan Jia, Xiaoqiao Xie, Yifeng Zho. Short-term depression of synaptic transmission from rat lateral geniculate nucleus to primary visual cortex in vivo. Brain research. vol 1002. issue 1-2. 2004-06-24. PMID:14988046. |
two forms of short-term synaptic plasticity, paired-pulse depression (ppd) and frequency depression, were prominent in the adult rat geniculo-cortical visual pathway in vivo. |
2004-06-24 |
2023-08-12 |
rat |
| Bertalan K Andrásfalvy, Mark A Smith, Thilo Borchardt, Rolf Sprengel, Jeffrey C Mage. Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice. The Journal of physiology. vol 552. issue Pt 1. 2004-05-24. PMID:12878757. |
neurons of the central nervous system (cns) exhibit a variety of forms of synaptic plasticity, including associative long-term potentiation and depression (ltp/d), homeostatic activity-dependent scaling and distance-dependent scaling. |
2004-05-24 |
2023-08-12 |
mouse |
| Michael P Kaplan, Karen S Wilcox, Marc A Dichte. Differences in multiple forms of short-term plasticity between excitatory and inhibitory hippocampal neurons in culture. Synapse (New York, N.Y.). vol 50. issue 1. 2003-12-12. PMID:12872293. |
this short-term synaptic plasticity, elicited by either pairs or short trains of action potentials at moderate frequencies (1-10 hz), may give rise to either depression or facilitation of synaptic transmission. |
2003-12-12 |
2023-08-12 |
Not clear |
| Ryohei Yasuda, Bernardo L Sabatini, Karel Svobod. Plasticity of calcium channels in dendritic spines. Nature neuroscience. vol 6. issue 9. 2003-10-28. PMID:12937422. |
induction of vscc depression blocks theta-burst-induced long-term potentiation (ltp), indicating that postsynaptic action potentials can modulate synaptic plasticity by tuning vsccs. |
2003-10-28 |
2023-08-12 |
rat |
| Pamela C Hebbard, Rebecca R King, Charles W Malsbury, Carolyn W Harle. Two organizational effects of pubertal testosterone in male rats: transient social memory and a shift away from long-term potentiation following a tetanus in hippocampal CA1. Experimental neurology. vol 182. issue 2. 2003-09-16. PMID:12895458. |
these data argue for two organizational effects of pubertal testosterone: (1) ca1 synaptic plasticity shifts away from potentiation toward depression; (2) social memory is reduced. |
2003-09-16 |
2023-08-12 |
rat |
| J Harry Blaise, Joseph D Bronzin. Effects of stimulus frequency and age on bidirectional synaptic plasticity in the dentate gyrus of freely moving rats. Experimental neurology. vol 182. issue 2. 2003-09-16. PMID:12895462. |
our results indicate that both the strength and the direction (ltp or ltd) of synaptic plasticity vary as a function of activation frequency: sustained low-frequency stimulation ranging from 1 to 7 hz results in depression of activated synapses, whereas high-frequency stimulation (30-200 hz) produces potentiation. |
2003-09-16 |
2023-08-12 |
rat |
| Zhonghui Guan, Joung-Hun Kim, Stavros Lomvardas, Kerri Holick, Shiqin Xu, Eric R Kandel, James H Schwart. p38 MAP kinase mediates both short-term and long-term synaptic depression in aplysia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 19. 2003-08-22. PMID:12917365. |
we conclude that p38 kinase, which itself is bidirectionally regulated by fmrfa and 5-ht, acts as a modulator of synaptic plasticity by positively regulating depression and serving as an inhibitory constraint for facilitation. |
2003-08-22 |
2023-08-12 |
aplysia |
| W Senn, N J Buch. Spike-based synaptic plasticity and the emergence of direction selective simple cells: mathematical analysis. Journal of computational neuroscience. vol 14. issue 2. 2003-04-08. PMID:12567013. |
in the companion paper we presented extended simulations showing that the recently observed spike-timing dependent synaptic plasticity can explain the development of simple cell direction selectivity (ds) when simultaneously modifying the synaptic strength and the degree of synaptic depression. |
2003-04-08 |
2023-08-12 |
Not clear |
| W Senn, N J Buch. Spike-based synaptic plasticity and the emergence of direction selective simple cells: mathematical analysis. Journal of computational neuroscience. vol 14. issue 2. 2003-04-08. PMID:12567013. |
here we estimate the spatial shift of the simple cell receptive field (rf) induced by the long-term synaptic plasticity, and the temporal phase advance caused by the short-term synaptic depression in response to drifting grating stimuli. |
2003-04-08 |
2023-08-12 |
Not clear |
| A Kimberley McAlliste. Neurotrophins and cortical development. Results and problems in cell differentiation. vol 39. 2003-04-07. PMID:12353470. |
in turn, the neurotrophins themselves strongly influence both short-term synaptic plasticity and long-term potentiation and depression. |
2003-04-07 |
2023-08-12 |
Not clear |
| Huan-Xin Chen, Steven N Rope. Reduction of spontaneous inhibitory synaptic activity in experimental heterotopic gray matter. Journal of neurophysiology. vol 89. issue 1. 2003-03-26. PMID:12522167. |
short-term synaptic plasticity of stimulus-evoked epscs showed depression in heterotopic neurons and facilitation in control pyramidal neurons. |
2003-03-26 |
2023-08-12 |
rat |
| Sergei Kirischuk, John D Clements, Rosemarie Granty. Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures. The Journal of physiology. vol 543. issue Pt 1. 2003-02-03. PMID:12181284. |
paired pulse depression (ppd) is a common form of short-term synaptic plasticity. |
2003-02-03 |
2023-08-12 |
rat |