| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.) vol 165 issue 2023 36869551 |
in hypothalamus and hippocampus, clock (bmal1 and clock) and tight junction (ocln and tjp2) genes were improved by prebiotics, and corticotropin-releasing hormone receptor genes, crf1 and crf2, were also significantly regulated for mitigation of depression and anxiety caused by sleep deprivation. |
2023-03-04 |
2023-03-06 |
mouse |
| Dimitar Bakalov, Petar Iliev, Zafer Sabit, Radka Tafradjiiska-Hadjiolova, Georgeta Bochev. Attenuation of Hypothyroidism-Induced Cognitive Impairment by Modulating Serotonin Mediation. Veterinary sciences vol 10 issue 2 2023 36851426 |
a staggering amount of research is suggesting that the common denominators in the pathophysiology of depression and the behavior changes in hypothyroidism are the hippocampal complex and the distorted serotonin metabolism. |
2023-02-28 |
2023-03-06 |
rat |
| Shi Yan, Chang Xu, Mengli Yang, Huiqiang Zhang, Ye Cheng, Zeping Xue, Zecong He, Tiantian Wang, Shangying Bai, Gang Wang, Jianping Wu, Zhiqian Tong, Xiang Ca. The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress. Neuropharmacology vol issue 2023 36849038 |
in this study, we observed that agmat expression increased in the ventral hippocampus rather than in the medial prefrontal cortex in the chronic restraint stress (crs) animal model of depression. |
2023-02-27 |
2023-03-06 |
rat |
| Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Iked. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences vol 24 issue 4 2023 36835151 |
transthyretin is commonly upregulated in the hippocampus of two stress-induced depression mouse models. |
2023-02-25 |
2023-03-06 |
mouse |
| Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Iked. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences vol 24 issue 4 2023 36835151 |
chronic stress can affect gene expression in the hippocampus, which alters neural and cerebrovascular functions, thereby contributing to the development of mental disorders such as depression. |
2023-02-25 |
2023-03-06 |
mouse |
| Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Iked. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences vol 24 issue 4 2023 36835151 |
therefore, this study examines hippocampal gene expression in two mouse models of depression induced by forced swim stress (fss) and repeated social defeat stress (r-sds). |
2023-02-25 |
2023-03-06 |
mouse |
| Judy Alper, Rui Feng, Gaurav Verma, Sarah Rutter, Kuang-Han Huang, Long Xie, Paul Yushkevich, Yael Jacob, Stephanie Brown, Marin Kautz, Molly Schneider, Hung-Mo Lin, Lazar Fleysher, Bradley N Delman, Patrick R Hof, James W Murrough, Priti Balchandan. Stress-related reduction of hippocampal subfield volumes in major depressive disorder: A 7-Tesla study. Frontiers in psychiatry vol 14 issue 2023 36816419 |
the objective of this study was to assess volumetric differences in hippocampal subfields between mdd patients globally and healthy controls (hc) as well as between a subset of treatment-resistant depression (trd) patients and hc using automatic segmentation of hippocampal subfields (ashs) software and ultra-high field mri. |
2023-02-23 |
2023-03-06 |
Not clear |
| Yanru Zhu, Feng Wang, Jiatong Han, Yunli Zhao, Miao Yu, Mingyan Ma, Zhiguo Y. Untargeted and targeted mass spectrometry reveal the effects of theanine on the central and peripheral metabolomics of chronic unpredictable mild stress-induced depression in juvenile rats. Journal of pharmaceutical analysis vol 13 issue 1 2023 36816539 |
given the complexity of the pathogenesis of depression, this study investigated the preventive effect and mechanism of l-theanine on depression in juvenile rats by combining serum and hippocampal metabolomic strategies. |
2023-02-23 |
2023-03-06 |
rat |
| Gaoyou Pei, Liguo Xu, Wenhao Huang, Jianjun Yi. Retraction notice to \"The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF\" [Int. Immunopharmacol. 78 (2020) 106076]. International immunopharmacology vol 117 issue 2023 36822080 |
retraction notice to "the protective role of microrna-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing ctgf" [int. |
2023-02-23 |
2023-03-06 |
rat |
| Zhen Zeng, Yingying Dong, Linxuan Zou, Donghao Xu, Xunrong Luo, Tongpeng Chu, Jing Wang, Qingfa Ren, Quanyuan Liu, Xianglin L. GluCEST Imaging and Structural Alterations of the Bilateral Hippocampus in First-Episode and Early-Onset Major Depression Disorder. Journal of magnetic resonance imaging : JMRI vol issue 2023 36808678 |
glucest imaging and structural alterations of the bilateral hippocampus in first-episode and early-onset major depression disorder. |
2023-02-22 |
2023-03-06 |
Not clear |
| Danying Wang, George Parish, Kimron L Shapiro, Simon Hanslmay. Interaction between theta-phase and spike-timing dependent plasticity simulates theta induced memory effects. eNeuro vol issue 2023 36810147 |
rodent studies suggest that spike timing relative to hippocampal theta activity determines whether potentiation or depression of synapses arise. |
2023-02-22 |
2023-03-06 |
human |
| Lei Shi, Zhu Xia, Jiamei Guo, Lixia Wang, Zhiping Peng, Dachuan Qiu, Yi Zhou, Dongdong Zhou, Li Kuang, Tian Qi. Maresin-1 improves LPS-induced depressive-like behavior by inhibiting hippocampal microglial activation. Journal of affective disorders vol issue 2023 36813041 |
); tspo petct scanning showed that maresin-1 reduced the standardized uptake value (suv) of [18\xe2\x80\xaff] dpa-714 in brain regions associated with depression (e.g., hippocampus and pre-frontal cortex), while immunofluorescence of hippocampal and indicated that maresin-1 inhibited microglial activation reducing the expression of the pro-inflammatory cytokine il-1\xce\xb2 and nlrp3. |
2023-02-22 |
2023-03-06 |
mouse |
| Ben Chen, Mingfeng Yang, Xiaomei Zhong, Qiang Wang, Huarong Zhou, Meiling Liu, Min Zhang, Le Hou, Zhangying Wu, Si Zhang, Gaohong Lin, Yuping Nin. Disrupted dynamic functional connectivity of hippocampal subregions mediated the slowed information processing speed in late-life depression. Psychological medicine vol issue 2023 36803969 |
disrupted dynamic functional connectivity of hippocampal subregions mediated the slowed information processing speed in late-life depression. |
2023-02-21 |
2023-03-06 |
Not clear |
| Ben Chen, Mingfeng Yang, Xiaomei Zhong, Qiang Wang, Huarong Zhou, Meiling Liu, Min Zhang, Le Hou, Zhangying Wu, Si Zhang, Gaohong Lin, Yuping Nin. Disrupted dynamic functional connectivity of hippocampal subregions mediated the slowed information processing speed in late-life depression. Psychological medicine vol issue 2023 36803969 |
the hippocampus is an important link between depression and dementia, and it may be involved in ips slowing in lld. |
2023-02-21 |
2023-03-06 |
Not clear |
| Kuo Zhang, Fan Wang, Mengying Zhai, Meiyao He, Yuxuan Hu, Lijin Feng, Yuting Li, Jingyu Yang, Chunfu W. Hyperactive neuronal autophagy depletes BDNF and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression. Theranostics vol 13 issue 3 2023 36793868 |
hyperactive neuronal autophagy depletes bdnf and impairs adult hippocampal neurogenesis in a corticosterone-induced mouse model of depression. |
2023-02-16 |
2023-03-06 |
mouse |
| Chen-Chen Li, Fan Ye, Chen-Xi Xu, Ning Jiang, Qi Chang, Xin-Min Liu, Rui-Le Pa. Tryptophan-kynurenine metabolic characterization in the gut and brain of depressive-like rats induced by chronic restraint stress. Journal of affective disorders vol issue 2023 36746244 |
after depression behavior tests, seven segments (cortex, hippocampus, striatum, hypothalamus, serum, cecum, and colon) along the gut-brain axis were collected to characterize their kp metabolism. |
2023-02-06 |
2023-03-06 |
rat |
| Guo-Liang Dai, Hua-Xi Hang, Pei-Yao Chen, Sheng-Wei Hong, Mei-Juan Xu, Cheng-Yao Ma, Qian Huang, Yu Ye, Mei-Shuang Yu, Wen-Zheng J. [Anti-depression mechanism of Zuojin Pills:based on UHPLC-TOF-MS, network pharmacology, and experimental verification]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica vol 48 issue 1 2023 36725270 |
furthermore, the results of animal experiments showed that zuojin pills could significantly improve the depression behaviors of depression, reduce the levels of il-1\xce\xb2, il-6 and tnf-\xce\xb1 in hippocampus and serum, activate ampk/sirt1 signaling, and reduce the protein expression of nlrp3. |
2023-02-01 |
2023-03-06 |
mouse |
| Guo-Liang Dai, Hua-Xi Hang, Pei-Yao Chen, Sheng-Wei Hong, Mei-Juan Xu, Cheng-Yao Ma, Qian Huang, Yu Ye, Mei-Shuang Yu, Wen-Zheng J. [Anti-depression mechanism of Zuojin Pills:based on UHPLC-TOF-MS, network pharmacology, and experimental verification]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica vol 48 issue 1 2023 36725270 |
in conclusion, zuojin pills may play a role in the treatment of depression by activating ampk/sirt1 signaling pathway, and inhibiting nlrp3 activation and neuroinflammation in the hippocampus of mice. |
2023-02-01 |
2023-03-06 |
mouse |
| Shuo Wu, Kuan Ning, Yujun Wang, Lesha Zhang, Jinggen Li. Up-regulation of BDNF/TrkB signaling by \\xce\\xb4 opioid receptor agonist SNC80 modulates depressive-like behaviors in chronic restraint-stressed mice. European journal of pharmacology vol issue 2023 36708979 |
it was found that the hippocampus and amygdala were involved in crs-induced depression. |
2023-01-28 |
2023-01-31 |
mouse |
| Shuo Wu, Kuan Ning, Yujun Wang, Lesha Zhang, Jinggen Li. Up-regulation of BDNF/TrkB signaling by \\xce\\xb4 opioid receptor agonist SNC80 modulates depressive-like behaviors in chronic restraint-stressed mice. European journal of pharmacology vol issue 2023 36708979 |
therefore, the present study demonstrates that snc80 exerts anti-depressant effects by up-regulating the bdnf/trkb signaling pathway in the hippocampus and amygdala in crs-induced depression and provides evidence that \xce\xb4or's agonists may be potential anti-depressant therapeutic agents. |
2023-01-28 |
2023-01-31 |
mouse |