| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tina Gupta, Helmet T Karim, Neil P Jones, Fabio Ferrarelli, Melissa Nance, Stephan F Taylor, David Rogers, Ashley M Pogue, T H Stanley Seah, Mary L Phillips, Neal D Ryan, Erika E Forbe. Continuous theta burst stimulation to dorsomedial prefrontal cortex in young adults with depression: Changes in resting frontostriatal functional connectivity relevant to positive mood. Behaviour research and therapy. vol 174. 2024-02-13. PMID:38350221. |
depression has consistently been associated with higher dorsomedial prefrontal cortex (dmpfc) activation, a region that regulates pa through ventral striatum (vs) connections. |
2024-02-13 |
2024-02-16 |
Not clear |
| Han-Yu Zhou, Lan Zhou, Tong-Xuan Zheng, Li-Ping Ma, Ming-Xia Fan, Liang Liu, Xu-Dong Zhao, Chao Ya. Unraveling the link between childhood maltreatment and depression: Insights from the role of ventral striatum and middle cingulate cortex in hedonic experience and emotion regulation. Development and psychopathology. 2024-01-05. PMID:38179683. |
unraveling the link between childhood maltreatment and depression: insights from the role of ventral striatum and middle cingulate cortex in hedonic experience and emotion regulation. |
2024-01-05 |
2024-01-07 |
Not clear |
| Jesper Lindahl, Marie Asp, Darya Ståhl, Johanna Tjernberg, Moa Eklund, Johannes Björkstrand, Danielle van Westen, Jimmy Jensen, Kristoffer Månsson, Åsa Tornberg, Martina Svensson, Tomas Deierborg, Filip Ventorp, Daniel Lindqvis. Add-on pramipexole for anhedonic depression: study protocol for a randomised controlled trial and open-label follow-up in Lund, Sweden. BMJ open. vol 13. issue 11. 2023-11-30. PMID:38035737. |
we recently showed, in an open-label pilot study, that add-on pramipexole is a feasible treatment for depression with significant anhedonia, and that pramipexole increases reward-related activity in the ventral striatum. |
2023-11-30 |
2023-12-10 |
Not clear |
| Yun-Feng Zhang, Jialiang Wu, Yingqi Wang, Natalie L Johnson, Janardhan P Bhattarai, Guanqing Li, Wenqiang Wang, Camilo Guevara, Hannah Shoenhard, Marc V Fuccillo, Daniel W Wesson, Minghong M. Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice. Nature communications. vol 14. issue 1. 2023-10-30. PMID:37898623. |
the ventral striatum is a reward center implicated in the pathophysiology of depression. |
2023-10-30 |
2023-11-08 |
mouse |
| Sameer Hassama. Chronic stress, neuroinflammation, and depression: an overview of pathophysiological mechanisms and emerging anti-inflammatories. Frontiers in psychiatry. vol 14. 2023-05-30. PMID:37252156. |
neural circuitry dysfunction such as hypoactivation between the ventral striatum and the ventromedial prefrontal cortex underlies the melancholic phenotype of depression. |
2023-05-30 |
2023-08-14 |
Not clear |
| Zachary Anderson, Katherine S F Damme, Ann L Carroll, Iris Ka-Yi Chat, Katherine S Young, Michelle G Craske, Susan Bookheimer, Richard Zinbarg, Robin Nussloc. Association between reward-related functional connectivity and tri-level mood and anxiety symptoms. NeuroImage. Clinical. vol 37. 2023-02-03. PMID:36736199. |
depression and anxiety are associated with abnormalities in brain regions that process rewards including the medial orbitofrontal cortex (mofc), the ventral striatum (vs), and the amygdala. |
2023-02-03 |
2023-08-14 |
human |
| Stéphane Prange, Hélène Klinger, Chloé Laurencin, Teodor Danaila, Stéphane Thoboi. Depression in Patients with Parkinson's Disease: Current Understanding of its Neurobiology and Implications for Treatment. Drugs & aging. 2022-06-15. PMID:35705848. |
in particular, the evolution of serotonergic, noradrenergic, and dopaminergic dysfunction and abnormalities of limbic circuits across time, involving the anterior cingulate and orbitofrontal cortices, amygdala, thalamus and ventral striatum, help to delineate the variable expression of depression in patients with prodromal, early and advanced pd. |
2022-06-15 |
2023-08-14 |
Not clear |
| Pedro Mario Pan, João R Sato, Marie-Laure Paillère Martinot, Jean-Luc Martinot, Eric Artiges, Jani Penttilä, Yvonne Grimmer, Betteke M van Noort, Andreas Becker, Tobias Banaschewski, Arun L W Bokde, Sylvane Desrivières, Herta Flor, Hugh Garavan, Bernd Ittermann, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Juliane H Fröhner, Robert Whelan, Gunter Schumann, Margaret L Westwater, Christian Grillon, Hugo Cogo-Moreira, Argyris Stringaris, Monique Erns. Longitudinal Trajectory of the Link Between Ventral Striatum and Depression in Adolescence. The American journal of psychiatry. 2022-05-18. PMID:35582783. |
longitudinal trajectory of the link between ventral striatum and depression in adolescence. |
2022-05-18 |
2023-08-13 |
Not clear |
| Pedro Mario Pan, João R Sato, Marie-Laure Paillère Martinot, Jean-Luc Martinot, Eric Artiges, Jani Penttilä, Yvonne Grimmer, Betteke M van Noort, Andreas Becker, Tobias Banaschewski, Arun L W Bokde, Sylvane Desrivières, Herta Flor, Hugh Garavan, Bernd Ittermann, Frauke Nees, Dimitri Papadopoulos Orfanos, Luise Poustka, Juliane H Fröhner, Robert Whelan, Gunter Schumann, Margaret L Westwater, Christian Grillon, Hugo Cogo-Moreira, Argyris Stringaris, Monique Erns. Longitudinal Trajectory of the Link Between Ventral Striatum and Depression in Adolescence. The American journal of psychiatry. 2022-05-18. PMID:35582783. |
research in adolescent depression has found aberrant intrinsic functional connectivity (ifc) among the ventral striatum (vs) and several brain regions implicated in reward processing. |
2022-05-18 |
2023-08-13 |
Not clear |
| Emilio Merlo Pich, Laura Cavalleri, Caterina Toma, Ginetta Coll. Involvement of DA D3 Receptors in Structural Neuroplasticity of Selected Limbic Brain Circuits: Possible Role in Treatment-Resistant Depression. Current topics in behavioral neurosciences. 2022-05-10. PMID:35538302. |
since in mood disorders, depression and anhedonia have been proposed to be associated with impaired neuroplasticity and reduced daergic tone in brain circuits connecting prefrontal cortex, ventral striatum, amygdala, and ventral mesencephalon, activation of d3 receptors could provide a therapeutic benefit. |
2022-05-10 |
2023-08-13 |
human |
| Hui Wang, Jianxia Xu, Miao Yu, Xianjun Ma, Yuqian Li, Chenxi Pan, Jingru Ren, Weiguo Li. Altered functional connectivity of ventral striatum subregions in de-novo parkinson's disease with depression. Neuroscience. 2022-03-31. PMID:35358647. |
altered functional connectivity of ventral striatum subregions in de-novo parkinson's disease with depression. |
2022-03-31 |
2023-08-13 |
Not clear |
| Katherine S Young, Camilla Ward, Meghan Vinograd, Kelly Chen, Susan Y Bookheimer, Robin Nusslock, Richard E Zinbarg, Michelle G Crask. Individual differences in threat and reward neural circuitry activation: testing dimensional models of early adversity, anxiety and depression. The European journal of neuroscience. 2022-01-06. PMID:34989038. |
we examined functional brain activity during a face processing task in threat (amygdala, ventromedial prefrontal cortex) and reward (ventral striatum, orbitofrontal cortex) regions of interest among a sample (n = 103) of young adults (aged 18-19 years) in relation to dimensional measures of early life adversity and symptoms of anxiety and depression. |
2022-01-06 |
2023-08-13 |
Not clear |
| Mandakh Bekhbat, Michael T Treadway, Jennifer C Felge. Inflammation as a Pathophysiologic Pathway to Anhedonia: Mechanisms and Therapeutic Implications. Current topics in behavioral neurosciences. 2021-12-31. PMID:34971449. |
consistent with laboratory studies involving exogenous administration of peripheral inflammatory stimuli, neuroimaging studies have further confirmed that increased endogenous inflammation in depression is associated with decreased activation of and reduced functional connectivity within reward circuits involving ventral striatum and ventromedial prefrontal cortex in association with anhedonia. |
2021-12-31 |
2023-08-13 |
Not clear |
| Erin Bondy, David A A Baranger, Jared Balbona, Kendall Sputo, Sarah E Paul, Thomas F Oltmanns, Ryan Bogda. Neuroticism and reward-related ventral striatum activity: Probing vulnerability to stress-related depression. Journal of abnormal psychology. vol 130. issue 3. 2021-07-05. PMID:33539118. |
neuroticism and reward-related ventral striatum activity: probing vulnerability to stress-related depression. |
2021-07-05 |
2023-08-13 |
Not clear |
| Erin Bondy, David A A Baranger, Jared Balbona, Kendall Sputo, Sarah E Paul, Thomas F Oltmanns, Ryan Bogda. Neuroticism and reward-related ventral striatum activity: Probing vulnerability to stress-related depression. Journal of abnormal psychology. vol 130. issue 3. 2021-07-05. PMID:33539118. |
using data from the saint louis personality and aging network (span) study and duke neurogenetics study (dns), we examined whether neuroticism moderates links between stressful life events (sle) and depression as well as sles and ventral striatum (vs) response to reward. |
2021-07-05 |
2023-08-13 |
Not clear |
| Tsafrir Greenberg, Jay C Fournier, Richelle Stiffler, Henry W Chase, Jorge R Almeida, Haris Aslam, Thilo Deckersbach, Crystal Cooper, Marisa S Toups, Tom Carmody, Benji Kurian, Scott Peltier, Phillip Adams, Melvin G McInnis, Maria A Oquendo, Maurizio Fava, Ramin Parsey, Patrick J McGrath, Myrna Weissman, Madhukar Trivedi, Mary L Phillip. Reward related ventral striatal activity and differential response to sertraline versus placebo in depressed individuals. Molecular psychiatry. vol 25. issue 7. 2021-03-17. PMID:31462766. |
we tested whether an index of reward system function in the ventral striatum (vs), a key reward circuitry region, moderated differential response to sertraline versus placebo, assessed with the hamilton rating scale for depression (hsrd) over 8 weeks. |
2021-03-17 |
2023-08-13 |
Not clear |
| Chantal Martin-Soelch, Matthias Guillod, Claudie Gaillard, Romina Evelyn Recabarren, Andrea Federspiel, Christoph Mueller-Pfeiffer, Philipp Homan, Gregor Hasler, Dominik Schoebi, Antje Horsch, Patrick Gome. Increased Reward-Related Activation in the Ventral Striatum During Stress Exposure Associated With Positive Affect in the Daily Life of Young Adults With a Family History of Depression. Preliminary Findings. Frontiers in psychiatry. vol 11. 2021-02-16. PMID:33584359. |
increased reward-related activation in the ventral striatum during stress exposure associated with positive affect in the daily life of young adults with a family history of depression. |
2021-02-16 |
2023-08-13 |
Not clear |
| Jin-Young Park, So Young Park, Hyejin Kwon, Yumi Song, Boin Yun, Yubin Lee, Yeryung Cho, Ahran Joo, Pyung-Lim Ha. A Group of Descending Glutamatergic Neurons Activated by Stress in Corticolimbic Regions Project to the Nucleus Accumbens. Experimental neurobiology. vol 27. issue 5. 2020-10-01. PMID:30429648. |
the nucleus accumbens (nac) is the major component of the ventral striatum that regulates stress-induced depression. |
2020-10-01 |
2023-08-13 |
mouse |
| b' Hanneke Geugies, Roel J T Mocking, Caroline A Figueroa, Paul F C Groot, Jan-Bernard C Marsman, Michelle N Servaas, J Douglas Steele, Aart H Schene, Henricus G Ruh\\xc3\\xa. Impaired reward-related learning signals in remitted unmedicated patients with recurrent depression. Brain : a journal of neurology. vol 142. issue 8. 2020-05-19. PMID:31280309.' |
we used a pavlovian classical conditioning functional mri task to explore the relationship between anhedonia and the temporal difference-related response of the ventral tegmental area and ventral striatum in medication-free remitted recurrent depression patients (n = 36) versus healthy control subjects (n = 27). |
2020-05-19 |
2023-08-13 |
human |
| Marlen Z Gonzalez, Meghan H Puglia, James P Morris, Jessica J Connell. Oxytocin receptor genotype and low economic privilege reverses ventral striatum-social anxiety association. Social neuroscience. vol 14. issue 1. 2019-06-10. PMID:29125397. |
oxytocin receptor gene (oxtr) polymorphisms, lower ventral striatum (vs) response to social stimuli, and lower economic privilege have been independently associated with depression and anxiety. |
2019-06-10 |
2023-08-13 |
human |