| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I V Ekimova, A R Gazizova, M N Karpenko, D V Plaksin. [Signs of anhedonia and destructive changes in the ventral tegmental area of the midbrain in the model of the preclinical Parkinson's disease stage in experiment]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 118. issue 9. 2019-03-25. PMID:30335074. |
the signs of depression may be an early marker of pd, signaling the onset of neurodegeneration in the mesolimbic brain system and increasing functional deficit of the da-ergic transmission in the ventral striatum. |
2019-03-25 |
2023-08-13 |
rat |
| Yong-Ku Kim, Kyoung-Sae N. Application of machine learning classification for structural brain MRI in mood disorders: Critical review from a clinical perspective. Progress in neuro-psychopharmacology & biological psychiatry. vol 80. issue Pt B. 2018-07-10. PMID:28648568. |
the prefrontal cortex, hippocampus, amygdala, thalamus, ventral striatum, and corpus callosum are associated with depression and bipolar disorder. |
2018-07-10 |
2023-08-13 |
Not clear |
| Sophie R DelDonno, Lisanne M Jenkins, Natania A Crane, Robin Nusslock, Kelly A Ryan, Stewart A Shankman, K Luan Phan, Scott A Langenecke. Affective traits and history of depression are related to ventral striatum connectivity. Journal of affective disorders. vol 221. 2018-03-06. PMID:28633048. |
affective traits and history of depression are related to ventral striatum connectivity. |
2018-03-06 |
2023-08-13 |
Not clear |
| Andreas Heinz, Florian Schlagenhauf, Anne Beck, Carolin Wackerhage. Dimensional psychiatry: mental disorders as dysfunctions of basic learning mechanisms. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 8. 2018-01-26. PMID:27145766. |
with respect to negative mood states, it has been shown that both reduced functional activation of the ventral striatum elicited by reward-predicting stimuli and stress-associated activation of the hypothalamic-pituitary-adrenal axis in interaction with reduced serotonin transporter availability and increased amygdala activation by aversive cues contribute to clinical depression; altogether these observations support the notion that basic learning mechanisms, such as pavlovian and instrumental conditioning and pavlovian-to-instrumental transfer, represent a basic dimension of mental disorders that can be mechanistically characterized using computational modeling and associated with specific clinical syndromes across established nosological boundaries. |
2018-01-26 |
2023-08-13 |
Not clear |
| Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Gonzalo Arrondo, Trevor W Robbins, Luke Clark, Paul C Fletcher, Graham K Murra. Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26708106. |
there was reduced activation in the orbitofrontal cortex, ventral striatum, inferior temporal gyrus, and occipital cortex in both depression and schizophrenia in comparison with healthy participants during receipt of unexpected reward. |
2018-01-15 |
2023-08-13 |
human |
| Yang Qu, Andrew J Fuligni, Adriana Galván, Matthew D Lieberman, Eva H Telze. Links between parental depression and longitudinal changes in youths' neural sensitivity to rewards. Social cognitive and affective neuroscience. vol 11. issue 8. 2017-11-09. PMID:27013103. |
longitudinal increases in adolescents' ventral striatum activation mediates the link between greater parental depression and increases in adolescents' risk taking and externalizing behavior. |
2017-11-09 |
2023-08-13 |
Not clear |
| Anup Sharma, Theodore D Satterthwaite, Lillie Vandekar, Natalie Katchmar, Aylin Daldal, Kosha Ruparel, Mark A Elliott, Claudia Baldassano, Michael E Thase, Raquel E Gur, Joseph W Kable, Daniel H Wol. Divergent relationship of depression severity to social reward responses among patients with bipolar versus unipolar depression. Psychiatry research. Neuroimaging. vol 254. 2017-11-09. PMID:27295401. |
however, greater depression severity significantly correlated with reduced bilateral ventral striatum activation to social reward in the bipolar depressed group, but not the unipolar depressed group. |
2017-11-09 |
2023-08-13 |
human |
| Shannon D Donofry, Kathryn A Roecklein, Jennifer E Wildes, Megan A Miller, Kirk I Erickso. Alterations in emotion generation and regulation neurocircuitry in depression and eating disorders: A comparative review of structural and functional neuroimaging studies. Neuroscience and biobehavioral reviews. vol 68. 2017-10-20. PMID:27422451. |
our review of the literature suggests that depression and eds exhibit common structural and functional alterations in brain regions involved in emotion regulation, including the amygdala, ventral striatum and nucleus accumbens, anterior cingulate cortex, insula, and dorsolateral prefrontal cortex. |
2017-10-20 |
2023-08-13 |
Not clear |
| Reut Avinun, Adam Nevo, Annchen R Knodt, Maxwell L Elliott, Spenser R Radtke, Bartholomew D Brigidi, Ahmad R Harir. Reward-Related Ventral Striatum Activity Buffers against the Experience of Depressive Symptoms Associated with Sleep Disturbances. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 40. 2017-10-12. PMID:28924013. |
reward-related brain function, particularly the activity of the ventral striatum (vs), has been identified as a potential buffer against stress-related depression. |
2017-10-12 |
2023-08-13 |
Not clear |
| Zengjian Wang, Xiaoyun Wang, Jian Liu, Jun Chen, Xian Liu, Guangning Nie, Kristen Jorgenson, Ki Cheul Sohn, Ruiwang Huang, Ming Liu, Bo Liu, Jian Kon. Acupuncture treatment modulates the corticostriatal reward circuitry in major depressive disorder. Journal of psychiatric research. vol 84. 2017-09-11. PMID:27693978. |
the increased rsfc between the inferior ventral striatum and medial prefrontal cortex, ventral rostral putamen and amygdala/parahippocampus were significantly positively associated with decreased clinical scores (montgomery-Åsberg depression rating scale and self-rating depression scale scores) at the end of the eight-week treatment. |
2017-09-11 |
2023-08-13 |
Not clear |
| Ramesh Chandra, T Chase Francis, Hyungwoo Nam, Lace M Riggs, Michel Engeln, Sarah Rudzinskas, Prasad Konkalmatt, Scott J Russo, Gustavo Turecki, Sergio D Iniguez, Mary Kay Lob. Reduced Slc6a15 in Nucleus Accumbens D2-Neurons Underlies Stress Susceptibility. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 27. 2017-08-18. PMID:28576941. |
however, no study examined slc6a15 in the ventral striatum [nucleus accumbens (nac)] in depression. |
2017-08-18 |
2023-08-13 |
mouse |
| J W Hwang, S C Xin, Y M Ou, W Y Zhang, Y L Liang, J Chen, X Q Yang, X Y Chen, T W Guo, X J Yang, W H Ma, J Li, B C Zhao, Y Tu, J Kon. Enhanced default mode network connectivity with ventral striatum in subthreshold depression individuals. Journal of psychiatric research. vol 76. 2016-12-13. PMID:26922247. |
enhanced default mode network connectivity with ventral striatum in subthreshold depression individuals. |
2016-12-13 |
2023-08-13 |
Not clear |
| J W Hwang, S C Xin, Y M Ou, W Y Zhang, Y L Liang, J Chen, X Q Yang, X Y Chen, T W Guo, X J Yang, W H Ma, J Li, B C Zhao, Y Tu, J Kon. Enhanced default mode network connectivity with ventral striatum in subthreshold depression individuals. Journal of psychiatric research. vol 76. 2016-12-13. PMID:26922247. |
in addition, we also found the fc between the dmn and ventral striatum was positively and significantly associated with scores on the center for epidemiologic studies depression scale (ces-d), a measurement of depressive symptomatology. |
2016-12-13 |
2023-08-13 |
Not clear |
| M Bauer, S Berman, T Stamm, M Plotkin, M Adli, M Pilhatsch, E D London, G S Hellemann, P C Whybrow, F Schlagenhau. Levothyroxine effects on depressive symptoms and limbic glucose metabolism in bipolar disorder: a randomized, placebo-controlled positron emission tomography study. Molecular psychiatry. vol 21. issue 2. 2016-10-19. PMID:25600111. |
the groups differed significantly in the relationship between the changes in depression scores and in activity in the thalamus bilaterally and the left ventral striatum. |
2016-10-19 |
2023-08-13 |
Not clear |
| Eva H Telze. Dopaminergic reward sensitivity can promote adolescent health: A new perspective on the mechanism of ventral striatum activation. Developmental cognitive neuroscience. vol 17. 2016-09-12. PMID:26708774. |
i review several studies showing that ventral striatum activation serves an adaptive function for adolescents' health and well being relating to declines in both risk taking and depression and increases in cognitive persistence and achievement. |
2016-09-12 |
2023-08-13 |
Not clear |
| Theodore D Satterthwaite, Joseph W Kable, Lillie Vandekar, Natalie Katchmar, Danielle S Bassett, Claudia F Baldassano, Kosha Ruparel, Mark A Elliott, Yvette I Sheline, Ruben C Gur, Raquel E Gur, Christos Davatzikos, Ellen Leibenluft, Michael E Thase, Daniel H Wol. Common and Dissociable Dysfunction of the Reward System in Bipolar and Unipolar Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25767910. |
across disorders, depression severity was significantly associated with reduced activation for wins compared with losses in bilateral ventral striatum, anterior cingulate cortex, posterior cingulate cortex, and right anterior insula. |
2016-04-26 |
2023-08-13 |
human |
| Theodore D Satterthwaite, Joseph W Kable, Lillie Vandekar, Natalie Katchmar, Danielle S Bassett, Claudia F Baldassano, Kosha Ruparel, Mark A Elliott, Yvette I Sheline, Ruben C Gur, Raquel E Gur, Christos Davatzikos, Ellen Leibenluft, Michael E Thase, Daniel H Wol. Common and Dissociable Dysfunction of the Reward System in Bipolar and Unipolar Depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 9. 2016-04-26. PMID:25767910. |
resting-state connectivity within this reward network was also diminished in proportion to depression severity, most notably connectivity strength in the left ventral striatum. |
2016-04-26 |
2023-08-13 |
human |
| Daniel Rial, Cristina Lemos, Helena Pinheiro, Joana M Duarte, Francisco Q Gonçalves, Joana I Real, Rui D Prediger, Nélio Gonçalves, Catarina A Gomes, Paula M Canas, Paula Agostinho, Rodrigo A Cunh. Depression as a Glial-Based Synaptic Dysfunction. Frontiers in cellular neuroscience. vol 9. 2016-02-02. PMID:26834566. |
recent studies combining pharmacological, behavioral, electrophysiological and molecular approaches indicate that depression results from maladaptive neuroplastic processes occurring in defined frontolimbic circuits responsible for emotional processing such as the prefrontal cortex, hippocampus, amygdala and ventral striatum. |
2016-02-02 |
2023-08-13 |
Not clear |
| J Straub, P L Plener, N Sproeber, L Sprenger, M G Koelch, G Groen, B Able. Neural correlates of successful psychotherapy of depression in adolescents. Journal of affective disorders. vol 183. 2016-01-12. PMID:26025370. |
given the concordance of the ventral striatum, amygdala, hippocampus and the subgenual anterior cingulate cortex (sgacc) as correlates of depression and their involvement in reward processing, we used functional magnetic resonance imaging (fmri) during performance of a monetary reward task in an intervention versus waitlist-control design to investigate the clinical and neural effects of cognitive behavioral group therapy (cbt-g). |
2016-01-12 |
2023-08-13 |
Not clear |
| Bonnie Goff, Nim Tottenha. Early-life adversity and adolescent depression: mechanisms involving the ventral striatum. CNS spectrums. vol 20. issue 4. 2015-11-09. PMID:25511634. |
early-life adversity and adolescent depression: mechanisms involving the ventral striatum. |
2015-11-09 |
2023-08-13 |
Not clear |