| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole M Gautier, Edward Glasscoc. Spontaneous seizures in Kcna1-null mice lacking voltage-gated Kv1.1 channels activate Fos expression in select limbic circuits. Journal of neurochemistry. vol 135. issue 1. 2016-01-08. PMID:26112121. |
mice lacking voltage-gated kv1.1 channels as a result of deletion of the kcna1 gene are an extensively utilized genetic model of human epilepsy and sudden unexpected death in epilepsy because of their frequent seizures and genotypic-phenotypic similarity to the human condition. |
2016-01-08 |
2023-08-13 |
mouse |
| Rohit Shankar, David Cox, Virupakshi Jalihal, Scott Brown, Jane Hanna, Brendan McLea. Sudden unexpected death in epilepsy (SUDEP): development of a safety checklist. Seizure. vol 22. issue 10. 2014-07-10. PMID:23962523. |
epilepsy-related death, particularly sudden unexpected death in epilepsy (sudep), is still underestimated by healthcare professionals and this may reflect the mistaken belief that epilepsy is a benign condition. |
2014-07-10 |
2023-08-12 |
Not clear |
| Yakup Ergul, Baris Ekici, Burak Tatli, Kemal Nisli, Meral Ozme. QT and P wave dispersion and heart rate variability in patients with Dravet syndrome. Acta neurologica Belgica. vol 113. issue 2. 2013-10-22. PMID:23065439. |
scn1a mutations are found in up to 80 % of patients with dravet syndrome (ds), and the sudden unexpected death in epilepsy (sudep) rate is higher in ds than in most forms of severe epilepsy. |
2013-10-22 |
2023-08-12 |
human |
| Dale C Hesdorffer, Vicki Beck, Charles E Begley, Malachy L Bishop, Sandra Cushner-Weinstein, Gregory L Holmes, Patricia O Shafer, Joseph I Sirven, Joan K Austi. Research implications of the Institute of Medicine Report, Epilepsy Across the Spectrum: Promoting Health and Understanding. Epilepsia. vol 54. issue 2. 2013-04-02. PMID:23294462. |
for this article, the authors selected one research priority from each of the major chapter themes in the iom report: expanding and improving the quality of epidemiologic surveillance in epilepsy; developing improved interventions for people with epilepsy and depression; expanding early identification/screening for learning impairments in children with epilepsy; evaluating and promoting effective innovative teaching strategies; accelerating research on the identification of risk factors and interventions that increase employment and improve quality of life for people with epilepsy and their families; assessing the information needs of people with epilepsy and their families associated with epilepsy-related risks, specifically sudden unexpected death in epilepsy; and developing and conducting surveys to capture trends in knowledge, awareness, attitudes, and beliefs about epilepsy over time and in specific population subgroups. |
2013-04-02 |
2023-08-12 |
human |
| George B Richerson, Gordon F Buchana. The serotonin axis: Shared mechanisms in seizures, depression, and SUDEP. Epilepsia. vol 52 Suppl 1. 2011-01-31. PMID:21214537. |
we propose that postictal dysfunction of 5-ht neurons causes depression of breathing and arousal in some epilepsy patients, and this can lead to sudden unexpected death in epilepsy (sudep). |
2011-01-31 |
2023-08-12 |
Not clear |
| Carla A Scorzai, Roberta M Cysneiros, Ricardo M Arida, Vera C Terra, Hélio R Machado, Antonio-Carlos G de Almeida, Esper A Cavalheiro, Fulvio A Scorz. Alcohol consumption and sudden unexpected death in epilepsy: experimental approach. Arquivos de neuro-psiquiatria. vol 67. issue 4. 2010-09-01. PMID:20069209. |
using the pilocarpine model of epilepsy, we investigated the effects of alcohol consumption on the frequency of seizures in animals with epilepsy as well the underlying a possible association between alcohol intake and sudden unexpected death in epilepsy (sudep) occurrence. |
2010-09-01 |
2023-08-12 |
rat |