| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Deng, Wen Zheng, Zhi Son. The genetics and molecular biology of fever-associated seizures or epilepsy. Expert reviews in molecular medicine. vol 20. 2018-12-13. PMID:29661262. |
it is common in infants and children, and generally includes febrile seizures (fs), febrile seizures plus (fs+), dravet syndrome (ds) and genetic epilepsy with febrile seizures plus (gefsp). |
2018-12-13 |
2023-08-13 |
Not clear |
| Stéphane Auvin, Mohamed Jeljeli, Béatrice Desnous, Nadia Soussi-Yanicostas, Pascal Dournaud, Ghislaine Sterker. Altered vaccine-induced immunity in children with Dravet syndrome. Epilepsia. vol 59. issue 4. 2018-12-11. PMID:29512885. |
we provide new insight into immune mechanisms associated with ds that might guide research for the development of new immunotherapeutic agents in this epilepsy syndrome. |
2018-12-11 |
2023-08-13 |
Not clear |
| M Morimoto, S Shimakawa, T Hashimoto, T Kitaoka, S Kyotan. Marked efficacy of combined three-drug therapy (Sodium Valproate, Topiramate and Stiripentol) in a patient with Dravet syndrome. Journal of clinical pharmacy and therapeutics. vol 43. issue 4. 2018-10-15. PMID:29265387. |
dravet syndrome (ds) is an intractable epilepsy syndrome. |
2018-10-15 |
2023-08-13 |
Not clear |
| Anna Tagliabue, Cinzia Ferraris, Francesca Uggeri, Claudia Trentani, Simona Bertoli, Valentina de Giorgis, Pierangelo Veggiotti, Marina Ell. Short-term impact of a classical ketogenic diet on gut microbiota in GLUT1 Deficiency Syndrome: A 3-month prospective observational study. Clinical nutrition ESPEN. vol 17. 2018-06-18. PMID:28361745. |
the classical ketogenic diet (kd) is a high-fat, very low-carbohydrate normocaloric diet used for drug-resistant epilepsy and glucose transporter 1 deficiency syndrome (glut1 ds). |
2018-06-18 |
2023-08-13 |
Not clear |
| Joshua S Kaplan, Nephi Stella, William A Catterall, Ruth E Westenbroe. Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 42. 2018-06-18. PMID:28973916. |
here we show that cannabidiol (cbd) effectively reduced seizures and autistic-like social deficits in a well-validated mouse genetic model of dravet syndrome (ds), a severe childhood epilepsy disorder caused by loss-of-function mutations in the brain voltage-gated sodium channel na |
2018-06-18 |
2023-08-13 |
mouse |
| An-Sofie Schoonjans, Fabienne Marchau, Bernard P Paelinck, Lieven Lagae, Arnold Gammaitoni, Milka Pringsheim, Martin G Keane, Berten Ceuleman. Cardiovascular safety of low-dose fenfluramine in Dravet syndrome: a review of its benefit-risk profile in a new patient population. Current medical research and opinion. vol 33. issue 10. 2018-03-19. PMID:28704161. |
dravet syndrome (ds) is a rare, treatment-resistant epilepsy syndrome for which current treatment regimens are often ineffective. |
2018-03-19 |
2023-08-13 |
Not clear |
| An-Sofie Schoonjans, Fabienne Marchau, Bernard P Paelinck, Lieven Lagae, Arnold Gammaitoni, Milka Pringsheim, Martin G Keane, Berten Ceuleman. Cardiovascular safety of low-dose fenfluramine in Dravet syndrome: a review of its benefit-risk profile in a new patient population. Current medical research and opinion. vol 33. issue 10. 2018-03-19. PMID:28704161. |
fenfluramine is currently in development for treatment of ds, based on reports in the 1980s and 1990s of its anti-epileptic activity in pediatric patients with intractable epilepsy. |
2018-03-19 |
2023-08-13 |
Not clear |
| A Schoonjans, B P Paelinck, F Marchau, B Gunning, A Gammaitoni, B S Galer, L Lagae, B Ceuleman. Low-dose fenfluramine significantly reduces seizure frequency in Dravet syndrome: a prospective study of a new cohort of patients. European journal of neurology. vol 24. issue 2. 2017-12-21. PMID:27790834. |
dravet syndrome (ds) is a severe, drug-resistant epilepsy. |
2017-12-21 |
2023-08-13 |
Not clear |
| Marina Trivisano, Nicola Pietrafusa, Vincenzo di Ciommo, Simona Cappelletti, Luca de Palma, Alessandra Terracciano, Enrico Bertini, Federico Vigevano, Nicola Specchi. PCDH19-related epilepsy and Dravet Syndrome: Face-off between two early-onset epilepsies with fever sensitivity. Epilepsy research. vol 125. 2017-12-18. PMID:27371789. |
aim of this study is to compare pcdh19-related epilepsy and dravet syndrome (ds) in order to find out differences between these two infantile epilepsies with fever sensitivity. |
2017-12-18 |
2023-08-13 |
Not clear |
| Marina Trivisano, Nicola Pietrafusa, Vincenzo di Ciommo, Simona Cappelletti, Luca de Palma, Alessandra Terracciano, Enrico Bertini, Federico Vigevano, Nicola Specchi. PCDH19-related epilepsy and Dravet Syndrome: Face-off between two early-onset epilepsies with fever sensitivity. Epilepsy research. vol 125. 2017-12-18. PMID:27371789. |
we retrospectively reviewed the medical records of 15 patients with pcdh19-related epilepsy and 19 with ds. |
2017-12-18 |
2023-08-13 |
Not clear |
| Marina Trivisano, Nicola Pietrafusa, Vincenzo di Ciommo, Simona Cappelletti, Luca de Palma, Alessandra Terracciano, Enrico Bertini, Federico Vigevano, Nicola Specchi. PCDH19-related epilepsy and Dravet Syndrome: Face-off between two early-onset epilepsies with fever sensitivity. Epilepsy research. vol 125. 2017-12-18. PMID:27371789. |
epilepsy onset was earlier in ds (5.0+2.1 vs 11.2+7.0months; p<0.05). |
2017-12-18 |
2023-08-13 |
Not clear |
| Marina Trivisano, Nicola Pietrafusa, Vincenzo di Ciommo, Simona Cappelletti, Luca de Palma, Alessandra Terracciano, Enrico Bertini, Federico Vigevano, Nicola Specchi. PCDH19-related epilepsy and Dravet Syndrome: Face-off between two early-onset epilepsies with fever sensitivity. Epilepsy research. vol 125. 2017-12-18. PMID:27371789. |
the second seizure/cluster occurred after a longer latency in pcdh19-related epilepsy rather than in ds (10.1±13.6 vs 2.2±2.1months; p<0.05). |
2017-12-18 |
2023-08-13 |
Not clear |
| Marina Trivisano, Nicola Pietrafusa, Vincenzo di Ciommo, Simona Cappelletti, Luca de Palma, Alessandra Terracciano, Enrico Bertini, Federico Vigevano, Nicola Specchi. PCDH19-related epilepsy and Dravet Syndrome: Face-off between two early-onset epilepsies with fever sensitivity. Epilepsy research. vol 125. 2017-12-18. PMID:27371789. |
seizures were mainly single and prolonged seizures in ds, and brief and clustered in pcdh19-related epilepsy. |
2017-12-18 |
2023-08-13 |
Not clear |
| Marina Trivisano, Nicola Pietrafusa, Vincenzo di Ciommo, Simona Cappelletti, Luca de Palma, Alessandra Terracciano, Enrico Bertini, Federico Vigevano, Nicola Specchi. PCDH19-related epilepsy and Dravet Syndrome: Face-off between two early-onset epilepsies with fever sensitivity. Epilepsy research. vol 125. 2017-12-18. PMID:27371789. |
other types of seizures were found in both epilepsies with a prevalence of gtcs and atypical absences in ds, and focal motor and hypomotor seizures in pcdh19-related epilepsy. |
2017-12-18 |
2023-08-13 |
Not clear |
| Geqing Xia, Sarah P Pourali, Timothy A Warner, Chun-Qing Zhang, Robert L Macdonald, Jing-Qiong Kan. Altered GABAA receptor expression in brainstem nuclei and SUDEP in Gabrg2(+/Q390X) mice associated with epileptic encephalopathy. Epilepsy research. vol 123. 2017-12-15. PMID:27131289. |
gabrg2(q390x) is a mutation associated with the epileptic encephalopathy dravet syndrome (ds) and with genetic epilepsy with febrile seizures plus (gefs+) in patients. |
2017-12-15 |
2023-08-13 |
mouse |
| Dora Steel, Joseph D Symonds, Sameer M Zuberi, Andreas Brunklau. Dravet syndrome and its mimics: Beyond SCN1A. Epilepsia. vol 58. issue 11. 2017-11-09. PMID:28880996. |
dravet syndrome (ds) is a severe developmental and epileptic encephalopathy characterized by the onset of prolonged febrile and afebrile seizures in infancy, and evolving to drug-resistant epilepsy with accompanying cognitive, behavioral, and motor impairment. |
2017-11-09 |
2023-08-13 |
Not clear |
| Michael F Hammer, Atsushi Ishii, Laurel Johnstone, Alexander Tchourbanov, Branden Lau, Ryan Sprissler, Brian Hallmark, Miao Zhang, Jin Zhou, Joseph Watkins, Shinichi Hiros. Rare variants of small effect size in neuronal excitability genes influence clinical outcome in Japanese cases of SCN1A truncation-positive Dravet syndrome. PloS one. vol 12. issue 7. 2017-10-06. PMID:28686619. |
dravet syndrome (ds) is a rare, devastating form of childhood epilepsy that is often associated with mutations in the voltage-gated sodium channel gene, scn1a. |
2017-10-06 |
2023-08-13 |
Not clear |
| R E Jiménez-Arredondo, A J L Brambila-Tapia, F M Mercado-Silva, M T Magaña-Torres, L E Figuer. Determination of SCN1A genetic variants in Mexican patients with refractory epilepsy and Dravet syndrome. Genetics and molecular research : GMR. vol 16. issue 2. 2017-09-28. PMID:28525652. |
therefore, the objective of this study was to determine the frequency of scn1a mutations (in the exon 26) in a cohort of mexican patients with ds and refractory epilepsy (re). |
2017-09-28 |
2023-08-13 |
Not clear |
| Taha Gholipour, Sara Mitchell, Rani A Sarkis, Zeina Chemal. The clinical and neurobehavioral course of Down syndrome and dementia with or without new-onset epilepsy. Epilepsy & behavior : E&B. vol 68. 2017-08-09. PMID:28109983. |
adult patients with down syndrome (ds) are at higher risk of developing alzheimer-type dementia and epilepsy. |
2017-08-09 |
2023-08-13 |
Not clear |
| Brian J Dlouhy, Brandon Miller, Anna Jeong, Mary E Bertrand, David D Limbrick, Matthew D Smyt. Palliative epilepsy surgery in Dravet syndrome-case series and review of the literature. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 32. issue 9. 2017-07-13. PMID:27465677. |
dravet syndrome (ds), also known as severe myoclonic epilepsy of infancy (smei), is a rare genetic disorder that results in severe childhood-onset epilepsy. |
2017-07-13 |
2023-08-13 |
Not clear |