| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenxu Zhou, Anjan Debnath, Gareth Jennings, Hye Jee Hahn, Boden H Vanderloop, Minu Chaudhuri, W David Nes, Larissa M Podus. Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. PLoS pathogens. vol 14. issue 9. 2019-01-22. PMID:30212566. |
naegleria fowleri is a free-living amoeba that can also act as an opportunistic pathogen causing severe brain infection, primary amebic meningoencephalitis (pam), in humans. |
2019-01-22 |
2023-08-13 |
human |
| Ling-Ling Zhang, Mao Wu, Bang-Chuan Hu, Hua-Liang Chen, Jin-Ren Pan, Wei Ruan, Li-Nong Ya. Identification and molecular typing of Naegleria fowleri from a patient with primary amebic meningoencephalitis in China. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. vol 72. 2018-11-13. PMID:29751112. |
known to cause an acute, fulminant, and rapidly fatal central nervous system infection in humans called primary amebic meningoencephalitis (pam). |
2018-11-13 |
2023-08-13 |
Not clear |
| Nicole Liechti, Nadia Schürch, Rémy Bruggmann, Matthias Wittwe. The genome of Naegleria lovaniensis, the basis for a comparative approach to unravel pathogenicity factors of the human pathogenic amoeba N. fowleri. BMC genomics. vol 19. issue 1. 2018-11-12. PMID:30185166. |
more than 40 species have been characterized, but only naegleria fowleri (n. fowleri) is known as a human pathogen causing primary amoebic meningoencephalitis (pam), a fast progressing and mostly fatal disease of the central nervous system. |
2018-11-12 |
2023-08-13 |
human |
| Jia Xue, Frederica G Lamar, Bowen Zhang, Siyu Lin, Jennifer G Lamori, Samendra P Shercha. Quantitative assessment of Naegleria fowleri and fecal indicator bacteria in brackish water of Lake Pontchartrain, Louisiana. The Science of the total environment. vol 622-623. 2018-10-09. PMID:29220778. |
brackish water samples from lake pontchartrain in louisiana were assessed for the presence of pathogenic amoeba naegleria fowleri, which causes primary amoebic meningoencephalitis (pam). |
2018-10-09 |
2023-08-13 |
Not clear |
| Charlton Lam, Melissa Jamerson, Guy Cabral, Ana Maris Carlesso, Francine Marciano-Cabra. Expression of matrix metalloproteinases in Naegleria fowleri and their role in invasion of the central nervous system. Microbiology (Reading, England). vol 163. issue 10. 2018-05-23. PMID:28954644. |
naegleria fowleri is a free-living amoeba found in freshwater lakes and ponds and is the causative agent of primary amoebic meningoencephalitis (pam), a rapidly fatal disease of the central nervous system (cns). |
2018-05-23 |
2023-08-13 |
Not clear |
| Magdalena Dzikowiec, Katarzyna Góralska, Joanna Błaszkowsk. Neuroinvasions caused by parasites Annals of parasitology. vol 63. issue 4. 2018-05-07. PMID:29385325. |
some parasitic infections of the brain are lethal if left untreated (e.g., cerebral malaria – plasmodium falciparum, primary amoebic meningoencephalitis (pam) – naegleria fowleri, baylisascariosis – baylisascaris procyonis, african sleeping sickness – african trypanosomes). |
2018-05-07 |
2023-08-13 |
human |
| Ingrid Zyserman, Deboprosad Mondal, Francisco Sarabia, James H McKerrow, William R Roush, Anjan Debnat. Identification of cysteine protease inhibitors as new drug leads against Naegleria fowleri. Experimental parasitology. vol 188. 2018-05-04. PMID:29551628. |
primary amebic meningoencephalitis (pam) is a rapidly fatal infection caused by the free-living ameba naegleria fowleri. |
2018-05-04 |
2023-08-13 |
Not clear |
| Natália Karla Bellini, Thomás Michelena Santos, Marco Túlio Alves da Silva, Otavio Henrique Thieman. The therapeutic strategies against Naegleria fowleri. Experimental parasitology. vol 187. 2018-04-18. PMID:29501696. |
naegleria fowleri is a pathogenic amoeboflagellate most prominently known for its role as the etiological agent of the primary amoebic meningoencephalitis (pam), a disease that afflicts the central nervous system and is fatal in more than 95% of the reported cases. |
2018-04-18 |
2023-08-13 |
Not clear |
| Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podus. CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). PLoS neglected tropical diseases. vol 11. issue 12. 2018-01-30. PMID:29284029. |
cyp51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (pam). |
2018-01-30 |
2023-08-13 |
Not clear |
| Anjan Debnath, Claudia M Calvet, Gareth Jennings, Wenxu Zhou, Alexander Aksenov, Madeline R Luth, Ruben Abagyan, W David Nes, James H McKerrow, Larissa M Podus. CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM). PLoS neglected tropical diseases. vol 11. issue 12. 2018-01-30. PMID:29284029. |
primary amoebic meningoencephalitis (pam) is caused by naegleria fowleri, a free-living amoeba that occasionally infects humans. |
2018-01-30 |
2023-08-13 |
Not clear |
| María Reyes-Batlle, Carolina Wagner, Atteneri López-Arencibia, Ines Sifaoui, Enrique Martínez-Carretero, Basilio Valladares, Jose E Piñero, Jacob Lorenzo-Morale. Isolation and molecular characterization of a Naegleria strain from a recreational water fountain in Tenerife, Canary Islands, Spain. Acta parasitologica. vol 62. issue 2. 2017-12-20. PMID:28426408. |
naegleria fowleri is a pathogenic fla species which causes primary amoebic meningoencephalitis (pam). |
2017-12-20 |
2023-08-13 |
Not clear |
| M Montalbano Di Filippo, A Novelletto, D Di Cave, F Berrill. Identification and phylogenetic position of Naegleria spp. from geothermal springs in Italy. Experimental parasitology. vol 183. 2017-12-18. PMID:28811103. |
among the recognized species, naegleria fowleri causes primary amoebic meningoencephalitis (pam), while two other species, naegleria australiensis and naegleria italica, have been reported as pathogenic in experimental animals. |
2017-12-18 |
2023-08-13 |
Not clear |
| Gi-Sang Seong, Hae-Jin Sohn, Heekyoung Kang, Ga-Eun Seo, Jong-Hyun Kim, Ho-Joon Shi. Production and characterization of monoclonal antibodies against cathepsin B and cathepsin B-Like proteins of Naegleria fowleri. Experimental parasitology. vol 183. 2017-12-18. PMID:28919331. |
naegleria fowleri causes fatal primary amoebic meningoencephalitis (pam) in humans and experimental animals. |
2017-12-18 |
2023-08-13 |
Not clear |
| Abdul Mannan Bai. Primary Amoebic Meningoencephalitis: Neurochemotaxis and Neurotropic Preferences of Naegleria fowleri. ACS chemical neuroscience. vol 7. issue 8. 2017-10-30. PMID:27447543. |
the infection caused by this free-living amoeba is universally fatal within a week of onset of the signs and symptoms of the disease called primary amoebic meningoencephalitis (pam). |
2017-10-30 |
2023-08-13 |
Not clear |
| Mashina Chomba, Luchenga A Mucheleng'anga, Sombo Fwoloshi, Joseph Ngulube, Mable M Muteng. A case report: primary amoebic meningoencephalitis in a young Zambian adult. BMC infectious diseases. vol 17. issue 1. 2017-10-30. PMID:28764655. |
primary amoebic meningoencephalitis (pam) is a fulminant disease of the brain caused by naegleria fowleri. |
2017-10-30 |
2023-08-13 |
Not clear |
| J Jeffrey Pugh, Rebecca A Lev. Naegleria fowleri: Diagnosis, Pathophysiology of Brain Inflammation, and Antimicrobial Treatments. ACS chemical neuroscience. vol 7. issue 9. 2017-10-27. PMID:27525348. |
primary amoebic meningoencephalitis (pam) is a very rare disease with a high mortality rate. |
2017-10-27 |
2023-08-13 |
Not clear |
| Linda G Capewell, Aaron M Harris, Jonathan S Yoder, Jennifer R Cope, Brittany A Eddy, Sharon L Roy, Govinda S Visvesvara, LeAnne M Fox, Michael J Beac. Diagnosis, Clinical Course, and Treatment of Primary Amoebic Meningoencephalitis in the United States, 1937-2013. Journal of the Pediatric Infectious Diseases Society. vol 4. issue 4. 2017-10-25. PMID:26582886. |
primary amoebic meningoencephalitis (pam) is a rapidly progressing waterborne illness that predominately affects children and is nearly always fatal. |
2017-10-25 |
2023-08-13 |
Not clear |
| Jinyoung Lee, Jung-Mi Kang, Tae Im Kim, Jong-Hyun Kim, Hae-Jin Sohn, Byoung-Kuk Na, Ho-Joon Shi. Excretory and Secretory Proteins of Naegleria fowleri Induce Inflammatory Responses in BV-2 Microglial Cells. The Journal of eukaryotic microbiology. vol 64. issue 2. 2017-09-26. PMID:27480446. |
naegleria fowleri, a free-living amoeba that is found in diverse environmental habitats, can cause a type of fulminating hemorrhagic meningoencephalitis, primary amoebic meningoencephalitis (pam), in humans. |
2017-09-26 |
2023-08-13 |
Not clear |
| A Contis-Montes de Oca, M Carrasco-Yépez, R Campos-Rodríguez, J Pacheco-Yépez, P Bonilla-Lemus, J Pérez-López, S Rojas-Hernánde. Neutrophils extracellular traps damage Naegleria fowleri trophozoites opsonized with human IgG. Parasite immunology. vol 38. issue 8. 2017-09-07. PMID:27189133. |
naegleria fowleri infects humans through the nasal mucosa causing a disease in the central nervous system known as primary amoebic meningoencephalitis (pam). |
2017-09-07 |
2023-08-13 |
human |
| Zhihao Yu, Haylea C Miller, Geoffrey J Puzon, Brian H Clower. Development of Untargeted Metabolomics Methods for the Rapid Detection of Pathogenic Naegleria fowleri. Environmental science & technology. vol 51. issue 8. 2017-06-08. PMID:28290675. |
despite comparatively low levels of infection, primary amoebic meningoencephalitis (pam) induced by naegleria fowleri is extremely lethal, with mortality rates above 95%. |
2017-06-08 |
2023-08-13 |
Not clear |