| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reham Shehabeldin, David Lutz, Meliha Karsak, Michael Frotscher, Kerstin Krieglstein, Ahmed Shara. Reelin controls the positioning of brainstem serotonergic raphe neurons. PloS one. vol 13. issue 7. 2019-01-02. PMID:30001399. |
our results open the window for further studies on the interaction of reelin and serotonin and the pathogenesis of neurodevelopmental disorders. |
2019-01-02 |
2023-08-13 |
Not clear |
| Sorayya Kheirouri, Parinaz Kalejahi, Seyyed Gholamreza Nooraza. Plasma levels of serotonin, gastrointestinal symptoms,and sleep problems in children with autism. Turkish journal of medical sciences. vol 46. issue 6. 2018-09-20. PMID:28081325. |
autism is a neurodevelopmental disorder identified with higher frequency of serotonin abnormalities and gastrointestinal (gi) and sleep problems. |
2018-09-20 |
2023-08-13 |
Not clear |
| Krystyna Szymańska, Katarzyna Kuśmierska, Maria Nowacka, Jolanta Sykut-Cegielska, Urszula Demko. Phenotypic features of children with neurodevelopmental diseases in relation to biogenic amines. Respiratory physiology & neurobiology. vol 209. 2015-12-07. PMID:25514185. |
we aimed to correlate clinical phenotypes of 55 children with neurodevelopmental disorders with dopamine (hva) and serotonin (5-hiia) metabolites in csf. |
2015-12-07 |
2023-08-13 |
Not clear |
| Katsumasa Muneoka, Makiko Kuwagata, Tetsuo Ogawa, Seiji Shiod. Mother/offspring co-administration of the traditional herbal remedy yokukansan during the nursing period influences grooming and cerebellar serotonin levels in a rat model of neurodevelopmental disorders. Cerebellum (London, England). vol 14. issue 2. 2015-12-01. PMID:25315739. |
mother/offspring co-administration of the traditional herbal remedy yokukansan during the nursing period influences grooming and cerebellar serotonin levels in a rat model of neurodevelopmental disorders. |
2015-12-01 |
2023-08-13 |
rat |
| Valentina Mosienko, Daniel Beis, Natalia Alenina, Markus Wöh. Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin. Molecular autism. vol 6. 2015-04-22. PMID:25901271. |
several lines of evidence associate altered 5-ht signaling with psychopathology in humans, particularly neurodevelopmental disorders such as autism spectrum disorders (asd). |
2015-04-22 |
2023-08-13 |
mouse |
| S Migliarini, G Pacini, B Pelosi, G Lunardi, M Pasqualett. Lack of brain serotonin affects postnatal development and serotonergic neuronal circuitry formation. Molecular psychiatry. vol 18. issue 10. 2014-05-29. PMID:23007167. |
on the whole, these findings reveal that alterations of serotonin levels during cns development affect the proper wiring of the brain that may produce long-lasting changes leading to neurodevelopmental disorders. |
2014-05-29 |
2023-08-12 |
mouse |
| Simon Trent, Rachel Dean, Bonnie Veit, Tommaso Cassano, Gaurav Bedse, Obah A Ojarikre, Trevor Humby, William Davie. Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology. vol 38. issue 8. 2014-01-31. PMID:23276394. |
although sts/asmt deficiency did not influence foraging behaviour, reactivity to familiar objects in novel locations, or 'ability to wait', it did result in markedly increased response rates; these rates correlated with hippocampal 5-ht levels and are likely to index behavioural perseveration, a frequent feature of neurodevelopmental disorders. |
2014-01-31 |
2023-08-12 |
mouse |
| Josefine S Witteveen, Anthonieke Middelman, Josephus A van Hulten, Gerard J M Martens, Judith R Homberg, Sharon M Kol. Lack of serotonin reuptake during brain development alters rostral raphe-prefrontal network formation. Frontiers in cellular neuroscience. vol 7. 2013-10-10. PMID:24109430. |
one of the targets of the 5-ht projection system, originating in the brainstem raphe nuclei, is the medial prefrontal cortex (mpfc), an area involved in higher cognitive functions and important in the etiology of many neurodevelopmental disorders. |
2013-10-10 |
2023-08-12 |
rat |
| Josefine S Witteveen, Anthonieke Middelman, Josephus A van Hulten, Gerard J M Martens, Judith R Homberg, Sharon M Kol. Lack of serotonin reuptake during brain development alters rostral raphe-prefrontal network formation. Frontiers in cellular neuroscience. vol 7. 2013-10-10. PMID:24109430. |
the tremendous complexity of the 5-ht projection system and its role in several neurodevelopmental disorders highlights the need for further research in this largely unexplored area. |
2013-10-10 |
2023-08-12 |
rat |
| Mareen Engel, Marten P Smidt, Johannes A van Hoof. The serotonin 5-HT3 receptor: a novel neurodevelopmental target. Frontiers in cellular neuroscience. vol 7. 2013-06-14. PMID:23761731. |
taken together, the 5-ht3 receptor emerges as a potential key-regulator of network formation and function in the cns, which could have a major impact on our understanding of neurodevelopmental disorders in which 5-ht plays a role. |
2013-06-14 |
2023-08-12 |
Not clear |
| Junlin Zhang, Katie A Dennis, Ryan D Darling, Loai Alzghoul, Ian A Paul, Kimberly L Simpson, Rick C S Li. Neonatal citalopram exposure decreases serotonergic fiber density in the olfactory bulb of male but not female adult rats. Frontiers in cellular neuroscience. vol 7. 2013-05-16. PMID:23675318. |
because dysfunction of the early 5ht system has been implicated in the etiology of neurodevelopmental disorders such as autism spectrum disorders (asds), these new findings may offer insight into the abnormal olfactory perception often noted in patients with asd. |
2013-05-16 |
2023-08-12 |
rat |
| Shi-Sheng Zhou, Yi-Ming Zhou, Da Li, Qiang M. Early infant exposure to excess multivitamin: a risk factor for autism? Autism research and treatment. vol 2013. 2013-03-28. PMID:23533752. |
autism, a neurodevelopmental disorder that affects boys more than girls, is often associated with altered levels of monoamines (serotonin and catecholamines), especially elevated serotonin levels. |
2013-03-28 |
2023-08-12 |
Not clear |
| Klaus-Peter Lesch, Jonas Waide. Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders. Neuron. vol 76. issue 1. 2012-12-10. PMID:23040814. |
serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders. |
2012-12-10 |
2023-08-12 |
Not clear |
| Klaus-Peter Lesch, Jonas Waide. Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders. Neuron. vol 76. issue 1. 2012-12-10. PMID:23040814. |
in this review, we discuss emerging concepts as to how defects in synaptic plasticity impact our biosocial brain and how recent findings regarding 5-ht's role in brain development and function provide insight into the cellular and physiological basis of neurodevelopmental disorders. |
2012-12-10 |
2023-08-12 |
Not clear |
| Klaus-Peter Lesch, Naozumi Araragi, Jonas Waider, Daniel van den Hove, Lise Gutknech. Targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 367. issue 1601. 2012-12-06. PMID:22826343. |
targeting brain serotonin synthesis: insights into neurodevelopmental disorders with long-term outcomes related to negative emotionality, aggression and antisocial behaviour. |
2012-12-06 |
2023-08-12 |
mouse |
| Dubravka Hranilovic, Sofia Blazevic, Nedjeljka Ivica, Lipa Cicin-Sain, Darko Oreskovi. The effects of the perinatal treatment with 5-hydroxytryptophan or tranylcypromine on the peripheral and central serotonin homeostasis in adult rats. Neurochemistry international. vol 59. issue 2. 2011-11-22. PMID:21672593. |
autism is a neurodevelopmental disorder in which 5ht homeostasis is disturbed both centrally and peripherally, but the relationship between the 5ht disturbances in the two compartments is not understood. |
2011-11-22 |
2023-08-12 |
rat |
| Ryan T Strachan, John A Allen, Douglas J Sheffler, Bryan L Rot. p90 Ribosomal S6 kinase 2, a novel GPCR kinase, is required for growth factor-mediated attenuation of GPCR signaling. Biochemistry. vol 49. issue 12. 2010-04-23. PMID:20136148. |
given the pervasiveness of growth factor signaling, this novel regulatory mechanism has the potential to explain how 5-ht(2a) receptors are regulated in vivo, with potential implications for human diseases in which 5-ht(2a) or rtk activity is altered (e.g., neuropsychiatric and neurodevelopmental disorders). |
2010-04-23 |
2023-08-12 |
mouse |
| Christi J Wylie, Timothy J Hendricks, Bing Zhang, Lily Wang, Pengcheng Lu, Patrick Leahy, Stephanie Fox, Hiroshi Maeno, Evan S Deneri. Distinct transcriptomes define rostral and caudal serotonin neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 2. 2010-02-01. PMID:20071532. |
furthermore, we identified several hundred transcripts encoding homeodomain, axon guidance, cell adhesion, intracellular signaling, ion transport, and imprinted genes associated with various neurodevelopmental disorders that were differentially enriched in developing rostral and caudal 5ht neurons. |
2010-02-01 |
2023-08-12 |
Not clear |
| Ludmila A Vataeva, Vladimir S Kudrin, Elena A Vershinina, Vjacheslav M Mosin, Ekaterina I Tiul'kova, Vladimir A Otelli. Maternal para-chlorophenylalanine exposure modifies central monoamines and behaviors in the adult offspring. Brain research. vol 1234. 2008-12-08. PMID:18718452. |
we reported a perspective animal model of neurodevelopmental disorders using rats prenatally exposed to an inhibitor of serotonin (5ht) synthesis, para-chlorophenylalanine (pcpa). |
2008-12-08 |
2023-08-12 |
rat |
| Thomas H Wassink, Heather C Hazlett, Eric A Epping, Stephan Arndt, Stephen R Dager, Gerard D Schellenberg, Geraldine Dawson, Joseph Pive. Cerebral cortical gray matter overgrowth and functional variation of the serotonin transporter gene in autism. Archives of general psychiatry. vol 64. issue 6. 2007-07-03. PMID:17548752. |
autism is a heritable neurodevelopmental disorder characterized biologically by enlargement of the head and brain and abnormalities of serotonin neurotransmission. |
2007-07-03 |
2023-08-12 |
Not clear |