Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J L Wile. Behavioral pharmacology of N-methyl-D-aspartate antagonists: implications for the study and pharmacotherapy of anxiety and schizophrenia. Experimental and clinical psychopharmacology. vol 5. issue 4. 1998-01-09. PMID:9386963. |
in addition, this type of study may result in development of screening procedures for atypical antipsychotics useful in the treatment of schizophrenia resistant to pharmacotherapy with traditional antipsychotics. |
1998-01-09 |
2023-08-12 |
Not clear |
O Gosselin, J M Ribeyre, J P Kah. [Atypical pharmacologic characteristics of an antipsychotic drug: clozapine]. L'Encephale. vol 23 Spec No 4. 1997-12-30. PMID:9417400. |
the discovery of clozapine in the mid-sixties and the demonstration of its clinical efficacy vis-à-vis recalcitrant schizophrenia contributed to the development of specific psychopharmacological research addressing the concept of atypical antipsychotics. |
1997-12-30 |
2023-08-12 |
Not clear |
S M Stah. "Awakening" from schizophrenia: intramolecular polypharmacy and the atypical antipsychotics. The Journal of clinical psychiatry. vol 58. issue 9. 1997-11-07. PMID:9378687. |
"awakening" from schizophrenia: intramolecular polypharmacy and the atypical antipsychotics. |
1997-11-07 |
2023-08-12 |
Not clear |
W M Glaze. Olanzapine and the new generation of antipsychotic agents: patterns of use. The Journal of clinical psychiatry. vol 58 Suppl 10. 1997-08-27. PMID:9265912. |
this article will describe the potential use of the atypical antipsychotics, especially olanzapine, for affective mood disturbances in schizophrenia, psychotic depression and mania, first-break schizophrenia, comorbid schizophrenia and substance abuse disorders, dementia in the elderly and those with late-onset schizophrenia, and behavioral problems in patients with mental retardation or developmental delays. |
1997-08-27 |
2023-08-12 |
Not clear |
A Meyer-Lindenberg, H Gruppe, U Bauer, S Lis, S Krieger, B Gallhofe. Improvement of cognitive function in schizophrenic patients receiving clozapine or zotepine: results from a double-blind study. Pharmacopsychiatry. vol 30. issue 2. 1997-07-01. PMID:9131723. |
clinical interest in the so-called atypical antipsychotics currently focuses on the possibility of improving the negative symptoms of schizophrenia and the cognitive dysfunction associated with the disease. |
1997-07-01 |
2023-08-12 |
Not clear |
G F Busatto, R W Kerwi. Perspectives on the role of serotonergic mechanisms in the pharmacology of schizophrenia. Journal of psychopharmacology (Oxford, England). vol 11. issue 1. 1997-06-19. PMID:9097883. |
in addition, molecular biological studies have suggested that allelic variations of 5-ht receptor genes may affect both susceptibility to schizophrenia and clinical response to atypical antipsychotics. |
1997-06-19 |
2023-08-12 |
Not clear |
B Fulton, K L Go. Olanzapine. A review of its pharmacological properties and therapeutic efficacy in the management of schizophrenia and related psychoses. Drugs. vol 53. issue 2. 1997-04-10. PMID:9028746. |
its efficacy in refractory schizophrenia and its place relative to other atypical antipsychotics remain to be determined. |
1997-04-10 |
2023-08-12 |
Not clear |
J W Olney, N B Farbe. Efficacy of clozapine compared with other antipsychotics in preventing NMDA-antagonist neurotoxicity. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961572. |
by studying mechanisms by which clozapine prevents the nan reaction in rats, we hope to gain insight into mechanisms by which clozapine or other atypical antipsychotics ameliorate symptoms in schizophrenia. |
1994-11-28 |
2023-08-12 |
rat |
L Ereshefsky, T K Tran-Johnson, M D Watanab. Pathophysiologic basis for schizophrenia and the efficacy of antipsychotics. Clinical pharmacy. vol 9. issue 9. 1990-12-04. PMID:1977544. |
new investigative techniques and the study of atypical antipsychotics suggest that a dysregulation hypothesis may be more consistent with the complexities of schizophrenia. |
1990-12-04 |
2023-08-11 |
Not clear |