| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maxim Krikov, Christa Thone-Reineke, Susanne Müller, Arno Villringer, Thomas Unge. Candesartan but not ramipril pretreatment improves outcome after stroke and stimulates neurotrophin BNDF/TrkB system in rats. Journal of hypertension. vol 26. issue 3. 2008-04-24. PMID:18300867. |
drugs interfering with the renin-angiotensin system (ras) have been shown to reduce the incidence of stroke in patients at risk and to afford neuroprotection in experimental brain ischemia. |
2008-04-24 |
2023-08-12 |
rat |
| A Adunsky, M Hershkowit. Binding of platelet-activating factor to platelets of ischemic stroke patients. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 53. issue 4. 2008-04-10. PMID:18314562. |
platelet-activating factor (paf) has been suggested to play an important role in brain ischemia and stroke. |
2008-04-10 |
2023-08-12 |
human |
| Masaki Mogi, Masaru Iwai, Rui Chen, Jun Iwanami, Ayumi Ide, Kana Tsukuda, Toyofumi Yoshii, Masatsugu Horiuch. Amlodipine treatment reduces stroke size in apolipoprotein E-deficient mice. American journal of hypertension. vol 19. issue 11. 2007-01-30. PMID:17070425. |
this study investigated the effects of amlodipine, an l-type calcium channel blocker, on stroke size after focal brain ischemia in apolipoprotein e-deficient (apoe ko) mice. |
2007-01-30 |
2023-08-12 |
mouse |
| Marie Csete, Luis Rodriguez, Melissa Wilcox, Seetharam Chadalavad. Erythropoietin receptor is expressed on adult rat dopaminergic neurons and erythropoietin is neurotrophic in cultured dopaminergic neuroblasts. Neuroscience letters. vol 359. issue 1-2. 2004-05-21. PMID:15050726. |
exogenous erythropoietin (epo) is a potent neurotrophic factor in vivo, protective against neuronal death in animal models of brain ischemia and human stroke. |
2004-05-21 |
2023-08-12 |
human |
| Noriko Hagiwara, Kazunori Toyoda, Shigeru Fujimoto, Yasushi Okad. Extensive bihemispheric ischemia caused by acute occlusion of three major arteries to the brain. Journal of the neurological sciences. vol 212. issue 1-2. 2003-08-14. PMID:12810006. |
diffusion-weighted magnetic resonance imaging (mri) delineated brain ischemia in the whole bilateral cerebral hemisphere soon after the stroke onset. |
2003-08-14 |
2023-08-12 |
Not clear |
| F Mauler, T Fahrig, E Horváth, R Jor. Inhibition of evoked glutamate release by the neuroprotective 5-HT(1A) receptor agonist BAY x 3702 in vitro and in vivo. Brain research. vol 888. issue 1. 2001-03-01. PMID:11146061. |
brain ischemia provoked by stroke or traumatic brain injury induces a massive increase in neurotransmitter release, in particular of the excitotoxin glutamate. |
2001-03-01 |
2023-08-12 |
rat |
| M König, R Banach-Planchamp, M Kraus, E Klotz, A Falk, W Gehlen, L Heuse. [CT perfusion imaging in acute ischemic cerebral infarct: comparison of cerebral perfusion maps and conventional CT findings]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. vol 172. issue 3. 2000-05-05. PMID:10778451. |
to evaluate the findings of acute brain ischemia on different functional maps of cerebral perfusion ct in stroke patients and to compare the results with early ischemic changes on conventional ct. |
2000-05-05 |
2023-08-12 |
Not clear |
| M F Gaskill-Shiple. Routine CT evaluation of acute stroke. Neuroimaging clinics of North America. vol 9. issue 3. 1999-11-04. PMID:10433635. |
although new imaging techniques such as mr perfusion/diffusion and xenon ct have shown considerable promise in the detection of early brain ischemia, noncontrast ct remains the primary imaging test for the evaluation of acute stroke. |
1999-11-04 |
2023-08-12 |
Not clear |
| M J Brosnan, J S Clark, B Jeffs, C D Negrin, P Van Vooren, S M Arribas, H Carswell, T J Aitman, C Szpirer, I M Macrae, A F Dominicza. Genes encoding atrial and brain natriuretic peptides as candidates for sensitivity to brain ischemia in stroke-prone hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 33. issue 1 Pt 2. 1999-02-26. PMID:9931119. |
-previous studies suggested that atrial natriuretic peptide gene (anp) and brain natriuretic peptide gene (bnp) are plausible candidate genes for susceptibility to stroke and for sensitivity to brain ischemia in the stroke-prone spontaneously hypertensive rat (shrsp). |
1999-02-26 |
2023-08-12 |
rat |
| T Zheng, W Li, A Zhang, B T Altura, B M Altur. Alpha-tocopherol prevents ethanol-induced elevation of [Ca2+]i in cultured canine cerebral vascular smooth muscle cells. Neuroscience letters. vol 245. issue 1. 1998-07-14. PMID:9596345. |
these results suggest that alcohol-induced lipid peroxidation of cerebral vascular muscle cell membranes triggers membrane entry of extracellular ca2+, which could play an important role in ethanol-induced cerebrovasospasm, brain ischemia and stroke. |
1998-07-14 |
2023-08-12 |
Not clear |
| H Kageyama, K Nemoto, F Nemoto, M Sekimoto, Y Nara, T Nabika, Y Iwayama, K Fukamachi, I Tomita, E Senba, C J Forehand, E D Hendley, T Ueyam. Mutation of the trkB gene encoding the high-affinity receptor for brain-derived neurotrophic factor in stroke-prone spontaneously hypertensive rats. Biochemical and biophysical research communications. vol 229. issue 3. 1997-01-30. PMID:8954962. |
brain-derived neurotrophic factor and its receptor, trkb, are thought to play a crucial role for protection against neuronal death induced by brain ischemia, such as in stroke. |
1997-01-30 |
2023-08-12 |
rat |
| D Le Biha. [Diffusion, perfusion and functional magnetic resonance imaging]. Journal des maladies vasculaires. vol 20. issue 3. 1996-02-13. PMID:8543902. |
diffusion mri is also the only imaging modality which shows brain ischemia at a very early stage, even before t1w or t2w mr images become abnormal, offering great promises in the management of stroke patients. |
1996-02-13 |
2023-08-12 |
Not clear |
| S Smirne, M Franceschi, G Truci, M Camerlingo, R Pirola, L Ferini-Strambi, S R Baregg. Homovanillic acid and 5-hydroxyindoleacetic acid modifications in CSF of patients with stroke and multi-infarct dementia. Stroke. vol 16. issue 6. 1986-02-21. PMID:2418548. |
our results in stroke can be interpreted as showing they are the consequence of dopamine and serotonin global depletion in the early phases of brain ischemia. |
1986-02-21 |
2023-08-11 |
human |