| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tamara A Hafiz, Sarah S Aldharman, Ruby N AlSubaie, Lena D Alzahrani, Ibrahim Ahmed J Albalawi, Yara A Alali, Maisaa M Yousuf, Hayat M Alharbi, Nawaf S Alamri, Syed F Jami. Blood Transfusion Vs. Hydroxyurea for Stroke Prevention in Children With Sickle Cell Anemia: A Systematic Review and Meta-Analysis. Cureus. vol 14. issue 11. 2022-12-26. PMID:36569706. |
blood transfusion and hydroxyurea (hu) therapy are used to prevent stroke in children with sickle cell disease (scd). |
2022-12-26 |
2023-08-14 |
human |
| Deepa Manwani, Arthur L Burnett, Jincy Paulose, Glorian P Yen, Tanya Burton, Amy Anderson, Sara Wang, Soyon Lee, Santosh L Sara. Treatment patterns and burden of complications associated with sickle cell disease: A US retrospective claims analysis. EJHaem. vol 3. issue 4. 2022-12-05. PMID:36467832. |
scd complications occurred frequently; in the overall population, the highest follow-up incidences per 1000 person-years were for acute kidney injury (53.1), chronic kidney disease (40.6), and stroke (39.0). |
2022-12-05 |
2023-08-14 |
Not clear |
| Tonner DeBeer, Lori C Jordan, Spencer Waddle, Chelsea Lee, Niral J Patel, Maria Garza, L Taylor Davis, Sumit Pruthi, Sky Jones, Manus J Donahu. Red cell exchange transfusions increase cerebral capillary transit times and may alter oxygen extraction in sickle cell disease. NMR in biomedicine. 2022-12-05. PMID:36468659. |
persons with sickle cell disease (scd) suffer from chronic hemolytic anemia, reduced blood oxygen content, and lifelong risk of silent and overt stroke. |
2022-12-05 |
2023-08-14 |
Not clear |
| Tonner DeBeer, Lori C Jordan, Spencer Waddle, Chelsea Lee, Niral J Patel, Maria Garza, L Taylor Davis, Sumit Pruthi, Sky Jones, Manus J Donahu. Red cell exchange transfusions increase cerebral capillary transit times and may alter oxygen extraction in sickle cell disease. NMR in biomedicine. 2022-12-05. PMID:36468659. |
major conventional stroke risk factors are absent in most individuals with scd, yet nearly 50% have evidence of brain infarcts by age 30 years, indicating alternative etiologies for ischemia. |
2022-12-05 |
2023-08-14 |
Not clear |
| Maria Aline Ferreira de Cerqueira, Luciana Maria Fortes Magalhães Castelo Branco Couto, Mírian Perpétua Palha Dias Parente, Juan Clinton Lleren. Sickle-Cell Disease and Stroke: Quality of Life of Patients in a Chronic Transfusion Regimen from the Caregivers' Perspective. Pediatric hematology and oncology. 2022-11-24. PMID:36420998. |
strokes affect up to 10% of children with sickle-cell disease (scd). |
2022-11-24 |
2023-08-14 |
Not clear |
| Maria Aline Ferreira de Cerqueira, Luciana Maria Fortes Magalhães Castelo Branco Couto, Mírian Perpétua Palha Dias Parente, Juan Clinton Lleren. Sickle-Cell Disease and Stroke: Quality of Life of Patients in a Chronic Transfusion Regimen from the Caregivers' Perspective. Pediatric hematology and oncology. 2022-11-24. PMID:36420998. |
this article aims to evaluate the quality of life (qol) of children and adolescents with scd undergoing a chronic transfusion regimen (ctr) for stroke prophylaxis, according to their caregivers' perception. |
2022-11-24 |
2023-08-14 |
Not clear |
| Maria Aline Ferreira de Cerqueira, Luciana Maria Fortes Magalhães Castelo Branco Couto, Mírian Perpétua Palha Dias Parente, Juan Clinton Lleren. Sickle-Cell Disease and Stroke: Quality of Life of Patients in a Chronic Transfusion Regimen from the Caregivers' Perspective. Pediatric hematology and oncology. 2022-11-24. PMID:36420998. |
it is possible that the occurrence of a stroke enhances the caregivers' negative perceptions about the qol of patients with scd. |
2022-11-24 |
2023-08-14 |
Not clear |
| Kristie Ramos, Kristin P Guilliams, Melanie E Field. The Development of Neuroimaging Biomarkers for Cognitive Decline in Sickle Cell Disease. Hematology/oncology clinics of North America. vol 36. issue 6. 2022-11-18. PMID:36400537. |
transcranial doppler ultrasound and structural brain mri are currently used for primary and secondary stroke prevention, but laboratory or imaging biomarkers do not currently exist that are specific to the risk of cognitive dysfunction in patients with scd. |
2022-11-18 |
2023-08-14 |
Not clear |
| Françoise Bernaudin, Cécile Arnaud, Annie Kamdem, Isabelle Hau, Fouad Madhi, Camille Jung, Ralph Epaud, Suzanne Verlha. Incidence, kinetics, and risk factors for intra- and extracranial cerebral arteriopathies in a newborn sickle cell disease cohort early assessed by transcranial and cervical color Doppler ultrasound. Frontiers in neurology. vol 13. 2022-10-03. PMID:36188389. |
the risk of stroke in children with sickle cell disease (scd) is detected by abnormal intracranial arterial time-averaged mean of maximum velocities (tamvs ≥200 cm/s). |
2022-10-03 |
2023-08-14 |
Not clear |
| Laura A Schieve, Gretchen M Simmons, Amanda B Payne, Karon Abe, Lewis L Hsu, Mary Hulihan, Shammara Pope, Sarah Rhie, Brandi Dupervil, W Craig Hoope. Vital Signs: Use of Recommended Health Care Measures to Prevent Selected Complications of Sickle Cell Anemia in Children and Adolescents - Selected U.S. States, 2019. MMWR. Morbidity and mortality weekly report. vol 71. issue 39. 2022-09-29. PMID:36173745. |
in 2014, an expert panel convened by the national heart, lung, and blood institute issued recommendations to prevent or reduce complications in children and adolescents with the most severe scd subtypes, known as sickle cell anemia (sca); recommendations included 1) annual screening of children and adolescents aged 2-16 years with transcranial doppler (tcd) ultrasound to identify those at risk for stroke and 2) offering hydroxyurea therapy to children and adolescents aged ≥9 months to reduce the risk for several life-threatening complications. |
2022-09-29 |
2023-08-14 |
Not clear |
| Ava Runge, Danielle Brazel, Zahra Pakba. Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences. vol 442. 2022-09-23. PMID:36150233. |
this review highlights the burden of cerebrovascular disease in scd, including both stroke and silent cerebral infarct (sci). |
2022-09-23 |
2023-08-14 |
Not clear |
| Ava Runge, Danielle Brazel, Zahra Pakba. Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences. vol 442. 2022-09-23. PMID:36150233. |
this review also reveals that options for primary and secondary stroke prevention in scd are still limited to hydroxyurea and blood transfusion, and that the role of aspirin and anticoagulation in scd stroke has not been adequately studied. |
2022-09-23 |
2023-08-14 |
Not clear |
| Ava Runge, Danielle Brazel, Zahra Pakba. Stroke in sickle cell disease and the promise of recent disease modifying agents. Journal of the neurological sciences. vol 442. 2022-09-23. PMID:36150233. |
further research is urgently needed to investigate their role in stroke prevention in scd, as these novel agents target the main stroke contributors in scd - hemolysis and vaso-occlusion. |
2022-09-23 |
2023-08-14 |
Not clear |
| Vafa Alakbarzade, Chinedu Maduakor, Usman Khan, Nader Khandanpour, Elizabeth Rhodes, Anthony C Pereir. Cerebrovascular disease in sickle cell disease. Practical neurology. 2022-09-19. PMID:36123118. |
current guidelines suggest that children and adults with scd who develop acute ischaemic stroke should be transfused without delay. |
2022-09-19 |
2023-08-14 |
Not clear |
| Emily A Kringle, Enrico M Novelli, Meryl A Butters, Elizabeth R Skidmor. Validation of the NIH Toolbox-Cognition Battery against legacy neurocognitive measures in adults with cognitive impairments: An exploratory analysis. Journal of the International Neuropsychological Society : JINS. 2022-09-05. PMID:36062530. |
the purpose of this exploratory study was to describe associations between nih toolbox-cognition battery subtests and legacy measures of neurocognitive function in two samples with neurological conditions (stroke and sickle cell disease (scd)). |
2022-09-05 |
2023-08-14 |
Not clear |
| Monica L Hulbert, Melanie E Fields, Kristin P Guilliams, Priyesha Bijlani, Shalini Shenoy, Slim Fellah, Alison S Towerman, Michael M Binkley, Robert C McKinstry, Joshua S Shimony, Yasheng Chen, Cihat Eldeniz, Dustin K Ragan, Katie D Vo, Hongyu An, Jin-Moo Lee, Andria L For. Normalization of cerebral hemodynamics following hematopoietic stem cell transplant in children with sickle cell disease. Blood. 2022-08-30. PMID:36040484. |
children with sickle cell disease (scd) demonstrate cerebral hemodynamic stress and are at high risk of strokes. |
2022-08-30 |
2023-08-14 |
human |
| Sara El Hoss, Wassim El Nemer, David C Ree. Precision Medicine and Sickle Cell Disease. HemaSphere. vol 6. issue 9. 2022-08-24. PMID:35999951. |
perhaps the best current example of precision medicine in scd is the selective use of blood transfusions as primary stroke prevention in children with evidence of cerebral vasculopathy. |
2022-08-24 |
2023-08-14 |
Not clear |
| Michael S Rallo, Omar Akel, Piyush Kalakoti, Hai Su. Characteristics and outcomes of stroke hospitalizations in patients with sickle cell disease and moyamoya syndrome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 31. issue 10. 2022-08-14. PMID:35964532. |
stroke is the leading cause of death in patients with sickle cell disease (scd). |
2022-08-14 |
2023-08-14 |
Not clear |
| Michael S Rallo, Omar Akel, Piyush Kalakoti, Hai Su. Characteristics and outcomes of stroke hospitalizations in patients with sickle cell disease and moyamoya syndrome. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. vol 31. issue 10. 2022-08-14. PMID:35964532. |
here, we detail the burden of moyamoya syndrome (mms) as a cause of stroke in patients with scd. |
2022-08-14 |
2023-08-14 |
Not clear |
| Arthemon Nguweneza, Valentina Josiane Ngo Bitoungui, Khuthala Mnika, Gaston Mazandu, Victoria Nembaware, Andre P Kengne, Ambroise Wonka. Clinical characteristics and risk factors of relative systemic hypertension and hypertension among sickle cell patients in Cameroon. Frontiers in medicine. vol 9. 2022-08-05. PMID:35928290. |
increased blood pressure (bp) has been associated with higher risk of stroke and mortality in sickle cell disease (scd). |
2022-08-05 |
2023-08-14 |
Not clear |