| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jenni E Anttila, Keith W Whitaker, Emily S Wires, Brandon K Harvey, Mikko Airavaar. Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 79. issue Pt A. 2018-07-06. PMID:27389423. |
increasing evidence shows that microglia have a complex role in stroke pathophysiology, and they mediate both detrimental and beneficial effects on stroke outcome. |
2018-07-06 |
2023-08-13 |
Not clear |
| Claudia Espinosa-Garcia, Iqbal Sayeed, Seema Yousuf, Fahim Atif, Elena G Sergeeva, Gretchen N Neigh, Donald G Stei. Stress primes microglial polarization after global ischemia: Therapeutic potential of progesterone. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28648389. |
preclinical research suggests that stress primes microglia, resulting in an enhanced reactivity to a subsequent insult and potentially increasing vulnerability to stroke. |
2018-06-06 |
2023-08-13 |
rat |
| Murielle G Kluge, Laura Kracht, Mahmoud Abdolhoseini, Lin Kooi Ong, Sarah J Johnson, Michael Nilsson, Frederick R Walke. Impaired microglia process dynamics post-stroke are specific to sites of secondary neurodegeneration. Glia. vol 65. issue 12. 2018-06-05. PMID:28836304. |
in this study, we used acute slice based multiphoton imaging, to investigate microglia dynamic process movement in mice 14 days after a photothrombotic stroke. |
2018-06-05 |
2023-08-13 |
mouse |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
microglia and monocytes/macrophages polarization reveal novel therapeutic mechanism against stroke. |
2018-05-30 |
2023-08-13 |
Not clear |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
cell-based therapies, using microglia and monocytes/macrophages preconditioned by optimal stimuli and/or any therapies targeting these cells, might be an ideal therapeutic strategy for managing stroke. |
2018-05-30 |
2023-08-13 |
Not clear |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
cell-based therapies using m2-like microglia and monocytes/macrophages might be protective therapeutic strategies against stroke for three reasons. |
2018-05-30 |
2023-08-13 |
Not clear |
| Masato Kanazawa, Itaru Ninomiya, Masahiro Hatakeyama, Tetsuya Takahashi, Takayoshi Shimohat. Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke. International journal of molecular sciences. vol 18. issue 10. 2018-05-30. PMID:29027964. |
although future translational studies are required, m2-like microglia and monocytes/macrophages therapies are attractive for managing stroke based on their protective functions. |
2018-05-30 |
2023-08-13 |
Not clear |
| Jan-Kolja Strecker, Antje Schmidt, Wolf-Rüdiger Schäbitz, Jens Minneru. Neutrophil granulocytes in cerebral ischemia - Evolution from killers to key players. Neurochemistry international. vol 107. 2018-04-03. PMID:27884770. |
we further report of new findings regarding the interaction of pmns with resident microglia, immigrating macrophages and t cells after stroke. |
2018-04-03 |
2023-08-13 |
Not clear |
| Jin Hwan Lee, Zheng Z Wei, Wenyuan Cao, Soonmi Won, Xiaohuan Gu, Megan Winter, Thomas A Dix, Ling Wei, Shan Ping Y. Regulation of therapeutic hypothermia on inflammatory cytokines, microglia polarization, migration and functional recovery after ischemic stroke in mice. Neurobiology of disease. vol 96. 2018-02-09. PMID:27659107. |
seven days after focal cortical ischemia, microglia activation in the penumbra reached a peak level, which was significantly attenuated by th treatments commenced 30min after stroke. |
2018-02-09 |
2023-08-13 |
mouse |
| Jianguo Xu, Handong Wang, Seok Joon Won, Jayinee Basu, David Kapfhamer, Raymond A Swanso. Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1. Glia. vol 64. issue 11. 2018-01-04. PMID:27444121. |
brain injury resulting from stroke or trauma can be exacerbated by the release of proinflammatory cytokines, proteases, and reactive oxygen species by activated microglia. |
2018-01-04 |
2023-08-13 |
Not clear |
| Muhammad Shahdaat Bin Sayeed, Qasim Alhadidi, Zahoor A Sha. Cofilin signaling in hemin-induced microglial activation and inflammation. Journal of neuroimmunology. vol 313. 2017-11-29. PMID:29153608. |
intracerebral hemorrhage (ich) is the most severe form of stroke and is further exacerbated by the secondary injury involving inflammatory response due to the activation of microglia. |
2017-11-29 |
2023-08-13 |
Not clear |
| Maria L Cotrina, Nanghong Lou, Jessica Tome-Garcia, James Goldman, Maiken Nedergaar. Direct comparison of microglial dynamics and inflammatory profile in photothrombotic and arterial occlusion evoked stroke. Neuroscience. vol 343. 2017-11-17. PMID:28003156. |
two groups of heterozygote cx3cr1-gfp reporter mice (to follow microglia) were subject to stroke injury either with coagulator-mediated occlusion or photothrombotic mca damage. |
2017-11-17 |
2023-08-13 |
mouse |
| Maria L Cotrina, Nanghong Lou, Jessica Tome-Garcia, James Goldman, Maiken Nedergaar. Direct comparison of microglial dynamics and inflammatory profile in photothrombotic and arterial occlusion evoked stroke. Neuroscience. vol 343. 2017-11-17. PMID:28003156. |
photothrombotic stroke delayed microglial and astrocytic invasion of the ischemic core and accumulation of phagocytic microglia. |
2017-11-17 |
2023-08-13 |
mouse |
| Medha M Pathak, Truc Tran, Liang Hong, Béla Joós, Catherine E Morris, Francesco Tombol. The Hv1 proton channel responds to mechanical stimuli. The Journal of general physiology. vol 148. issue 5. 2017-10-19. PMID:27799320. |
in microglia, for example, hv1 activity is potentiated by cell swelling and causes an increase in brain damage after stroke. |
2017-10-19 |
2023-08-13 |
Not clear |
| Medha M Pathak, Truc Tran, Liang Hong, Béla Joós, Catherine E Morris, Francesco Tombol. The Hv1 proton channel responds to mechanical stimuli. The Journal of general physiology. vol 148. issue 5. 2017-10-19. PMID:27799320. |
hv1 mechanosensitivity thus provides a mechanistic link between channel activation in microglia and brain damage after stroke. |
2017-10-19 |
2023-08-13 |
Not clear |
| Ming Huang, Yan Wan, Ling Mao, Quan-Wei He, Yuan-Peng Xia, Man Li, Ya-Nan Li, Hui-Juan Jin, Bo H. Inhibiting the Migration of M1 Microglia at Hyperacute Period Could Improve Outcome of tMCAO Rats. CNS neuroscience & therapeutics. vol 23. issue 3. 2017-10-19. PMID:27991729. |
to study whether inhibiting microglia migration to the ischemic boundary zone (ibz) at the early phase could improve neurological outcomes after stroke. |
2017-10-19 |
2023-08-13 |
rat |
| Rebecca Klein, Nicolas Mahlberg, Maurice Ohren, Anne Ladwig, Bernd Neumaier, Rudolf Graf, Mathias Hoehn, Morten Albrechtsen, Stephen Rees, Gereon Rudolf Fink, Maria Adele Rueger, Michael Schroete. The Neural Cell Adhesion Molecule-Derived (NCAM)-Peptide FG Loop (FGL) Mobilizes Endogenous Neural Stem Cells and Promotes Endogenous Regenerative Capacity after Stroke. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 11. issue 4. 2017-10-18. PMID:27352075. |
here we investigated the effect of subcutaneously injected fgl on cellular compartments affected by degeneration and regeneration after stroke due to middle cerebral artery occlusion (mcao), namely endogenous neural stem cells (nsc), oligodendrocytes, and microglia. |
2017-10-18 |
2023-08-13 |
Not clear |
| Lauren J Simmons, Monique C Surles-Zeigler, Yonggang Li, Gregory D Ford, Gale D Newman, Byron D For. Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. Journal of neuroinflammation. vol 13. issue 1. 2017-10-10. PMID:27596278. |
over-activation of brain microglia can induce pro-inflammatory gene expression by activation of transcriptional regulators following stroke. |
2017-10-10 |
2023-08-13 |
rat |
| Xiaoyan Jiang, Hongjian Pu, Xiaoming Hu, Zhishuo Wei, Dandan Hong, Wenting Zhang, Yanqin Gao, Jun Chen, Yejie Sh. A Post-stroke Therapeutic Regimen with Omega-3 Polyunsaturated Fatty Acids that Promotes White Matter Integrity and Beneficial Microglial Responses after Cerebral Ischemia. Translational stroke research. vol 7. issue 6. 2017-09-26. PMID:27714669. |
notably, the improved white matter integrity and increased m2 microglia were strongly linked to the mitigation of sensorimotor deficits after stroke upon n-3 pufa treatments. |
2017-09-26 |
2023-08-13 |
mouse |
| Eunhee Kim, Sunghee Ch. Microglia and Monocyte-Derived Macrophages in Stroke. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 13. issue 4. 2017-09-22. PMID:27485238. |
microglia and monocyte-derived macrophages in stroke. |
2017-09-22 |
2023-08-13 |
Not clear |