| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thanos Karatzias, Mark Shevlin, Marylène Cloitre, Walter Busuttil, Katherine Graham, Laura Hendrikx, Philip Hyland, Natasha Biscoe, Dominic Murph. Enhanced Skills Training in Affective and Interpersonal Regulation versus Treatment as Usual for ICD-11 Complex PTSD: A Pilot Randomised Controlled Trial (The RESTORE Trial). Psychotherapy and psychosomatics. 2024-04-30. PMID:38688242. |
this pilot randomised controlled trial aimed to compare a four-module intervention developed to target all symptoms of icd-11 cptsd, namely enhanced skills in affective and interpersonal regulation (estair) with treatment as usual (tau). |
2024-04-30 |
2024-05-03 |
Not clear |
| E Fongaro, M C Picot, A Stringaris, C Belloc, A S Verissimo, N Franc, D Purper-Ouaki. Parent training for the treatment of irritability in children and adolescents: a multisite randomized controlled, 3-parallel-group, evaluator-blinded, superiority trial. BMC psychology. vol 10. issue 1. 2022-11-22. PMID:36414963. |
the aim of the study is to compare parent management training (pmt) and non-violent resistance training (nvr) programs with treatment-as-usual (tau) on the improvement of irritability in children and adolescents with a baseline parent-rated affective reactivity index of 4 or higher, in the context of adhd and other emotional and behavioural disorders. |
2022-11-22 |
2023-08-14 |
Not clear |
| Lucy L Gibson, Thomas A Pollak, Amanda Heslegrave, Abdul Hye, Lucia Batzu, Silvia Rota, Dhaval Trivedi, Timothy R Nicholson, Dominic Ffytche, Henrik Zetterberg, K Ray Chaudhuri, Dag Aarslan. Plasma Neurofilament Light and p-tau181 and Risk of Psychosis in Parkinson's Disease. Journal of Parkinson's disease. 2022-04-25. PMID:35466956. |
plasma neurofilament light (nfl) and p-tau181 are biomarkers of neuro-axonal degeneration and tau pathology respectively which have yet to be explored in association with the affective and psychotic symptoms in pd. |
2022-04-25 |
2023-08-13 |
Not clear |
| Isaline Mees, Shanshan Li, Leah C Beauchamp, Kevin J Barnham, Mathias Dutschmann, Anthony J Hannan, Thibault Renoi. Loss-of-function and gain-of-function studies refute the hypothesis that tau protein is causally involved in the pathogenesis of Huntington's disease. Human molecular genetics. 2022-01-09. PMID:34999772. |
our data suggests that neither the expression of a tau transgene nor the ablation of tau expression impacted the progression of the hd motor, cognitive and affective phenotypes. |
2022-01-09 |
2023-08-13 |
mouse |
| Isaline Mees, Shanshan Li, Leah C Beauchamp, Kevin J Barnham, Mathias Dutschmann, Anthony J Hannan, Thibault Renoi. Loss-of-function and gain-of-function studies refute the hypothesis that tau protein is causally involved in the pathogenesis of Huntington's disease. Human molecular genetics. 2022-01-09. PMID:34999772. |
however, little is known about the implication of tau in the development of hd pathophysiology, which includes motor, cognitive and affective symptoms. |
2022-01-09 |
2023-08-13 |
mouse |
| Leslie A Sandusky-Beltran, Andrii Kovalenko, Devon S Placides, Kevin Ratnasamy, Chao Ma, Jerry B Hunt, Huimin Liang, John Ivan T Calahatian, Camilla Michalski, Margaret Fahnestock, Laura J Blair, April L Darling, Jeremy D Baker, Sarah N Fontaine, Chad A Dickey, Joshua J Gamsby, Kevin R Nash, Erin Abner, Maj-Linda B Selenica, Daniel C Le. Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology. The Journal of clinical investigation. vol 131. issue 4. 2021-09-20. PMID:33586680. |
azin2 also increased acetylpolyamines, augmented tau deposition, and promoted cognitive and affective behavioral impairments. |
2021-09-20 |
2023-08-13 |
mouse |
| Leslie A Sandusky-Beltran, Andrii Kovalenko, Devon S Placides, Kevin Ratnasamy, Chao Ma, Jerry B Hunt, Huimin Liang, John Ivan T Calahatian, Camilla Michalski, Margaret Fahnestock, Laura J Blair, April L Darling, Jeremy D Baker, Sarah N Fontaine, Chad A Dickey, Joshua J Gamsby, Kevin R Nash, Erin Abner, Maj-Linda B Selenica, Daniel C Le. Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology. The Journal of clinical investigation. vol 131. issue 4. 2021-09-20. PMID:33586680. |
tauopathies display a spectrum of phenotypes from cognitive to affective behavioral impairments; however, mechanisms promoting tau pathology and how tau elicits behavioral impairment remain unclear. |
2021-09-20 |
2023-08-13 |
mouse |
| Nicole S Tommasi, Christopher Gonzalez, Danielle Briggs, Michael J Properzi, Jennifer R Gatchel, Gad A Marshal. Affective symptoms and regional cerebral tau burden in early-stage Alzheimer's disease. International journal of geriatric psychiatry. vol 36. issue 7. 2021-07-08. PMID:33682933. |
affective symptoms and regional cerebral tau burden in early-stage alzheimer's disease. |
2021-07-08 |
2023-08-13 |
Not clear |
| Yvonne Stikkelbroek, Gerko Vink, Maaike H Nauta, Marco A Bottelier, Leonieke J J Vet, Cathelijne M Lont, Anneloes L van Baar, Denise H M Bodde. Effectiveness and moderators of individual cognitive behavioral therapy versus treatment as usual in clinically depressed adolescents: a randomized controlled trial. Scientific reports. vol 10. issue 1. 2021-05-17. PMID:32908173. |
completers, cbt (n = 19) and tau (n = 26), showed a significant reduction of affective diagnoses at post treatment (76% versus 76%) and after six months (90% versus 79%). |
2021-05-17 |
2023-08-13 |
Not clear |
| Marangelie Criado-Marrero, Jonathan J Sabbagh, Margaret R Jones, Dale Chaput, Chad A Dickey, Laura J Blai. Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice. Cells. vol 9. issue 1. 2021-02-08. PMID:31947657. |
affective symptoms have often been associated with aberrant tau pathology and are commonly comorbid in patients with tauopathies, indicating a connection between tau functioning and mechanisms of depression. |
2021-02-08 |
2023-08-13 |
mouse |
| Milan Stoiljkovic, Craig Kelley, Bernardo Stutz, Tamas L Horvath, Mihály Hajó. Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 6. 2020-09-22. PMID:29920597. |
current findings suggest that accumulation of amyloid-β (aβ) and hyperphosphorylated tau in the brain disrupt synaptic function in hippocampal-cortical neuronal networks leading to impairment in cognitive and affective functions in alzheimer's disease (ad). |
2020-09-22 |
2023-08-13 |
rat |
| C Peña-Bautista, M Baquero, I Ferrer, D Hervás, M Vento, A García-Blanco, C Cháfer-Pericá. Neuropsychological assessment and cortisol levels in biofluids from early Alzheimer's disease patients. Experimental gerontology. vol 123. 2020-06-11. PMID:31117002. |
early ad patients and non-ad patients recruited at out-patient neurological unit were classified from the standard cerebrospinal fluid biomarkers levels (β-amyloid, tau, phosphorylated tau), and studied with an extensive neuropsychological assessment including global, neuropsychological, functional and affective scales. |
2020-06-11 |
2023-08-13 |
Not clear |
| Niklas Granö, Marjaana Karjalainen, Klaus Ranta, Maija Lindgren, Mikko Roine, Sebastian Therma. Community-oriented family-based intervention superior to standard treatment in improving depression, hopelessness and functioning among adolescents with any psychosis-risk symptoms. Psychiatry research. vol 237. 2016-10-12. PMID:26921045. |
the aim of the present study was to compare change in functioning, affective symptoms and level of psychosis-risk symptoms in symptomatic adolescents who were treated either in an early intervention programme based on a need-adapted family- and community-orientated integrative treatment model (fctm) or in standard adolescent psychiatric treatment (treatment as usual, tau). |
2016-10-12 |
2023-08-13 |
Not clear |
| Esther Brendel, Patricia R DeLucia, Heiko Hecht, Ryan L Stacy, Jeff T Larse. Threatening pictures induce shortened time-to-contact estimates. Attention, perception & psychophysics. vol 74. issue 5. 2012-11-06. PMID:22396120. |
a theory of ttc estimates based purely on the optical variable tau does not predict an influence of the affective value of an approaching object. |
2012-11-06 |
2023-08-12 |
human |
| Mark Doran, Daniel G du Plessis, Eric J Ghadiali, David M A Mann, Stuart Pickering-Brown, Andrew J Larne. Familial early-onset dementia with tau intron 10 + 16 mutation with clinical features similar to those of Alzheimer disease. Archives of neurology. vol 64. issue 10. 2007-11-20. PMID:17923640. |
frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17) owing to the tau intron 10 + 16 mutation usually occurs with a prototypical frontotemporal dementia phenotype with prominent disinhibition and affective disturbances. |
2007-11-20 |
2023-08-12 |
Not clear |
| Thorsten Barnhofer, Danielle Duggan, Catherine Crane, Silvia Hepburn, Melanie J V Fennell, J Mark G William. Effects of meditation on frontal alpha-asymmetry in previously suicidal individuals. Neuroreport. vol 18. issue 7. 2007-06-13. PMID:17426604. |
the tau group showed a significant deterioration toward decreased relative left-frontal activation, indexing decreases in positive affective style, while there was no significant change in the mbct group. |
2007-06-13 |
2023-08-12 |
Not clear |