| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thoria Diab, Samar Sami AlKafaas, Thanaa Ibrahim Shalaby, Mohamed Hessie. Dexamethasone simulates the anticancer effect of nano-formulated paclitaxel in breast cancer cells. Bioorganic chemistry. vol 99. 2021-03-01. PMID:32240873. |
cells viability (assessed by mtt assay), apoptosis (assessed by flow cytometry) and the expression of ptx resistance gene (trx1) and ptx metabolizing genes (cyp2c8 and cyp3a4) were investigated. |
2021-03-01 |
2023-08-13 |
Not clear |
| Lihua Cui, Caixia Li, Yuzhen Zhuo, Lei Yang, Naiqiang Cui, Yuhong Li, Shukun Zhan. Saikosaponin A inhibits the activation of pancreatic stellate cells by suppressing autophagy and the NLRP3 inflammasome via the AMPK/mTOR pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 128. 2021-03-01. PMID:32497863. |
cell viability, proliferation, migration and apoptosis were evaluated by mtt assays, the icelligence system, transwell assays and flow cytometry. |
2021-03-01 |
2023-08-13 |
rat |
| Attila Biró, Arnold Markovics, Mónika Éva Fazekas, Gábor Fidler, Gábor Szalóki, Melinda Paholcsek, János Lukács, László Stündl, Judit Remenyi. Allithiamine Alleviates Hyperglycaemia-Induced Endothelial Dysfunction. Nutrients. vol 12. issue 6. 2021-03-01. PMID:32517031. |
the non-cytotoxic concentration of allithiamine was determined based on mtt, apoptosis, and necrosis assays. |
2021-03-01 |
2023-08-13 |
human |
| Huanhuan Xu, Litian Wang, Boya Shi, Lihong Hu, Chunxia Gan, Ya Wang, Zemin Xiang, Xuanjun Wang, Jun Shen. Caffeine inhibits the anticancer activity of paclitaxel via down-regulation of α-tubulin acetylation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-03-01. PMID:32580047. |
in vitro studies, involving mtt assay, wound-healing assay, cell apoptosis assay, and western blotting analysis of a549 and hela cells, were performed. |
2021-03-01 |
2023-08-13 |
Not clear |
| Ainaz Mihanfar, Saber Ghazizadeh Darband, Shirin Sadighparvar, Mojtaba Kaviani, Mohammad Mirza-Aghazadeh-Attari, Bahman Yousefi, Maryam Majidini. In vitro and in vivo anticancer effects of syringic acid on colorectal cancer: Possible mechanistic view. Chemico-biological interactions. vol 337. 2021-03-01. PMID:33548266. |
in vitro effects of syringic acid treatment on human colorectal cancer sw-480 cell lines were assessed by performing cell proliferation assay (mtt and trypan blue staining), apoptosis assays (tunel assay, annexin-v/pi flowcytometry and lactate dehydrogenase release assay), measuring reactive oxygen species (ros), antioxidant enzymes and dna damage, and evaluating protein levels of proliferative genes, and autophagy markers. |
2021-03-01 |
2023-08-13 |
human |
| Baiqi Wang, Lili Xu, Ju Zhang, Xinru Cheng, Qianya Xu, Jian Wang, Fengxia Ma. LncRNA NORAD accelerates the progression and doxorubicin resistance of neuroblastoma through up-regulating HDAC8 via sponging miR-144-3p. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 129. 2021-02-26. PMID:32563146. |
the proliferation, chemoresistance, apoptosis, metastasis and autophagy of nb cells were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flow cytometry, transwell migration and invasion assays and western blot assay, respectively. |
2021-02-26 |
2023-08-13 |
Not clear |
| Anquan Shang, Weiwei Wang, Chenzheng Gu, Wei Chen, Wenying Lu, Zujun Sun, Dong L. Long non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression. Aging. vol 12. issue 9. 2021-02-25. PMID:32380476. |
cell viability, colony formation ability, aggression and apoptosis were determined by mtt assay, colony formation assay, transwell and wound healing assays and flow cytometry analysis. |
2021-02-25 |
2023-08-13 |
Not clear |
| Mehrnaz Mehrabani, Mohammad Hadi Nematollahi, Mojde Esmaeili Tarzi, Kobra Bahrampour Juybari, Moslem Abolhassani, Ali Mohammad Sharifi, Hamze Paseban, Mohsen Saravani, Solmaz Mirzamohammad. Protective effect of hydralazine on a cellular model of Parkinson's disease: a possible role of hypoxia-inducible factor (HIF)-1α. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 98. issue 3. 2021-02-24. PMID:31940231. |
the cytotoxicity of hydralazine and 6-ohda on the sh-sy5y cells were evaluated by mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and apoptosis detection assays. |
2021-02-24 |
2023-08-13 |
Not clear |
| Qigang Xu, Wei Lin, Chonglin Tao, Xiaming Huang, Junjian L. Chondroitin polymerizing factor (CHPF) contributes to malignant proliferation and migration of hepatocellular carcinoma cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 98. issue 3. 2021-02-24. PMID:32383983. |
mtt assays, colony formation assays, and flow cytometry were used to evaluate the cell proliferation, colony formation, and cell apoptosis, respectively. |
2021-02-24 |
2023-08-13 |
human |
| Bin Lin, Jing Xu, Feng Wang, Jiaxiang Wang, Hui Zhao, Deguang Fen. LncRNA XIST promotes myocardial infarction by regulating Aging. vol 12. issue 8. 2021-02-23. PMID:32315985. |
mtt assay and flow cytometry were used to determine proliferation and apoptosis respectively. |
2021-02-23 |
2023-08-13 |
mouse |
| Nerella Sridhar Goud, Venkata Krishna Kanth Makani, Jakkula Pranay, Ravi Alvala, Insaf A Qureshi, Pardeep Kumar, Rose Dawn Bharath, Chandana Nagaraj, Suresh Yerramsetty, Manika Pal-Bhadra, Mallika Alval. Synthesis, Bioorganic chemistry. vol 97. 2021-02-22. PMID:32106038. |
synthesis, in present study, a new series of 4, 7-disubstituted coumarin derivatives (7a-y) have been synthesized as galectin-1 targeting apoptosis inducing agents and evaluated for their in vitro cytotoxic potentials against a panel of selected human cancer cell lines namely, brest (mcf7), ovarian (skov3), prostate (pc-3 & du145) and normal embryonic kidney (hek293t) cells, using mtt assay. |
2021-02-22 |
2023-08-13 |
human |
| Long Cheng, Zihe Xing, Peng Zhang, Wuqin X. Long non-coding RNA LINC00662 promotes proliferation and migration of breast cancer cells via regulating the miR-497-5p/EglN2 axis. Acta biochimica Polonica. vol 67. issue 2. 2021-02-19. PMID:32558530. |
moreover, the mtt assay, wound-healing assay, colony-forming assay and transwell assay were employed in mda-mb-157 cells to detect the effect of linc00662 on cell apoptosis, invasion, migration and proliferation, respectively. |
2021-02-19 |
2023-08-13 |
human |
| Alicia Arranz-Romera, Maria Hernandez, Patricia Checa-Casalengua, Alfredo Garcia-Layana, Irene T Molina-Martinez, Sergio Recalde, Michael J Young, Budd A Tucker, Rocío Herrero-Vanrell, Patricia Fernandez-Robredo, Irene Bravo-Osun. A Safe GDNF and GDNF/BDNF Controlled Delivery System Improves Migration in Human Retinal Pigment Epithelial Cells and Survival in Retinal Ganglion Cells: Potential Usefulness in Degenerative Retinal Pathologies. Pharmaceuticals (Basel, Switzerland). vol 14. issue 1. 2021-02-18. PMID:33440745. |
in vitro release, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) cell viability, terminal deoxynucleotidyl transferase (tdt) deoxyuridine dutp nick-end labelling (tunel) apoptosis, functional wound healing migration (arpe-19; migration), and (rf/6a; angiogenesis) assays were conducted. |
2021-02-18 |
2023-08-13 |
mouse |
| Jinchuan Chen, Rujie Qi. MicroRNA‑138‑5p regulates the development of spinal cord injury by targeting SIRT1. Molecular medicine reports. vol 22. issue 1. 2021-02-16. PMID:32319664. |
then, mtt assay, flow cytometry and elisa experiments were performed to analyze cell viability, apoptosis, and the levels of tumor necrosis factor‑α, interleukin (il)‑1β and il‑6. |
2021-02-16 |
2023-08-13 |
rat |
| Yongli Hu, Bing Wang, Lie Wang, Zhenran Wang, Zhiyuan Jian, Lin Den. Mammalian STE20‑like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2‑mediated mitophagy. Molecular medicine reports. vol 22. issue 1. 2021-02-16. PMID:32377725. |
moreover, mst1 overexpression in panc‑1 cells led to increased apoptosis as determined by mtt and tunel assays and inhibited cellular migration. |
2021-02-16 |
2023-08-13 |
Not clear |
| Qiang Xue, Dong Yang, Jilei Zhang, Pin Gan, Chunrong Lin, Yibing Lu, Weihua Zhang, Li Zhang, Xuefeng Guan. USP7, negatively regulated by miR-409-5p, aggravates hypoxia-induced cardiomyocyte injury. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 129. issue 3. 2021-02-16. PMID:33241864. |
after usp7 and mir-409-5p were selectively regulated in h9c2 cells, the inflammatory response, apoptosis, and cell viability were detected by elisa, flow cytometry, and mtt assay, respectively. |
2021-02-16 |
2023-08-13 |
rat |
| Yongkun Wang, Tingting Liang, Yao Wang, Yan Huang, Ye L. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation. American journal of cancer research. vol 7. issue 4. 2021-02-12. PMID:28469961. |
cell proliferation, viability, and apoptosis were measured using ki-67 proliferation assay, mtt assay, and annexin v/pi staining assay, respectively. |
2021-02-12 |
2023-08-13 |
human |
| Yao Sh. MEG3 regulates apoptosis of adipose‑derived stem cells. Molecular medicine reports. vol 21. issue 6. 2021-02-12. PMID:32323784. |
meg3 was overexpressed in adscs and these cells were evaluated for viability, tp53 expression, apoptosis, morphology, and bax and bcl‑2 expression by performing mtt assays, reverse transcription‑quantitative pcr, flow cytometry analysis and western blotting. |
2021-02-12 |
2023-08-13 |
Not clear |
| Sujin Kim, Suji Kim, Ae-Rang Hwang, Hyoung Chul Choi, Ji-Yun Lee, Chang-Hoon Wo. Apelin-13 Inhibits Methylglyoxal-Induced Unfolded Protein Responses and Endothelial Dysfunction via Regulating AMPK Pathway. International journal of molecular sciences. vol 21. issue 11. 2021-02-12. PMID:32517197. |
mgo-induced er stress and apoptosis were determined by immunoblotting and mtt assay in huvecs. |
2021-02-12 |
2023-08-13 |
mouse |
| Marjan Aghajani, Ahad Mokhtarzadeh, Leili Aghebati-Maleki, Behzad Mansoori, Ali Mohammadi, Sahar Safaei, Zahra Asadzadeh, Khalil Hajiasgharzadeh, Vahid Khaze Shahgoli, Behzad Baradara. CD133 suppression increases the sensitivity of prostate cancer cells to paclitaxel. Molecular biology reports. vol 47. issue 5. 2021-02-11. PMID:32246247. |
to measure the cell viability, migratory capacity, cscs properties, invasive potential, apoptosis and cell cycle progression of the cells, the mtt, wound healing, spheroid assay, colony formation assay, dapi staining and flow cytometry assays were applied in the lncap cell line, respectively. |
2021-02-11 |
2023-08-13 |
Not clear |