| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marcin Piechota, Urszula Skupio, Małgorzata Borczyk, Barbara Ziółkowska, Sławomir Gołda, Łukasz Szumiec, Klaudia Szklarczyk-Smolana, Wiktor Bilecki, Jan Manuel Rodriguez Parkitna, Michał Korostyńsk. Glucocorticoid-Regulated Kinase CAMKIγ in the Central Amygdala Controls Anxiety-like Behavior in Mice. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293185. |
thus, we confirm that camk1g is a neuron-specific gr-regulated transcript, and show that it is specifically involved in behaviors related to anxiety, as well as responses conditioned by aversive stimuli. |
2022-10-27 |
2023-08-14 |
mouse |
| Stephanie M Staszko, John D Boughter, Max L Fletche. The impact of familiarity on cortical taste coding. Current biology : CB. 2022-10-19. PMID:36261035. |
the role of the gustatory region of the insular cortex in mediating associative taste learning, such as conditioned taste aversion, has been well studied. |
2022-10-19 |
2023-08-14 |
mouse |
| G N Zyuz'kov, V V Zhdanov, L A Miroshnichenko, T Yu Polyakova, L A Stavrova, E V Simanina, M Yu Minakova, V I Agafonov, A A Churi. Psychopharmacological Effects of Stimulation of the Functions of Neural Stem Cells by STAT3 Inhibitor under Conditions of Modeled Ethanol-Induced Encephalopathy. Bulletin of experimental biology and medicine. 2022-10-09. PMID:36210414. |
at the same time, the reproducibility of the conditioned passive avoidance response developed at the beginning of the course stat3 inhibitor administration decreased. |
2022-10-09 |
2023-08-14 |
mouse |
| Jia-Ying Li, Yang-Jung Yu, Chun-Lin Su, Yu-Qi Shen, Chih-Hua Chang, Po-Wu Gea. Modulation of methamphetamine memory reconsolidation by neural projection from basolateral amygdala to nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-09-15. PMID:36109595. |
the basolateral amygdala (bla) involves the association of conditioned cues with reward and aversive valences and projects the information to the nucleus accumbens (nac) that mediates reward-seeking. |
2022-09-15 |
2023-08-14 |
mouse |
| Lauren Kuhns, Emese Kroon, Heidi Lesscher, Gabry Mies, Janna Cousij. Age-related differences in the effect of chronic alcohol on cognition and the brain: a systematic review. Translational psychiatry. vol 12. issue 1. 2022-08-25. PMID:36008381. |
human evidence is largely missing, but animal research provides limited but consistent evidence of heightened adolescent sensitivity to chronic alcohol's effects on several outcomes, including conditioned aversion, dopaminergic transmission in reward-related regions, neurodegeneration, and neurogenesis. |
2022-08-25 |
2023-08-14 |
human |
| Samantha L Regan, Chiho Sugimoto, Hannah E Dawson, Michael T Williams, Charles V Vorhee. Latrophilin-3 heterozygous versus homozygous mutations in Sprague Dawley rats: Effects on egocentric and allocentric memory and locomotor activity. Genes, brain, and behavior. 2022-08-19. PMID:35985692. |
we tested the rats in home-cage activity starting at postnatal day (p)35 and p50, followed by tests of egocentric learning (cincinnati water maze [cwm]), spatial learning (morris water maze [mwm]), working memory (radial water maze [rwm]), incidental learning (novel object recognition [nor]), acoustic startle response (asr) habituation, tactile startle response (tsr) habituation, prepulse modification of acoustic startle, shuttle-box passive avoidance, conditioned freezing, and a mirror image version of the cwm. |
2022-08-19 |
2023-08-14 |
human |
| Samantha L Regan, Chiho Sugimoto, Hannah E Dawson, Michael T Williams, Charles V Vorhee. Latrophilin-3 heterozygous versus homozygous mutations in Sprague Dawley rats: Effects on egocentric and allocentric memory and locomotor activity. Genes, brain, and behavior. 2022-08-19. PMID:35985692. |
ko and het rats had egocentric (cwm) and spatial deficits (mwm), increased startle response, and ko rats showed less conditioned freezing on contextual and cued memory; there were no effects on working memory (rwm) or passive avoidance. |
2022-08-19 |
2023-08-14 |
human |
| Verenice Ascencio Gutierrez, Audrey A Carrillo, Gretha J Boersma, Kellie L K Tamashiro, Timothy H Moran, Sergio D Iñiguez, Yada Treesukoso. Effect of early-life stress or fluoxetine exposure on later-life conditioned taste aversion learning in Sprague-Dawley rats. Neuroscience letters. 2022-08-05. PMID:35931277. |
to expand on this line of work, we evaluated how juvenile exposure to chronic variable stress (cvs) or the selective serotonin reuptake inhibitor fluoxetine (flx) influences conditioned taste aversion (cta) learning in adulthood. |
2022-08-05 |
2023-08-14 |
rat |
| Ling Bai, Nilla Sivakumar, Shenliang Yu, Sheyda Mesgarzadeh, Tom Ding, Truong Ly, Timothy V Corpuz, James C R Grove, Brooke C Jarvie, Zachary A Knigh. Enteroendocrine cell types that drive food reward and aversion. eLife. vol 11. 2022-08-01. PMID:35913117. |
conditioned flavor preference is driven by release of cholecystokinin whereas conditioned taste aversion is mediated by serotonin and substance p. these positive and negative valence signals are transmitted by vagal and spinal afferents, respectively. |
2022-08-01 |
2023-08-14 |
mouse |
| J Titulaer, O Radhe, K Danielsson, S Dutheil, M M Marcus, K Jardemark, T H Svensson, G L Snyder, M Ericson, R E Davis, Å Konradsson-Geuke. Lumateperone-mediated effects on prefrontal glutamatergic receptor-mediated neurotransmission: A dopamine D European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 62. 2022-07-25. PMID:35878581. |
we used the conditioned avoidance response (car) test to determine the antipsychotic-like effect of lumateperone, electrophysiology in vitro to study lumateperone's effects on nmda- and ampa-induced currents in the mpfc, and the neurochemical techniques microdialysis and amperometry to measure dopamine- and glutamate release in the rat mpfc. |
2022-07-25 |
2023-08-14 |
rat |
| Zachariah Bertels, Isaac J Dripps, Pal Shah, Laura S Moye, Alycia F Tipton, Kendra Siegersma, Amynah A Pradha. Delta opioid receptors in Nav1.8 expressing peripheral neurons partially regulate the effect of delta agonist in models of migraine and opioid-induced hyperalgesia. Neurobiology of pain (Cambridge, Mass.). vol 12. 2022-07-21. PMID:35859654. |
regardless of genotype, snc80 continued to inhibit conditioned place aversion associated with nitroglycerin and decreased cortical spreading depression events associated with migraine aura. |
2022-07-21 |
2023-08-14 |
mouse |
| Xiaotian Yu, Fasika Jembere, Kaori Takehara-Nishiuch. Prefrontal projections to the nucleus reuniens signal behavioral relevance of stimuli during associative learning. Scientific reports. vol 12. issue 1. 2022-07-14. PMID:35835794. |
one example is trace eyeblink conditioning, in which the mpfc exhibits differential activity to neutral conditioned stimuli (cs) depending on their contingency with an aversive unconditioned stimulus (us). |
2022-07-14 |
2023-08-14 |
rat |
| Shriya Palchaudhuri, Denys Osypenko, Ralf Schneggenburge. Fear Learning: An Evolving Picture for Plasticity at Synaptic Afferents to the Amygdala. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 2022-07-13. PMID:35822657. |
in fear learning, an innocuous sensory event such as a tone (called the conditioned stimulus, cs) acquires an emotional value when paired with an aversive outcome (unconditioned stimulus, us). |
2022-07-13 |
2023-08-14 |
Not clear |
| Laurel R Seemiller, Sheree F Logue, Thomas J Goul. Inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes from adolescence to adulthood. Pharmacology, biochemistry, and behavior. 2022-07-12. PMID:35820468. |
this review summarizes inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes including voluntary consumption/self-administration, initial sensitivity to the drug as measured by sedative, hypothermic, and ataxic effects, locomotor effects, conditioned place preference or place aversion, drug metabolism and severity of withdrawal symptoms. |
2022-07-12 |
2023-08-14 |
mouse |
| Eric D Zaizar, Santiago Papini, Patrick O'Connor, Michael J Telc. Impact of cannabidiol-rich hemp extract oil on reconsolidation disruption of naturalistic interoceptive aversive memory in humans: Protocol for a randomized clinical trial. Contemporary clinical trials. 2022-07-10. PMID:35811050. |
preclinical experiments with rodents demonstrate that cannabidiol (cbd), the non-psychotomimetic constituent of the cannabis sativa plant, disrupts reconsolidation of aversive memories conditioned in the laboratory when administered within the memory reconsolidation window (< 6 h. |
2022-07-10 |
2023-08-14 |
Not clear |
| Ian T Kim, Claudia Farb, Mian Hou, Sunanda Prasad, Elyse Talley, Savannah Cook, Vincent D Campes. General and Specific Aversive Modulation of Active Avoidance Require Central Amygdala. Frontiers in behavioral neuroscience. vol 16. 2022-07-07. PMID:35795380. |
three studies provide evidence that the central nucleus of the amygdala, a structure with a well-established role in conditioned freezing, is also required for conditioned facilitation of instrumental avoidance in rats. |
2022-07-07 |
2023-08-14 |
human |
| Bridget L Kajs, Adrienne C Loewke, Jeffrey M Dorsch, Leah T Vinson, Lisa A Gunaydi. Divergent encoding of active avoidance behavior in corticostriatal and corticolimbic projections. Scientific reports. vol 12. issue 1. 2022-06-24. PMID:35750718. |
we examined neural activity during conditioned stimulus (cs) presentations and during clinically relevant behaviors such as active avoidance or cued freezing. |
2022-06-24 |
2023-08-14 |
mouse |
| Zhenfu Wen, Candace M Raio, Edward F Pace-Schott, Sara W Lazar, Joseph E LeDoux, Elizabeth A Phelps, Mohammed R Mila. Temporally and anatomically specific contributions of the human amygdala to threat and safety learning. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 26. 2022-06-21. PMID:35727981. |
in 601 humans, we show that two amygdala subregions tracked the conditioned stimulus with aversive shock during early conditioning while only one demonstrated delayed responding to a stimulus not paired with shock. |
2022-06-21 |
2023-08-14 |
human |
| Salma E Reyes-García, Beatriz Gutiérrez-Vera, Martha L Escoba. Calcineurin requirement for in vivo insular cortex LTD and CTA-extinction. Neurobiology of learning and memory. 2022-06-09. PMID:35679998. |
indeed, studies of our research group have demonstrated that induction of ltd in the basolateral nucleus of the amygdala (bla) to the insular cortex (ic) pathway facilitates the extinction of conditioned taste aversion (cta), while the induction of ltp in this pathway slows it down. |
2022-06-09 |
2023-08-14 |
rat |
| Jelena M Wehrli, Yanfang Xia, Samuel Gerster, Dominik R Bac. Measuring human trace fear conditioning. Psychophysiology. 2022-06-08. PMID:35675529. |
trace fear conditioning is an important research paradigm to model aversive learning in biological or clinical scenarios, where predictors (conditioned stimuli, cs) and aversive outcomes (unconditioned stimuli, us) are separated in time. |
2022-06-08 |
2023-08-14 |
human |