| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bridget L Kajs, Adrienne C Loewke, Jeffrey M Dorsch, Leah T Vinson, Lisa A Gunaydi. Divergent encoding of active avoidance behavior in corticostriatal and corticolimbic projections. Scientific reports. vol 12. issue 1. 2022-06-24. PMID:35750718. |
active avoidance requires the dorsomedial prefrontal cortex (dmpfc), which is thought to regulate avoidance via downstream projections to the striatum and amygdala. |
2022-06-24 |
2023-08-14 |
mouse |
| Theodoros Tsetsenis, Julia K Badyna, Rebecca Li, John A Dan. Activation of a Locus Coeruleus to Dorsal Hippocampus Noradrenergic Circuit Facilitates Associative Learning. Frontiers in cellular neuroscience. vol 16. 2022-05-02. PMID:35496910. |
neuromodulation in the hippocampus and prefrontal cortex plays an important role in the formation of associations between environmental cues and an aversive experience. |
2022-05-02 |
2023-08-13 |
Not clear |
| Valerio Alfieri, Andrea Mattera, Gianluca Baldassarr. Neural Circuits Underlying Social Fear in Rodents: An Integrative Computational Model. Frontiers in systems neuroscience. vol 16. 2022-03-30. PMID:35350477. |
social avoidance in rodents arises from a complex interplay between the prefrontal cortex and subcortical structures, such as the ventromedial hypothalamus and the dorsal periaqueductal gray matter. |
2022-03-30 |
2023-08-13 |
Not clear |
| Heather S Mayer, Zachary J Rosinger, Vivian B Kruithof, Shambhavi Mishra, Anthony L BlackOwl, Danielle S Stolzenber. Effects of maternal experience on pup-induced activation of maternal neural circuits in virgin mice. Hormones and behavior. vol 141. 2022-02-15. PMID:35168026. |
whereas initial pup exposure induced c-fos activation exclusively in the medial preoptic area (mpoa), following repeated experience, c-fos expression was significantly higher than baseline in multiple regions of maternal and central aversion circuits (e.g., ventral bed nucleus of the stria terminalis, nucleus accumbens, basolateral amygdala, prefrontal cortex, medial amygdala, and ventromedial nucleus of the hypothalamus). |
2022-02-15 |
2023-08-13 |
mouse |
| Nancy R Mack, Suixin Deng, Sha-Sha Yang, Yousheng Shu, Wen-Jun Ga. Prefrontal Cortical Control of Anxiety: Recent Advances. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. 2022-01-28. PMID:35086369. |
approach-avoidance conflict tasks have been extensively used in animal research to better understand how changes in neural activity within the prefrontal cortex contribute to avoidance behaviors, which are believed to play a major role in the maintenance of anxiety disorders. |
2022-01-28 |
2023-08-13 |
Not clear |
| Candela Sánchez-Bellot, Rawan AlSubaie, Karyna Mishchanchuk, Ryan W S Wee, Andrew F MacAskil. Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour. Nature communications. vol 13. issue 1. 2022-01-18. PMID:35039510. |
two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour. |
2022-01-18 |
2023-08-13 |
Not clear |
| Candela Sánchez-Bellot, Rawan AlSubaie, Karyna Mishchanchuk, Ryan W S Wee, Andrew F MacAskil. Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour. Nature communications. vol 13. issue 1. 2022-01-18. PMID:35039510. |
the superficial population is preferentially connected to widespread pfc inhibitory interneurons, and its activation promotes exploration; while the deep circuit is connected to pfc pyramidal neurons and fast spiking interneurons, and its activation promotes avoidance. |
2022-01-18 |
2023-08-13 |
Not clear |
| Candela Sánchez-Bellot, Rawan AlSubaie, Karyna Mishchanchuk, Ryan W S Wee, Andrew F MacAskil. Two opposing hippocampus to prefrontal cortex pathways for the control of approach and avoidance behaviour. Nature communications. vol 13. issue 1. 2022-01-18. PMID:35039510. |
together this provides a mechanism for regulation of behaviour during approach avoidance conflict: through two specialized, parallel circuits that allow bidirectional hippocampal control of pfc. |
2022-01-18 |
2023-08-13 |
Not clear |
| Itamar S Grunfeld, Ekaterina Likhti. The paradoxical effects of chronic stress on avoidance: a role for amygdala-dorsomedial prefrontal cortex dialogue. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-01-13. PMID:35022537. |
the paradoxical effects of chronic stress on avoidance: a role for amygdala-dorsomedial prefrontal cortex dialogue. |
2022-01-13 |
2023-08-13 |
Not clear |
| Margaux M Kenwood, Ned H Kalin, Helen Barba. The prefrontal cortex, pathological anxiety, and anxiety disorders. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 47. issue 1. 2021-12-12. PMID:34400783. |
disruption of specific nodes within the pfc that interface with inhibitory systems can affect the negative bias, failure to regulate autonomic arousal, and avoidance that characterize anxiety disorders. |
2021-12-12 |
2023-08-13 |
Not clear |
| Francesca Guida, Monica Iannotta, Gabriella Misso, Flavia Ricciardi, Serena Boccella, Virginia Tirino, Michela Falco, Vincenzo Desiderio, Rosmara Infantino, Gorizio Pieretti, Vito de Novellis, Gianpaolo Papaccio, Livio Luongo, Michele Caraglia, Sabatino Maion. Long-term neuropathic pain behaviors correlate with synaptic plasticity and limbic circuits alteration: a comparative observational study in mice. Pain. 2021-12-05. PMID:34862336. |
in the present study, we used the spared nerve injury (sni) model to characterize the development of sensory and aversive components of neuropathic pain, and to determine their electrophysiological impact across pfc and limbic regions. |
2021-12-05 |
2023-08-13 |
mouse |
| Adrienne C Loewke, Adelaide R Minerva, Alexandra B Nelson, Anatol C Kreitzer, Lisa A Gunaydi. Frontostriatal Projections Regulate Innate Avoidance Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 25. 2021-11-19. PMID:34001628. |
the dorsomedial prefrontal cortex (dmpfc) has been linked to avoidance and decision-making under conflict, key neural computations altered in anxiety disorders. |
2021-11-19 |
2023-08-13 |
mouse |
| Anna Li, Yaling Liu, Qiaosheng Zhang, Isabel Friesner, Hyun Jung Jee, Zhe Sage Chen, Jing Wan. Disrupted population coding in the prefrontal cortex underlies pain aversion. Cell reports. vol 37. issue 6. 2021-11-10. PMID:34758316. |
disrupted population coding in the prefrontal cortex underlies pain aversion. |
2021-11-10 |
2023-08-13 |
rat |
| Marise B Parent, Hildebrando Candido Ferreira-Neto, Ana Rafaela Kruemmel, Ferdinand Althammer, Atit A Patel, Sreinick Keo, Kathryn E Whitley, Daniel N Cox, Javier E Ster. Heart failure impairs mood and memory in male rats and down-regulates the expression of numerous genes important for synaptic plasticity in related brain regions. Behavioural brain research. vol 414. 2021-11-04. PMID:34274373. |
we induced hf in male rats and tested mood and anxiety (sucrose preference and elevated plus maze) and memory (spontaneous alternation and inhibitory avoidance) and measured the simultaneous expression of 84 synaptic plasticity-associated genes in dorsal (dh) and ventral hippocampus (vh), basolateral (bla) and central amygdala (cea) and prefrontal cortex (pfc). |
2021-11-04 |
2023-08-13 |
rat |
| Patrick J F Clarke, Bram Van Bockstaele, Welber Marinovic, Joel A Howell, Mark E Boyes, Lies Notebaer. The effects of left DLPFC tDCS on emotion regulation, biased attention, and emotional reactivity to negative content. Cognitive, affective & behavioral neuroscience. vol 20. issue 6. 2021-10-25. PMID:33123862. |
the current study sought to determine whether left dorsolateral prefrontal cortex tdcs, in combination with intentional down-regulation of emotional responses would reduce negative appraisals of aversive content during emotional regulation (assessed during online tdcs), reduce patterns of biased attention and attention bias variability (assessed offline), and attenuate spontaneous (uninstructed) emotional reactivity to negative content (assessed offline) above tdcs or intentional down-regulation of emotions in isolation. |
2021-10-25 |
2023-08-13 |
human |
| Stephen Lisk, Kathrin Cohen Kadosh, Catharina Zich, Simone Pw Haller, Jennifer Yf La. Training negative connectivity patterns between the dorsolateral prefrontal cortex and amygdala through fMRI-based neurofeedback to target adolescent socially-avoidant behaviour. Behaviour research and therapy. vol 135. 2021-10-18. PMID:33137695. |
we used fmri-based neurofeedback (nf) to increase 'adaptive' patterns of negative connectivity between the dorsolateral prefrontal cortex (dlpfc) and the amygdala to change reappraisal ability, and alter social avoidance and approach behaviours in adolescents. |
2021-10-18 |
2023-08-13 |
human |
| Alexander Weigard, Stephen J Wilson, Zvi Shapiro, Hilary Galloway-Long, Cynthia Huang-Polloc. Neural correlates of working memory's suppression of aversive olfactory distraction effects. Brain imaging and behavior. vol 15. issue 5. 2021-10-12. PMID:33405095. |
overall, results suggest that, under high working memory demands, areas of the prefrontal cortex and cerebellum shield cognition from aversive distraction, potentially through interactions with brain structures involved in off-task processes. |
2021-10-12 |
2023-08-13 |
human |
| David S Jacobs, Bita Moghadda. Medial prefrontal cortex encoding of stress and anxiety. International review of neurobiology. vol 158. 2021-10-11. PMID:33785149. |
when an organism is experiencing an aversive event, such as a sustained state of anxiety or an overt experience of fear or stress, the mechanisms that govern pfc regulation of action selection may be critical for survival. |
2021-10-11 |
2023-08-13 |
human |
| David S Jacobs, Bita Moghadda. Medial prefrontal cortex encoding of stress and anxiety. International review of neurobiology. vol 158. 2021-10-11. PMID:33785149. |
a large body of literature has shown that acute aversive states influence the activity of pfc neurons and the release of neurotransmitters in this region. |
2021-10-11 |
2023-08-13 |
human |
| Stefanie L Kunas, Felix Bermpohl, Irene S Plank, Andreas Ströhle, Heiner Stuk. Aversive drug cues reduce cigarette craving and increase prefrontal cortex activation during processing of cigarette cues in quitting motivated smokers. Addiction biology. 2021-08-24. PMID:34427358. |
aversive drug cues reduce cigarette craving and increase prefrontal cortex activation during processing of cigarette cues in quitting motivated smokers. |
2021-08-24 |
2023-08-13 |
human |