| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P S Pagel, L T Proctor, A Devcic, D A Hettrick, J R Kersten, J P Tessmer, N E Farber, W T Schmeling, D C Warltie. A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs. Journal of cardiothoracic and vascular anesthesia. vol 12. issue 4. 1998-10-27. PMID:9713732. |
to test the hypothesis that l-659,066, a peripherally acting alpha 2-adrenoceptor agonist, will abolish the early pressor response but preserve the late depressor action of intravenous dexmedetomidine in conscious, unsedated dogs. |
1998-10-27 |
2023-08-12 |
Not clear |
| P S Pagel, D A Hettrick, J R Kersten, D C Warltie. Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy. Anesthesiology. vol 89. issue 3. 1998-10-01. PMID:9743413. |
dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy. |
1998-10-01 |
2023-08-12 |
Not clear |
| P S Pagel, D A Hettrick, J R Kersten, D C Warltie. Dexmedetomidine produces similar alterations in the determinants of left ventricular afterload in conscious dogs before and after the development of pacing-induced cardiomyopathy. Anesthesiology. vol 89. issue 3. 1998-10-01. PMID:9743413. |
the authors tested the hypothesis that intravenous dexmedetomidine produces alterations in left ventricular (lv) afterload that are deleterious to cardiac performance in conscious dogs with pacing-induced cardiomyopathy. |
1998-10-01 |
2023-08-12 |
Not clear |
| N E Farber, K A Poterack, W T Schmelin. Dexmedetomidine and halothane produce similar alterations in electroencephalographic and electromyographic activity in cats. Brain research. vol 774. issue 1-2. 1998-03-11. PMID:9452201. |
hemodynamics, eeg and emg were recorded in the conscious state and after randomly administered halothane or intravenous dexmedetomidine (on separate days). |
1998-03-11 |
2023-08-12 |
Not clear |
| N E Farber, K A Poterack, W T Schmelin. Dexmedetomidine and halothane produce similar alterations in electroencephalographic and electromyographic activity in cats. Brain research. vol 774. issue 1-2. 1998-03-11. PMID:9452201. |
halothane and dexmedetomidine produced differing effects on level of consciousness as assessed by response to tail clamping. |
1998-03-11 |
2023-08-12 |
Not clear |
| J R Kersten, P S Pagel, D A Hettrick, D C Warltie. Dexmedetomidine partially attenuates the sympathetically mediated systemic and coronary hemodynamic effects of cocaine. Anesthesia and analgesia. vol 80. issue 1. 1995-01-24. PMID:7802267. |
this investigation examined the systemic and coronary hemodynamic effects of cocaine in conscious dogs with and without premedication with dexmedetomidine (dm). |
1995-01-24 |
2023-08-12 |
Not clear |
| G Horváth, M Kovács, M Szikszay, G Benede. Mydriatic and antinociceptive effects of intrathecal dexmedetomidine in conscious rats. European journal of pharmacology. vol 253. issue 1-2. 1994-07-26. PMID:7912198. |
mydriatic and antinociceptive effects of intrathecal dexmedetomidine in conscious rats. |
1994-07-26 |
2023-08-12 |
rat |
| L T Proctor, W T Schmeling, D Roerig, J P Kampine, D C Warltie. Oral dexmedetomidine attenuates hemodynamic responses during emergence from general anesthesia in chronically instrumented dogs. Anesthesiology. vol 74. issue 1. 1991-02-08. PMID:1670911. |
this investigation evaluated the hemodynamic effects of orally administered dexmedetomidine in chronically instrumented dogs in the conscious state, during enflurane anesthesia, and after emergence. |
1991-02-08 |
2023-08-11 |
Not clear |
| L T Proctor, W T Schmeling, D Roerig, J P Kampine, D C Warltie. Oral dexmedetomidine attenuates hemodynamic responses during emergence from general anesthesia in chronically instrumented dogs. Anesthesiology. vol 74. issue 1. 1991-02-08. PMID:1670911. |
in groups 1 and 2, dexmedetomidine (10 or 20 micrograms/kg, respectively) was administered orally, and hemodynamics, arterial blood gas tensions, and plasma norepinephrine concentrations were monitored for 6 h. animals in groups 3 and 4 were given dexmedetomidine (20 micrograms/kg) or placebo orally, and hemodynamics, arterial blood gas tensions, and plasma norepinephrine concentrations were measured 1 h later with animals in the conscious state, after 30 min of enflurane anesthesia (1.0 mac), and 2 and 7 min after extubation. |
1991-02-08 |
2023-08-11 |
Not clear |