| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fabrice Jollant, Natalia S Lawrence, Emilie Olie, Owen O'Daly, Alain Malafosse, Philippe Courtet, Mary L Phillip. Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior. NeuroImage. vol 51. issue 3. 2010-08-05. PMID:20302946. |
decision-making impairment has been linked to orbitofrontal cortex lesions and to different disorders including substance abuse, aggression and suicidal behavior. |
2010-08-05 |
2023-08-12 |
Not clear |
| Fabrice Jollant, Natalia S Lawrence, Emilie Olie, Owen O'Daly, Alain Malafosse, Philippe Courtet, Mary L Phillip. Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior. NeuroImage. vol 51. issue 3. 2010-08-05. PMID:20302946. |
altered processing of risk under conditions of uncertainty, associated with left lateral orbitofrontal cortex dysfunction, could explain the decision-making deficits observed in suicide attempters. |
2010-08-05 |
2023-08-12 |
Not clear |
| Fabrice Jollant, Natalia S Lawrence, Emilie Olie, Owen O'Daly, Alain Malafosse, Philippe Courtet, Mary L Phillip. Decreased activation of lateral orbitofrontal cortex during risky choices under uncertainty is associated with disadvantageous decision-making and suicidal behavior. NeuroImage. vol 51. issue 3. 2010-08-05. PMID:20302946. |
these results also add to our growing understanding of the role of the orbitofrontal cortex in decision-making and psychopathology. |
2010-08-05 |
2023-08-12 |
Not clear |
| R Elliott, Z Agnew, J F W Deaki. Hedonic and informational functions of the human orbitofrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 1. 2010-08-02. PMID:19435707. |
functional imaging studies have revealed roles for orbitofrontal cortex (ofc) in reward processing and decision making. |
2010-08-02 |
2023-08-12 |
human |
| Jonathan D Wallis, Steven W Kennerle. Heterogeneous reward signals in prefrontal cortex. Current opinion in neurobiology. vol 20. issue 2. 2010-08-02. PMID:20303739. |
neurons in orbitofrontal cortex (pfo) appear to be responsible for calculating the specific value of an expected reward, information that can help efficiently guide decision-making. |
2010-08-02 |
2023-08-12 |
Not clear |
| Young-Chul Jung, Jeonghun Ku, Kee Namkoong, Wonho Lee, Sun I Kim, Jae-Jin Ki. Human orbitofrontal-striatum functional connectivity modulates behavioral persistence. Neuroreport. vol 21. issue 7. 2010-07-09. PMID:20357688. |
this study examines the functional connectivity of the orbitofrontal cortex during a decision-making task using functional magnetic resonance imaging. |
2010-07-09 |
2023-08-12 |
human |
| Young-Chul Jung, Jeonghun Ku, Kee Namkoong, Wonho Lee, Sun I Kim, Jae-Jin Ki. Human orbitofrontal-striatum functional connectivity modulates behavioral persistence. Neuroreport. vol 21. issue 7. 2010-07-09. PMID:20357688. |
the strength of the functional connectivity observed between the medial orbitofrontal cortex and the nucleus accumbens was determined to be correlated with the number of persistent responses made during the decision-making task. |
2010-07-09 |
2023-08-12 |
human |
| Young-Chul Jung, Jeonghun Ku, Kee Namkoong, Wonho Lee, Sun I Kim, Jae-Jin Ki. Human orbitofrontal-striatum functional connectivity modulates behavioral persistence. Neuroreport. vol 21. issue 7. 2010-07-09. PMID:20357688. |
it is proposed that top-down control of the orbitofrontal cortex over the ventral striatum is a critical component underlying individual differences in decision making during uncertain conditions. |
2010-07-09 |
2023-08-12 |
human |
| A Verdejo-García, M Pérez-García, A Bechar. Emotion, decision-making and substance dependence: a somatic-marker model of addiction. Current neuropharmacology. vol 4. issue 1. 2010-06-10. PMID:18615136. |
similar to patients with orbitofrontal cortex lesions, substance dependent individuals (sdi) show signs of impairments in decision-making, characterised by a tendency to choose the immediate reward at the expense of severe negative future consequences. |
2010-06-10 |
2023-08-12 |
Not clear |
| Edmund T Rolls, Fabian Grabenhorst, Benjamin A Parri. Neural systems underlying decisions about affective odors. Journal of cognitive neuroscience. vol 22. issue 5. 2010-05-27. PMID:19320548. |
for comparison, the mid orbitofrontal cortex (ofc) had activations related not to decision-making but to subjective pleasantness ratings, providing a continuous representation of affective value. |
2010-05-27 |
2023-08-12 |
Not clear |
| Marion Larquet, Giorgio Coricelli, Gaëlle Opolczynski, Florence Thibau. Impaired decision making in schizophrenia and orbitofrontal cortex lesion patients. Schizophrenia research. vol 116. issue 2-3. 2010-04-13. PMID:20022219. |
impaired decision making in schizophrenia and orbitofrontal cortex lesion patients. |
2010-04-13 |
2023-08-12 |
Not clear |
| Marion Larquet, Giorgio Coricelli, Gaëlle Opolczynski, Florence Thibau. Impaired decision making in schizophrenia and orbitofrontal cortex lesion patients. Schizophrenia research. vol 116. issue 2-3. 2010-04-13. PMID:20022219. |
the aim of this study was to examine impaired decision making in patients with schizophrenia and in patients with orbitofrontal cortex lesions. |
2010-04-13 |
2023-08-12 |
Not clear |
| Mark E Walton, Timothy E J Behrens, Mark J Buckley, Peter H Rudebeck, Matthew F S Rushwort. Separable learning systems in the macaque brain and the role of orbitofrontal cortex in contingent learning. Neuron. vol 65. issue 6. 2010-04-12. PMID:20346766. |
orbitofrontal cortex (ofc) is widely held to be critical for flexibility in decision-making when established choice values change. |
2010-04-12 |
2023-08-12 |
monkey |
| David H Zal. Orbitofrontal cortex contributions to food selection and decision making. Annals of behavioral medicine : a publication of the Society of Behavioral Medicine. vol 38 Suppl 1. 2010-04-09. PMID:19787309. |
orbitofrontal cortex contributions to food selection and decision making. |
2010-04-09 |
2023-08-12 |
Not clear |
| Heather C Lasseter, Donna R Ramirez, Xiaohu Xie, Rita A Fuch. Involvement of the lateral orbitofrontal cortex in drug context-induced reinstatement of cocaine-seeking behavior in rats. The European journal of neuroscience. vol 30. issue 7. 2010-01-18. PMID:19769591. |
orbitofrontal cortex (ofc) damage produces impaired decision-making, impulsivity and perseveration and potentially contributes to compulsive drug seeking in cocaine users. |
2010-01-18 |
2023-08-12 |
rat |
| Jian Li, Erte Xiao, Daniel Houser, P Read Montagu. Neural responses to sanction threats in two-party economic exchange. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 39. 2009-12-28. PMID:19805382. |
using a modified trust game, we found that trustees reciprocate relatively less when facing sanction threats, and that the presence of sanctions significantly reduces trustee's brain activities involved in social reward valuation [in the ventromedial prefrontal cortex (vmpfc), lateral orbitofrontal cortex, and amygdala] while it simultaneously increases brain activities in the parietal cortex, which has been implicated in rational decision making. |
2009-12-28 |
2023-08-12 |
Not clear |
| Charlotte A Boettiger, Elizabeth A Kelley, Jennifer M Mitchell, Mark D'Esposito, Howard L Field. Now or Later? An fMRI study of the effects of endogenous opioid blockade on a decision-making network. Pharmacology, biochemistry, and behavior. vol 93. issue 3. 2009-09-16. PMID:19258022. |
exploratory analyses identified additional loci where bold signal during decision-making was enhanced (left orbitofrontal cortex, left inferior temporal gyrus, and cerebellum) or reduced (right superior temporal pole) by ntx. |
2009-09-16 |
2023-08-12 |
human |
| M Pais-Vieira, M M Mendes-Pinto, D Lima, V Galhard. Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19362121. |
prefrontal areas such as the orbitofrontal cortex (ofc) have been shown to play a major role in performance on ambiguous decision-making tasks with substantial risk component, broadly named as "gambling tasks." |
2009-08-24 |
2023-08-12 |
human |
| Melissa T Buelow, Julie A Suh. Construct validity of the Iowa Gambling Task. Neuropsychology review. vol 19. issue 1. 2009-08-20. PMID:19194801. |
the iowa gambling task (igt) was created to assess real-world decision making in a laboratory setting and has been applied to various clinical populations (i.e., substance abuse, schizophrenia, pathological gamblers) outside those with orbitofrontal cortex damage, for whom it was originally developed. |
2009-08-20 |
2023-08-12 |
Not clear |
| S Prakash, E Ambrosio, L F Alguacil, N Del Olm. Genetic differences in hippocampal synaptic plasticity. Neuroscience. vol 161. issue 2. 2009-08-19. PMID:19336250. |
physiol rev 84:87-136] that contributes to maladaptive learning in drug addiction [schoenbaum g, roesch mr, stalnaker ta (2006) orbitofrontal cortex, decision-making and drug addiction. |
2009-08-19 |
2023-08-12 |
human |