All Relations between fear conditioning paradigm and amygdala

Publication Sentence Publish Date Extraction Date Species
Anna M Kaźmierowska, Mateusz Kostecki, Michał Szczepanik, Tomasz Nikolaev, Adam Hamed, Jarosław M Michałowski, Marek Wypych, Artur Marchewka, Ewelina Knapsk. Rats respond to aversive emotional arousal of human handlers with the activation of the basolateral and central amygdala. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 46. 2023-11-07. PMID:37934822. here, we report that when rats interact with a human caregiver who had recently undergone fear conditioning, they show risk assessment behavior and enhanced amygdala activation. 2023-11-07 2023-11-20 human
Ilaria Bertocchi, Florbela Rocha-Almeida, María Teresa Romero-Barragán, Marco Cambiaghi, Alejandro Carretero-Guillén, Paolo Botta, Godwin K Dogbevia, Mario Treviño, Paolo Mele, Alessandra Oberto, Matthew E Larkum, Agnes Gruart, Rolf Sprengel, José Maria Delgado-García, Mazahir T Hasa. Pre- and postsynaptic N-methyl-D-aspartate receptors are required for sequential printing of fear memory engrams. iScience. vol 26. issue 11. 2023-10-26. PMID:37876798. with advanced genetic methods, we combinatorially blocked presynaptic output and manipulated n-methyl-d-aspartate receptor (nmdar) in the basolateral amygdala (bla) and medial prefrontal cortex (mpfc) before and after cued fear conditioning. 2023-10-26 2023-11-08 Not clear
Megha Sehgal, Vanessa E Ehlers, James R Moye. Synaptic and intrinsic plasticity within overlapping lateral amygdala ensembles following fear conditioning. Frontiers in cellular neuroscience. vol 17. 2023-10-26. PMID:37876914. synaptic and intrinsic plasticity within overlapping lateral amygdala ensembles following fear conditioning. 2023-10-26 2023-11-08 Not clear
Hannah Hochgerner, Shelly Singh, Muhammad Tibi, Zhige Lin, Niv Skarbianskis, Inbal Admati, Osnat Ophir, Nuphar Reinhardt, Shai Netser, Shlomo Wagner, Amit Zeise. Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning. Nature neuroscience. 2023-10-26. PMID:37884748. neuronal types in the mouse amygdala and their transcriptional response to fear conditioning. 2023-10-26 2023-11-08 mouse
Matthew T Rich, Samantha J Worobey, Sharvari Mankame, Zhiping P Pang, Sarah E Swinford-Jackson, R Christopher Pierc. Sex-dependent fear memory impairment in cocaine-sired rat offspring. Science advances. vol 9. issue 42. 2023-10-21. PMID:37851809. long-term potentiation (ltp) was robust in the basolateral amygdala (bla), which encodes fear conditioning, of female offspring but was completely absent in male offspring of cocaine-exposed sires. 2023-10-21 2023-11-08 rat
K S Zimmermann, R Richardson, K D Bake. Developmental Changes in Functional Connectivity between the Prefrontal Cortex and Amygdala following Fear Extinction. Neurobiology of learning and memory. 2023-10-21. PMID:37865263. the retrograde tracer fluorogold was infused into the amygdala of postnatal day (p)22-23 (juvenile), p31-32 (adolescent), or ≥p69 (adult) rats, which were then exposed to fear conditioning and extinction training. 2023-10-21 2023-11-08 rat
Christine Stubbendorff, Ed Hale, Tobias Bast, Helen J Cassaday, Stephen J Martin, Sopapun Suwansawang, David M Halliday, Carl W Stevenso. Dopamine D1-like receptors modulate synchronized oscillations in the hippocampal-prefrontal-amygdala circuit in contextual fear. Scientific reports. vol 13. issue 1. 2023-10-17. PMID:37848657. contextual fear conditioning (cfc) is mediated by a neural circuit that includes the hippocampus, prefrontal cortex, and amygdala, but the neurophysiological mechanisms underlying the regulation of cfc by neuromodulators remain unclear. 2023-10-17 2023-11-08 rat
Thays B Santos, Juliana C Kramer-Soares, Cesar A O Coelho, Maria G M Oliveir. Temporal association activates projections from the perirhinal cortex and ventral CA1 to the prelimbic cortex and from the prelimbic cortex to the basolateral amygdala. Cerebral cortex (New York, N.Y. : 1991). 2023-10-12. PMID:37823340. both fear conditioning activated ventral ca1 and lateral entorhinal cortex neurons projecting to basolateral amygdala and basolateral amygdala neurons projecting to prelimbic cortex. 2023-10-12 2023-10-15 Not clear
Daniela Laricchiuta, Juliette Gimenez, Giuseppe Sciamanna, Andrea Termine, Carlo Fabrizio, Francesco Della Valle, Silvia Caioli, Luana Saba, Marco De Bardi, Francesca Balsamo, Anna Panuccio, Noemi Passarello, Anna Mattioni, Elisa Bisicchia, Cristina Zona, Valerio Orlando, Laura Petrosin. Synaptic and transcriptomic features of cortical and amygdala pyramidal neurons predict inefficient fear extinction. Cell reports. vol 42. issue 9. 2023-09-01. PMID:37656620. we find that, already before fear conditioning, specific morphological, electrophysiological, and transcriptomic patterns of cortical and amygdala pyramidal neurons predispose to fear-related disorders. 2023-09-01 2023-09-07 mouse
Tuval Keidar, Matthew J Williams-Spooner, Francesca S Wong, R Frederick Westbrook, Nathan M Holme. NMDA receptors in the basolateral amygdala complex are engaged for Pavlovian fear conditioning when an animal's predictions about danger are in error. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-08-22. PMID:37607821. nmda receptors in the basolateral amygdala complex are engaged for pavlovian fear conditioning when an animal's predictions about danger are in error. 2023-08-22 2023-09-07 Not clear
Joongkyu Park, Coralie Berthoux, Erika Hoyos-Ramirez, Lili Shan, Megumi Morimoto-Tomita, Yixiang Wang, Pablo E Castillo, Susumu Tomit. Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior. Cell reports. vol 42. issue 8. 2023-07-20. PMID:37471228. we use this tool to examine the specific role of synaptic ampar potentiation in amygdala neurons that are activated by fear conditioning. 2023-07-20 2023-08-14 Not clear
Greg Glickert, Ben Latimer, Pankaj Sah, Satish S Nai. Reverse engineering information processing in lateral amygdala during auditory tones. International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering. vol 2023. 2023-06-27. PMID:37366393. learning in the mammalian lateral amygdala (la) during auditory fear conditioning (tone - foot shock pairing), one form of associative learning, requires n-methyl-d-aspartate (nmda) receptor-dependent plasticity. 2023-06-27 2023-08-14 Not clear
Austin M Adkins, Emily M Colby, Woong-Ki Kim, Laurie L Wellman, Larry D Sanfor. Stressor control and regional inflammatory responses in the brain: regulation by the basolateral amygdala. Journal of neuroinflammation. vol 20. issue 1. 2023-05-27. PMID:37244986. we have also demonstrated that the basolateral amygdala (bla) regulates stress- and fear memory-induced alterations in sleep, and that differential sleep and immune responses in the brain to es and is appear to be integrated during fear conditioning and then reproduced by fear memory recall. 2023-05-27 2023-08-14 mouse
Kayla Farrell, Madeline Musaus, Aubrey Auerbach, Shaghayegh Navabpour, W Keith Ray, Richard F Helm, Timothy J Jarom. Proteasome-independent K63 polyubiquitination selectively regulates ATP levels and proteasome activity during fear memory formation in the female amygdala. Molecular psychiatry. 2023-05-17. PMID:37198264. only females had increased levels of k63-polyubiquitination targeting in the amygdala following fear conditioning, which targeted proteins involved in atp synthesis and proteasome function. 2023-05-17 2023-08-14 rat
Kylie A Huckleberry, Roberto Calitri, Anna J Li, Mackenna Mejdell, Ashna Singh, Vasvi Bhutani, Mikaela A Laine, Andrei S Nastase, Maria Morena, Matthew N Hill, Rebecca M Shansk. CB1R blockade unmasks TRPV1-mediated contextual fear generalization in female, but not male rats. bioRxiv : the preprint server for biology. 2023-04-24. PMID:37090594. fear conditioning elicited increased vhip aea levels in females only, and in both sexes, cb1r expression around vhip efferents targeting the basolateral amygdala (bla) was twice that at neighboring vhip neurons. 2023-04-24 2023-08-14 rat
Bruno José Moraes, Oliver Hard. Specific behaviors during auditory fear conditioning and postsynaptic expression of AMPA receptors in the basolateral amygdala predict interindividual differences in fear generalization in male rats. Learning & memory (Cold Spring Harbor, N.Y.). vol 30. issue 4. 2023-04-14. PMID:37059464. specific behaviors during auditory fear conditioning and postsynaptic expression of ampa receptors in the basolateral amygdala predict interindividual differences in fear generalization in male rats. 2023-04-14 2023-08-14 human
Francisca Silva, Gianluca Masella, Maria Francisca Madeira, Carlos B Duarte, Mónica Santo. TrkC Intracellular Signalling in the Brain Fear Network During the Formation of a Contextual Fear Memory. Molecular neurobiology. 2023-03-07. PMID:36882590. here, we put wild-type c57bl/6j mice through a contextual fear conditioning paradigm in order to characterize trkc activation and expression in the main brain regions involved in (learned) fear - amygdala, hippocampus, and prefrontal cortex - during the formation of a fear memory. 2023-03-07 2023-08-14 mouse
Thays Brenner Santos, Juliana Carlota Kramer-Soares, Maria Gabriela Menezes Oliveir. Contextual fear conditioning with a time interval induces CREB phosphorylation in the dorsal hippocampus and amygdala nuclei that depend on prelimbic cortex activity. Hippocampus. 2023-02-27. PMID:36847108. for this, we observed in wistar rats the effect of pre-training pl inactivation by muscimol in creb (camp response element-binding protein) phosphorylation, which is essential for memory consolidation, in subdivisions of the medial prefrontal cortex (mpfc), hippocampus, and amygdala 3 h after the training in the contextual fear conditioning (cfc) or cfc with 5-s interval (cfc-5s), fear associations without or with an interval between the cs and us, respectively. 2023-02-27 2023-08-14 rat
Junhui Huang, Fei Xu, Liping Yang, Lina Tuolihong, Xiaoyu Wang, Zibo Du, Yiqi Zhang, Xuanlin Yin, Yingjun Li, Kangrong Lu, Wanshan Wan. Involvement of the GABAergic system in PTSD and its therapeutic significance. Frontiers in molecular neuroscience. vol 16. 2023-02-23. PMID:36818657. the inhibition of gaba neurons, especially in the amygdala, is crucial for the precise regulation of the consolidation, expression, and extinction of fear conditioning. 2023-02-23 2023-08-14 Not clear
Rami El Matine, Judith C Kreutzmann, Markus Fend. Chronic unilateral inhibition of GABA synthesis in the amygdala increases specificity of conditioned fear in a discriminative fear conditioning paradigm in rats. Progress in neuro-psychopharmacology & biological psychiatry. 2023-02-15. PMID:36792003. chronic unilateral inhibition of gaba synthesis in the amygdala increases specificity of conditioned fear in a discriminative fear conditioning paradigm in rats. 2023-02-15 2023-08-14 rat