| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wendi S Neckameyer, Parag Bhat. Neurotrophic actions of dopamine on the development of a serotonergic feeding circuit in Drosophila melanogaster. BMC neuroscience. vol 13. 2012-09-27. PMID:22413901. |
since dopamine can function in central nervous system development, separate from its role as a neurotransmitter, the role of neuronal dopamine was assessed on the development, and mature function, of the 5-ht larval feeding circuit. |
2012-09-27 |
2023-08-12 |
drosophila_melanogaster |
| Jessica Santollo, Dachun Yao, Genevieve Neal-Perry, Anne M Etge. Middle-aged female rats retain sensitivity to the anorexigenic effect of exogenous estradiol. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22522024. |
next, we investigated whether genes that mediate the estrogenic inhibition of food intake are similarly responsive to e2 by measuring gene expression of the anorexigenic genes corticotropin-releasing hormone (crh), proopiomelanocortin (pomc), the long form of the leptin receptor (lepr) and serotonin 2c receptors (5ht2cr) and the orexigenic genes agouti-related peptide (agrp), neuropeptide y (npy), prepromelanin-concentrating hormone (pmch) and orexin in the hypothalamus of young and middle-aged ovx rats treated with e2. |
2012-09-27 |
2023-08-12 |
rat |
| L Brunetti, L Recinella, C Di Nisio, A Chiavaroli, S Leone, C Ferrante, G Orlando, M Vacc. Effects of visfatin/PBEF/NAMPT on feeding behaviour and hypothalamic neuromodulators in the rat. Journal of biological regulators and homeostatic agents. vol 26. issue 2. 2012-09-21. PMID:22824756. |
food intake was recorded 1, 2 and 24 h following injection, and either dopamine (da), norepinephrine (ne), serotonin (5-hydroxytryptamine, 5-ht) or peptide gene expression were evaluated 2 and 24 h after visfatin/pbef/nampt administration. |
2012-09-21 |
2023-08-12 |
rat |
| Maria J Arranz, Margarita Rivera, Janet C Munr. Pharmacogenetics of response to antipsychotics in patients with schizophrenia. CNS drugs. vol 25. issue 11. 2012-09-05. PMID:22054119. |
serotonin influences the control of feeding behaviour and has been hypothesized to have a role in the development of antipsychotic-induced weight gain. |
2012-09-05 |
2023-08-12 |
human |
| Harriët Schellekens, Gerard Clarke, Ian B Jeffery, Timothy G Dinan, John F Crya. Dynamic 5-HT2C receptor editing in a mouse model of obesity. PloS one. vol 7. issue 3. 2012-08-20. PMID:22448217. |
recently, it has been shown that feeding behaviour and fat mass are altered when the 5-ht(2c) receptor rna is fully edited, suggesting a potential role for 5-ht(2c) editing in obesity. |
2012-08-20 |
2023-08-12 |
mouse |
| Harriët Schellekens, Gerard Clarke, Ian B Jeffery, Timothy G Dinan, John F Crya. Dynamic 5-HT2C receptor editing in a mouse model of obesity. PloS one. vol 7. issue 3. 2012-08-20. PMID:22448217. |
the present studies investigate the expression of serotonin receptors involved in central regulation of food intake, appetite and energy expenditure, with particular focus on the level of 5-ht(2c) receptor editing. |
2012-08-20 |
2023-08-12 |
mouse |
| T A Roepke, A W Smith, O K Rønnekleiv, M J Kell. Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons. American journal of physiology. Endocrinology and metabolism. vol 302. issue 11. 2012-08-03. PMID:22436698. |
serotonin increases pomc activity and reduces feeding behavior via serotonion [5-hydroxytryptamine (5-ht)] receptors by modulating k(+) currents. |
2012-08-03 |
2023-08-12 |
mouse |
| T A Roepke, A W Smith, O K Rønnekleiv, M J Kell. Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons. American journal of physiology. Endocrinology and metabolism. vol 302. issue 11. 2012-08-03. PMID:22436698. |
collectively, these data suggest that although m-current expression does not differ between fed and fasted states in pomc neurons, serotonin inhibits the m-current via activation of 5-ht(2c) receptors to increase pomc neuronal excitability and, subsequently, reduce food intake. |
2012-08-03 |
2023-08-12 |
mouse |
| Xiaoning Chen, Kara J Margolis, Michael D Gershon, Gary J Schwartz, Ji Y Sz. Reduced serotonin reuptake transporter (SERT) function causes insulin resistance and hepatic steatosis independent of food intake. PloS one. vol 7. issue 3. 2012-08-02. PMID:22412882. |
reduced serotonin reuptake transporter (sert) function causes insulin resistance and hepatic steatosis independent of food intake. |
2012-08-02 |
2023-08-12 |
mouse |
| Xiaoning Chen, Kara J Margolis, Michael D Gershon, Gary J Schwartz, Ji Y Sz. Reduced serotonin reuptake transporter (SERT) function causes insulin resistance and hepatic steatosis independent of food intake. PloS one. vol 7. issue 3. 2012-08-02. PMID:22412882. |
antidepressants, such as selectively serotonin reuptake inhibitors (ssris), that block sert function are known to affect food intake and body weight. |
2012-08-02 |
2023-08-12 |
mouse |
| Christina Sørensen, Göran E Nilsson, Cliff H Summers, Øyvind Øverl. Social stress reduces forebrain cell proliferation in rainbow trout (Oncorhynchus mykiss). Behavioural brain research. vol 227. issue 2. 2012-07-19. PMID:21291915. |
after 4 days of interaction, socially subordinate fish displayed common signs of chronic stress including reduced feeding behaviour, elevated plasma cortisol levels, and up-regulated brain stem 5-ht activity. |
2012-07-19 |
2023-08-12 |
Not clear |
| Melissa Lingis, Elaine Richards, Dana Perrone, Maureen Keller-Woo. Serotonergic effects on feeding, but not hypothalamus-pituitary-adrenal secretion, are altered in ovine pregnancy. American journal of physiology. Endocrinology and metabolism. vol 302. issue 10. 2012-07-17. PMID:22374755. |
in addition, we found a reduced ability of serotonin to inhibit feeding in the pregnant ewes, consistent with a reduction in anorexic mechanisms in the pregnant state. |
2012-07-17 |
2023-08-12 |
human |
| Paul J Currie, Aaisha Mirza, Lindsey M Dono, Catherine S John, Daniel G Wal. Anorexigenic action of nitric oxide synthase inhibition in the raphe nuclei. Neuroreport. vol 22. issue 14. 2012-06-04. PMID:21817925. |
the inhibitory effects of l-name and 7-ni on eating elicited by 8-oh-dpat further suggest that nitric oxide and 5-ht systems interact in the control of food intake. |
2012-06-04 |
2023-08-12 |
rat |
| Bruno Campos, Benjamín Piña, Carlos Barata . Mechanisms of action of selective serotonin reuptake inhibitors in Daphnia magna. Environmental science & technology. vol 46. issue 5. 2012-05-29. PMID:22324381. |
d. magna reproduction tests, respiration, feeding, and survival-starvation assays and studies of lipids, proteins, and carbohydrate levels of unexposed and exposed females to the ssri fluoxetine and fluvoxamine and the 5-ht serotonin receptor antagonist cyproheptadine were conducted. |
2012-05-29 |
2023-08-12 |
Not clear |
| Ioannis Papazoglou, Flavien Berthou, Nicolas Vicaire, Claude Rouch, Eirini M Markaki, Danielle Bailbe, Bernard Portha, Mohammed Taouis, Kyriaki Gerozissi. Hypothalamic serotonin-insulin signaling cross-talk and alterations in a type 2 diabetic model. Molecular and cellular endocrinology. vol 350. issue 1. 2012-05-18. PMID:22209745. |
finally, in response to food intake, hypothalamic serotonin release was reduced in gk rats, indicating impaired responsiveness of this neurotransmitter. |
2012-05-18 |
2023-08-12 |
rat |
| Jason C G Halford, Joanne A Harrol. 5-HT(2C) receptor agonists and the control of appetite. Handbook of experimental pharmacology. issue 209. 2012-04-25. PMID:22249823. |
5-ht drugs reduce food intake in rodents in a manner consistent with an enhancement of satiety. |
2012-04-25 |
2023-08-12 |
Not clear |
| Tomotaka Murotani, Tomoko Ishizuka, Yuka Isogawa, Michitaka Karashima, Atsushi Yamatodan. Possible involvement of serotonin 5-HT2 receptor in the regulation of feeding behavior through the histaminergic system. Neuropharmacology. vol 61. issue 1-2. 2012-04-17. PMID:21514311. |
possible involvement of serotonin 5-ht2 receptor in the regulation of feeding behavior through the histaminergic system. |
2012-04-17 |
2023-08-12 |
mouse |
| Tomotaka Murotani, Tomoko Ishizuka, Yuka Isogawa, Michitaka Karashima, Atsushi Yamatodan. Possible involvement of serotonin 5-HT2 receptor in the regulation of feeding behavior through the histaminergic system. Neuropharmacology. vol 61. issue 1-2. 2012-04-17. PMID:21514311. |
some atypical antipsychotics like risperidone and aripiprazole are known to affect feeding behavior and to antagonize the serotonin (5-ht) receptor subtypes. |
2012-04-17 |
2023-08-12 |
mouse |
| Tomotaka Murotani, Tomoko Ishizuka, Yuka Isogawa, Michitaka Karashima, Atsushi Yamatodan. Possible involvement of serotonin 5-HT2 receptor in the regulation of feeding behavior through the histaminergic system. Neuropharmacology. vol 61. issue 1-2. 2012-04-17. PMID:21514311. |
), which have binding affinities to 5-ht(1a, 2a, 2b) and (2c) receptors decreased food intake in c57bl/6n mice with concomitant increase of hypothalamic histamine release. |
2012-04-17 |
2023-08-12 |
mouse |
| Makoto Hamao, Hisashi Matsuda, Seikou Nakamura, Souichi Nakashima, Shunsuke Semura, Saori Maekubo, Sachiyo Wakasugi, Masayuki Yoshikaw. Anti-obesity effects of the methanolic extract and chakasaponins from the flower buds of Camellia sinensis in mice. Bioorganic & medicinal chemistry. vol 19. issue 20. 2012-03-29. PMID:21925888. |
these findings suggested that the active saponins suppressed the appetite signals in the hypothalamus through stimulation of the capsaicin-sensitive sensory nerves, probably vagal afferent nerves, or enhancement of 5-ht release from the ilea, leading to reduced food intake and body weight gain. |
2012-03-29 |
2023-08-12 |
mouse |