| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pin Yang, Ke-li Dong, Wang-yuan Zen. [Effect of yizhi jiannao granule on the behavior and neuron apoptosis in SAMP/8 mice]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 31. issue 1. 2006-10-13. PMID:16562676. |
to investigate the effect of yizhi jiannao granule concentration fluid (ycf) on the behavior, the apoptosis rate of hippocampus neuron and the expression of apoptosis gene bcl-2, bax in senescence accelerated mice senile-prone/8 (samp/8), and to discuss some mechanism of traditional chinese medicine ycf in improving the capability of learning and memory. |
2006-10-13 |
2023-08-12 |
mouse |
| Zheng Feng, Jun-tian Zhan. Long-term melatonin or 17beta-estradiol supplementation alleviates oxidative stress in ovariectomized adult rats. Free radical biology & medicine. vol 39. issue 2. 2005-10-24. PMID:15964511. |
our previous results indicated that melatonin improved learning and memory deficits in the transgenic mouse model of alzheimer's disease (ad) and ovariectomized (ovx) rats by improving cholinergic nerve system dysfunction, preventing apoptosis. |
2005-10-24 |
2023-08-12 |
mouse |
| Christian Gianinazzi, Denis Grandgirard, Hans Imboden, Lotti Egger, Damian N Meli, Yoeng-Delphine Bifrare, Philipp C Joss, Martin G Täuber, Christoph Borner, Stephen L Lei. Caspase-3 mediates hippocampal apoptosis in pneumococcal meningitis. Acta neuropathologica. vol 105. issue 5. 2003-06-06. PMID:12677451. |
bacterial meningitis causes neuronal apoptosis in the hippocampal dentate gyrus, which is associated with learning and memory impairments after cured disease. |
2003-06-06 |
2023-08-12 |
rat |
| C Lu, W Fu, M P Mattso. Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: implications for neurological side effects of cancer therapy and neurodegenerative disorders. Neurobiology of disease. vol 8. issue 2. 2001-07-12. PMID:11300717. |
the excitatory neurotransmitter glutamate plays central roles in the activation of neurons and in processes such as learning and memory, but overactivation of ionotropic glutamate receptors can induce either apoptosis or necrosis. |
2001-07-12 |
2023-08-12 |
Not clear |
| C D Albright, C B Friedrich, E C Brown, M H Mar, S H Zeise. Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain research. Developmental brain research. vol 115. issue 2. 1999-09-13. PMID:10407130. |
these results show that dietary choline availability during pregnancy alters the timing of mitosis, apoptosis and the early commitment to neuronal differentiation by progenitor cells in regions of the fetal brain septum, as well as hippocampus, two brain regions known to be associated with learning and memory. |
1999-09-13 |
2023-08-12 |
rat |