| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karin Boekhoorn, Dick Terwel, Barbara Biemans, Peter Borghgraef, Olof Wiegert, Ger J A Ramakers, Koos de Vos, Harm Krugers, Takami Tomiyama, Hiroshi Mori, Marian Joels, Fred van Leuven, Paul J Lucasse. Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 13. 2006-04-18. PMID:16571759. |
the data demonstrate that learning and memory processes in the hippocampus of young tau-p301l mice are not impaired and actually improved in the absence of marked phosphorylation of human tau. |
2006-04-18 |
2023-08-12 |
mouse |
| Andreas Mershin, Elias Pavlopoulos, Olivia Fitch, Brittany C Braden, Dimitri V Nanopoulos, Efthimios M C Skoulaki. Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 3. 2004-08-25. PMID:15169857. |
learning and memory deficits upon tau accumulation in drosophila mushroom body neurons. |
2004-08-25 |
2023-08-12 |
drosophila_melanogaster |
| Andreas Mershin, Elias Pavlopoulos, Olivia Fitch, Brittany C Braden, Dimitri V Nanopoulos, Efthimios M C Skoulaki. Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 3. 2004-08-25. PMID:15169857. |
we report that directed expression of wild-type vertebrate and drosophila tau in adult mushroom body neurons, centers for olfactory learning and memory in drosophila, strongly compromised associative olfactory learning and memory, but olfactory conditioning-relevant osmotactic and mechanosensory responses remained intact. |
2004-08-25 |
2023-08-12 |
drosophila_melanogaster |
| Jin-dong Hu, Qiu-hua Gao, Deng-guang Yu, Xiong-tao X. [The improvement of taurine in learning and memory ability of rats exposed to lead]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases. vol 21. issue 6. 2004-05-27. PMID:14761348. |
to investigate the improvement of taurine (tau) in learning and memory ability of rats exposed to lead. |
2004-05-27 |
2023-08-12 |
rat |
| L L. [An animal model of non-hereditary Alzheimer's disease and its behavioral and pathologic changes]. Sheng li ke xue jin zhan [Progress in physiology]. vol 28. issue 4. 2001-03-01. PMID:11038683. |
results showed: (1) loss of learning and memory ability; (2) occurrence of necrotic granules in cytoplasm and inclusion in axon hillock; accumulation of necrotic cell, and formation of sps under light microscope; (3) accumulation of microtubules and formation of inclusion, increase of lysosome and edema and vacuolation of neurons and neuroterminals under electron microscopy; (4) decrease of synaptic density; (5) sharp decrease of ache (acetylcholinesterase) positive fibers and neurons shown by immunocytochemical staining; (6) overexpression of beta ap and tau protein. |
2001-03-01 |
2023-08-12 |
Not clear |
| L Genis, Y Chen, E Shohami, D M Michaelso. Tau hyperphosphorylation in apolipoprotein E-deficient and control mice after closed head injury. Journal of neuroscience research. vol 60. issue 4. 2000-06-23. PMID:10797559. |
apolipoprotein e (apoe)-deficient mice have learning and memory impairments that are associated with specific neurochemical changes and hyperphosphorylation of distinct epitopes of the cytoskeletal protein tau. |
2000-06-23 |
2023-08-12 |
mouse |
| K Hsia. Transgenic mice expressing Alzheimer amyloid precursor proteins. Experimental gerontology. vol 33. issue 7-8. 1999-04-15. PMID:9951631. |
these features, which are present to various degrees in different lines of mice, include age-related impairment in learning and memory, neuronal loss, gliosis, neuritic changes, amyloid deposition, and abnormal tau phosphorylation. |
1999-04-15 |
2023-08-12 |
mouse |