| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clark W Bird, Devin H Taylor, Natalie J Pinkowski, G Jill Chavez, C Fernando Valenzuel. Long-term Reductions in the Population of GABAergic Interneurons in the Mouse Hippocampus following Developmental Ethanol Exposure. Neuroscience vol 383 issue 2019 29753864 |
little evidence exists, however, describing the long-term impact of fetal alcohol exposure on survival of interneurons within the hippocampal formation, which is critical for learning and memory processes that are impaired in individuals with fasds. |
2019-03-07 |
2023-01-26 |
mouse |
| Roberto O Soares, Everton Horiquini-Barbosa, Sebasti\\xc3\\xa3o S Almeida, Jo\\xc3\\xa3o-Jos\\xc3\\xa9 Lacha. Environmental enrichment protects spatial learning and hippocampal neurons from the long-lasting effects of protein malnutrition early in life. Behavioural brain research vol 335 issue 2018 28797597 |
as early protein malnutrition has a critically long-lasting impact on the hippocampal formation and its role in learning and memory, and environmental enrichment has demonstrated great success in ameliorating functional deficits, here we ask whether exposure to an enriched environment could be employed to prevent spatial memory impairment and neuroanatomical changes in the hippocampus of adult rats maintained on a protein deficient diet during brain development (p0-p35). |
2018-05-22 |
2023-01-26 |
rat |
| Muneaki Miyata, Tomohiko Maruo, Aika Kaito, Shujie Wang, Hideaki Yamamoto, Takeshi Fujiwara, Akira Mizoguchi, Kenji Mandai, Yoshimi Taka. Roles of afadin in the formation of the cellular architecture of the mouse hippocampus and dentate gyrus. Molecular and cellular neurosciences vol 79 issue 2018 28041940 |
the hippocampal formation with tightly packed neurons, mainly at the dentate gyrus, ca3, ca2, and ca1 regions, constitutes a one-way neural circuit, which is associated with learning and memory. |
2018-01-12 |
2023-01-26 |
mouse |
| Vijayakumar Kapgal, Neethi Prem, Preethi Hegde, T R Laxmi, Bindu M Kutt. Long term exposure to combination paradigm of environmental enrichment, physical exercise and diet reverses the spatial memory deficits and restores hippocampal neurogenesis in ventral subicular lesioned rats. Neurobiology of learning and memory vol 130 issue 2016 26851129 |
subiculum is an important structure of the hippocampal formation and plays an imperative role in spatial learning and memory functions. |
2016-12-30 |
2023-01-25 |
rat |
| Christine J Fontaine, Anna R Patten, Helle M Sickmann, Jennifer L Helfer, Brian R Christi. Effects of pre-natal alcohol exposure on hippocampal synaptic plasticity: Sex, age and methodological considerations. Neuroscience and biobehavioral reviews vol 64 issue 2016 26906760 |
the hippocampal formation, a brain region implicated in learning and memory, is highly susceptible to the effects of developmental alcohol exposure. |
2016-12-27 |
2023-01-25 |
Not clear |
| Jie Yang, Ying Pan, Xuejing Li, Xianying Wan. Atorvastatin attenuates cognitive deficits through Akt1/caspase-3 signaling pathway in ischemic stroke. Brain research vol 1629 issue 2016 26597376 |
neuronal damage in the hippocampal formation is more sensitive to ischemic stimulation and easily injured, causing severe learning and memory impairment. |
2016-09-22 |
2023-01-25 |
rat |
| Ting-Ting Huang, David Leu, Yani Zo. Oxidative stress and redox regulation on hippocampal-dependent cognitive functions. Archives of biochemistry and biophysics vol 576 issue 2015 25797440 |
hippocampal formation is exquisitely sensitive to patho-physiological changes, and reduced antioxidant capacity and exposure to low dose irradiation can significantly impede hippocampal-dependent functions of learning and memory by reducing the production of new neurons and alter dendritic structures in the hippocampus. |
2015-08-10 |
2023-01-25 |
mouse |
| Bao-Ying Hu, Xian-Jin Liu, Ren Qiang, Zheng-Lin Jiang, Li-Hua Xu, Guo-Hua Wang, Xia Li, Bin Pen. Treatment with ginseng total saponins improves the neurorestoration of rat after traumatic brain injury. Journal of ethnopharmacology vol 155 issue 2 2015 25046825 |
the present study aimed to investigate whether treatment with ginsenosides could facilitate nsc proliferation in the hippocampal formation after traumatic brain injury (tbi) and contribute to the recovery of neurological functions including learning and memory. |
2015-07-23 |
2023-01-25 |
rat |
| Josh M Morganti, Timothy D Jopson, Sharon Liu, Lara-Kirstie Riparip, Cristian K Guandique, Nalin Gupta, Adam R Ferguson, Susanna Ros. CCR2 antagonism alters brain macrophage polarization and ameliorates cognitive dysfunction induced by traumatic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 35 issue 2 2015 25589768 |
using cx3cr1(gfp/+)ccr2(rfp/+) reporter mice, we show that tbi initiated a temporally restricted accumulation of peripherally derived ccr2(+) macrophages, which were concentrated in the hippocampal formation, a region necessary for learning and memory. |
2015-04-07 |
2023-01-25 |
mouse |
| Andrea M Allan, Samantha L Goggin, Kevin K Caldwel. Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning. PloS one vol 9 issue 4 2015 24755652 |
in our mouse model of pae we recently reported deficits in hippocampal formation-dependent learning and memory and a dysregulation of hippocampal formation glucocorticoid receptor (gr) subcellular distribution. |
2015-01-20 |
2023-01-25 |
mouse |
| Xiangru Wen, Dashi Qi, Ying Sun, Xiaojing Huang, Fang Zhang, Jian Wu, Yanyan Fu, Kai Ma, Yang Du, Hongyan Dong, YongHai Liu, Hongzhi Liu, Yuanjian Son. H\\xe2\\x82\\x82S attenuates cognitive deficits through Akt1/JNK3 signaling pathway in ischemic stroke. Behavioural brain research vol 269 issue 2015 24768640 |
neuronal damage in the hippocampal formation which is more sensitive to ischemic stimulation and easily injured will cause severe learning and memory impairment. |
2015-01-15 |
2023-01-25 |
rat |
| Bruno Dietsche, Heidelore Backes, Davide Laneri, Thomas Weikert, Stephanie H Witt, Marcella Rietschel, Jens Sommer, Tilo Kircher, Axel Kru. The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study. NeuroImage vol 89 issue 2014 24269271 |
in the present study we investigated the impact of the cacna1c snp rs1006737 on the fractional anisotropy (fa) in the hippocampal formation as well as on verbal learning and memory in healthy individuals. |
2014-10-29 |
2023-01-25 |
Not clear |
| Jennifer L Helfer, Emily R White, Brian R Christi. Prenatal ethanol (EtOH) exposure alters the sensitivity of the adult dentate gyrus to acute EtOH exposure. Alcoholism, clinical and experimental research vol 38 issue 1 2014 23915337 |
the hippocampal formation, an area of the brain strongly linked with learning and memory, is particularly vulnerable to the teratogenic effects of etoh. |
2014-10-09 |
2023-01-25 |
Not clear |
| Alan N Francis, Larry J Seidman, Neeraj Tandon, Martha E Shenton, Heidi W Thermenos, Raquelle I Mesholam-Gately, Ludger T van Elst, Brunna Tuschen-Caffier, Lynn E DeLisi, Matcheri S Keshava. Reduced subicular subdivisions of the hippocampal formation and verbal declarative memory impairments in young relatives at risk for schizophrenia. Schizophrenia research vol 151 issue 1-3 2014 24144441 |
in this study, subdivisions of the hippocampal formation and their association with verbal and visual learning and memory were assessed in persons at familial high risk (fhr) for sz. |
2014-07-29 |
2023-01-25 |
human |
| Giuseppe Gangarossa, Sophie Longueville, Dimitri De Bundel, Julie Perroy, Denis Herv\\xc3\\xa9, Jean-Antoine Girault, Emmanuel Valjen. Characterization of dopamine D1 and D2 receptor-expressing neurons in the mouse hippocampus. Hippocampus vol 22 issue 12 2013 22777829 |
the hippocampal formation is part of an anatomical system critically involved in learning and memory. |
2013-06-27 |
2023-01-25 |
mouse |
| Dahua Lu, Lixin He, Wei Xiang, Wei-Min Ai, Ye Cao, Xiao-Sheng Wang, Aihua Pan, Xue-Gang Luo, Zhiyuan Li, Xiao-Xin Ya. Somal and dendritic development of human CA3 pyramidal neurons from midgestation to middle childhood: a quantitative Golgi study. Anatomical record (Hoboken, N.J. : 2007) vol 296 issue 1 2013 23152308 |
the ca3 area serves a key relay on the tri-synaptic loop of the hippocampal formation which supports multiple forms of mnemonic processing, especially spatial learning and memory. |
2013-06-13 |
2023-01-25 |
human |
| Jennifer L Helfer, Emily R White, Brian R Christi. Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. PloS one vol 7 issue 12 2013 23227262 |
the hippocampal formation, an area of the brain strongly linked with learning and memory, is particularly vulnerable to the teratogenic effects of ethanol. |
2013-05-21 |
2023-01-25 |
Not clear |
| Jennifer L Helfer, Emily R White, Brian R Christi. Enhanced deficits in long-term potentiation in the adult dentate gyrus with 2nd trimester ethanol consumption. PloS one vol 7 issue 12 2013 23227262 |
furthermore, these results allude to neural circuit malfunction within the hippocampal formation, perhaps relating to the learning and memory deficits observed in individuals with fetal alcohol spectrum disorders. |
2013-05-21 |
2023-01-25 |
Not clear |
| Marong Fang, Yifei Yin, Haohao Chen, Zhiying Hu, Henry Davies, Shucai Lin. Contribution of Rag1 to spatial memory ability in rats. Behavioural brain research vol 236 issue 1 2013 22964459 |
rag1 transcription is most apparent in regions of the postnatal brain with high neuronal cell density--the cerebellum and the hippocampal formation, both of which are relevant to learning and memory function. |
2013-04-23 |
2023-01-25 |
rat |
| Pawel Fidzinski, Matthias Wawra, Julia Bartsch, Uwe Heinemann, Joachim Beh. High-frequency stimulation of the temporoammonic pathway induces input-specific long-term potentiation in subicular bursting cells. Brain research vol 1430 issue 2012 22104348 |
the subiculum (sub) as a part of the hippocampal formation is thought to play a functional role in learning and memory. |
2012-09-07 |
2023-01-25 |
Not clear |