| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J Mizumori, A Kalyan. Age and experience-dependent representational reorganization during spatial learning. Neurobiology of aging. vol 18. issue 6. 1998-03-05. PMID:9461063. |
in the present experiment, after animals became familiar with the test environment and motor demands of performance on a radial maze, ca1 and hilar place cells were recorded as they learned a spatial memory task. |
1998-03-05 |
2023-08-12 |
rat |
| D A Rusakov, H A Davies, E Harrison, G Diana, G Richter-Levin, T V Bliss, M G Stewar. Ultrastructural synaptic correlates of spatial learning in rat hippocampus. Neuroscience. vol 80. issue 1. 1997-10-23. PMID:9252221. |
this finding indicates subtle changes in synaptic organization in area ca1 of the hippocampus following a learning experience, suggesting that spatial memory formation in mammalian hippocampus may involve topographical changes in local circuitry without synapse formation de novo. |
1997-10-23 |
2023-08-12 |
rat |
| S J Mizumori, A M Lavoie, A Kalyan. Redistribution of spatial representation in the hippocampus of aged rats performing a spatial memory task. Behavioral neuroscience. vol 110. issue 5. 1997-03-18. PMID:8919003. |
spatial correlates of hippocampal ca1 and hilar cells varied with task demand: ca1 cells of aged rats showed more spatially selective place fields, whereas hilar cells showed more diffuse location coding during spatial memory, and not forced-choice, tests. |
1997-03-18 |
2023-08-12 |
rat |
| J Z Tsien, P T Huerta, S Tonegaw. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell. vol 87. issue 7. 1997-02-03. PMID:8980238. |
the essential role of hippocampal ca1 nmda receptor-dependent synaptic plasticity in spatial memory. |
1997-02-03 |
2023-08-12 |
mouse |
| J Z Tsien, P T Huerta, S Tonegaw. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell. vol 87. issue 7. 1997-02-03. PMID:8980238. |
adult mice lack nmda receptor-mediated synaptic currents and long-term potentiation in the ca1 synapses and exhibit impaired spatial memory but unimpaired nonspatial learning. |
1997-02-03 |
2023-08-12 |
mouse |
| M Ohno, S Watanab. Ischemic tolerance to memory impairment associated with hippocampal neuronal damage after transient cerebral ischemia in rats. Brain research bulletin. vol 40. issue 3. 1996-11-29. PMID:8736585. |
these findings suggest that postischemic hippocampal ca1 neuronal damage does not affect retention of spatial memory acquired before ischemia, but produces a significant impairment of acquisition and subsequent reversal learning. |
1996-11-29 |
2023-08-12 |
rat |
| S I Deutsch, R B Rosse, C Morn, L Koetzner, J Mastropaol. Interference with nitric oxide production and action potentiates the antiseizure efficacy of flurazepam. Pharmacology, biochemistry, and behavior. vol 51. issue 1. 1995-08-22. PMID:7617724. |
nmda receptor antagonists cause neuronal toxicity, interfere with acquisition of spatial memory and induction of long-term potentiation in the hippocampal ca1 region, and precipitate psychoses in susceptible individuals. |
1995-08-22 |
2023-08-12 |
mouse |
| U Stäubli, F B X. Effects of 5-HT3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 3 Pt 2. 1995-04-17. PMID:7891179. |
the effects of ondansetron, a potent and selective antagonist of the 5-ht3 receptor, were examined on (1) frequency of the hippocampal theta rhythm, (2) induction of ltp in field ca1 of freely moving rats, and (3) retention of olfactory and spatial memory in tasks known to depend on an intact hippocampus. |
1995-04-17 |
2023-08-12 |
rat |
| S Nurse, D Corbet. Direct measurement of brain temperature during and after intraischemic hypothermia: correlation with behavioral, physiological, and histological endpoints. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 12. 1995-01-17. PMID:7996207. |
following a period of recovery, two independent measures were used to assess hippocampal function: (1) an open field test of spatial memory (assessment was made during the first 10 d after ischemia) and (2) measurement of evoked potentials from area ca1 in hippocampal slices (3 weeks after the ischemic episode). |
1995-01-17 |
2023-08-12 |
Not clear |
| S Nurse, D Corbet. Direct measurement of brain temperature during and after intraischemic hypothermia: correlation with behavioral, physiological, and histological endpoints. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 12. 1995-01-17. PMID:7996207. |
animals treated with hypothermia performed as well as sham-operated controls in a spatial memory task, had field potentials that were indistinguishable from normal animals and ca1 cells appeared normal when assessed histologically. |
1995-01-17 |
2023-08-12 |
Not clear |
| G M Olsen, J Scheel-Krüger, A Møller, L H Jense. Does neuronal damage of CA1 relate to spatial memory performance of rats subjected to transient forebrain ischemia? Acta neurologica Scandinavica. vol 89. issue 3. 1994-08-08. PMID:8030402. |
does neuronal damage of ca1 relate to spatial memory performance of rats subjected to transient forebrain ischemia? |
1994-08-08 |
2023-08-12 |
rat |
| G Richter-Levin, H Markram, M Sega. Spontaneous recovery of deficits in spatial memory and cholinergic potentiation of NMDA in CA1 neurons during chronic lithium treatment. Hippocampus. vol 2. issue 3. 1993-09-24. PMID:1339194. |
spontaneous recovery of deficits in spatial memory and cholinergic potentiation of nmda in ca1 neurons during chronic lithium treatment. |
1993-09-24 |
2023-08-11 |
rat |
| A M Kleschevnikov, R M Marchbank. Behavioral parameters of the spatial memory correlate with the potentiation of the population spike, but not with the population excitatory postsynaptic potential, of the CA1 region in rat hippocampal slices. Neuroscience letters. vol 152. issue 1-2. 1993-07-19. PMID:7685862. |
behavioral parameters of the spatial memory correlate with the potentiation of the population spike, but not with the population excitatory postsynaptic potential, of the ca1 region in rat hippocampal slices. |
1993-07-19 |
2023-08-12 |
rat |
| J C de la Torre, T Fortin, G A Park, K S Butler, P Kozlowski, B A Pappas, H de Socarraz, J K Saunders, M T Richar. Chronic cerebrovascular insufficiency induces dementia-like deficits in aged rats. Brain research. vol 582. issue 2. 1992-11-19. PMID:1327402. |
nine weeks after cvi, hippocampal cbf reductions, spatial memory impairment, spectroscopic-microimaging changes and ca1 sector cell damage continued to be observed in the aged animals but were resolved in the young rat brains. |
1992-11-19 |
2023-08-11 |
rat |
| S J Mizumori, K E Ward, A M Lavoi. Medial septal modulation of entorhinal single unit activity in anesthetized and freely moving rats. Brain research. vol 570. issue 1-2. 1992-07-31. PMID:1617411. |
reversible inactivation of the medial septal area results in a spatial memory impairment and selective disruption of hilar/ca3, but not ca1, location-specific discharge. |
1992-07-31 |
2023-08-11 |
rat |
| M E Dell'Anna, S Calzolari, M Molinari, L Iuvone, R Calimic. Neonatal anoxia induces transitory hyperactivity, permanent spatial memory deficits and CA1 cell density reduction in developing rats. Behavioural brain research. vol 45. issue 2. 1992-03-27. PMID:1789921. |
neonatal anoxia induces transitory hyperactivity, permanent spatial memory deficits and ca1 cell density reduction in developing rats. |
1992-03-27 |
2023-08-11 |
rat |
| A Ylinen, H Lahtinen, J Sirviö, J Partanen, A Asikainen, A Gulyas, T F Freund, P Riekkine. Behavioural, electrophysiological and histopathological changes following sustained stimulation of the perforant pathway input to the hippocampus: effect of the NMDA receptor antagonist, CGP 39551. Brain research. vol 553. issue 2. 1991-12-13. PMID:1681982. |
sustained stimulation of the perforant path has been shown to damage the ca1 area and impair spatial memory in rats. |
1991-12-13 |
2023-08-11 |
human |
| B G Lyeth, L W Jenkins, R J Hamm, C E Dixon, L L Phillips, G L Clifton, H F Young, R L Haye. Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat. Brain research. vol 526. issue 2. 1991-01-31. PMID:2257484. |
for example, following cerebral ischemia even partial hippocampal ca1 neuronal loss has been proposed to be sufficient to result in deficits in hippocampal dependent spatial memory. |
1991-01-31 |
2023-08-11 |
rat |
| B G Lyeth, L W Jenkins, R J Hamm, C E Dixon, L L Phillips, G L Clifton, H F Young, R L Haye. Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat. Brain research. vol 526. issue 2. 1991-01-31. PMID:2257484. |
this study examined if hippocampal ca1 neuronal loss and/or axonal injury was necessary to produce prolonged spatial memory deficits resulting from traumatic brain injury (tbi). |
1991-01-31 |
2023-08-11 |
rat |