| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Margaret R Starostik, Michelle R Rebello, Kellie A Cotter, Akos Kulik, Kathryn F Medle. Expression of GABAergic receptors in mouse taste receptor cells. PloS one. vol 5. issue 10. 2011-03-07. PMID:21049022. |
since the synthetic enzyme glutamate decarboxylase (gad) for gamma-aminobutyric acid (gaba) is expressed in a subset of mouse taste cells, we hypothesized that other components of the gaba signaling pathway are likely expressed in this system. |
2011-03-07 |
2023-08-12 |
mouse |
| Y A Blednov, C M Borghese, M L McCracken, J M Benavidez, C R Geil, E Osterndorff-Kahanek, D F Werner, S Iyer, A Swihart, N L Harrison, G E Homanics, R A Harri. Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors. The Journal of pharmacology and experimental therapeutics. vol 336. issue 1. 2011-01-18. PMID:20876231. |
loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing gaba(a) receptors. |
2011-01-18 |
2023-08-12 |
mouse |
| Laurent Prezeau, Marie-Laure Rives, Laëtitia Comps-Agrar, Damien Maurel, Julie Kniazeff, Jean-Philippe Pi. Functional crosstalk between GPCRs: with or without oligomerization. Current opinion in pharmacology. vol 10. issue 1. 2010-04-15. PMID:19962942. |
the class c gpcrs are well-known dimeric receptors, either homodimeric (mglu or casr) or heterodimeric (gaba(b) or taste t1r1/t1r3 and t1r2/t1r3) receptors. |
2010-04-15 |
2023-08-12 |
Not clear |
| Tadashi Inui, Takashi Yamamoto, Tsuyoshi Shimur. GABAergic transmission in the rat ventral pallidum mediates a saccharin palatability shift in conditioned taste aversion. The European journal of neuroscience. vol 30. issue 1. 2009-09-14. PMID:19523097. |
we previously found that the blockade of gamma-aminobutyric acid (gaba)(a) receptors in the ventral pallidum (vp) alters the taste palatability of a conditioned stimulus (cs) from aversive to ingestive after the establishment of conditioned taste aversion (cta). |
2009-09-14 |
2023-08-12 |
rat |
| Tadashi Inui, Takashi Yamamoto, Tsuyoshi Shimur. GABAergic transmission in the rat ventral pallidum mediates a saccharin palatability shift in conditioned taste aversion. The European journal of neuroscience. vol 30. issue 1. 2009-09-14. PMID:19523097. |
because these results suggest that gabaergic transmission in the vp mediates decreased palatability of the taste in cta, the present study aimed to examine the effects of taste stimulation on the extracellular release of gaba in the vp using in vivo microdialysis. |
2009-09-14 |
2023-08-12 |
rat |
| Anthony Disorbo, Gina N Wilson, Stephanie Bacik, Zana Hoxha, Jaclyn M Biada, G Andrew Mickle. Time-dependent retrograde amnesic effects of muscimol on conditioned taste aversion extinction. Pharmacology, biochemistry, and behavior. vol 92. issue 2. 2009-04-27. PMID:19171164. |
we explored how stimulation of gaba(a) receptors at different times during conditioned taste aversion (cta) acquisition or extinction influenced extinction. |
2009-04-27 |
2023-08-12 |
rat |
| Yu Cao, Fang-li Zhao, Tamara Kolli, Randy Hivley, Scott Hernes. GABA expression in the mammalian taste bud functions as a route of inhibitory cell-to-cell communication. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 10. 2009-03-26. PMID:19223578. |
by using immunocytochemistry, subsets of trcs within rat taste buds were identified as expressing gaba, and its synthetic enzyme glutamate decarboxylase (gad). |
2009-03-26 |
2023-08-12 |
rat |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Begoña Villar-Cheda, Ramón Anadón, María Celina Rodici. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18831528. |
we used immunofluorescence methods with antibodies raised against serotonin, tyrosine hydroxylase (th), gamma-aminobutyric acid (gaba), glutamate, calcitonin gene-related peptide (cgrp), neuropeptide y (npy), calretinin, and acetylated alpha-tubulin to characterize the neurochemistry and innervation of taste buds in the sea lamprey, petromyzon marinus l. for localization of proliferative cells in taste buds we used bromodeoxyuridine labeling and proliferating cell nuclear antigen immunohistochemistry. |
2008-12-30 |
2023-08-12 |
Not clear |
| Antón Barreiro-Iglesias, Verona Villar-Cerviño, Begoña Villar-Cheda, Ramón Anadón, María Celina Rodici. Neurochemical characterization of sea lamprey taste buds and afferent gustatory fibers: presence of serotonin, calretinin, and CGRP immunoreactivity in taste bud bi-ciliated cells of the earliest vertebrates. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18831528. |
lamprey taste bud cells or afferent fibers did not exhibit th, gaba, glutamate, or npy immunoreactivity, which suggests that expression of these substances evolved in taste buds of some gnathostomes lines after the separation of gnathostomes and lampreys. |
2008-12-30 |
2023-08-12 |
Not clear |
| Shalini Saggu, Robert F Lund. Forebrain neurons that project to the gustatory parabrachial nucleus in rat lack glutamic acid decarboxylase. American journal of physiology. Regulatory, integrative and comparative physiology. vol 294. issue 1. 2008-02-26. PMID:17989138. |
previous studies show that activation of the gustatory cortex (gc), bed nucleus of the stria terminalis (bnst), central nucleus of the amygdala (cea), and lateral hypothalamus (lh) inhibits pbn taste responses, gabaergic neurons are present in these forebrain regions, and gaba reduces the input resistance of pbn neurons. |
2008-02-26 |
2023-08-12 |
rat |
| Rosaria Remelli, Melanie J Robbins, R A Jeffrey McIlhinne. The C-terminus of the metabotropic glutamate receptor 1b regulates dimerization of the receptor. Journal of neurochemistry. vol 104. issue 4. 2008-02-14. PMID:17995933. |
the group c g protein-coupled receptors include the metabotropic glutamate receptors (mglurs), the gaba(b) receptor, the calcium sensor and several taste receptors, most of which are obligate dimers, indeed recent work has shown that dimerization is necessary for the activation of these receptors. |
2008-02-14 |
2023-08-12 |
Not clear |
| Hans Bräuner-Osborne, Petrine Wellendorph, Anders A Jense. Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors. Current drug targets. vol 8. issue 1. 2007-03-30. PMID:17266540. |
family c of g-protein coupled receptors (gpcrs) from humans is constituted by eight metabotropic glutamate (mglu(1-8)) receptors, two heterodimeric gamma-aminobutyric acid(b) (gaba(b)) receptors, a calcium-sensing receptor (car), three taste (t1r) receptors, a promiscuous l-alpha-amino acid receptor (gprc6a), and five orphan receptors. |
2007-03-30 |
2023-08-12 |
Not clear |
| Laura H Jacobson, Peter H Kelly, Bernhard Bettler, Klemens Kaupmann, John F Crya. GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928868. |
gaba(b(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories. |
2006-09-28 |
2023-08-12 |
mouse |
| Timo Stark, Sabine Bareuther, Thomas Hofman. Molecular definition of the taste of roasted cocoa nibs (Theobroma cacao) by means of quantitative studies and sensory experiments. Journal of agricultural and food chemistry. vol 54. issue 15. 2006-08-29. PMID:16848542. |
to further narrow down the number of key taste compounds, finally, taste omission experiments and human dose/response functions were performed, demonstrating that the bitter-tasting alkaloids theobromine and caffeine, seven bitter-tasting diketopiperazines, seven bitter- and astringent-tasting flavan-3-ols, six puckering astringent n-phenylpropenoyl-l-amino acids, four velvety astringent flavonol glycosides, gamma-aminobutyric acid, beta-aminoisobutyric acid, and six organic acids are the key organoleptics of the roasted cocoa nibs. |
2006-08-29 |
2023-08-12 |
human |
| Tsuyoshi Shimura, Hiroyuki Imaoka, Takashi Yamamot. Neurochemical modulation of ingestive behavior in the ventral pallidum. The European journal of neuroscience. vol 23. issue 6. 2006-05-30. PMID:16553623. |
these results reveal that gaba, opioid and d1 receptors in the vp are involved in the consumption of hedonically positive taste stimuli. |
2006-05-30 |
2023-08-12 |
rat |
| Minghua Wang, David R Hampso. An evaluation of automated in silico ligand docking of amino acid ligands to Family C G-protein coupled receptors. Bioorganic & medicinal chemistry. vol 14. issue 6. 2006-05-25. PMID:16297630. |
family c g-protein coupled receptors (gpcrs) consist of the metabotropic glutamate receptors (mglurs), the calcium-sensing receptor (casr), the t1r taste receptors, the gaba(b) receptor, the v2r pheromone receptors, and several chemosensory receptors. |
2006-05-25 |
2023-08-12 |
Not clear |
| M Eram, W C Miche. Heterogeneous distribution of taste cells in facial and vagal nerve-innervated taste buds. Neuroscience. vol 138. issue 1. 2006-05-24. PMID:16387446. |
the distributions of five low molecular weight metabolites, l-alanine, l-aspartate, l-glutamate, gaba, taurine and the tripeptide glutathione, were examined in 2118 individual taste cells innervated by either the facial or vagal nerve of the channel catfish, ictalurus punctatus. |
2006-05-24 |
2023-08-12 |
Not clear |
| Minghua Wang, Yi Yao, Donghui Kuang, David R Hampso. Activation of family C G-protein-coupled receptors by the tripeptide glutathione. The Journal of biological chemistry. vol 281. issue 13. 2006-05-23. PMID:16455645. |
the family c g-protein-coupled receptors include the metabotropic glutamate receptors, the gamma-aminobutyric acid, type b (gabab) receptor, the calcium-sensing receptor (casr), which participates in the regulation of calcium homeostasis in the body, and a diverse group of sensory receptors that encompass the amino acid-activated fish 5.24 chemosensory receptor, the mammalian t1r taste receptors, and the v2r pheromone receptors. |
2006-05-23 |
2023-08-12 |
rat |
| Nina Rotzoll, Andreas Dunkel, Thomas Hofman. Quantitative studies, taste reconstitution, and omission experiments on the key taste compounds in morel mushrooms (Morchella deliciosa Fr.). Journal of agricultural and food chemistry. vol 54. issue 7. 2006-04-28. PMID:16569064. |
to finally narrow down the number of key taste compounds, taste omission experiments were performed demonstrating that (s)-morelid together with l-glutamic acid, l-aspartic acid, malic acid, citric acid, acetic acid, and gamma-aminobutyric acid are the key organoleptics of morel extract. |
2006-04-28 |
2023-08-12 |
human |
| Jennifer Ong, David I B Ker. Clinical potential of GABAB receptor modulators. CNS drug reviews. vol 11. issue 3. 2006-02-08. PMID:16389296. |
metabotropic gamma-aminobutyric acid(b) (gabab) receptors for the major inhibitory transmitter gaba, together with metabotropic glutamate (mglurs) receptors, the extracellular calcium-sensing receptors (casrs), some v2r pheromone receptors and t1r taste receptors, belong to the family of 3 g-protein-coupled receptors (gpcrs). |
2006-02-08 |
2023-08-12 |
Not clear |