| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lyl Tomlinson, Po Hsuan Huang, Holly Colognat. Prefrontal cortex NG2 glia undergo a developmental switch in their responsiveness to exercise. Developmental neurobiology. vol 78. issue 7. 2018-11-08. PMID:29569358. |
yet oligodendroglia in adult brains have also been reported to be highly responsive to exercise, including in the prefrontal cortex (pfc), a late myelinating region implicated in working memory. |
2018-11-08 |
2023-08-13 |
mouse |
| Linling Jiang, Yuqi Cheng, Hongyan Jiang, Jian Xu, Jin Lu, Zonglin Shen, Yi Lu, Fang Liu, Luqiong Li, Xiufeng X. Association between abnormal serum myelin-specific protein levels and white matter integrity in first-episode and drug-naïve patients with major depressive disorder. Journal of affective disorders. vol 232. 2018-08-31. PMID:29477585. |
the current study aimed to investigate the myelin oligodendrocyte glycoprotein (mog) and myelin-associated glycoprotein (mag) levels and their correlations with wm integrity in first-episode, drug-naïve mdd patients. |
2018-08-31 |
2023-08-13 |
Not clear |
| Emine B Yalcin, Tory McLean, Ming Tong, Suzanne M de la Mont. Progressive white matter atrophy with altered lipid profiles is partially reversed by short-term abstinence in an experimental model of alcohol-related neurodegeneration. Alcohol (Fayetteville, N.Y.). vol 65. 2018-06-19. PMID:29084630. |
since myelin is composed of oligodendrocyte lipid-rich membranes, understanding the consequences and reversibility of alcohol-related oligodendrocyte dysfunction in relation to myelin structure could provide new insights into the pathogenesis of wm degeneration and potential strategies for treatment. |
2018-06-19 |
2023-08-13 |
rat |
| Ting Zhou, Tina Khorshid Ahmad, Kiana Gozda, Jessica Truong, Jiming Kong, Michael Namak. Implications of white matter damage in amyotrophic lateral sclerosis (Review). Molecular medicine reports. vol 16. issue 4. 2018-05-14. PMID:28791401. |
als has long been considered a disease of the grey matter; however, pathological alterations of the white matter (wm), including axonal loss, axonal demyelination and oligodendrocyte death, have been reported in patients with als. |
2018-05-14 |
2023-08-13 |
Not clear |
| Jessie Newville, Carlos Fernando Valenzuela, Lu Li, Lauren L Jantzie, Lee Anna Cunningha. Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder. Glia. vol 65. issue 8. 2018-02-02. PMID:28518477. |
here, we evaluated both the acute and long-term impacts of alcohol exposure on oligodendrocyte number and wm integrity in a third trimester-equivalent mouse model of fasd, in which mouse pups were exposed to alcohol during the first 2 weeks of postnatal development. |
2018-02-02 |
2023-08-13 |
mouse |
| Eva M M Strijbis, Evert-Jan Kooi, Paul van der Valk, Jeroen J G Geurt. Cortical Remyelination Is Heterogeneous in Multiple Sclerosis. Journal of neuropathology and experimental neurology. vol 76. issue 5. 2017-08-07. PMID:28521040. |
because remyelination can be extensive in cls, we quantified remyelination in gray matter (gm) and white matter (wm), addressing oligodendrocyte (ogd) maturation state and clinical relevance of remyelination. |
2017-08-07 |
2023-08-13 |
Not clear |
| Anne Joutel, Hugues Chabria. Pathogenesis of white matter changes in cerebral small vessel diseases: beyond vessel-intrinsic mechanisms. Clinical science (London, England : 1979). vol 131. issue 8. 2017-07-03. PMID:28351960. |
specifically, building on two recent seminal studies that have uncovered an anatomical and functional relationship between oligodendrocyte progenitor cells and blood vessels, we elaborate on how small vessel changes might compromise myelin remodelling and cause wm degeneration. |
2017-07-03 |
2023-08-13 |
Not clear |
| Li-Jin Chew, Cynthia A DeBo. Pharmacological approaches to intervention in hypomyelinating and demyelinating white matter pathology. Neuropharmacology. vol 110. issue Pt B. 2017-05-23. PMID:26116759. |
here we highlight reports of studies in the cns in which compounds, namely peptides, hormones, and small molecule agonists/antagonists, have been used in experimental animal models of demyelination and neonatal brain injury that affect aspects of excitotoxicity, oligodendrocyte development and survival, and progenitor cell function, and which have been demonstrated to attenuate damage and improve wm protection in experimental models of injury. |
2017-05-23 |
2023-08-13 |
Not clear |
| Li-Jin Chew, Cynthia A DeBo. Pharmacological approaches to intervention in hypomyelinating and demyelinating white matter pathology. Neuropharmacology. vol 110. issue Pt B. 2017-05-23. PMID:26116759. |
by surveying the current evidence in non-immune targets of both the immature and mature wm, we aim to better understand pharmacological approaches modulating endogenous oligodendroglia that show potential for success in the contexts of developmental and adult wm pathology. |
2017-05-23 |
2023-08-13 |
Not clear |
| Ivan Chavarria-Siles, Tonya White, Christiaan de Leeuw, Andrea Goudriaan, Esther Lips, Stefan Ehrlich, Jessica A Turner, Vince D Calhoun, Randy L Gollub, Vincent A Magnotta, Beng-Choon Ho, August B Smit, Mark H G Verheijen, Danielle Posthum. Myelination-related genes are associated with decreased white matter integrity in schizophrenia. European journal of human genetics : EJHG. vol 24. issue 3. 2016-10-31. PMID:26014434. |
we analyzed fa and genetic data from the mind research network clinical imaging consortium to study the effect of multiple oligodendrocyte gene sets on schizophrenia and wm integrity using a functional gene set analysis in 77 subjects with schizophrenia and 104 healthy controls. |
2016-10-31 |
2023-08-13 |
human |
| Marcella Bellani, Filippo Boschello, Giuseppe Delvecchio, Nicola Dusi, Carlo Alfredo Altamura, Mirella Ruggeri, Paolo Brambill. DTI and Myelin Plasticity in Bipolar Disorder: Integrating Neuroimaging and Neuropathological Findings. Frontiers in psychiatry. vol 7. 2016-03-14. PMID:26973545. |
in this report, we summarize and comment recent findings from dti studies in bd, reporting fractional anisotropy as putative measure of wm integrity, as well as recent data from neuropathological studies focusing on oligodendrocyte involvement in wm alterations in bd. |
2016-03-14 |
2023-08-13 |
Not clear |
| W-J Li, F-X Mao, H-J Chen, L-H Qian, J S Buzb. Treatment with UDP-glucose, GDNF, and memantine promotes SVZ and white matter self-repair by endogenous glial progenitor cells in neonatal rats with ischemic PVL. Neuroscience. vol 284. 2015-12-22. PMID:25453769. |
labeling with 5'-bromo-2'-deoxyuridine and immunofluorescent cell lineage markers after hypoxia-ischemia or oxygen-glucose deprivation (ogd) revealed that udpg, gdnf and memantine each significantly increased glial progenitor cells and preoligodendrocytes (preols), as well as more differentiated immature and mature oligodendrocyte (ol), in both the svz and wm in vivo or in vitro. |
2015-12-22 |
2023-08-13 |
rat |
| Izumi Kawachi, Etsuji Saji, Masatoyo Nishizaw. [Gray matter lesions and cognitive impairment in multiple sclerosis]. Rinsho shinkeigaku = Clinical neurology. vol 54. issue 12. 2015-10-19. PMID:25672709. |
multiple sclerosis (ms) has long been considered to be the autoimmune disease that primarily affects oligodendrocyte and myelin in the white matter (wm) of the cns. |
2015-10-19 |
2023-08-13 |
Not clear |
| Robert F Fern, Carlos Matute, Peter K Sty. White matter injury: Ischemic and nonischemic. Glia. vol 62. issue 11. 2015-05-15. PMID:25043122. |
axons may pass through four developmental stages where the pattern of membrane protein expression influences how the structure responds to ischemia; wm astrocytes pass through at least two and differ significantly in their ischemia tolerance from grey matter astrocytes; oligodendroglia pass through at least three, with the highly ischemia intolerant pre-oligodendrocyte (pre-oli) stage linking the less sensitive precursor and mature phenotypes. |
2015-05-15 |
2023-08-13 |
Not clear |
| Sinead Kelly, Derek W Morris, Omar Mothersill, Emma Jane Rose, Ciara Fahey, Carol O'Brien, Erik O'Hanlon, Michael Gill, Aiden P Corvin, Gary Donoho. Genome-wide schizophrenia variant at MIR137 does not impact white matter microstructure in healthy participants. Neuroscience letters. vol 574. 2014-12-18. PMID:24820543. |
as mirnas have the potential to influence oligodendrocyte development, we investigated whether this snp was associated with variability in white matter (wm) microstructure. |
2014-12-18 |
2023-08-13 |
human |
| Tou Yia Vue, Euiseok J Kim, Carlos M Parras, Francois Guillemot, Jane E Johnso. Ascl1 controls the number and distribution of astrocytes and oligodendrocytes in the gray matter and white matter of the spinal cord. Development (Cambridge, England). vol 141. issue 19. 2014-11-24. PMID:25249462. |
conditional deletion of ascl1 post-neurogenesis shows that ascl1 is required during oligodendrogenesis for generating the correct numbers of wm but not gm oligodendrocyte precursor cells, whereas during astrocytogenesis ascl1 functions in balancing the number of dorsal gm protoplasmic astrocytes with dorsal wm fibrous astrocytes. |
2014-11-24 |
2023-08-13 |
mouse |
| Xiaotian Ming, Li-Jin Chew, Vittorio Gall. Transgenic overexpression of Sox17 promotes oligodendrocyte development and attenuates demyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 30. 2013-10-17. PMID:23884956. |
here we investigated its function in white matter (wm) development and adult injury with a newly generated transgenic mouse overexpressing sox17 in the oligodendrocyte lineage under the cnpase promoter. |
2013-10-17 |
2023-08-12 |
mouse |
| Xiaotian Ming, Li-Jin Chew, Vittorio Gall. Transgenic overexpression of Sox17 promotes oligodendrocyte development and attenuates demyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 30. 2013-10-17. PMID:23884956. |
cnp-sox17 mice showed increased gli2 protein levels and gli2+ cells in wm, indicating that sox17 promotes the generation of oligodendrocyte lineage cells through hedgehog signaling. |
2013-10-17 |
2023-08-12 |
mouse |
| Xiaotian Ming, Li-Jin Chew, Vittorio Gall. Transgenic overexpression of Sox17 promotes oligodendrocyte development and attenuates demyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 30. 2013-10-17. PMID:23884956. |
our study thus reveals a biphasic effect of sox17 overexpression on cell survival and oligodendrocyte formation in the developing wm, and that its potentiation of oligodendrocyte survival in the adult confers resistance to injury and myelin loss. |
2013-10-17 |
2023-08-12 |
mouse |
| Steven G Kohama, Douglas L Rosene, Larry S Sherma. Age-related changes in human and non-human primate white matter: from myelination disturbances to cognitive decline. Age (Dordrecht, Netherlands). vol 34. issue 5. 2013-03-12. PMID:22203458. |
here, we review both cross-sectional and longitudinal studies in humans and non-human primates that collectively support the hypothesis that wm disturbances increase with age starting at middle age in humans, that these disturbances contribute to age-related cognitive decline, and that age-related wm changes may occur as a result of free radical damage, degenerative changes in cells in the oligodendrocyte lineage, and changes in microenvironments within wm. |
2013-03-12 |
2023-08-12 |
human |