All Relations between 5-ht receptor 1a and 5-ht receptor 2a

Publication Sentence Publish Date Extraction Date Species
D W Bonhaus, D N Loury, L B Jakeman, Z To, A DeSouza, R M Eglen, E H Won. [3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus. The Journal of pharmacology and experimental therapeutics. vol 267. issue 2. 1994-01-06. PMID:8246171. the affinity of bimu-1 for sigma-2 binding sites (ki = 32 nm) was 200-fold greater than that for sigma-1 binding sites (ki = 6.3 microm), dopamine (d1 and d2), other serotonin (5-ht1a, 5-ht2a, 5-ht2c) and muscarinic (m1, m2, m3 and m4) receptors (ki > 10 microm). 1994-01-06 2023-08-12 Not clear
C M Brown, A T Kilpatrick, A Martin, M Speddin. Cerebral ischaemia reduces the density of 5-HT2 binding sites in the frontal cortex of the gerbil. Neuropharmacology. vol 27. issue 8. 1989-03-03. PMID:3216962. specific binding of [3h]ketanserin was displaced by a number of 5-ht2a antagonists ritanserin, cyproheptadine and methysergide) but not by the 5-ht1a agonist, 8-hydroxy-2-(di-n- propylamino)tetralin (8-oh-dpat) or the 5-ht1a/1b agonists 5-carboxyamidotryptamine (5-ct) or ru 24969, indicating that the labelled site probably represents the 5-ht2 receptor. 1989-03-03 2023-08-11 Not clear