| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Apeksha Parajulee, Kuglae Ki. Structural studies of serotonin receptor family. BMB reports. 2023-10-11. PMID:37817438. |
the functions of serotonin are mediated by a family of 5-ht receptors including 12 gpcrs belonging to six major families: 5-ht1, 5-ht2, 5-ht4, 5-ht5, 5-ht6 and 5-ht7. |
2023-10-11 |
2023-10-15 |
Not clear |
| Xiaolong Gao, Mo Zhang, Shihui Lin, Mingxin Lyu, Xuan Luo, Weiwei You, Caihuan K. Reproduction strategy of nocturnal marine molluscs: running for love. Integrative zoology. 2023-01-07. PMID:36609825. |
after 24 h uninterrupted sampling, the concentration of 5-ht and the expression levels of the 5-ht2 and 5-ht6 receptors in am were significantly higher than those in jm. |
2023-01-07 |
2023-08-14 |
Not clear |
| Xiaolong Gao, Mo Zhang, Shihui Lin, Mingxin Lyu, Xuan Luo, Weiwei You, Caihuan K. Reproduction strategy of nocturnal marine molluscs: running for love. Integrative zoology. 2023-01-07. PMID:36609825. |
after further injection of 5-ht2 and 5-ht6 receptor antagonists, the concentrations of camp and pka rose again, but the cumulative movement duration and distance of male abalones decreased significantly, showing that 5-ht was involved in the regulation of movement behavior of male abalones through the 5-ht2 and 5-ht6 receptor-activated camp-pka pathways. |
2023-01-07 |
2023-08-14 |
Not clear |
| Kyeong Seop Kim, Mi Ae Kim, Young Chang Soh. Molecular characterization, expression analysis, and functional properties of multiple 5-hydroxytryptamine receptors in Pacific abalone (Haliotis discus hannai). General and comparative endocrinology. vol 276. 2019-05-17. PMID:30849410. |
a phylogenetic analysis indicated that the molluskan 5-ht receptors are largely classified into four major clades: 5-ht1/5/7, 5-ht2, 5-ht4, and 5-ht6. |
2019-05-17 |
2023-08-13 |
Not clear |
| D J David, A M Gardie. [The pharmacological basis of the serotonin system: Application to antidepressant response]. L'Encephale. vol 42. issue 3. 2017-09-20. PMID:27112704. |
physiological effects of 5-ht are mediated by about 15 serotoninergic receptors grouped into seven broad families (5-ht1, 5-ht2, 5-ht3, 5-ht4, 5-ht5, 5-ht6, 5-ht7 receptor families). |
2017-09-20 |
2023-08-13 |
Not clear |
| Yukihiro Ohno, Saki Shimizu, Kentaro Tokudome, Naofumi Kunisawa, Masashi Sas. New insight into the therapeutic role of the serotonergic system in Parkinson's disease. Progress in neurobiology. vol 134. 2016-08-25. PMID:26455457. |
among 5-ht receptor subtypes, 5-ht1a, 5-ht2, 5-ht3 and 5-ht6 receptors play an important role in modulating extrapyramidal motor disorders. |
2016-08-25 |
2023-08-13 |
Not clear |
| Yukihiro Ohno, Saki Shimizu, Kentaro Tokudome, Naofumi Kunisawa, Masashi Sas. New insight into the therapeutic role of the serotonergic system in Parkinson's disease. Progress in neurobiology. vol 134. 2016-08-25. PMID:26455457. |
in addition, 5-ht1a, 5-ht2, 5-ht3, 5-ht4 and 5-ht6 receptors are implicated in modulation of cognitive impairment, mood disorders (e.g., depression and anxiety) and/or psychosis, which are frequently observed in patients with pd. |
2016-08-25 |
2023-08-13 |
Not clear |
| Saki Shimizu, Yuto Mizuguchi, Akira Sobue, Mai Fujiwara, Tomoki Morimoto, Yukihiro Ohn. Interaction between anti-Alzheimer and antipsychotic drugs in modulating extrapyramidal motor disorders in mice. Journal of pharmacological sciences. vol 127. issue 4. 2016-03-14. PMID:25850380. |
in addition, the bradykinesia potentiation by galantamine was significantly reduced by (±)-8-hydroxy-2-(di-n-propylamino)-tetralin (a 5-ht1a agonist), ritanserin (a 5-ht2 antagonist), and sb-258585 (a 5-ht6 antagonist). |
2016-03-14 |
2023-08-13 |
mouse |
| Yunpeng Du, Megan Cramer, Chieh Allen Lee, Jie Tang, Arivalagan Muthusamy, David A Antonetti, Hui Jin, Krzysztof Palczewski, Timothy S Ker. Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 29. issue 5. 2015-07-30. PMID:25667222. |
this response was reduced or ablated by pharmacologic inhibition of the α1-ar (a gq-coupled receptor) or gs-coupled serotonin (5-ht2, 5-ht4, 5-ht6, and 5-ht7) receptors or by activation of the gi-coupled α2-ar. |
2015-07-30 |
2023-08-13 |
mouse |
| W J Xu, Y Zhao, F Q Huo, J Q Du, J S Tan. Involvement of ventrolateral orbital cortex 5-HT 1-7 receptors in 5-HT induced depression of spared nerve injury allodynia. Neuroscience. vol 238. 2013-10-17. PMID:23485814. |
the present study examined the roles of ventrolateral orbital cortex (vlo) 5-ht1, 5-ht2, 5-ht3, 5-ht4, 5-ht5, 5-ht6 and 5-ht7 receptor subtypes in mediating 5-ht-induced antiallodynic actions in the rat spared nerve injury (sni) pain model. |
2013-10-17 |
2023-08-12 |
rat |
| W J Xu, Y Zhao, F Q Huo, J Q Du, J S Tan. Involvement of ventrolateral orbital cortex 5-HT 1-7 receptors in 5-HT induced depression of spared nerve injury allodynia. Neuroscience. vol 238. 2013-10-17. PMID:23485814. |
microinjection of selective 5-ht1a, 5-ht2, 5-ht3, 5-ht4, 5-ht5a, 5-ht6 and 5-ht7 receptor antagonists, 1-(2-methoxyphenyl)-4-[4-(2-phthalimido)butyl] piperazine hydrobromide (nan-190) (10μg), cyproheptadine (50ng), granisetron hydrochloride (granisetron) (10μg), 1-[2-[(methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl1-methyl-1h-indole-3-carboxylate (gr113808) (5μg), sb699551 dihydrochloride (sb699551) (10μg), sb258585 dihydrochloride (sb258585) (2μg) or sb269970 hydrochloride (sb269970) (10μg) into the vlo 5-min prior to 5-ht (10μg) injection, all antagonized the 5-ht-induced inhibition of allodynia. |
2013-10-17 |
2023-08-12 |
rat |
| John C Talpos, Lawrence S Wilkinson, Trevor W Robbin. A comparison of multiple 5-HT receptors in two tasks measuring impulsivity. Journal of psychopharmacology (Oxford, England). vol 20. issue 1. 2006-03-29. PMID:16204332. |
to test this hypothesis, behavioural effects of three partially selective serotonergic (5-ht) ligands, ketanserin (5-ht2(a, c) receptor antagonist), ser-082 (5-ht2(c, b) receptor antagonist) and sb-270146-a (5-ht6 receptor antagonist) were compared in two tests of impulsivity. |
2006-03-29 |
2023-08-12 |
Not clear |
| Michelle McGuire, Yi Zhang, David P White, Liming Lin. Serotonin receptor subtypes required for ventilatory long-term facilitation and its enhancement after chronic intermittent hypoxia in awake rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 286. issue 2. 2004-02-27. PMID:14551171. |
collectively, these data suggest that ventilatory ltf requires 5-ht2 receptors and that the cih effect on ltf requires non-5-ht2 serotonin receptors, probably 5-ht6 and/or 5-ht7 subtype(s). |
2004-02-27 |
2023-08-12 |
rat |
| N H Prins, L M Akkermans, R A Lefebvre, J A Schuurke. Characterization of the receptors involved in the 5-HT-induced excitation of canine antral longitudinal muscle. British journal of pharmacology. vol 134. issue 6. 2002-03-15. PMID:11704657. |
there were non-significant trends of the selective 5-ht3 receptor antagonist granisetron (1 microm), and methysergide (1 microm; preventing interactions of 5-ht with 5-ht1, 5-ht2, 5-ht5, 5-ht6 and 5-ht7 receptors) to increase the response to 5-ht. |
2002-03-15 |
2023-08-12 |
dog |
| F Bymaster, K W Perry, D L Nelson, D T Wong, K Rasmussen, N A Moore, D O Calligar. Olanzapine: a basic science update. The British journal of psychiatry. Supplement. issue 37. 1999-05-10. PMID:10211140. |
in vitro receptor binding studies showed a high affinity for dopamine d2, d3, and d4 receptors; all 5-ht2 receptor subtypes and the 5-ht6 receptor; muscarinic receptors, especially the m1 subtype: and alpha 1-adrenergic receptors. |
1999-05-10 |
2023-08-12 |
Not clear |
| A Merzak, S Koochekpour, M P Fillion, G Fillion, G J Pilkingto. Expression of serotonin receptors in human fetal astrocytes and glioma cell lines: a possible role in glioma cell proliferation and migration. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883928. |
expression of seven serotonin or 5-hydroxytryptamine (5-ht) receptors (5-ht1d alpha, 5-ht1e, 5-ht2, 5-ht1a, 5-ht1c, 5-ht1d beta, and 5-ht6) was investigated in human normal fetal astrocytes and eight glioma cell lines by reverse transcription and polymerase chain reaction (rt-pcr). |
1997-02-20 |
2023-08-12 |
human |
| R B Raffa, E E Cod. Lack of binding of acetaminophen to 5-HT receptor or uptake sites (or eleven other binding/uptake assays). Life sciences. vol 59. issue 2. 1996-08-30. PMID:8699917. |
in the present study, we measured the affinity of acetaminophen at 5-ht3, as well as 5-ht1a, 5-ht1b, 5-ht1d, 5-ht2, 5-ht2c, 5-ht4, 5-ht6, 5-ht7 and eleven other receptor sites and at serotonin and norepinephrine reuptake sites. |
1996-08-30 |
2023-08-12 |
Not clear |
| S C Pandey, J M Davis, G N Pande. Phosphoinositide system-linked serotonin receptor subtypes and their pharmacological properties and clinical correlates. Journal of psychiatry & neuroscience : JPN. vol 20. issue 3. 1995-07-27. PMID:7786883. |
serotonin (5-ht) receptors have been classified into several categories, and they are termed as 5-ht1, 5-ht2, 5-ht3, 5-ht4, 5-ht5, 5-ht6 and 5-ht7 type receptors. |
1995-07-27 |
2023-08-12 |
Not clear |