| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Dogrul, M Seyre. Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord. British journal of pharmacology. vol 149. issue 5. 2007-02-02. PMID:16921395. |
systemic morphine produce antinociception mediated by spinal 5-ht7, but not 5-ht1a and 5-ht2 receptors in the spinal cord. |
2007-02-02 |
2023-08-12 |
Not clear |
| Luciane H Gargaglioni, Kênia C Bícego, Tatiane B Nucci, Luiz G S Branc. Serotoninergic receptors in the anteroventral preoptic region modulate the hypoxic ventilatory response. Respiratory physiology & neurobiology. vol 153. issue 1. 2006-09-29. PMID:16310416. |
once 5-ht is involved in the hypoxic ventilatory response (hvr), we investigated the participation of the 5-ht receptors (5-ht1, 5-ht2 and 5-ht7) in the avpo in the hvr. |
2006-09-29 |
2023-08-12 |
rat |
| Luciane H Gargaglioni, Kênia C Bícego, Tatiane B Nucci, Luiz G S Branc. Serotoninergic receptors in the anteroventral preoptic region modulate the hypoxic ventilatory response. Respiratory physiology & neurobiology. vol 153. issue 1. 2006-09-29. PMID:16310416. |
to this end, pulmonary ventilation (v(e)) of rats was measured before and after intra-avpo microinjection of methysergide (a 5-ht1 and 5-ht2 receptor antagonist), way-100635 (a 5-ht1a receptor antagonist) and sb-269970 (a 5-ht7 receptor antagonist), followed by 60 min of hypoxia exposure (7% o2). |
2006-09-29 |
2023-08-12 |
rat |
| Craig Blomeley, Enrico Bracc. Excitatory effects of serotonin on rat striatal cholinergic interneurones. The Journal of physiology. vol 569. issue Pt 3. 2006-05-04. PMID:16269435. |
selective agonists of 5-ht(1a), 5-ht3, 5-ht4 and 5-ht7 receptors did not affect cholinergic interneurone firing, while the 5-ht2 receptor agonist alpha-methyl-5-ht (30 microm) mimicked the excitatory effects of serotonin. |
2006-05-04 |
2023-08-12 |
rat |
| Nonna A Otmakhova, Jennifer Lewey, Brent Asrican, John E Lisma. Inhibition of perforant path input to the CA1 region by serotonin and noradrenaline. Journal of neurophysiology. vol 94. issue 2. 2005-09-22. PMID:15888529. |
of these, only the 5-ht7 and 5-ht2 antagonists produced weak but significant inhibition of 5-ht effect. |
2005-09-22 |
2023-08-12 |
Not clear |
| Nonna A Otmakhova, Jennifer Lewey, Brent Asrican, John E Lisma. Inhibition of perforant path input to the CA1 region by serotonin and noradrenaline. Journal of neurophysiology. vol 94. issue 2. 2005-09-22. PMID:15888529. |
we conclude that ne inhibits the pp fepsp through postsynaptic action on alpha2-adrenoceptors and that 5-ht7, 5-ht2, and some other receptor may be involved in 5-ht action in pp. |
2005-09-22 |
2023-08-12 |
Not clear |
| Luciane H Gargaglioni, Alexandre A Steiner, Luiz G S Branc. Involvement of serotoninergic receptors in the anteroventral preoptic region on hypoxia-induced hypothermia. Brain research. vol 1044. issue 1. 2005-07-15. PMID:15862785. |
thus, we investigated the participation of the 5-ht receptors (5-ht1, 5-ht2, and 5-ht7) in the avpo in hypoxic hypothermia. |
2005-07-15 |
2023-08-12 |
rat |
| Luciane H Gargaglioni, Alexandre A Steiner, Luiz G S Branc. Involvement of serotoninergic receptors in the anteroventral preoptic region on hypoxia-induced hypothermia. Brain research. vol 1044. issue 1. 2005-07-15. PMID:15862785. |
to this end, tb of conscious wistar rats was monitored by biotelemetry before and after intra-avpo microinjection of methysergide (a 5-ht1 and 5-ht2 receptor antagonist, 0.2 and 2 microg/100 nl), way-100635 (a 5-ht(1a) receptor antagonist, 0.3 and 3 microg/100 nl), and sb-269970 (a 5-ht7 receptor antagonist, 0.4 and 4 micro/100 nl), followed by 60 min of hypoxia exposure (7% o2). |
2005-07-15 |
2023-08-12 |
rat |
| David Jorda. Vagal control of the heart: central serotonergic (5-HT) mechanisms. Experimental physiology. vol 90. issue 2. 2005-07-05. PMID:15604109. |
we have demonstrated roles for some of the numerous 5-ht receptor subtypes (5-ht1, 5-ht2, 5-ht3, 5-ht4 and 5-ht7) in brainstem regions involved in cardiac control. |
2005-07-05 |
2023-08-12 |
Not clear |
| Geoffrey Andrew Lambert, Cathy Donaldson, Karen Lisa Hoskin, Peter Michael Boers, Alessandro Stefano Zagam. Dilatation induced by 5-HT in the middle meningeal artery of the anaesthetised cat. Naunyn-Schmiedeberg's archives of pharmacology. vol 369. issue 6. 2005-02-22. PMID:15197536. |
we conclude that intravenously-administered 5-ht is a vasodilator in vivo in the cat dural circulation, and that the dilation is not mediated by 5-ht1, 5-ht2, 5-ht4 or 5-ht7 receptors, but is primarily mediated by a vagal reflex, initiated via 5-ht3 receptor activation and brought about by an increase in parasympathetic tone to the middle meningeal artery as part of the von bezold-jarisch reflex. |
2005-02-22 |
2023-08-12 |
cat |
| Araceli Sánchez-Lopez, David Centurión, Erika Vázquez, Udayasankar Arulmani, Pramod R Saxena, Carlos M Villaló. Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors. British journal of pharmacology. vol 140. issue 4. 2004-11-09. PMID:14504136. |
treatment with saline or the antagonists gr 127935 (5-ht1b/1d), the combination of way 100635 (5-ht1a) plus gr 127935, ritanserin (5-ht2), tropisetron (5-ht3/4), ly215840 (5-ht7) or a cocktail of antagonists/inhibitors consisting of yohimbine (alpha2), prazosin (alpha1), ritanserin, gr 127935, way 100635 and indomethacin (cyclooxygenase), but was abolished by methiothepin (5-ht1/2/6/7 and recombinant 5-ht5a/5b). |
2004-11-09 |
2023-08-12 |
rat |
| Michelle McGuire, Yi Zhang, David P White, Liming Lin. Serotonin receptor subtypes required for ventilatory long-term facilitation and its enhancement after chronic intermittent hypoxia in awake rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 286. issue 2. 2004-02-27. PMID:14551171. |
collectively, these data suggest that ventilatory ltf requires 5-ht2 receptors and that the cih effect on ltf requires non-5-ht2 serotonin receptors, probably 5-ht6 and/or 5-ht7 subtype(s). |
2004-02-27 |
2023-08-12 |
rat |
| N H Prins, L M Akkermans, R A Lefebvre, J A Schuurke. Characterization of the receptors involved in the 5-HT-induced excitation of canine antral longitudinal muscle. British journal of pharmacology. vol 134. issue 6. 2002-03-15. PMID:11704657. |
there were non-significant trends of the selective 5-ht3 receptor antagonist granisetron (1 microm), and methysergide (1 microm; preventing interactions of 5-ht with 5-ht1, 5-ht2, 5-ht5, 5-ht6 and 5-ht7 receptors) to increase the response to 5-ht. |
2002-03-15 |
2023-08-12 |
dog |
| E M Chapin, R Andrad. A 5-HT(7) receptor-mediated depolarization in the anterodorsal thalamus. I. Pharmacological characterization. The Journal of pharmacology and experimental therapeutics. vol 297. issue 1. 2001-05-03. PMID:11259568. |
we found that the 5-ht1 and 5-ht7 agonists 5-carboxamidotryptamine (5-ct) and 5-methoxytryptamine mimicked the response to 5-ht, whereas the 5-ht2 agonist 2,5-dimethoxy-4-iodoamphetamine did not. |
2001-05-03 |
2023-08-12 |
Not clear |
| R Ranganathan, S C Cannon, H R Horvit. MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans. Nature. vol 408. issue 6811. 2000-12-28. PMID:11100728. |
the neurotransmitter and neuromodulator serotonin (5-ht) functions by binding either to metabotropic g-protein-coupled receptors (for example, 5-ht1, 5-ht2, 5-ht4 to 5-ht7), which mediate 'slow' modulatory responses through numerous second messenger pathways, or to the ionotropic 5-ht3 receptor, a non-selective cation channel that mediates 'fast' membrane depolarizations. |
2000-12-28 |
2023-08-12 |
caenorhabditis_elegans |
| M P Arolfo, B A McMille. Effects of amperozide and tiospirone, atypical antipsychotic 5-HT2 drugs, on food-reinforced behavior in rats. Physiology & behavior. vol 68. issue 1-2. 2000-01-31. PMID:10627067. |
tiospirone (tsp) is a 5-ht2 receptor antagonist with affinity for d2, 5-ht1a, and 5-ht7, and sigma receptors, which can decrease consumption of ethanol while increasing food intake. |
2000-01-31 |
2023-08-12 |
rat |
| N H Prins, J F Van Haselen, R A Lefebvre, M R Briejer, L M Akkermans, J A Schuurke. Pharmacological characterization of 5-HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle. British journal of pharmacology. vol 127. issue 6. 1999-10-18. PMID:10455293. |
the presence of methysergide rules out the involvement of 5-ht1, 5-ht2 or 5-ht7 receptors. |
1999-10-18 |
2023-08-12 |
Not clear |
| J Yamada, Y Sugimoto, T Noma, T Yoshikaw. Effects of the non-selective 5-HT receptor agonist, 5-carboxamidotryptamine, on plasma glucose levels in rats. European journal of pharmacology. vol 359. issue 1. 1999-02-08. PMID:9831297. |
these results indicate that 5-ct-induced hyperglycemia is elicited by facilitation of adrenaline release from the adrenal gland and that 5-ct-induced hyperglycemia is mediated by the 5-ht7 receptor unrelated to 5-ht1a, 5-ht1b, 5-ht2, 5-ht3, 5-ht4 or 5-ht5 receptors. |
1999-02-08 |
2023-08-12 |
rat |
| A Sumova, E S Maywood, D Selvage, F J Ebling, M H Hasting. Serotonergic antagonists impair arousal-induced phase shifts of the circadian system of the syrian hamster. Brain research. vol 709. issue 1. 1997-01-29. PMID:8869560. |
pre-treatment of hamsters at ct 6 with the serotonergic antagonist ritanserin (1-5 mg/kg, which acts at both 5-ht2 and the putative 5-ht7 receptor, impaired the phase-advancing response to arousal at ct 10 but the drug was without effect on phase advances induced by exposure to light. |
1997-01-29 |
2023-08-12 |
rat |
| A Sumova, E S Maywood, D Selvage, F J Ebling, M H Hasting. Serotonergic antagonists impair arousal-induced phase shifts of the circadian system of the syrian hamster. Brain research. vol 709. issue 1. 1997-01-29. PMID:8869560. |
pre-treatment with a second serotonergic antagonist, ketanserin (1-5 mg/kg), which is without effect at 5-ht7 but has high affinity for 5-ht2 receptors, was also effective in attenuating the phase advancing effect of arousal at ct 10. |
1997-01-29 |
2023-08-12 |
rat |