| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Meda, M S Pepper, O Traub, K Willecke, D Gros, E Beyer, B Nicholson, D Paul, L Orc. Differential expression of gap junction connexins in endocrine and exocrine glands. Endocrinology. vol 133. issue 5. 1993-11-19. PMID:8404689. |
by immunostaining cryostat sections (indirect immunofluorescence) with antibodies against connexins (cx) 26, 32, and 43 and by hybridizing total glandular rna (northern blot) with crnas for these proteins, we have found that several endocrine glands (pituitary, parathyroid, pancreatic islets, and adrenal) express cx43, variable levels of cx26, and no cx32, whereas several exocrine glands (lacrimal gland, salivary glands, pancreas, prostate, and seminal vesicle) express high levels of cx32 and variable levels of cx26, but no cx43. |
1993-11-19 |
2023-08-12 |
rat |
| I Khan, A Hossain, G F Whitman, N H Sarkar, P G McDonoug. Differential induction of c-jun expression by PGF2-alpha in rat ovary, uterus and adrenal. Prostaglandins. vol 46. issue 2. 1993-10-28. PMID:8210443. |
rna extracted from ovary, uterus and adrenal was analyzed by northern and slot blot. |
1993-10-28 |
2023-08-12 |
rat |
| J Sakata, T Shimokubo, K Kitamura, S Nakamura, K Kangawa, H Matsuo, T Et. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochemical and biophysical research communications. vol 195. issue 2. 1993-10-12. PMID:7690563. |
rna blot analysis showed that rat adrenomedullin mrna was expressed in adrenal glands, lung, kidney, heart, spleen, duodenum and submandibular glands. |
1993-10-12 |
2023-08-12 |
human |
| O Grigoriants, L Devi, L D Fricke. Dopamine antagonist haloperidol increases carboxypeptidase E mRNA in rat neurointermediate pituitary but not in various other rat tissues. Brain research. Molecular brain research. vol 19. issue 1-2. 1993-09-30. PMID:8361339. |
rats were treated for either 1, 3, 7, 14, or 21 days with 2 mg/kg haloperidol, and then northern blot analysis performed on rna from neurointermediate pituitary, anterior pituitary, hypothalamus, striatum, cerebellum, and adrenal. |
1993-09-30 |
2023-08-12 |
rat |
| I Gantz, H Miwa, Y Konda, Y Shimoto, T Tashiro, S J Watson, J DelValle, T Yamad. Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. The Journal of biological chemistry. vol 268. issue 20. 1993-08-12. PMID:8392067. |
by northern blot analysis and in situ hybridization, this receptor is expressed primarily in the brain, but its expression is notably absent in the adrenal cortex, melanocytes, and placenta. |
1993-08-12 |
2023-08-12 |
human |
| J Hu, S Jothy, S Solomo. Localization and measurement of corticostatin-I in nonpregnant and pregnant rabbit tissues during late gestation. Endocrinology. vol 132. issue 6. 1993-07-02. PMID:8504740. |
western blot showed a single 4-kilodalton band, indicating that the antibody employed was specific for csi in spleen, intestine, adrenal, and lung, but no csi band was observed in liver. |
1993-07-02 |
2023-08-12 |
rabbit |
| T R Clarke, P A Bain, L Sha, A H Payn. Enzyme characteristics of two distinct forms of mouse 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase complementary deoxyribonucleic acids expressed in COS-1 cells. Endocrinology. vol 132. issue 5. 1993-05-25. PMID:8477648. |
in addition, the expressed 3 beta hsd iii protein analyzed by western blot has a lower mobility than the 3 beta hsd i protein, both similar in mol wt to the 3 beta hsd proteins detected in mouse liver and adrenal glands, respectively. |
1993-05-25 |
2023-08-12 |
mouse |
| S Mesiano, S H Mellon, R B Jaff. Mitogenic action, regulation, and localization of insulin-like growth factors in the human fetal adrenal gland. The Journal of clinical endocrinology and metabolism. vol 76. issue 4. 1993-05-18. PMID:8473412. |
using northern blot analysis, we found that mrna encoding igf-ii was present in high abundance in fetal adrenal glands (16-22 weeks) and barely detectable in adult adrenals, whereas mrna encoding igf-i was present in very low abundance in the fetal adrenal, but was high in adult human adrenals. |
1993-05-18 |
2023-08-12 |
human |
| D H Park, K T Kim, M U Choi, H Samanta, T H Jo. Characterization of bovine aromatic L-amino acid decarboxylase expressed in a mouse cell line: comparison with native enzyme. Brain research. Molecular brain research. vol 16. issue 3-4. 1993-04-01. PMID:1337932. |
rabbit polyclonal antiserum directed against bovine adrenal aadc recognized on western blot a single protein band (molecular mass = 55,000 dalton) in both native and recombinant bovine aadc crude extracts. |
1993-04-01 |
2023-08-11 |
mouse |
| A Miya, M Yamamoto, H Morimoto, N Tanaka, E Shin, K Karakawa, K Toyoshima, Y Ishizaka, T Mori, S Taka. Expression of the ret proto-oncogene in human medullary thyroid carcinomas and pheochromocytomas of MEN 2A. Henry Ford Hospital medical journal. vol 40. issue 3-4. 1993-02-17. PMID:1362408. |
although no transcripts were detected in the normal portion of the thyroid from one men 2a patient, faint signals were detected in normal adrenal glands by northern blot analysis, probably due to minor populations of c-cells and chromaffin cells in specimens from which mtc and pheochromocytoma might later develop. |
1993-02-17 |
2023-08-11 |
human |
| J P Mathis, I Lindber. Posttranslational processing of proenkephalin in AtT-20 cells: evidence for cleavage at a Lys-Lys site. Endocrinology. vol 131. issue 5. 1992-12-01. PMID:1425427. |
rias and western blot studies showed that at/pe clones process proenkephalin at some, but not all, lys-arg sequences in a limited processing profile reminiscent of bovine adrenal chromaffin cells. |
1992-12-01 |
2023-08-11 |
rat |
| A Penhoat, P Leduque, C Jaillard, P G Chatelain, P M Dubois, J M Sae. [Demonstration of the secretion of IGF-I and of its binding proteins by bovine adrenal fasciculata cells in culture. Immunocytochemistry, radioimmunoassay and ligand blotting]. Annales d'endocrinologie. vol 52. issue 6. 1992-10-22. PMID:1824498. |
using the method of western ligand blot, we found that the major form of igf-bp secreted by control adrenal cells is a 38-42 kda doublet protein. |
1992-10-22 |
2023-08-11 |
rabbit |
| K Racz, F Pinet, J M Gasc, T T Guyene, P Corvo. Coexpression of renin, angiotensinogen, and their messenger ribonucleic acids in adrenal tissues. The Journal of clinical endocrinology and metabolism. vol 75. issue 3. 1992-10-08. PMID:1381371. |
the relative levels of renin and angiotensinogen mrnas were determined by northern blot analysis in normal (n = 5) and pathological adrenal tissues of cortical (n = 23) and medullary (n = 10) origin. |
1992-10-08 |
2023-08-11 |
human |
| J Bednarek, J Furmaniak, N Wedlock, Y Kiso, A Baumann-Antczak, S Fowler, H Krishnan, J A Craft, B Rees Smit. Steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease. FEBS letters. vol 309. issue 1. 1992-09-30. PMID:1511745. |
absorption of the native human 55k adrenal protein with human adrenal autoantibodies prevented the subsequent reaction of the 55k protein with rabbit antibodies to 21-hydroxylase in western blot analysis. |
1992-09-30 |
2023-08-11 |
human |
| S Pang, X Yang, M Wang, R Tissot, M Nino, J Manaligod, L P Bullock, J I Maso. Inherited congenital adrenal hyperplasia in the rabbit: absent cholesterol side-chain cleavage cytochrome P450 gene expression. Endocrinology. vol 131. issue 1. 1992-07-27. PMID:1611996. |
a western blot of adrenal homogenate from normal newborn rabbits revealed a cholesterol side-chain cleavage cytochrome p450 (p450scc)-immunoreactive species (mol wt, 53 x 10(3), but this species was absent in cah adrenals; cah adrenals had a normal adrenodoxin and intensified 17 alpha-hydroxylase cytochrome p450 (p450(17)alpha) band compared to normal adrenals. |
1992-07-27 |
2023-08-11 |
human |
| O Winqvist, F A Karlsson, O Kämp. 21-Hydroxylase, a major autoantigen in idiopathic Addison's disease. Lancet (London, England). vol 339. issue 8809. 1992-07-21. PMID:1351548. |
we used high-resolution western blot analysis of an adrenal microsomal fraction to investigate the target of these antibodies. |
1992-07-21 |
2023-08-11 |
human |
| K Kohara, K B Brosnihan, C M Ferrario, A Milste. Peripheral and central angiotensin II regulates expression of genes of the renin-angiotensin system. The American journal of physiology. vol 262. issue 5 Pt 1. 1992-06-25. PMID:1317109. |
we measured angiotensinogen mrna in liver, adrenal glands, and brain (hypothalamus and lower brain stem), renin mrna in the kidney, and angiotensin-converting enzyme (ace) mrna in the lung and testis by northern blot analysis. |
1992-06-25 |
2023-08-11 |
rat |
| A Ogo, M Haji, T Yanase, K Kato, H Nawat. The modification and expression of 21-hydroxylase gene in normal human adrenal gland and adrenal cancer. Journal of endocrinological investigation. vol 14. issue 10. 1992-04-24. PMID:1687042. |
southern blot analysis with restriction enzyme eco ri revealed major fragments at 18, 13 and 9 kilobase (kb) in normal adrenal glands. |
1992-04-24 |
2023-08-11 |
human |
| A Ogo, M Haji, T Yanase, K Kato, H Nawat. The modification and expression of 21-hydroxylase gene in normal human adrenal gland and adrenal cancer. Journal of endocrinological investigation. vol 14. issue 10. 1992-04-24. PMID:1687042. |
by northern blot analysis, there was difference of signal intensity of hybridizing mrna between the adrenal cancers and normal adrenal glands. |
1992-04-24 |
2023-08-11 |
human |
| R Takayanagi, K Ohnaka, Y Sakai, R Nakao, T Yanase, M Haji, T Inagami, H Furuta, D F Gou, M Nakamut. Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor. Biochemical and biophysical research communications. vol 183. issue 2. 1992-04-21. PMID:1550596. |
the expression of the ang ii receptor mrna was detected in human liver, lung, adrenal and adrenocortical adenomas but not in adrenomedullary tumor, pheochromocytoma, by northern blot analysis. |
1992-04-21 |
2023-08-11 |
human |