| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shiv Verma, Vaibhav Singh, VijayKrishna Nagampalli, Lee E Ponsky, Chiang-Shan R Li, Herta Chao, Sanjay Gupt. Ligand-gated ion channels as potential biomarkers for ADT-mediated cognitive decline in prostate cancer patients. Molecular carcinogenesis. 2024-03-14. PMID:38482990. |
gene-disease association assigned forgetfulness, intellectual disability, visuospatial deficit, bipolar disorder, and other neurocognitive impairment with upregulation of type-1 angiotensin ii receptor, brain-derived neurotrophic factor, gaba type b receptor subunit 2 (gabbr2), gabra3, gabra5, gabrb1, glycine receptor beta, glutamate ionotropic receptor n-methyl-d-aspartate receptor (nmda) type subunit 1, glutamate ionotropic receptor nmda type subunit 2d, 5-hydroxytryptamine receptor 1d, interferon beta 1, and nuclear receptor subfamily 3 group c member 1 as top differentially expressed genes. |
2024-03-14 |
2024-03-16 |
human |
| Judith R Homberg, Paola Brivio, Corina U Greven, Francesca Calabres. Individuals being high in their sensitivity to the environment: are sensitive period changes in play? Neuroscience and biobehavioral reviews. 2024-02-28. PMID:38417743. |
key genes that contribute to individual differences in environmental sensitivity are the serotonin transporter, dopamine d4 receptor and brain-derived neurotrophic factor genes. |
2024-02-28 |
2024-03-02 |
Not clear |
| Ahmadali Baghaei, Mojtaba Yousefi Zoshk, Mohsen Hosseini, Hossein Fasihi, Ehsan Nassireslami, Sevda Shayesteh, Reza Laripour, Aynaz Eslami Amoli, Reza Heidari, Mohsen Chamanar. Prominent genetic variants and epigenetic changes in post-traumatic stress disorder among combat veterans. Molecular biology reports. vol 51. issue 1. 2024-02-23. PMID:38393604. |
meanwhile, the variations in catecholamines-related genes, serotonin transporter and receptors, brain-derived neurotrophic factor, inflammatory factors, and apolipoprotein e are the most prominent candidates. |
2024-02-23 |
2024-02-25 |
Not clear |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
alterations of learning and memory are accompanied by alterations in the expression of 5-ht receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. |
2023-09-15 |
2023-10-07 |
rat |
| Ivan Mirko Cremone, Benedetta Nardi, Giulia Amatori, Lionella Palego, Dario Baroni, Danila Casagrande, Enrico Massimetti, Laura Betti, Gino Giannaccini, Liliana Dell'Osso, Barbara Carpit. Unlocking the Secrets: Exploring the Biochemical Correlates of Suicidal Thoughts and Behaviors in Adults with Autism Spectrum Conditions. Biomedicines. vol 11. issue 6. 2023-06-28. PMID:37371695. |
in this framework, the aim of this study is to open the way in this field and evaluate the correlation between blood levels of serotonin, brain derived neurotrophic factor, tryptophan and its metabolites, il-6 and homocysteine levels and suicidality. |
2023-06-28 |
2023-08-14 |
Not clear |
| Srishti Vashishtha, Stefan Kloiber, Gwyneth Za. The therapygenetics of anxiety disorders. Psychiatric genetics. 2023-05-24. PMID:37222241. |
the most investigated polymorphisms were the serotonin transporter-linked polymorphic region (5-httlpr), nerve growth factor rs6330, catechol-o-methyltransferase val158met, and brain-derived neurotrophic factor val166met. |
2023-05-24 |
2023-08-14 |
Not clear |
| Zhengyang Quan, Hui Li, Zhenzhen Quan, Hong Qin. Appropriate Macronutrients or Mineral Elements Are Beneficial to Improve Depression and Reduce the Risk of Depression. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108261. |
for example, excessive fat intake can lead to depression, with possible mechanisms including inflammation, increased oxidative stress, reduced synaptic plasticity, and decreased expression of 5-hydroxytryptamine (5-ht), brain derived neurotrophic factor (bdnf), postsynaptic density protein 95(psd-95), etc. |
2023-04-28 |
2023-08-14 |
Not clear |
| Qiaoyi Cui, Wei We. Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. JPMA. The Journal of the Pakistan Medical Association. vol 73. issue 4. 2023-04-13. PMID:37052005. |
post treatment assessment revealed that after treatment, national institutes of health stroke scale scores, hamilton depression rating scale scores, serum 5-hydroxytryptamine and brain-derived neurotrophic factor levels of group b were lower than those of group a (all p<0.001). |
2023-04-13 |
2023-08-14 |
Not clear |
| Qiaoyi Cui, Wei We. Comparison of the efficacy of Trazodone hydrochloride tablets alone and in combination with press-needles in the treatment of post-stroke depression. JPMA. The Journal of the Pakistan Medical Association. vol 73. issue 4. 2023-04-13. PMID:37052005. |
it can be because the combination better promotes the increase of 5-hydroxytryptamine and brain-derived neurotrophic factor. |
2023-04-13 |
2023-08-14 |
Not clear |
| Hyunji Cho, Miyea Jo, Haemin Oh, Yunjung Lee, Yongsoon Par. Synergistic antidepressant-like effect of n-3 polyunsaturated fatty acids and probiotics through the brain-gut axis in rats exposed to chronic mild stress. The Journal of nutritional biochemistry. 2023-03-24. PMID:36963732. |
n-3 pufa and probiotics upregulated the brain serotonergic pathway through serotonin levels and expression of brain-derived neurotrophic factor, phosphorylated camp response binding protein, and 5-hydroxytryptamine 1a receptor while downregulating the gut serotonergic pathway. |
2023-03-24 |
2023-08-14 |
rat |
| Ghulam Yahya Amiry, Murtaza Haidary, Hassan Azhdari-Zarmehri, Farimah Beheshti, S Mohammad Ahmadi-Soleiman. Omega-3 fatty acids prevent nicotine withdrawal-induced exacerbation of anxiety and depression by affecting oxidative stress balance, inflammatory response, BDNF and serotonin metabolism in rats. European journal of pharmacology. 2023-03-03. PMID:36868293. |
then, animals were euthanized and the cortical concentrations of oxidative stress markers, inflammatory indices, brain-derived neurotrophic factor, serotonin and the enzymatic activity of monoamine oxidase-a were measured. |
2023-03-03 |
2023-08-14 |
rat |
| Reiji Yoshimura, Naomichi Okamoto, Enkmurun Chibaatar, Tomoya Natsuyama, Atsuko Ikenouch. The Serum Brain-Derived Neurotrophic Factor Increases in Serotonin Reuptake Inhibitor Responders Patients with First-Episode, Drug-Naïve Major Depression. Biomedicines. vol 11. issue 2. 2023-02-25. PMID:36831119. |
the serum brain-derived neurotrophic factor increases in serotonin reuptake inhibitor responders patients with first-episode, drug-naïve major depression. |
2023-02-25 |
2023-08-14 |
Not clear |
| Justyna Turek, Łukasz Gąsio. Estrogen fluctuations during the menopausal transition are a risk factor for depressive disorders. Pharmacological reports : PR. 2023-01-13. PMID:36639604. |
equally discussed are the possible mechanisms underlying these effects, including the role of estrogen in modulating brain-derived neurotrophic factor activity, serotonin neurotransmission, as well as the induction of inflammatory response and changes in metabolic activity, are discussed. |
2023-01-13 |
2023-08-14 |
Not clear |
| Mohammad Bani-Ahmad, Marah Ahmad, Marya Obeidat, Mousa Barqaw. The modulation of Plasma Levels of Dopamine, Serotonin, and Brain-derived neurotrophic factor in response to variation in iron availability. Acta bio-medica : Atenei Parmensis. vol 93. issue 6. 2022-12-19. PMID:36533769. |
the modulation of plasma levels of dopamine, serotonin, and brain-derived neurotrophic factor in response to variation in iron availability. |
2022-12-19 |
2023-08-14 |
Not clear |
| Michele Linsalata, Laura Prospero, Giuseppe Riezzo, Antonella Orlando, Benedetta D'Attoma, Antonia Ignazzi, Francesco Russ. Somatization is associated with altered serum levels of vitamin D, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2022-12-15. PMID:36520620. |
somatization is associated with altered serum levels of vitamin d, serotonin, and brain-derived neurotrophic factor in patients with predominant diarrhea irritable bowel syndrome. |
2022-12-15 |
2023-08-14 |
Not clear |
| Doaa M Samy, Dalia Kamal Mostafa, Samar R Saleh, Passainte S Hassaan, Teshreen M Zeitoun, Gamal A G Ammar, Nahed H Elsokkar. Carnosic Acid Mitigates Depression-Like Behavior in Ovariectomized Mice via Activation of Nrf2/HO-1 Pathway. Molecular neurobiology. 2022-11-04. PMID:36331794. |
ca treatment alleviated depressive behavior, induced the expression of nrf2, ho-1, thioredoxin-1, and brain-derived neurotrophic factor, and enhanced serotonin levels. |
2022-11-04 |
2023-08-14 |
mouse |
| Ryan E Ross, Catherine J VanDerwerker, Michael E Saladin, Chris M Gregor. The role of exercise in the treatment of depression: biological underpinnings and clinical outcomes. Molecular psychiatry. 2022-10-17. PMID:36253441. |
acute bouts of exercise have been shown to transiently modulate circulating levels of serotonin and norepinephrine, brain-derived neurotrophic factor, and a variety of immuno-inflammatory mechanisms in clinical cohorts with depression. |
2022-10-17 |
2023-08-14 |
Not clear |
| Iris Šalamon Arčan, Katarina Kouter, Alja Videtič Pask. Depressive disorder and antidepressants from an epigenetic point of view. World journal of psychiatry. vol 12. issue 9. 2022-10-03. PMID:36186508. |
among the most studied epigenetic modifications in depressive disorder is dna methylation, with findings centered on the brain-derived neurotrophic factor gene, the glucocorticoid receptor gene, and the serotonin transporter gene. |
2022-10-03 |
2023-08-14 |
Not clear |
| Ana Salomé Correia, Nuno Val. Tryptophan Metabolism in Depression: A Narrative Review with a Focus on Serotonin and Kynurenine Pathways. International journal of molecular sciences. vol 23. issue 15. 2022-08-12. PMID:35955633. |
thus, this narrative review aims to explore tryptophan metabolism (particularly in the serotonin and kynurenine pathways) in depression, starting with a global overview about these topics and ending with the focus on these pathways in neuroinflammation, stress, microbiota, and brain-derived neurotrophic factor regulation in this disease. |
2022-08-12 |
2023-08-14 |
human |
| Nouf M Alyami, Saba Abdi, Hanadi M Alyami, Rafa Almee. Proanthocyanidins alleviate pentylenetetrazole-induced epileptic seizures in mice via the antioxidant activity. Neurochemical research. 2022-07-15. PMID:35838827. |
moreover, ache activity, da, ne, 5-ht, brain-derived neurotrophic factor levels, and gene expression of nrf2 have decreased in the hippocampal tissue of ptz exposed mice. |
2022-07-15 |
2023-08-14 |
mouse |