| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Concetta Crisafulli, Chiara Fabbri, Stefano Porcelli, Antonio Drago, Edoardo Spina, Diana De Ronchi, Alessandro Serrett. Pharmacogenetics of antidepressants. Frontiers in pharmacology. vol 2. 2011-07-14. PMID:21687501. |
they include the cytochrome p450 superfamily, the p-glycoprotein (abcb1), the tryptophan hydroxylase, the catechol-o-methyltransferase, the monoamine oxidase a, the serotonin transporter (5-httlpr), the norepinephrine transporter, the dopamine transporter, variants in the 5-hydroxytryptamine receptors (5-ht1a, 5-ht2a, 5-ht3a, 5-ht3b, and 5-ht6), adrenoreceptor beta-1 and alpha-2, the dopamine receptors (d2), the g protein beta 3 subunit, the corticotropin releasing hormone receptors (crhr1 and crhr2), the glucocorticoid receptors, the c-amp response-element binding, and the brain-derived neurotrophic factor. |
2011-07-14 |
2023-08-12 |
human |
| Catherina E M van Beijsterveldt, Christel M Middeldorp, Margarita C T Slof-Op't Landt, Meike Bartels, Jouke-Jan Hottenga, H Eka D Suchiman, P Eline Slagboom, Dorret I Boomsm. Influence of candidate genes on attention problems in children: a longitudinal study. Behavior genetics. vol 41. issue 1. 2011-06-28. PMID:21049304. |
this study investigated the effect of 26 single nucleotide polymorphisms (snps) in genes encoding for serotonin receptors 2a (htr2a), catechol-o-methyltransferase (comt), tryptophane hydroxylase type 2 (tph2), and brain derived neurotrophic factor (bdnf). |
2011-06-28 |
2023-08-12 |
Not clear |
| Sooyoung Bhang, Joon-Ho Ahn, Sam-Wook Cho. Brain-derived neurotrophic factor and serotonin transporter gene-linked promoter region genes alter serum levels of brain-derived neurotrophic factor in humans. Journal of affective disorders. vol 128. issue 3. 2011-04-25. PMID:20674984. |
brain-derived neurotrophic factor and serotonin transporter gene-linked promoter region genes alter serum levels of brain-derived neurotrophic factor in humans. |
2011-04-25 |
2023-08-12 |
human |
| E Nederhof, E M C Bouma, H Riese, O M Laceulle, J Ormel, A J Oldehinke. Evidence for plasticity genotypes in a gene-gene-environment interaction: the TRAILS study. Genes, brain, and behavior. vol 9. issue 8. 2011-03-02. PMID:20738408. |
the purpose was to study how functional polymorphisms in the brain derived neurotrophic factor gene (bdnf val66met) and the serotonin transporter gene linked promotor region (5-httlpr) interact with childhood adversities in predicting effortful control. |
2011-03-02 |
2023-08-12 |
Not clear |
| Justine M Gatt, Charles B Nemeroff, Peter R Schofield, Robert H Paul, C Richard Clark, Evian Gordon, Leanne M William. Early life stress combined with serotonin 3A receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression. Biological psychiatry. vol 68. issue 9. 2011-02-15. PMID:20728877. |
early life stress combined with serotonin 3a receptor and brain-derived neurotrophic factor valine 66 to methionine genotypes impacts emotional brain and arousal correlates of risk for depression. |
2011-02-15 |
2023-08-12 |
Not clear |
| C M Middeldorp, M C T Slof-Op 't Landt, S E Medland, C E M van Beijsterveldt, M Bartels, G Willemsen, J-J Hottenga, E J C de Geus, H E D Suchiman, C V Dolan, M C Neale, P E Slagboom, D I Boomsm. Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? Genes, brain, and behavior. vol 9. issue 7. 2011-02-08. PMID:20633049. |
this study investigated the effect of 45 single nucleotide polymorphisms (snps) in genes encoding for serotonin receptors 1a, 1d, 2a, catechol-o-methyltransferase (comt), tryptophane hydroxylase type 2 (tph2), brain derived neurotrophic factor (bdnf), plexina2 and regulators of g-protein-coupled signaling (rgs) 2, 4, 16. |
2011-02-08 |
2023-08-12 |
human |
| V E Golimbet, O S Brusov, M I Factor, G P Zlobina, T V Lezheĭko, O M Lavrushina, E A Petrova, M A Savina, V I Skvortsov. [Interaction effect of serotonin transporter gene and brain-derived neurotrophic factor on the platelet serotonin content in stroke patients]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 110. issue 4 Suppl 2. 2010-12-10. PMID:20738025. |
[interaction effect of serotonin transporter gene and brain-derived neurotrophic factor on the platelet serotonin content in stroke patients]. |
2010-12-10 |
2023-08-12 |
Not clear |
| Angela M Devlin, Ursula Brain, Jehannine Austin, Tim F Oberlande. Prenatal exposure to maternal depressed mood and the MTHFR C677T variant affect SLC6A4 methylation in infants at birth. PloS one. vol 5. issue 8. 2010-11-04. PMID:20808944. |
the methylation status of slc6a4, which encodes the transmembrane serotonin transporter, and bdnf, which encodes brain derived neurotrophic factor, were assessed because of their potential role in behaviour. |
2010-11-04 |
2023-08-12 |
Not clear |
| Esther Nederhof, Esther M C Bouma, Albertine J Oldehinkel, Johan Orme. Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: the TRAILS study. Biological psychiatry. vol 68. issue 2. 2010-10-12. PMID:20553751. |
interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: the trails study. |
2010-10-12 |
2023-08-12 |
Not clear |
| Esther Nederhof, Esther M C Bouma, Albertine J Oldehinkel, Johan Orme. Interaction between childhood adversity, brain-derived neurotrophic factor val/met and serotonin transporter promoter polymorphism on depression: the TRAILS study. Biological psychiatry. vol 68. issue 2. 2010-10-12. PMID:20553751. |
the three-way interaction between the functional polymorphism in the serotonin transporter gene linked promoter region, the val66met polymorphism in the brain-derived neurotrophic factor gene, and childhood adversity in the prediction of depression in children, reported by kaufman and colleagues in 2006, has only been confirmed in adult samples. |
2010-10-12 |
2023-08-12 |
Not clear |
| Koji Otsuki, Shusaku Uchida, Yusuke Wakabayashi, Toshio Matsubara, Teruyuki Hobara, Hiromasa Funato, Yoshifumi Watanab. Aberrant REST-mediated transcriptional regulation in major depressive disorder. Journal of psychiatric research. vol 44. issue 6. 2010-08-26. PMID:19846118. |
rest has many target genes, including corticotropin releasing hormone (crh), brain-derived neurotrophic factor, serotonin 1a receptor, which are suggested to be involved in the pathophysiology of depression and the action of antidepressants. |
2010-08-26 |
2023-08-12 |
Not clear |
| Jens Drachmann Bukh, Camilla Bock, Maj Vinberg, Thomas Werge, Ulrik Gether, Lars Vedel Kessin. No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 20. issue 5. 2010-06-14. PMID:20022223. |
further, we genotyped nine polymorphisms in the genes encoding the serotonin transporter, brain derived neurotrophic factor, catechol-o-methyltransferase, angiotensin converting enzyme, tryptophan hydroxylase, and the serotonin receptors 1a, 2a, and 2c. |
2010-06-14 |
2023-08-12 |
Not clear |
| Francesca Calabrese, Raffaella Molteni, Annamaria Cattaneo, Flavia Macchi, Giorgio Racagni, Massimo Gennarelli, Bart A Ellenbroek, Marco A Riv. Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Molecular pharmacology. vol 77. issue 5. 2010-05-28. PMID:20159945. |
long-term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. |
2010-05-28 |
2023-08-12 |
rat |
| Refaat Tabagh, Christian R Andres, Sylviane Védrine, Catherine Cherpi-Antar, Rose-Anne Thepault, Laurence Mignon, Diane Dufour-Rainfray, Claude Moraine, Patrick Vourc'. Study of the serotonin transporter (SLC6A4) and BDNF genes in French patients with non syndromic mental deficiency. BMC medical genetics. vol 11. 2010-04-08. PMID:20175892. |
the aim of the current paper is to determine whether particular alleles or genotypes of two crucial genes of these systems, the serotonin transporter gene (slc6a4) and the brain-derived neurotrophic factor gene (bdnf), are associated with mental deficiency (md). |
2010-04-08 |
2023-08-12 |
Not clear |
| Atsuko Ikenouchi-Sugita, Yumiko Toyohira, Reiji Yoshimura, Susumu Ueno, Masato Tsutsui, Jun Nakamura, Nobuyuki Yanagihar. Opposite effects of milnacipran, a serotonin norepinephrine reuptake inhibitor, on the levels of nitric oxide and brain-derived neurotrophic factor in mouse brain cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 380. issue 6. 2010-03-30. PMID:19894036. |
opposite effects of milnacipran, a serotonin norepinephrine reuptake inhibitor, on the levels of nitric oxide and brain-derived neurotrophic factor in mouse brain cortex. |
2010-03-30 |
2023-08-12 |
mouse |
| Dharmendra B Goswami, Warren L May, Craig A Stockmeier, Mark C Austi. Transcriptional expression of serotonergic regulators in laser-captured microdissected dorsal raphe neurons of subjects with major depressive disorder: sex-specific differences. Journal of neurochemistry. vol 112. issue 2. 2010-02-05. PMID:19878438. |
candidates that regulate 5-ht synthesis and neuronal activity of 5-ht neurons include intrinsic regulators such as tryptophan hydroxylase 2, 5-ht autoreceptors, 5-ht transporter and transcription factors, as well as afferent regulators such as estrogen and brain-derived neurotrophic factor. |
2010-02-05 |
2023-08-12 |
human |
| Sara Bozzini, Patrick Gambelli, Chiara Boiocchi, Sandra Schirinzi, Rossana Falcone, Paola Buzzi, Cesare Storti, Colomba Falcon. Coronary artery disease and depression: possible role of brain-derived neurotrophic factor and serotonin transporter gene polymorphisms. International journal of molecular medicine. vol 24. issue 6. 2010-02-04. PMID:19885623. |
coronary artery disease and depression: possible role of brain-derived neurotrophic factor and serotonin transporter gene polymorphisms. |
2010-02-04 |
2023-08-12 |
human |
| Alexandra Schosser, Siegfried Kaspe. The role of pharmacogenetics in the treatment of depression and anxiety disorders. International clinical psychopharmacology. vol 24. issue 6. 2010-01-07. PMID:19738481. |
two functional polymorphisms of the serotonin transporter gene, 5-httlpr and stin2 have been investigated in a large number of pharmacogenetic studies of depression; other candidate genes include serotonin receptor genes, brain-derived neurotrophic factor, p-glycoprotein (located in the blood-brain barrier), g-proteins, tph1 and tph2, maoa, the noradrenaline transporter gene, fkbp5, or cytochrome p450 (cyp450) genes. |
2010-01-07 |
2023-08-12 |
Not clear |
| Vera Golimbet, Margarita Alfimova, Galina Korovaitseva, Lilia I Abramova, Vasily G Kale. Emotional distress in parents of psychotic patients is modified by serotonin transporter gene (5-HTTLPR)--brain-derived neurotrophic factor gene interactions. The Spanish journal of psychology. vol 12. issue 2. 2009-12-03. PMID:19899670. |
emotional distress in parents of psychotic patients is modified by serotonin transporter gene (5-httlpr)--brain-derived neurotrophic factor gene interactions. |
2009-12-03 |
2023-08-12 |
Not clear |
| Susanne Henningsson, Jacqueline Borg, Johan Lundberg, Jessica Bah, Mats Lindström, Erik Ryding, Hristina Jovanovic, Tomoyuki Saijo, Makoto Inoue, Ingmar Rosén, Lil Träskman-Bendz, Lars Farde, Elias Eriksso. Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men. Biological psychiatry. vol 66. issue 5. 2009-10-21. PMID:19500776. |
genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1a receptor availability in men. |
2009-10-21 |
2023-08-12 |
Not clear |