| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lorena Teodoro de Castro Cassanta, Virmondes Rodrigues, Jose Roberto Violatti-Filho, Benedito Alves Teixeira Neto, Vinícius Marques Tavares, Eduarda Castelo Branco Araujo Bernal, Danila Malheiros Souza, Marcelo Sivieri Araujo, Sanivia Aparecida de Lima Pereira, Denise Bertulucci Rocha Rodrigue. Modulation of Matrix Metalloproteinase 14, Tissue Inhibitor of Metalloproteinase 3, Tissue Inhibitor of Metalloproteinase 4, and Inducible Nitric Oxide Synthase in the Development of Periapical Lesions. Journal of endodontics. vol 43. issue 7. 2018-05-11. PMID:28527839. |
therefore, because of the chronic inflammatory state of these lesions, the aim of this study was to evaluate the in situ expression of matrix metalloproteinase (mmp)-14 and -19, tissue inhibitor of metalloproteinase (timp)-3 and -4, cd68, and inducible nitric oxide synthase (inos) in periapical cysts and granulomas. |
2018-05-11 |
2023-08-13 |
Not clear |
| Chunling Huang, Ling Zhang, Ying Shi, Hao Yi, Yongli Zhao, Jason Chen, Carol A Pollock, Xin-Ming Che. The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy. PloS one. vol 13. issue 2. 2018-04-20. PMID:29425253. |
albuminuria was assessed, inflammatory markers (cd68, f4/80) and extracellular matrix deposition (type i collagen and fibronectin) in the kidneys were examined. |
2018-04-20 |
2023-08-13 |
mouse |
| Xiaoning Han, Xi Lan, Qiang Li, Yufeng Gao, Wei Zhu, Tian Cheng, Takayuki Maruyama, Jian Wan. Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 36. issue 6. 2017-08-09. PMID:26661165. |
ep3 receptor inhibition reduced lesion volume, neurologic deficit, cell death, matrix metalloproteinase-9 activity, neutrophil infiltration, and the number of cd68(+) microglia, but increased the number of ym-1(+) m2 microglia. |
2017-08-09 |
2023-08-13 |
mouse |
| Sepanta Hosseinpour, Fatemeh Mashhadiabbas, Mitra Ghazizadeh Ahsai. Diagnostic Biomarkers in Oral Verrucous Carcinoma: A Systematic Review. Pathology oncology research : POR. vol 23. issue 1. 2017-03-22. PMID:27924463. |
among cell surface and extracellular matrix biomarkers tissue biomarkers, matrix metalloproteinase (mmp)-2, -9, cd31 and cd68 seem to be useful for differentiation of ovc and oscc and glucose transporter-1 (glut-1) can help in differentiation of ovc from oral epithelial dysplasia. |
2017-03-22 |
2023-08-13 |
human |
| Sebastian Fischer, Wolf Mueller, Matthias Schulte, Jurij Kiefer, Christoph Hirche, Sina Heimer, Eva Köllensperger, Günter Germann, Matthias A Reichenberge. Multiple extracorporeal shock wave therapy degrades capsular fibrosis after insertion of silicone implants. Ultrasound in medicine & biology. vol 41. issue 3. 2016-01-04. PMID:25619782. |
at 35 d (n = 6) and 100 d (n = 6) after insertion, silicone implants and surrounding capsule tissue were removed and prepared for histologic and immunohistochemical analysis, as well as polymerase chain reaction (ccl2, cd68, transforming growth factor β1, matrix metalloproteinase 2). |
2016-01-04 |
2023-08-13 |
rat |
| Vashendriya V V Hira, Kimberley J Ploegmakers, Frederieke Grevers, Urška Verbovšek, Carlos Silvestre-Roig, Eleonora Aronica, Wikky Tigchelaar, Tamara Lah Turnšek, Remco J Molenaar, Cornelis J F Van Noorde. CD133+ and Nestin+ Glioma Stem-Like Cells Reside Around CD31+ Arterioles in Niches that Express SDF-1α, CXCR4, Osteopontin and Cathepsin K. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 63. issue 7. 2015-09-04. PMID:25809793. |
leukocyte-related markers, such as cd68, macrophage matrix metalloprotease-9, cd177 and neutrophil elastase were often but not always detected in the niches. |
2015-09-04 |
2023-08-13 |
human |
| David M Hasan, Robert M Starke, He Gu, Katina Wilson, Yi Chu, Nohra Chalouhi, Donald D Heistad, Frank M Faraci, Curt D Sigmun. Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo. Hypertension (Dallas, Tex. : 1979). vol 66. issue 1. 2015-08-25. PMID:25916724. |
dominant-negative smooth muscle-specific pparγ, but not dominant-negative endothelial-specific pparγ, resulted in significant decreases in expression of genes encoding cullin3, kelch-like ech-associated protein 1, and nuclear factor (erythroid-derived 2)-like 2, along with significant increases in tumor necrosis factor-α, monocyte chemoattractant protein-1, chemokine (c-x-c motif) ligand 1, cd68, matrix metalloproteinase-3, -9, and -13. |
2015-08-25 |
2023-08-13 |
mouse |
| Jamile Gomes Conceição, Clarissa Araújo Gurgel, Eduardo Antônio Gonçalves Ramos, Flávia Caló De Aquino Xavier, Caroline Brandi Schlaepfer-Sales, Maria Cristina Teixeira Cangussu, Patrícia Ramos Cury, Luciana Maria Pedreira Ramalho, Jean Nunes Dos Santo. Oral mucoceles: a clinical, histopathological and immunohistochemical study. Acta histochemica. vol 116. issue 1. 2015-05-14. PMID:23726142. |
the expression of mast cell tryptase, cd68, mmp-1 (matrix metalloproteinase-1), mmp-9 (matrix metalloproteinase-9) and cd34 was investigated immunohistochemically in 32 cases. |
2015-05-14 |
2023-08-12 |
Not clear |
| Shujun Sun, Yonghong Sun, Limin Zhao, Jianming Zhou, Hongzeng Wang, Meihong Gu. [The expression of tumor related macrophages and matrix solution element in laryngeal squamous carcinoma tissue and the relationship with tumor microvascular density]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 28. issue 2. 2014-12-22. PMID:24738320. |
to study the expression of cd68 antibody marked tumor associated macrophage tams and matrix solution element mmp-7 in laryngeal squamous carcinoma tissue and the relationship with clinicopathological parameters, so that to explore the relationship between the expression of the two molecular markers and laryngeal cancer tissue microvascular density (mvd). |
2014-12-22 |
2023-08-13 |
Not clear |
| Katsuaki Kanbe, Junji Chiba, Atsushi Nakamur. Inhibition of JNK in synovium by treatment with golimumab in rheumatoid arthritis. Rheumatology international. vol 34. issue 1. 2014-10-13. PMID:23334372. |
synovium samples from both groups were assessed by hematoxylin and eosin (he) staining and analyzed for expression of tumor necrosis factor-α (tnf-α), interleukin-6 (il-6), matrix metalloproteinase-3 (mmp-3), cd4 (t cells), cd8 (t cells), cd20 (b cells), cd68 (macrophages), receptor activator of nuclear (kappa) b ligand (rankl), bromodeoxyuridine (brdu), cd29 (β-1 integrin), phospho-p38 mapk (tyr180/tyr182), phospho-p44/42 mapk (erk1/erk2), and phospho-c-jun n-terminal kinase (jnk), by an immunohistological examination. |
2014-10-13 |
2023-08-12 |
Not clear |
| Takeshi Kanaumi, Ivan Milenkovic, Homa Adle-Biassette, Eleonora Aronica, Gabor G Kovac. Non-neuronal cell responses differ between normal and Down syndrome developing brains. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 8. 2014-07-23. PMID:24113258. |
we evaluated immunoreactivity for cd68 (macrophage), hla-dr (microglia), olig2 and tppp/p25 (oligodendroglia), and gfap (astroglia) in the germinal matrix (gm), temporal lobe white matter (tewm) and hippocampus from 14 weeks of gestations to newborn in 28 ds patients and 30 age-matched controls. |
2014-07-23 |
2023-08-12 |
Not clear |
| Victoria L Gadd, Richard Skoien, Elizabeth E Powell, Kevin J Fagan, Clay Winterford, Leigh Horsfall, Katharine Irvine, Andrew D Clousto. The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. Hepatology (Baltimore, Md.). vol 59. issue 4. 2014-06-09. PMID:24254368. |
the portal infiltrate was characterized by immunostaining nafld liver biopsy sections (n = 33) for broad leukocyte subset markers (cd68, cd3, cd8, cd4, cd20, and neutrophil elastase) and selected inflammatory markers (matrix metalloproteinase 9 and interleukin [il]-17). |
2014-06-09 |
2023-08-12 |
human |
| Katsuaki Kanbe, Junji Chiba, Atsushi Nakamur. Immunohistological analysis of synovium treated with abatacept in rheumatoid arthritis. Rheumatology international. vol 33. issue 7. 2014-01-30. PMID:22212411. |
the synovium samples from both group were assessed by hematoxylin and eosin (he) staining and analyzed for their expression of tumor necrosis factor-α (tnf-α), interleukin-6 (il-6), matrix metalloproteinase-3 (mmp-3), cd20, cd68, vascular endothelial growth factor (vegf), cd4, cd8, cd28, cd80, and cd86 by an immunohistological examination. |
2014-01-30 |
2023-08-12 |
Not clear |
| Chuan-Jie Xu, Tetuo Mikami, Takatoshi Nakamura, Tomoko Tsuruta, Norihiro Nakada, Nobuyuki Yanagisawa, Shi-Xu Jiang, Isao Okayas. Tumor budding, myofibroblast proliferation, and fibrosis in obstructing colon carcinoma: the roles of Hsp47 and basic fibroblast growth factor. Pathology, research and practice. vol 209. issue 2. 2013-08-12. PMID:23265436. |
the lesions were immunohistochemically analyzed using antibodies for pan-cytokeratin, α-smooth muscle actin, matrix metalloproteinase-7, 47-kda heat shock protein (hsp47), basic fibroblast growth factor (bfgf), myeloperoxidase, and cd68. |
2013-08-12 |
2023-08-12 |
Not clear |
| Jia-Wei Hsu, Hsuan-Cheng Huang, Shui-Tein Chen, Chi-Huey Wong, Hsueh-Fen Jua. Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation. Evidence-based complementary and alternative medicine : eCAM. vol 2011. 2012-08-23. PMID:19696196. |
furthermore, f3-treated thp-1 cells exhibited enhanced macrophage differentiation, as demonstrated by changes in cell adherence, cell cycle arrest, nbt reduction and expression of differentiation markers including cd11b, cd14, cd68, matrix metalloproteinase-9 and myeloperoxidase. |
2012-08-23 |
2023-08-12 |
human |
| Katsuaki Kanbe, Qian Chen, Atsushi Nakamura, Kaori Hob. Inhibition of MAP kinase in synovium by treatment with tocilizumab in rheumatoid arthritis. Clinical rheumatology. vol 30. issue 11. 2012-02-17. PMID:21909699. |
the synovium was observed using hematoxylin and eosin (h&e) stain and analyzed immunohistochemically for the expression of tumor necrosis factor-α (tnf-α), interleukin-6 (il-6), matrix metalloproteinase-3 (mmp-3), cd4 (t cell), cd20 (b cell), cd68 (macrophage), vascular endothelial growth factor (vegf), cd29 (β-1 integrin), phospho-p38 mapk (tyr180/tyr182), phospho-p44/42 mapk [extracellular signal-regulated kinase (erk) 1/erk2], and phospho-c-jun n-terminal kinase (jnk). |
2012-02-17 |
2023-08-12 |
Not clear |
| Haralampos Gouveris, Christina Nousia, Alexandra Giatromanolaki, Maria Riga, Michael Katotomichelakis, Jannis Papathanasiou, Jean-Baptiste Watelet, Vasilios Danielide. Immunohistological study of wound healing after submucosal radiofrequency tissue ablation of inferior nasal turbinate in a sheep model. American journal of rhinology & allergy. vol 25. issue 2. 2011-11-01. PMID:21679519. |
this study was designed to examine tissue expression of fibronectin, collagen iii, cd68, and matrix metalloproteinase (mmp) 9 in the int (ventral) after rta in sheep. |
2011-11-01 |
2023-08-12 |
Not clear |
| Willian F Zambuzzi, Katiúcia B S Paiva, Renato Menezes, Rodrigo C Oliveira, Rumio Taga, José M Granjeir. MMP-9 and CD68(+) cells are required for tissue remodeling in response to natural hydroxyapatite. Journal of molecular histology. vol 40. issue 4. 2010-03-23. PMID:19941097. |
taken together, our results suggest that xenogenic ha promotes extracellular matrix remodeling through induction of mmp-9 activity and presence of cd68(+) cells. |
2010-03-23 |
2023-08-12 |
rat |
| Maria do Socorro Aragão, Marta Rabello Piva, Cassiano Francisco Weege Nonaka, Roseana de Almeida Freitas, Lélia Batista de Souza, Leão Pereira Pint. Central giant cell granuloma of the jaws and giant cell tumor of long bones: an immunohistochemical comparative study. Journal of applied oral science : revista FOB. vol 15. issue 4. 2009-12-16. PMID:19089150. |
this study investigated whether some components of the extracellular matrix and cd68 expression may drive the differences between the central giant cell granuloma (cgcg) of the jaws and giant cell tumor (gct) of long bones, which present distinct evolution and clinical behavior. |
2009-12-16 |
2023-08-12 |
Not clear |
| Takane Suda, H Hara, M Yoshitake, T Ohbayashi, T Nakamura, T Teru. Immunohistochemical investigation of mid-dermal elastolysis with a history of erythema. The American Journal of dermatopathology. vol 30. issue 5. 2008-12-30. PMID:18806493. |
the distribution of elastin, cd68, matrix metalloproteinase (mmp)-9, and fibulin-5 was examined immunohistochemically from both erythematous and wrinkled skin. |
2008-12-30 |
2023-08-12 |
Not clear |