| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masafumi Ihara, Tuomo M Polvikoski, Ros Hall, Janet Y Slade, Robert H Perry, Arthur E Oakley, Elisabet Englund, John T O'Brien, Paul G Ince, Raj N Kalari. Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies. Acta neuropathologica. vol 119. issue 5. 2010-06-22. PMID:20091409. |
pathological diagnosis significantly affected the frontal but not temporal lobe myelin attenuation: myelin density was most reduced in vad compared to ad and dlb, which still significantly exhibited lower myelin density compared to ageing controls. |
2010-06-22 |
2023-08-12 |
Not clear |
| Rosie Watson, Andrew M Blamire, John T O'Brie. Magnetic resonance imaging in lewy body dementias. Dementia and geriatric cognitive disorders. vol 28. issue 6. 2010-04-30. PMID:19996594. |
dlb and pdd share a similar pattern of mri changes including global brain volume loss, a predominantly subcortical pattern of cerebral atrophy and structural preservation of the medial temporal lobe compared to ad. |
2010-04-30 |
2023-08-12 |
Not clear |
| Armin von Gunten, Reto Meul. Delineating dementia with lewy bodies: can magnetic resonance imaging help? Frontiers of neurology and neuroscience. vol 24. 2009-04-30. PMID:19182470. |
besides the relative sparing of medial temporal lobe structures in dlb in comparison to alzheimer's disease, no clear signature pattern of cerebral atrophy associated with dlb has been established so far. |
2009-04-30 |
2023-08-12 |
Not clear |
| E J Burton, R Barber, E B Mukaetova-Ladinska, J Robson, R H Perry, E Jaros, R N Kalaria, J T O'Brie. Medial temporal lobe atrophy on MRI differentiates Alzheimer's disease from dementia with Lewy bodies and vascular cognitive impairment: a prospective study with pathological verification of diagnosis. Brain : a journal of neurology. vol 132. issue Pt 1. 2009-03-10. PMID:19022858. |
the purpose of this study was to determine the diagnostic accuracy of medial temporal lobe atrophy (mta) on mri for distinguishing alzheimer's disease from other dementias in autopsy confirmed cases, and to determine pathological correlates of mta in alzheimer's disease, dementia with lewy bodies (dlb) and vascular cognitive impairment (vci). |
2009-03-10 |
2023-08-12 |
human |
| Michael J Firbank, Andrew M Blamire, Mani S Krishnan, Andrew Teodorczuk, Philip English, Anil Gholkar, Roger M Harrison, John T O'Brie. Diffusion tensor imaging in dementia with Lewy bodies and Alzheimer's disease. Psychiatry research. vol 155. issue 2. 2007-09-06. PMID:17408930. |
we hypothesized that there would be disease specific alterations revealed by diffusion tensor imaging with ad showing temporal lobe and dlb more parietal changes. |
2007-09-06 |
2023-08-12 |
human |
| Jennifer L Whitwell, Stephen D Weigand, Maria M Shiung, Bradley F Boeve, Tanis J Ferman, Glenn E Smith, David S Knopman, Ronald C Petersen, Eduardo E Benarroch, Keith A Josephs, Clifford R Jac. Focal atrophy in dementia with Lewy bodies on MRI: a distinct pattern from Alzheimer's disease. Brain : a journal of neurology. vol 130. issue Pt 3. 2007-04-16. PMID:17267521. |
on direct comparison between the two groups, the alzheimer's disease group showed greater loss in the medial temporal lobe and inferior temporal regions than the dlb group. |
2007-04-16 |
2023-08-12 |
Not clear |
| David Weisman, Ian McKeit. Dementia with Lewy bodies. Seminars in neurology. vol 27. issue 1. 2007-04-03. PMID:17226740. |
additional supportive features that commonly occur in dlb, but with lower specificity, include repeated falls and syncope, transient, unexplained loss of consciousness, severe autonomic dysfunction, hallucinations in other modalities, systematized delusions, depression, relative preservation of medial temporal lobe structures on structural neuroimaging, reduced occipital activity on functional neuroimaging, prominent slow wave activity on electroencephalogram, and low uptake myocardial scintigraphy. |
2007-04-03 |
2023-08-12 |
Not clear |
| Paul M Kemp, Sandra A Hoffmann, Clive Holmes, Livia Bolt, Tony Ward, Robin B Holmes, John S Flemin. The contribution of statistical parametric mapping in the assessment of precuneal and medial temporal lobe perfusion by 99mTc-HMPAO SPECT in mild Alzheimer's and Lewy body dementia. Nuclear medicine communications. vol 26. issue 12. 2006-04-10. PMID:16264357. |
to assess the role of 99mtc-hexamethylpropyleneamine oxime single-photon emission computed tomography (99mtc-hmpao spect) imaging of the precuneus and medial temporal lobe in the individual patient with mild alzheimer's disease and dementia with lewy bodies (dlb) using statistical parametric mapping and visual image interpretation. |
2006-04-10 |
2023-08-12 |
Not clear |
| C W C Tam, E J Burton, I G McKeith, D J Burn, J T O'Brie. Temporal lobe atrophy on MRI in Parkinson disease with dementia: a comparison with Alzheimer disease and dementia with Lewy bodies. Neurology. vol 64. issue 5. 2006-02-09. PMID:15753423. |
to investigate the extent of medial temporal lobe atrophy (mta) on mri in parkinson disease (pd) with and without dementia compared with alzheimer disease (ad) and dementia with lewy bodies (dlb) and to determine whether mta correlates with cognitive impairment in pd and pd dementia (pdd). |
2006-02-09 |
2023-08-12 |
Not clear |
| M Bozzali, A Falini, M Cercignani, F Baglio, E Farina, M Alberoni, P Vezzulli, F Olivotto, F Mantovani, T Shallice, G Scotti, N Canal, R Nemn. Brain tissue damage in dementia with Lewy bodies: an in vivo diffusion tensor MRI study. Brain : a journal of neurology. vol 128. issue Pt 7. 2005-07-18. PMID:15817515. |
the modest involvement of the temporal lobe fits with the relative preservation of global neuropsychological measures and memory tasks in the early stage of dlb. |
2005-07-18 |
2023-08-12 |
Not clear |
| Sid Gilman, Robert A Koeppe, Roderick Little, Hyonggin An, Larry Junck, Bruno Giordani, Carol Persad, Mary Heumann, Kris Wernett. Differentiation of Alzheimer's disease from dementia with Lewy bodies utilizing positron emission tomography with [18F]fluorodeoxyglucose and neuropsychological testing. Experimental neurology. vol 191 Suppl 1. 2005-03-29. PMID:15629765. |
pet studies revealed significantly lower local cerebral metabolic rates for glucose (lcmrglc) for visual cortex (brodmann areas 17, 18, and 19) in the dlb than the ad group, but no differences for other regions commonly affected in ad, including posterior cingulate, superior parietal lobe, lateral temporal lobe, and the prefrontal region. |
2005-03-29 |
2023-08-12 |
Not clear |
| Yuko Saito, Akiko Kawashima, Nyoka N Ruberu, Hideo Fujiwara, Shunichi Koyama, Motoji Sawabe, Tomio Arai, Hiroshi Nagura, Hiroshi Yamanouchi, Masato Hasegawa, Takeshi Iwatsubo, Shigeo Murayam. Accumulation of phosphorylated alpha-synuclein in aging human brain. Journal of neuropathology and experimental neurology. vol 62. issue 6. 2003-07-16. PMID:12834109. |
this novel pathology was abundantly present around lbs and also involved the limbic subcortical white matter, the cerebral cortical molecular layer, and the spongiform changes of the medial temporal lobe associated with cases of dementia with lbs (dlb). |
2003-07-16 |
2023-08-12 |
human |
| Yuko Saito, Akiko Kawashima, Nyoka N Ruberu, Hideo Fujiwara, Shunichi Koyama, Motoji Sawabe, Tomio Arai, Hiroshi Nagura, Hiroshi Yamanouchi, Masato Hasegawa, Takeshi Iwatsubo, Shigeo Murayam. Accumulation of phosphorylated alpha-synuclein in aging human brain. Journal of neuropathology and experimental neurology. vol 62. issue 6. 2003-07-16. PMID:12834109. |
the phosphorylated alpha-synuclein was limited to the temporal lobe in cases of parkinson disease, spread from the temporal lobe to the frontal lobe in cases of dlb transitional form and further spread to the parietal and occipital lobes in dlb neocortical form. |
2003-07-16 |
2023-08-12 |
human |
| Ian G McKeith, David J Burn, Clive G Ballard, Daniel Collerton, Evelyn Jaros, Chris M Morris, Andrew McLaren, Elaine K Perry, Robert Perry, Margaret A Piggott, John T O'Brie. Dementia with Lewy bodies. Seminars in clinical neuropsychiatry. vol 8. issue 1. 2003-04-17. PMID:12567332. |
relative preservation of medial temporal lobe volume on structural mri and the use of spect tracers for regional blood flow and the dopamine transporter are the most reliable current biomarkers for dlb. |
2003-04-17 |
2023-08-12 |
Not clear |
| Satoshi Minoshima, Norman L Foster, Eric C Petrie, Roger L Albin, Kirk A Frey, David E Kuh. Neuroimaging in dementia with Lewy bodies: metabolism, neurochemistry, and morphology. Journal of geriatric psychiatry and neurology. vol 15. issue 4. 2003-04-16. PMID:12489916. |
this article reviews current neuroimaging findings in dlb with particular attention to occipital hypometabolism, dopaminergic and cholinergic deficits, and medial temporal lobe atrophy as measured by positron emission tomography, single-photon emission computed tomography, and magnetic resonance imaging. |
2003-04-16 |
2023-08-12 |
Not clear |
| E J Burton, G Karas, S M Paling, R Barber, E D Williams, C G Ballard, I G McKeith, P Scheltens, F Barkhof, J T O'Brie. Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry. NeuroImage. vol 17. issue 2. 2002-11-25. PMID:12377138. |
relative preservation of the hippocampus and temporal lobe structures in dlb compared to ad has been reported in region-of-interest-based studies. |
2002-11-25 |
2023-08-12 |
human |
| E J Burton, G Karas, S M Paling, R Barber, E D Williams, C G Ballard, I G McKeith, P Scheltens, F Barkhof, J T O'Brie. Patterns of cerebral atrophy in dementia with Lewy bodies using voxel-based morphometry. NeuroImage. vol 17. issue 2. 2002-11-25. PMID:12377138. |
comparison of dementia groups showed preservation of the medial temporal lobe, hippocampus, and amygdala in dlb relative to ad. |
2002-11-25 |
2023-08-12 |
human |
| R Barber, I G McKeith, C Ballard, A Gholkar, J T O'Brie. A comparison of medial and lateral temporal lobe atrophy in dementia with Lewy bodies and Alzheimer's disease: magnetic resonance imaging volumetric study. Dementia and geriatric cognitive disorders. vol 12. issue 3. 2001-06-28. PMID:11244213. |
to compare medial and lateral temporal lobe atrophy on magnetic resonance imaging (mri) in dementia with lewy bodies (dlb) and alzheimer's disease (ad), and to examine the relationship between volumetric indices and cognitive and non-cognitive symptoms. |
2001-06-28 |
2023-08-12 |
Not clear |
| R A Armstrong, N J Cairns, P L Lanto. Beta-amyloid deposition in the temporal lobe of patients with dementia with Lewy bodies: comparison with non-demented cases and Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 11. issue 4. 2000-08-16. PMID:10867443. |
beta-amyloid (abeta) deposition in regions of the temporal lobe in patients with dementia with lewy bodies (dlb) was compared with elderly, non-demented (nd) cases and with alzheimer's disease (ad). |
2000-08-16 |
2023-08-12 |
Not clear |
| K Ishii, S Yamaji, H Kitagaki, T Imamura, N Hirono, E Mor. Regional cerebral blood flow difference between dementia with Lewy bodies and AD. Neurology. vol 53. issue 2. 1999-09-21. PMID:10430439. |
comparison with the statistical parametric mappings revealed that relative cerebral blood flow was lower in the occipital lobes and higher in the right medial temporal lobe in the dlb group than in the ad group. |
1999-09-21 |
2023-08-12 |
human |