Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Raffaella Giuffrida, Sebastiano Musumeci, Simona D'Antoni, Carmela Maria Bonaccorso, Anna Maria Giuffrida-Stella, Ben A Oostra, Maria Vincenza Catani. A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 39. 2006-02-21. PMID:16192381. |
initial in situ hybridization and western blotting experiments did not reveal differences in mrna levels and protein expression of ampa and nmda subunits and metabotropic glutamate subtype 5 (mglu5) receptors between control and fmr1 knock-out (ko) mice during postnatal development. |
2006-02-21 |
2023-08-12 |
mouse |
C M Spencer, O Alekseyenko, E Serysheva, L A Yuva-Paylor, R Paylo. Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome. Genes, brain, and behavior. vol 4. issue 7. 2006-01-23. PMID:16176388. |
in the mirrored chamber test, fmr1 ko mice showed greater aversion to the central mirrored chamber than wild-type (wt) littermates, suggesting increased anxiety-like responses to reflected images of mice. |
2006-01-23 |
2023-08-12 |
mouse |
C M Spencer, O Alekseyenko, E Serysheva, L A Yuva-Paylor, R Paylo. Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome. Genes, brain, and behavior. vol 4. issue 7. 2006-01-23. PMID:16176388. |
we further tested the influence of environmental familiarity on the social responses of fmr1 ko mice to unfamiliar partners. |
2006-01-23 |
2023-08-12 |
mouse |
Mei Qin, Julia Kang, Carolyn Beebe Smit. Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 24. 2003-01-14. PMID:12427968. |
a fragile x knockout (fmr1 ko) mouse has been described that has some of the characteristics of patients with fragile x syndrome, including immature dendritic spines and subtle behavioral deficits. |
2003-01-14 |
2023-08-12 |
mouse |
Mei Qin, Julia Kang, Carolyn Beebe Smit. Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 24. 2003-01-14. PMID:12427968. |
our finding of impaired performance of fmr1 ko mice on a passive avoidance task is suggestive of a deficit in learning and memory. |
2003-01-14 |
2023-08-12 |
mouse |