| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mosaad A Soltan, Ramdan S Shewita, Omaima A Matroud, Lamya Ahmed Alkeridis, Samy Sayed, Mustafa Shukry, Set A El-Shoboksh. Lignocellulose and probiotic supplementation in broiler chicken diet: effect on growth performance, digestive health, litter quality, and genes expression. Poultry science. vol 103. issue 6. 2024-04-23. PMID:38652957. |
dietary inclusion of lc and or b. subtilis supplementation significantly (p < 0.001) up-regulated hepatic growth-related genes (growth hormone receptor (ghr) and insulin growth factor1 (igf-1)) and antioxidant-related genes (superoxide dismutase 1 (sod1), glutathione peroxidase (gpx1) and uncoupling protein (ucp) and down-regulated (p < 0.001) splenic toll-like receptor 4 (tlrp) gene expression while had no significant effect on splenic interleukin 8 (il8) and tumor necrosis factor (tnf) with the best-obtained results with 1.0% followed by 0.5% lc with b. subtilis supplementation. |
2024-04-23 |
2024-04-26 |
chicken |
| Daiane Cattani, Paula Pierozan, Ariane Zamoner, Eva Brittebo, Oskar Karlsso. Long-Term Effects of Perinatal Exposure to a Glyphosate-Based Herbicide on Melatonin Levels and Oxidative Brain Damage in Adult Male Rats. Antioxidants (Basel, Switzerland). vol 12. issue 10. 2023-10-30. PMID:37891904. |
the perinatal exposure to gbh also induced long-term oxidative stress-related changes in the striatum demonstrated by increased lipid peroxidation (45%) and dna/rna oxidation (39%) together with increased protein levels of the antioxidant enzymes, superoxide dismutase (sod1, 24%), glutamate-cysteine ligase (gclc, 58%), and glutathione peroxidase 1 (gpx1, 31%). |
2023-10-30 |
2023-11-08 |
rat |
| Acácia Eduarda de Jesus Nascimento, Luciano Cardoso Santos, Bianca Reis Santos, Emilly Oliveira Santos, Maria Clara da Silva Galrão Cunha, Paola Pereira das Neves Snoeck, Mário Sérgio Lima de Lavor, Juneo Freitas Silv. Spatial and temporal expression profile of sex steroid receptors and antioxidant enzymes in the maternal-fetal interface of domestic cats. Theriogenology. vol 210. 2023-08-05. PMID:37542738. |
uterus and placenta samples from non-pregnant diestrus cats and cats in mid- and late pregnancy were used to analyze the protein and gene expression of the receptors for estrogen alpha (erα), progesterone (pr), and androgen (ar) and the antioxidant enzymes superoxide dismutase 1 (sod1), catalase, and glutathione peroxidase 1 (gpx1) by immunohistochemistry and qpcr. |
2023-08-05 |
2023-08-14 |
Not clear |
| Acácia Eduarda de Jesus Nascimento, Luciano Cardoso Santos, Bianca Reis Santos, Emilly Oliveira Santos, Maria Clara da Silva Galrão Cunha, Paola Pereira das Neves Snoeck, Mário Sérgio Lima de Lavor, Juneo Freitas Silv. Estrogen and progesterone receptors and antioxidant enzymes are expressed differently in the uterus of domestic cats during the estrous cycle. Theriogenology. vol 203. 2023-03-22. PMID:36947924. |
cats in proestrus/estrus (n = 6), diestrus, (n = 7), and anestrus (n = 6) were used to evaluate the uterine expression of estrogen alpha (erα), progesterone (pr), and androgen (ar) receptors and of the antioxidant enzymes superoxide dismutase 1 (sod1), catalase and glutathione peroxidase 1 (gpx1) by immunohistochemistry and qpcr. |
2023-03-22 |
2023-08-14 |
Not clear |
| Daniele Missio, Alexandro Fritzen, Camila Cupper Vieira, Juliana Germano Ferst, Mariani Farias Fiorenza, Leonardo Guedes de Andrade, Bento Martins de Menezes, Monique Tomazele Rovani, Bernardo Gazieira Gasperin, Paulo Bayard Dias Gonçalves, Rogério Ferreir. Increased β-hydroxybutyrate (BHBA) concentration affect follicular growth in cattle. Animal reproduction science. vol 243. 2022-07-11. PMID:35816934. |
in addition, the relative abundance of genes involved in the ovulatory cascade (adam 17, areg, ereg, ptgs2), steroidogenesis (cyp19a1, 3bhsd, star), cellular stress (sod1, cat, gpx1, hspa5, xbp1s, xbp1u, atf4, atf6), monocarboxylic acid transporters (slc16a1, slc16a7) and apoptosis (xiap) was similar between groups. |
2022-07-11 |
2023-08-14 |
cat |
| Michelle J Chandley, Attila Szebeni, Katalin Szebeni, Hui Wang-Heaton, Jacob Garst, Craig A Stockmeier, Nicole H Lewis, Gregory A Ordwa. Markers of elevated oxidative stress in oligodendrocytes captured from the brainstem and occipital cortex in major depressive disorder and suicide. Progress in neuro-psychopharmacology & biological psychiatry. 2022-04-22. PMID:35452747. |
relative telomere lengths and the gene expression of five antioxidant-related genes, sod1, sod2, gpx1, cat, and agps were measured in oligodendrocytes laser captured from two non-limbic brain areas: occipital cortical white matter and the brainstem locus coeruleus. |
2022-04-22 |
2023-08-13 |
cat |
| Paulina Wigner, Ewelina Synowiec, Piotr Czarny, Michal Bijak, Paweł Jóźwiak, Janusz Szemraj, Piotr Gruca, Mariusz Papp, Tomasz Śliwińsk. Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress. Journal of cellular and molecular medicine. vol 24. issue 10. 2021-09-07. PMID:32281745. |
this study investigates the effect of chronic administration of the serotonin-norepinephrine reuptake inhibitor, venlafaxine, on the expression and methylation status of sod1, sod2, gpx1, gpx4, cat, nos1 and nos2 in the brain and blood of rats exposed to a chronic mild stress (cms) model of depression. |
2021-09-07 |
2023-08-13 |
human |
| Paulina Wigner, Ewelina Synowiec, Piotr Czarny, Michal Bijak, Paweł Jóźwiak, Janusz Szemraj, Piotr Gruca, Mariusz Papp, Tomasz Śliwińsk. Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress. Journal of cellular and molecular medicine. vol 24. issue 10. 2021-09-07. PMID:32281745. |
cms increased the methylation of the gpx1 promoter in pbmcs, the second gpx4 promoter in midbrain and basal ganglia, and sod1 and sod2 in hippocampus. |
2021-09-07 |
2023-08-13 |
human |
| Małgorzata Mrowicka, Jerzy Mrowicki, Michał Mik, Łukasz Dziki, Adam Dziki, Ireneusz Majstere. Assessment of DNA damage profile and oxidative /antioxidative biomarker level in patients with inflammatory bowel disease. Polski przeglad chirurgiczny. vol 92. issue 5. 2021-06-17. PMID:33028732. |
<br><b>methods:</b> oxidative dna damage was measured by comet assay techniques; nitric oxide (no) and plasmatic lipid peroxidation (mda) as oxidative stress were valuated by colometric methods; superoxide dismutase (sod1), catalase (cat) and glutathione peroxidase (gpx1) as antioxidative defense were determined by spectrophotometric methods. |
2021-06-17 |
2023-08-13 |
human |
| Jasminka Giacometti, Tanja Grubić-Kezel. Olive Leaf Polyphenols Attenuate the Clinical Course of Experimental Autoimmune Encephalomyelitis and Provide Neuroprotection by Reducing Oxidative Stress, Regulating Microglia and SIRT1, and Preserving Myelin Integrity. Oxidative medicine and cellular longevity. vol 2020. 2021-05-13. PMID:32802267. |
in this study, we investigated the effect of olive leaf polyphenols on oxidative stress through oxidation marker level and activity (tbars, sod, and gpx) and their protein expression (sod1, sod2, and gpx1), as well as the protein expression of sirtuin 1 (sirt1) and microglia markers (iba-1, cd206, and inos) and myelin integrity (proteolipid protein expression) in the brain of rats with induced experimental autoimmune encephalomyelitis (eae) and subjected to olive leaf therapy. |
2021-05-13 |
2023-08-13 |
rat |
| Huijing Huang, Xuesong Liu, Dandan Chen, Yikang Lu, Jia Li, Fang Du, Chunyan Zhang, Liangjing L. Melatonin prevents endothelial dysfunction in SLE by activating the nuclear receptor retinoic acid-related orphan receptor-α. International immunopharmacology. vol 83. 2021-03-08. PMID:32172204. |
melatonin increased nitric oxide and antioxidant mrnas (sod1, gpx1, and cat) and downregulated reactive oxygen species (ros) level in huvecs, which may subsequently delay endothelial senescence and promote huvec proliferation and repair after injury. |
2021-03-08 |
2023-08-13 |
mouse |
| Ying Liao, Shiqin Peng, Lei He, Yu Wang, Yang Li, Danwei Ma, Yanan Wang, Liang Sun, Hong Zheng, Wenke Yang, Fengyan Dai, Jiayuan Zha. Methylmercury cytotoxicity and possible mechanisms in human trophoblastic HTR-8/SVneo cells. Ecotoxicology and environmental safety. vol 207. 2020-12-18. PMID:33254395. |
genes related to oxidative stress (hspa6, hspa1a, nrf2, sod1, ho-1, nqo1, osgin1, and gpx1), cell cycle (p21 and cdc25a), apoptosis (cycs and aifm2), and migration and invasion (cxcl8, cxcl3, clu, il24, col3a1, mapt, and itga7) were differentially expressed in the mehg-treated group, indicating mehg toxicity and mechanism of action. |
2020-12-18 |
2023-08-13 |
human |
| Sandra L. McFadden, Kevin K. Ohlemiller, Dalian Ding, Marlene Shero, Richard J. Salv. The Influence of Superoxide Dismutase and Glutathione Peroxidase Deficiencies on Noise-Induced Hearing Loss in Mice. Noise & health. vol 3. issue 11. 2019-11-20. PMID:12689448. |
in this chapter, we describe a series of experiments using mice with targeted deletions of sod1 or gpx1, the mouse genes that code for sod1 and gpx1, respectively, to study the cellular mechanisms underlying noise-induced hearing loss (nihl). |
2019-11-20 |
2023-08-12 |
mouse |
| A Štern, A Rotter, M Novak, M Filipič, B Žegur. Genotoxic effects of the cyanobacterial pentapeptide nodularin in HepG2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 124. 2019-04-18. PMID:30562542. |
moreover changes in the expression of selected genes from the p53 pathway, involved in the response to dna damage (p53, gadd45α, cdkn1a, mdm2), apoptosis (bax, bcl2) and oxidative stress (gpx1, gsr, gclc, cat, sod1) were determined using qpcr. |
2019-04-18 |
2023-08-13 |
human |
| Tsutomu Takahashi, Saki Suzuki, Suzuka Misawa, Jiro Akimoto, Yo Shinoda, Yasuyuki Fujiwar. Photodynamic therapy using talaporfin sodium induces heme oxygenase-1 expression in rat malignant meningioma KMY-J cells. The Journal of toxicological sciences. vol 43. issue 5. 2018-08-10. PMID:29743446. |
in this study, we investigated the gene expression of stress response proteins, including sod1, cat1, gstp1, gpx1, nqo1, and hmox1, in rat malignant meningioma kmy-j cells after treatment of ts-pdt. |
2018-08-10 |
2023-08-13 |
rat |
| Samson Jamesdaniel, Rita Rosati, Judy Westrick, Douglas M Rude. Chronic lead exposure induces cochlear oxidative stress and potentiates noise-induced hearing loss. Toxicology letters. vol 292. 2018-06-12. PMID:29746905. |
chronic lead exposure downregulated cochlear sod1, gpx1, and gstk1, which encode critical antioxidant enzymes, and upregulated apoe, hspa1a, ercc2, prnp, ccl5, and sqstm1, which are indicative of cellular apoptosis. |
2018-06-12 |
2023-08-13 |
mouse |
| Lindsay Joy Spielman, Deanna Lynn Gibson, Andis Klegeri. Incretin hormones regulate microglia oxidative stress, survival and expression of trophic factors. European journal of cell biology. vol 96. issue 3. 2018-03-02. PMID:28336086. |
we also show that incretins reduce oxidative stress in bv-2 microglia by inhibiting the accumulation of intracellular reactive oxygen species (ros) and release of nitric oxide (no), as well as by increasing the expression of the antioxidant glutathione peroxidase 1 (gpx1) and superoxide dismutase 1 (sod1). |
2018-03-02 |
2023-08-13 |
human |
| Jacek Kasznicki, Agnieszka Sliwinska, Marcin Kosmalski, Anna Merecz, Ireneusz Majsterek, Jozef Drzewosk. Genetic polymorphisms (Pro197Leu of Gpx1, +35A/C of SOD1, -262C/T of CAT), the level of antioxidant proteins (GPx1, SOD1, CAT) and the risk of distal symmetric polyneuropathy in Polish patients with type 2 diabetes mellitus. Advances in medical sciences. vol 61. issue 1. 2017-01-09. PMID:26674569. |
genetic polymorphisms (pro197leu of gpx1, +35a/c of sod1, -262c/t of cat), the level of antioxidant proteins (gpx1, sod1, cat) and the risk of distal symmetric polyneuropathy in polish patients with type 2 diabetes mellitus. |
2017-01-09 |
2023-08-13 |
cat |
| Goran Gajski, Ana-Marija Domijan, Bojana Žegura, Alja Štern, Marko Gerić, Ivana Novak Jovanović, Ivana Vrhovac, Josip Madunić, Davorka Breljak, Metka Filipič, Vera Garaj-Vrhova. Melittin induced cytogenetic damage, oxidative stress and changes in gene expression in human peripheral blood lymphocytes. Toxicon : official journal of the International Society on Toxinology. vol 110. 2016-10-19. PMID:26704293. |
mel also modulated the expression of selected genes involved in dna damage response (tp53, cdkn1a, gadd45α, mdm), oxidative stress (cat, sod1, gpx1, gsr and gclc) and apoptosis (bax, bcl-2, cas-3 and cas-7). |
2016-10-19 |
2023-08-13 |
human |
| Verónica Casañas-Sánchez, José A Pérez, David Quinto-Alemany, Mario Día. Sub-toxic Ethanol Exposure Modulates Gene Expression and Enzyme Activity of Antioxidant Systems to Provide Neuroprotection in Hippocampal HT22 Cells. Frontiers in physiology. vol 7. 2016-08-11. PMID:27512374. |
thus, we have observed that 0.1% ethanol exposure to ht22 cells, a murine hippocampal-derived cell line, increases the transcriptional expression of different genes belonging to the classical, glutathione/glutaredoxin and thioredoxin/peroxiredoxin antioxidant systems, these including sod1, sod2, gpx1, gclc, and txnrd1. |
2016-08-11 |
2023-08-13 |
Not clear |