| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura J Mahady, Sylvia E Perez, Michael Malek-Ahmadi, Elliott J Mufso. Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal-hippocampal connectome across stages of Alzheimer's disease. The Journal of comparative neurology. 2023-03-29. PMID:36989381. |
neurofibrillary tangles (nfts) contain abnormally phosphorylated tau proteins, which spread within components of the medial temporal lobe (mtl) memory circuit in alzheimer's disease (ad). |
2023-03-29 |
2023-08-14 |
human |
| Anup Das, Vinod Meno. Concurrent- and after-effects of medial temporal lobe stimulation on directed information flow to and from prefrontal and parietal cortices during memory formation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-03-24. PMID:36963847. |
electrical stimulation of the medial temporal lobe (mtl) has the potential to uncover causal circuit mechanisms underlying memory function. |
2023-03-24 |
2023-08-14 |
human |
| Sonja Chu, Cendri Hutcherson, Rutsuko Ito, Andy C H Le. Elucidating medial temporal and frontal lobe contributions to approach-avoidance conflict decision-making using functional MRI and the hierarchical drift diffusion model. Cerebral cortex (New York, N.Y. : 1991). 2023-03-21. PMID:36944537. |
the prefrontal cortex (pfc) has long been associated with arbitrating between approach and avoidance in the face of conflicting and uncertain motivational information, but recent work has also highlighted medial temporal lobe (mtl) involvement. |
2023-03-21 |
2023-08-14 |
human |
| Kaitlin M Stouffer, Claire Chen, Sue Kulason, Eileen Xu, Menno P Witter, Can Ceritoglu, Marilyn S Albert, Susumu Mori, Juan Troncoso, Daniel J Tward, Michael I Mille. Early amygdala and ERC atrophy linked to 3D reconstruction of rostral neurofibrillary tau tangle pathology in Alzheimer's disease. NeuroImage. Clinical. vol 38. 2023-03-19. PMID:36934675. |
previous research has emphasized the unique impact of alzheimer's disease (ad) pathology on the medial temporal lobe (mtl), a reflection that tau pathology is particularly striking in the entorhinal and transentorhinal cortex (erc, tec) early in the course of disease. |
2023-03-19 |
2023-08-14 |
Not clear |
| Jarkko Johansson, Anders Wåhlin, Anders Lundquist, Andreas M Brandmaier, Ulman Lindenberger, Lars Nyber. Model of brain maintenance reveals specific change-change association between medial-temporal lobe integrity and episodic memory. Aging brain. vol 2. 2023-03-13. PMID:36908884. |
critically, medial temporal lobe (mtl)/hippocampal change and episodic memory change were characterized by unique, residual variance beyond general factors of change in brain and cognition, and a reliable association between these two residualized variables was established ( |
2023-03-13 |
2023-08-14 |
human |
| Virginie Lambrecq, Irene Alonso, Dominique Hasboun, Vera Dinkelacker, Lila Davachi, Séverine Samson, Sophie Dupon. Memory functioning after hippocampal removal: Does side matter? Journal of neuropsychology. 2023-03-02. PMID:36861271. |
to address the memory functioning after medial temporal lobe (mtl) surgery for refractory epilepsy and relationships with the side of the hippocampal removal, 22 patients with pharmaco-resistant epilepsy who had undergone mtl resection (10 right/12 left) at the salpêtrière hospital were compared with 21 matched healthy controls. |
2023-03-02 |
2023-08-14 |
Not clear |
| Weizhen Xie, Marcus Cappiello, Michael A Yassa, Edward Ester, Kareem A Zaghloul, Weiwei Zhan. The entorhinal-DG/CA3 pathway in the medial temporal lobe retains visual working memory of a simple surface feature. eLife. vol 12. 2023-03-02. PMID:36861959. |
this computation has been referred to as pattern separation, which can be mediated by the entorhinal-dg/ca3 pathway of the medial temporal lobe (mtl) in service of long-term episodic memory. |
2023-03-02 |
2023-08-14 |
human |
| Weizhen Xie, Julio I Chapeton, Srijan Bhasin, Christopher Zawora, John H Wittig, Sara K Inati, Weiwei Zhang, Kareem A Zaghlou. The medial temporal lobe supports the quality of visual short-term memory representation. Nature human behaviour. 2023-03-02. PMID:36864132. |
here we use multiple experimental approaches to test the hypothesis that the quality of stm, such as its precision or fidelity, relies on the medial temporal lobe (mtl), a region commonly associated with the ability to distinguish similar information remembered in long-term memory. |
2023-03-02 |
2023-08-14 |
human |
| Xiaoming Zheng, Justin Cawood, Chris Hayre, Shaoyu Wan. Computer assisted diagnosis of Alzheimer's disease using statistical likelihood-ratio test. PloS one. vol 18. issue 2. 2023-02-17. PMID:36800393. |
the probability density functions of the likelihood ratio were constructed by using medial temporal lobe (mtl) volumes of patients with alzheimer's disease (ad) and normal controls (nc). |
2023-02-17 |
2023-08-14 |
Not clear |
| Marina Z Nakhla, Katherine J Bangen, Dawn M Schiehser, Scott Roesch, Zvinka Z Zlata. Greater subjective cognitive decline severity is associated with worse memory performance and lower entorhinal cerebral blood flow in healthy older adults. Journal of the International Neuropsychological Society : JINS. 2023-02-13. PMID:36781410. |
we investigated the relationship of scd severity with memory function and cerebral blood flow (cbf) in areas of the middle temporal lobe (mtl) in a cognitively normal and overall healthy sample of older adults. |
2023-02-13 |
2023-08-14 |
Not clear |
| Yue Cai, Jing Du, Anqi Li, Yalin Zhu, Linsen Xu, Kun Sun, Shaohua Ma, Tengfei Gu. Initial levels of β-amyloid and tau deposition have distinct effects on longitudinal tau accumulation in Alzheimer's disease. Alzheimer's research & therapy. vol 15. issue 1. 2023-02-08. PMID:36750884. |
to better assist with the design of future clinical trials for alzheimer's disease (ad) and aid in our understanding of the disease's symptomatology, it is essential to clarify what roles β-amyloid (aβ) plaques and tau tangles play in longitudinal tau accumulation inside and outside the medial temporal lobe (mtl) as well as how age, sex, apolipoprotein e (apoe) ε4 (apoe-ε4), and klotho-vs heterozygosity (kl-vs |
2023-02-08 |
2023-08-14 |
Not clear |
| Dan Yang, Jiangnan Li, Zhihong Ke, Ruomeng Qin, ChengLu Mao, Lili Huang, Yuting Mo, Zheqi Hu, Weiping Lv, Yanan Huang, Bing Zhang, Yun X. Subsystem mechanisms of default mode network underlying white matter hyperintensity-related cognitive impairment. Human brain mapping. 2023-02-01. PMID:36722495. |
compared with the wmh-nc group, the wmh-mci group displayed lower static fc within medial temporal lobe (mtl) and core subsystem, between core-mtl subsystem, as well as between core and dorsal medial prefrontal cortex subsystem. |
2023-02-01 |
2023-08-14 |
human |
| Viviane A Carvalho de Morais, Ana V de Oliveira-Pinto, Arthur F Mello Neto, Jaqueline S Freitas, Magnólia M da Silva, Claudia Kimie Suemoto, Renata P Leite, Lea T Grinberg, Wilson Jacob-Filho, Carlos Pasqualucci, Ricardo Nitrini, Paulo Caramelli, Roberto Len. Resilience of Neural Cellularity to the Influence of Low Educational Level. Brain sciences. vol 13. issue 1. 2023-01-21. PMID:36672086. |
one of the brain regions most impacted by education is the medial temporal lobe (mtl), a region that houses the hippocampus, which has an important role in learning processes and in consolidation of memories, and is also known to undergo neurogenesis in adulthood. |
2023-01-21 |
2023-08-14 |
Not clear |
| Ifrah Zawar, Jaideep Kapu. Does Alzheimer's disease with mesial temporal lobe epilepsy represent a distinct disease subtype? Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-01-17. PMID:36648207. |
we discuss shared pathological features including histopathology, an initial mesial temporal lobe (mtl) hyperexcitability followed by mtl dysfunction and involvement of same networks in memory (ad) and seizures (mtle). |
2023-01-17 |
2023-08-14 |
Not clear |
| Yipeng Zhang, Zahra M Aghajan, Matias Ison, Qiujing Lu, Hanlin Tang, Guldamla Kalender, Tonmoy Monsoor, Jie Zheng, Gabriel Kreiman, Vwani Roychowdhury, Itzhak Frie. Decoding of human identity by computer vision and neuronal vision. Scientific reports. vol 13. issue 1. 2023-01-12. PMID:36635322. |
this is the same challenge faced by the nervous system and partially addressed by the concept cells-neurons exhibiting selective firing in response to specific persons/places, described in the human medial temporal lobe (mtl) . |
2023-01-12 |
2023-08-14 |
human |
| Dengrong Jiang, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Emma Lucke, Abhay Moghekar, Jay J Pillai, Hanzhang L. MRI assessment of cerebral oxygen extraction fraction in the medial temporal lobe. NeuroImage. 2022-12-24. PMID:36565971. |
the medial temporal lobe (mtl) is a key area implicated in many brain diseases, such as alzheimer's disease. |
2022-12-24 |
2023-08-14 |
Not clear |
| Efthymia Maria Kapasouri, Diomidis C Ioannidis, Donnie Cameron, Vassilios S Vassiliou, Michael Hornberge. The Utility of Arterial Spin Labeling MRI in Medial Temporal Lobe as a Vascular Biomarker in Alzheimer's Disease Spectrum: A Systematic Review and Meta-Analysis. Diagnostics (Basel, Switzerland). vol 12. issue 12. 2022-12-23. PMID:36552974. |
we sought to systematically review and meta-analy the role of cerebral blood flow (cbf) in the medial temporal lobe (mtl) using arterial spin labeling magnetic resonance imaging (asl-mri) and compare this in patients with alzheimer's disease (ad), individuals with mild cognitive impairment (mci), and cognitively normal adults (cn). |
2022-12-23 |
2023-08-14 |
human |
| Helena M Gellersen, Alexandra N Trelle, Benjamin G Farrar, Gillian Coughlan, Saana M Korkki, Richard N Henson, Jon S Simon. Medial temporal lobe structure, mnemonic and perceptual discrimination in healthy older adults and those at risk for mild cognitive impairment. Neurobiology of aging. vol 122. 2022-12-14. PMID:36516558. |
cognitive tests sensitive to the integrity of the medial temporal lobe (mtl), such as mnemonic discrimination of perceptually similar stimuli, may be useful early markers of risk for cognitive decline in older populations. |
2022-12-14 |
2023-08-14 |
Not clear |
| Chloé Savignac, Sylvia Villeneuve, AmanPreet Badhwar, Karin Saltoun, Kimia Shafighi, Chris Zajner, Vaibhav Sharma, Sarah A Gagliano Taliun, Sali Farhan, Judes Poirier, Danilo Bzdo. APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer's disease and related dementia. PLoS biology. vol 20. issue 12. 2022-12-13. PMID:36512526. |
alzheimer's disease is marked by intracellular tau aggregates in the medial temporal lobe (mtl) and extracellular amyloid aggregates in the default network (dn). |
2022-12-13 |
2023-08-14 |
human |
| Hongkeun Ki. Neural correlates of paired associate recollection: A neuroimaging meta-analysis. Brain research. 2022-12-13. PMID:36513138. |
first, the hit > miss contrast mainly involved regions in the default mode network (dmn)/medial temporal lobe (mtl), likely reflecting a greater amount of retrieved information during the hit than miss trials. |
2022-12-13 |
2023-08-14 |
Not clear |