| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Göt. Regulation of neuronal cell death and differentiation by NGF and IAP family members. Journal of neural transmission. Supplementum. issue 60. 2001-04-12. PMID:11205144. |
nerve growth factor (ngf) and other neurotrophins were identified because of their trophic role for distinct populations of neurons in the peripheral nervous system. |
2001-04-12 |
2023-08-12 |
Not clear |
| S C Apfel, S Schwartz, B T Adornato, R Freeman, V Biton, M Rendell, A Vinik, M Giuliani, J C Stevens, R Barbano, P J Dyc. Efficacy and safety of recombinant human nerve growth factor in patients with diabetic polyneuropathy: A randomized controlled trial. rhNGF Clinical Investigator Group. JAMA. vol 284. issue 17. 2000-11-13. PMID:11056593. |
nerve growth factor is a neurotrophic factor that promotes the survival of small fiber sensory neurons and sympathetic neurons in the peripheral nervous system. |
2000-11-13 |
2023-08-12 |
human |
| G Bersani, A Iannitelli, M Fiore, F Angelucci, L Alo. Data and hypotheses on the role of nerve growth factor and other neurotrophins in psychiatric disorders. Medical hypotheses. vol 55. issue 3. 2000-11-08. PMID:10985909. |
nerve growth factor (ngf) was discovered and characterized for its role on the growth, differentiation and maintenance of specific neurons of the peripheral nervous system. |
2000-11-08 |
2023-08-12 |
Not clear |
| A Forgie, F Kuehnel, S Wyatt, A M Davie. In vivo survival requirement of a subset of nodose ganglion neurons for nerve growth factor. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712647. |
the sensory neurons of the nodose ganglion are the classic example of a population of peripheral nervous system neurons that do not require nerve growth factor (ngf) for survival during development but are dependent on other neurotrophins. |
2000-05-25 |
2023-08-12 |
mouse |
| R H Baloh, H Enomoto, E M Johnson, J Milbrand. The GDNF family ligands and receptors - implications for neural development. Current opinion in neurobiology. vol 10. issue 1. 2000-03-22. PMID:10679429. |
the results of such analyses reveal numerous similarities and potential overlaps in the way the gdnf and the nerve growth factor (ngf) families regulate development of the peripheral nervous system. |
2000-03-22 |
2023-08-12 |
mouse |
| C A Ras. Biological actions of nerve growth factor in the peripheral nervous system. European neurology. vol 41 Suppl 1. 1999-04-28. PMID:10023124. |
biological actions of nerve growth factor in the peripheral nervous system. |
1999-04-28 |
2023-08-12 |
human |
| L J Klesse, L F Parad. p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 24. 1999-02-25. PMID:9852579. |
nerve growth factor (ngf) is a required differentiation and survival factor for sympathetic and a majority of neural crest-derived sensory neurons in the developing vertebrate peripheral nervous system. |
1999-02-25 |
2023-08-12 |
mouse |
| V Lessman. Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. General pharmacology. vol 31. issue 5. 1998-12-23. PMID:9809461. |
the protein family of the neurotrophins, consisting of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and neurotrophin-3, -4/5, and -6 (nt-3; nt-4/5; nt-6) is well known to enhance the survival and to stabilize the phenotype of different populations of neurons in the central and the peripheral nervous system. |
1998-12-23 |
2023-08-12 |
Not clear |
| J M Frade, Y A Bard. Nerve growth factor: two receptors, multiple functions. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 20. issue 2. 1998-07-09. PMID:9631659. |
nerve growth factor (ngf) was characterized over 4 decades ago, and like the other neurotrophins subsequently discovered, it is best known for its trophic role, including the prevention of programmed cell death in specific populations of neurones in the peripheral nervous system. |
1998-07-09 |
2023-08-12 |
Not clear |
| A D Toews, G J Harry, K B Lowrey, D L Morgan, R C Sill. Carbon disulfide neurotoxicity in rats: IV. Increased mRNA expression of low-affinity nerve growth factor receptor--a sensitive and early indicator of PNS damage. Neurotoxicology. vol 19. issue 1. 1998-04-21. PMID:9498227. |
expression of the low-affinity nerve growth factor receptor (ngf-r) in the peripheral nervous system is regulated by schwann cell-axonal contact. |
1998-04-21 |
2023-08-12 |
rat |
| A M Fagan, M Garber, M Barbacid, I Silos-Santiago, D M Holtzma. A role for TrkA during maturation of striatal and basal forebrain cholinergic neurons in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 20. 1997-10-23. PMID:9315886. |
nerve growth factor (ngf), acting via the trka receptor, has been shown to regulate the survival and maturation of specific neurons of the peripheral nervous system. |
1997-10-23 |
2023-08-12 |
mouse |
| B C Roger. Development of recombinant human nerve growth factor (rhNGF) as a treatment for peripheral neuropathic disease. Neurotoxicology. vol 17. issue 3-4. 1997-06-23. PMID:9086510. |
since its discovery over thirty years ago, the role played by nerve growth factor (ngf) in the development and maintenance of sympathetic and sensory neurons of the peripheral nervous system has been well established and extensively studied. |
1997-06-23 |
2023-08-12 |
human |
| A Bäckström, S Söderström, A Kylberg, T Ebenda. Molecular cloning of the chicken trkA and its expression in early peripheral ganglia. Journal of neuroscience research. vol 46. issue 1. 1997-05-13. PMID:8892107. |
their cognate ligands nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin-4 (nt-4), and neurotrophin-3 (nt-3) act as survival and trophic factors for neurons in the peripheral nervous system (pns). |
1997-05-13 |
2023-08-12 |
human |
| Z Pan, R Perez-Pol. Increased uptake of L-cysteine and L-cystine by nerve growth factor in rat pheochromocytoma cells. Brain research. vol 740. issue 1-2. 1997-03-19. PMID:8973794. |
nerve growth factor is a neurotrophic factor which promotes cell survival and differentiation in the central and peripheral nervous system. |
1997-03-19 |
2023-08-12 |
rat |
| M Yamamoto, G Sobue, K Yamamoto, S Terao, T Mitsum. Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues. Neurochemical research. vol 21. issue 8. 1997-02-18. PMID:8895847. |
the steady-state mrna levels of the four neurotrophic factors of nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3) and glial cell line-derived neurotrophic factor (gdnf) and their receptors (p75ngfr, trka, trkb and trkc) in the adult human peripheral nervous system (pns) as well as nonneural tissues were examined using quantitative reverse transcription-polymerase chain reaction (rt-pcr). |
1997-02-18 |
2023-08-12 |
human |
| R Hellweg, C Baethge, H D Hartung, M K Brückner, T Arend. NGF level in the rat sciatic nerve is decreased after long-term consumption of ethanol. Neuroreport. vol 7. issue 3. 1996-11-05. PMID:8733743. |
long-term effects of ethanol consumption on endogenous nerve growth factor (ngf) level were investigated in ngf-producing target organs and tissues of the peripheral nervous system. |
1996-11-05 |
2023-08-12 |
rat |
| J N Kew, D W Smith, M V Sofronie. Nerve growth factor withdrawal induces the apoptotic death of developing septal cholinergic neurons in vitro: protection by cyclic AMP analogue and high potassium. Neuroscience. vol 70. issue 2. 1996-10-22. PMID:8848143. |
nerve growth factor regulates the developmental programmed cell death of certain neurons in the peripheral nervous system. |
1996-10-22 |
2023-08-12 |
Not clear |
| S C Apfel, D E Wright, A M Wiideman, C Dormia, W D Snider, J A Kessle. Nerve growth factor regulates the expression of brain-derived neurotrophic factor mRNA in the peripheral nervous system. Molecular and cellular neurosciences. vol 7. issue 2. 1996-09-20. PMID:8731481. |
nerve growth factor regulates the expression of brain-derived neurotrophic factor mrna in the peripheral nervous system. |
1996-09-20 |
2023-08-12 |
Not clear |
| G Conti, P L Baron, E Scarpini, C Vedeler, A Rostami, D Pleasure, G Scarlat. Low-affinity nerve growth factor receptor expression in sciatic nerve during P2-peptide induced experimental allergic neuritis. Neuroscience letters. vol 199. issue 2. 1996-03-20. PMID:8584242. |
northern blot, immunocytochemistry, and single nerve fiber immunostaining were used to determine the expression of low-affinity nerve growth factor (ngf) receptor (p75ngfr) in the peripheral nervous system of lewis rats during the course of experimental allergic neuritis (ean) induced with 100 micrograms of 'sp26' synthetic peptide, corresponding to residues 53-78 of bovine p2 myelin protein. |
1996-03-20 |
2023-08-12 |
rat |
| P Burnham, J M Conner, S Varo. Colocalization of NGF and TSH-like immunoreactivity in cultures of adult rat anterior pituitary cells. Journal of neuroscience research. vol 41. issue 1. 1995-10-17. PMID:7674379. |
nerve growth factor (ngf) has been well-characterized with respect to its role as a trophic agent for various peripheral nervous system (pns) and central nervous system (cns) neuronal populations. |
1995-10-17 |
2023-08-12 |
rat |