| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Rodriguez-Tébar, H Rohre. Retinoic acid induces NGF-dependent survival response and high-affinity NGF receptors in immature chick sympathetic neurons. Development (Cambridge, England). vol 112. issue 3. 1991-11-25. PMID:1657566. |
these findings suggest that the induction of high-affinity ngf receptors may be sufficient to activate the survival response in sympathetic neurons and imply an important role for ra during neuron differentiation in the peripheral nervous system. |
1991-11-25 |
2023-08-11 |
chicken |
| M Yaar, K Grossman, M Eller, B A Gilchres. Evidence for nerve growth factor-mediated paracrine effects in human epidermis. The Journal of cell biology. vol 115. issue 3. 1991-11-21. PMID:1655813. |
nerve growth factor (ngf) is critical to the development and maintenance of the peripheral nervous system, but its possible roles in other organ systems are less well characterized. |
1991-11-21 |
2023-08-11 |
human |
| A Acheson, P A Barker, R F Alderson, F D Miller, R A Murph. Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF. Neuron. vol 7. issue 2. 1991-09-20. PMID:1873030. |
these results suggest that molecules with bdnf-like activity may be produced by cells in the peripheral nervous system and that the bdnf-like activity in fibroblasts and schwann cells is derived from molecules immunologically related to ngf. |
1991-09-20 |
2023-08-11 |
rat |
| G Raivich, R Hellweg, G W Kreutzber. NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration. Neuron. vol 7. issue 1. 1991-08-22. PMID:1648938. |
in view of the massive ngf synthesis occurring in the injured nerve, these results suggest that, while sensory and sympathetic neurons are the primary targets of ngf in the normal peripheral nervous system, the denervated schwann cells may become its primary target in the aftermath of nerve injury. |
1991-08-22 |
2023-08-11 |
rat |
| L Callegaro, S D Skaper, G Vantini, D Benvegnù, A Di Martino, N Schiavo, C Triban, C Minozzi, A Leo. Purification and characterization of Fab fragments from anti-mouse NGF polyclonal antibodies. Journal of molecular recognition : JMR. vol 3. issue 5-6. 1991-07-24. PMID:2096885. |
a functional role for nerve growth factor (ngf) in the peripheral nervous system is well-documented, but a similar case for ngf in the central nervous system remains to be established. |
1991-07-24 |
2023-08-11 |
rat |
| S R Salton, D J Fischberg, K W Don. Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells. Molecular and cellular biology. vol 11. issue 5. 1991-05-21. PMID:2017159. |
nerve growth factor (ngf) plays a critical role in the development and survival of neurons in the peripheral nervous system. |
1991-05-21 |
2023-08-11 |
rat |
| M A Watson, J Milbrand. Expression of the nerve growth factor-regulated NGFI-A and NGFI-B genes in the developing rat. Development (Cambridge, England). vol 110. issue 1. 1991-05-03. PMID:2081458. |
results obtained with this assay demonstrated that expression of both ngfi-a and ngfi-b is modulated in the peripheral nervous system during postnatal maturation, but not in a pattern concordant with previously characterized ngf receptor expression. |
1991-05-03 |
2023-08-11 |
rat |
| S Söderström, F Hallböök, C F Ibáñez, H Persson, T Ebenda. Recombinant human beta-nerve growth factor (NGF): biological activity and properties in an enzyme immunoassay. Journal of neuroscience research. vol 27. issue 4. 1991-04-26. PMID:2079723. |
nerve growth factor (ngf) supports sympathetic and sensory neurons in the peripheral nervous system and also functions in the development and maintenance of cholinergic neurons in the basal forebrain. |
1991-04-26 |
2023-08-11 |
mouse |
| S Furukawa, Y Furukaw. Nerve growth factor synthesis and its regulatory mechanisms: an approach to therapeutic induction of nerve growth factor synthesis. Cerebrovascular and brain metabolism reviews. vol 2. issue 4. 1991-03-01. PMID:1980419. |
evidence that ngf has a potent protective activity on neuronal degeneration both in the central nervous system (cns) and peripheral nervous system (pns) is accumulating. |
1991-03-01 |
2023-08-11 |
rat |
| S Furukawa, I Shinoda, Y Furukaw. [Regulatory mechanisms of nerve growth factor synthesis in vitro]. Human cell. vol 2. issue 2. 1991-02-14. PMID:2486602. |
astroglial cells and various types of non-neuronal cells in the peripheral nervous system, such as epithelial, schwann and fibroblast cells synthesize and secrete nerve growth factor (ngf) in culture. |
1991-02-14 |
2023-08-11 |
mouse |
| D M Katz, M Erb, R Lillis, K Nee. Trophic regulation of nodose ganglion cell development: evidence for an expanded role of nerve growth factor during embryogenesis in the rat. Experimental neurology. vol 110. issue 1. 1990-11-21. PMID:2170162. |
these findings indicate that ngf may be important in regulating nodose development during early gangliogenesis in mammals and suggest that ngf plays a more widespread role in peripheral nervous system ontogeny than previously recognized. |
1990-11-21 |
2023-08-11 |
rat |
| C E Bandtlow, M Meyer, D Lindholm, M Spranger, R Heumann, H Thoene. Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: possible relationship to the regulation of nerve growth factor synthesis. The Journal of cell biology. vol 111. issue 4. 1990-11-02. PMID:2211833. |
these data indicate that il 1 beta, among other factors, might also play a regulatory role in the synthesis of ngf in the cns, as has been demonstrated in the peripheral nervous system (lindholm, d., r. heumann, m. meyer, and h. thoenen. |
1990-11-02 |
2023-08-11 |
rat |
| G R Jackson, L Apffel, K Werrbach-Perez, J R Perez-Pol. Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance. Journal of neuroscience research. vol 25. issue 3. 1990-05-24. PMID:2325161. |
the nerve growth factor protein (ngf) regulates neuronal cell death during the development of embryonic sensory and sympathetic neurons in the peripheral nervous system (pns). |
1990-05-24 |
2023-08-11 |
rat |
| B Lu, C R Buck, C F Dreyfus, I B Blac. Expression of NGF and NGF receptor mRNAs in the developing brain: evidence for local delivery and action of NGF. Experimental neurology. vol 104. issue 3. 1989-07-07. PMID:2542076. |
nerve growth factor (ngf) is a well-documented target-derived trophic factor in the peripheral nervous system. |
1989-07-07 |
2023-08-11 |
Not clear |
| R M Lindsa. Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 7. 1989-06-29. PMID:3249232. |
largely on the basis of studies with nerve growth factor (ngf), it is now widely accepted that development of the peripheral nervous system of vertebrates is dependent in part on the interaction of immature sensory and autonomic neurons with specific survival factors that are derived from peripheral target fields. |
1989-06-29 |
2023-08-11 |
rat |
| J E Springe. Nerve growth factor receptors in the central nervous system. Experimental neurology. vol 102. issue 3. 1989-01-26. PMID:2848710. |
nerve growth factor (ngf) is well known to be involved in the development, survival, and maintenance of sympathetic and neural crest-derived sensory neurons in the peripheral nervous system. |
1989-01-26 |
2023-08-11 |
Not clear |
| G Weskamp, U Otte. An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues. Journal of neurochemistry. vol 48. issue 6. 1987-06-25. PMID:3572400. |
the sensitivity of this assay (0.1 pg/well) permits the quantification of endogenous immunoreactive ngf in the peripheral nervous system and the cns. |
1987-06-25 |
2023-08-11 |
Not clear |
| K A Crutche. The role of growth factors in neuronal development and plasticity. CRC critical reviews in clinical neurobiology. vol 2. issue 3. 1986-12-23. PMID:3536312. |
however, one model of collateral sprouting of axons from the peripheral nervous system (pns) into the central nervous system (cns) appears to involve the action of a growth factor with properties similar to ngf. |
1986-12-23 |
2023-08-11 |
Not clear |
| M Taniuchi, J B Schweitzer, E M Johnso. Nerve growth factor receptor molecules in rat brain. Proceedings of the National Academy of Sciences of the United States of America. vol 83. issue 6. 1986-04-24. PMID:2419914. |
these findings demonstrate the presence in brain of ngf receptor molecules indistinguishable from those of the peripheral nervous system. |
1986-04-24 |
2023-08-11 |
rat |
| D L Shelton, L F Reichard. Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs. Proceedings of the National Academy of Sciences of the United States of America. vol 81. issue 24. 1985-02-21. PMID:6595669. |
ngf mrna was also found in other areas, including elements of the adult peripheral nervous system--the sciatic nerve and the sympathetic and sensory ganglia. |
1985-02-21 |
2023-08-12 |
Not clear |