| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Ng, A Rüsch, L L Amma, K Nordström, L C Erway, B Vennström, D Forres. Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene. Human molecular genetics. vol 10. issue 23. 2002-01-31. PMID:11726557. |
these findings reveal a novel modifying function for a thra allele and suggest that increased expression of tr alpha 1 may substitute for the absence of tr beta. |
2002-01-31 |
2023-08-12 |
mouse |
| L Ng, A Rüsch, L L Amma, K Nordström, L C Erway, B Vennström, D Forres. Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene. Human molecular genetics. vol 10. issue 23. 2002-01-31. PMID:11726557. |
the thra(tm2) mutation deletes tr alpha 2 and concomitantly causes overexpression of tr alpha 1 as a consequence of the exon structure of the gene. |
2002-01-31 |
2023-08-12 |
mouse |
| Y S Koh, D D Moor. Linkage of the nuclear hormone receptor genes NR1D2, THRB, and RARB: evidence for an ancient, large-scale duplication. Genomics. vol 57. issue 2. 1999-05-06. PMID:10198169. |
the thra gene encoding thyroid hormone receptor alpha shares an unusual partial overlap with the nr1d1 gene encoding the orphan receptor rev-erbaalpha. |
1999-05-06 |
2023-08-12 |
human |
| V Laudet, J M Vanacker, G Adelmant, A Begue, D Steheli. Characterization of a functional promoter for the human thyroid hormone receptor alpha (c-erbA-1) gene. Oncogene. vol 8. issue 4. 1993-04-20. PMID:8455948. |
the thyroid hormone receptor alpha (thra or c-erba-1) gene belongs to a family of genes that encode nuclear receptors for various hydrophobic ligands such as steroids, retinoic acid and thyroid hormones. |
1993-04-20 |
2023-08-12 |
human |
| V Laudet, A Begue, C Henry-Duthoit, A Joubel, P Martin, D Stehelin, S Saul. Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene. Nucleic acids research. vol 19. issue 5. 1991-05-28. PMID:1850510. |
the thyroid hormone receptor alpha (thra or c-erba-1) gene belongs to a family of genes which encode nuclear receptors for various hydrophobic ligands such as steroids, vitamin d, retinoic acid and thyroid hormones. |
1991-05-28 |
2023-08-11 |
human |