| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aaron B Ilan, Michael E Smith, Alan Gevin. Effects of marijuana on neurophysiological signals of working and episodic memory. Psychopharmacology. vol 176. issue 2. 2005-02-17. PMID:15502936. |
the primary psychoactive constituent of marijuana, delta9-thc, activates cannabinoid receptors, which are especially abundant in the frontal cortex and hippocampus. |
2005-02-17 |
2023-08-12 |
Not clear |
| Matthew J McFarland, Eric L Barke. Anandamide transport. Pharmacology & therapeutics. vol 104. issue 2. 2005-02-17. PMID:15518883. |
n-arachidonylethanolamine (anandamide) is an endogenous agonist of the cannabinoid cb1 and cb2 receptors and displays many of the same receptor-mediated physiological effects as delta9-tetrahydrocannabinol (delta9-thc), the active component of marijuana. |
2005-02-17 |
2023-08-12 |
Not clear |
| P-W Zhang, H Ishiguro, T Ohtsuki, J Hess, F Carillo, D Walther, E S Onaivi, T Arinami, G R Uh. Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Molecular psychiatry. vol 9. issue 10. 2005-02-15. PMID:15289816. |
the cb1/cnr1 receptor is the major brain site at which cannabinoid marijuana constituents are psychoactive as well as the principal brain receptor for endogenous anandamide ligands. |
2005-02-15 |
2023-08-12 |
mouse |
| Sharon Woo. Evidence for using cannabis and cannabinoids to manage pain. Nursing times. vol 100. issue 49. 2005-02-10. PMID:15630971. |
evidence for using cannabis and cannabinoids to manage pain. |
2005-02-10 |
2023-08-12 |
Not clear |
| C M Brady, R DasGupta, C Dalton, O J Wiseman, K J Berkley, C J Fowle. An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England). vol 10. issue 4. 2005-02-08. PMID:15327041. |
anecdotal reports suggest that cannabis may alleviate luts, and cannabinoid receptors in the bladder and nervous system are potential pharmacological targets. |
2005-02-08 |
2023-08-12 |
Not clear |
| Daniel S McQueen, Susan M Bond, Paula J W Smith, Kia Balali-Mood, Darren Smar. Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats. European journal of pharmacology. vol 491. issue 2-3. 2005-02-07. PMID:15140635. |
the results of vasorespiratory studies in rats anaesthetised with pentobarbital show that (+/-) cannabidiol, a cannabinoid that lacks psychotropic actions and is inactive at cannabinoid (cb) receptors, does not affect respiration or blood pressure when injected (1-2000 microg; 3.2-6360 nmol i.a.). |
2005-02-07 |
2023-08-12 |
human |
| Eric S Lavins, Bethany D Lavins, Amanda J Jenkin. Cannabis (marijuana) contamination of United States and foreign paper currency. Journal of analytical toxicology. vol 28. issue 6. 2005-02-04. PMID:15516293. |
as is the case with cocaine, differentiating "background levels" of the various cannabinoid constituents of cannabis sativa l., namely, delta(9)-tetrahydrocannabinol (thc), cannabinol (cbn), and cannabidiol (cbd) contaminating currency found in the general circulation from currency associated with illegal drug activity is imperative if a legal nexus is to be established with the latter. |
2005-02-04 |
2023-08-12 |
Not clear |
| Eric S Lavins, Bethany D Lavins, Amanda J Jenkin. Cannabis (marijuana) contamination of United States and foreign paper currency. Journal of analytical toxicology. vol 28. issue 6. 2005-02-04. PMID:15516293. |
this study demonstrated that marijuana (cannabinoids) may contaminate both paper and plastic currency. |
2005-02-04 |
2023-08-12 |
Not clear |
| F Markus Leweke, Christoph W Gerth, Joachim Klosterkötte. Cannabis-associated psychosis: current status of research. CNS drugs. vol 18. issue 13. 2005-02-04. PMID:15521792. |
from a clinical perspective, toxic or transient psychotic reactions to the administration of herbal cannabis preparations or specific cannabinoid compounds have to be differentiated from longer-lasting, persistent schizophrenia-like disorders associated with the use of cannabis/cannabinoids. |
2005-02-04 |
2023-08-12 |
Not clear |
| F Markus Leweke, Christoph W Gerth, Joachim Klosterkötte. Cannabis-associated psychosis: current status of research. CNS drugs. vol 18. issue 13. 2005-02-04. PMID:15521792. |
interestingly, the recently suggested role of the endogenous cannabinoid system in schizophrenia not related to previous cannabinoid consumption introduces an additional perspective on the mechanism underlying cannabis-associated schizophrenia-like disorders, as well as on the effects of cannabis consumption in schizophrenia. |
2005-02-04 |
2023-08-12 |
Not clear |
| Wayne Hall, MacDonald Christie, David Curro. Cannabinoids and cancer: causation, remediation, and palliation. The Lancet. Oncology. vol 6. issue 1. 2005-02-03. PMID:15629274. |
these very different uses of cannabinoids are in danger of being confused in public debate, especially in the usa where some advocates for the medical use of cannabinoids have argued for smoked cannabis rather than pharmaceutical cannabinoids. |
2005-02-03 |
2023-08-12 |
Not clear |
| Linda A Parker, Page Burton, Robert E Sorge, Christine Yakiwchuk, Raphael Mechoula. Effect of low doses of delta9-tetrahydrocannabinol and cannabidiol on the extinction of cocaine-induced and amphetamine-induced conditioned place preference learning in rats. Psychopharmacology. vol 175. issue 3. 2005-02-02. PMID:15138755. |
using the place-preference conditioning paradigm, we evaluated the potential of the two most prominent cannabinoids found in marijuana, the psychoactive component delta9-tetrahydrocannabinol (delta9-thc) and the nonpsychoactive component cannabidiol (cbd), to potentiate extinction of a cocaine-induced and an amphetamine-induced conditioned place preference in rats. |
2005-02-02 |
2023-08-12 |
rat |
| Jorge Manzanares, Leyre Urigüen, Gabriel Rubio, Tomás Palom. Role of endocannabinoid system in mental diseases. Neurotoxicity research. vol 6. issue 3. 2005-01-31. PMID:15325960. |
in the last decade, a large number of studies using delta9-tetrahydrocannabinol (thc), the main active principle derivative of the marijuana plant, or cannabinoid synthetic derivatives have substantially contributed to advance the understanding of the pharmacology and neurobiological mechanisms produced by cannabinoid receptor activation. |
2005-01-31 |
2023-08-12 |
Not clear |
| Jorge Manzanares, Leyre Urigüen, Gabriel Rubio, Tomás Palom. Role of endocannabinoid system in mental diseases. Neurotoxicity research. vol 6. issue 3. 2005-01-31. PMID:15325960. |
following the historical reports of the use of cannabis for medicinal purposes, recent research has highlighted the potential of cannabinoids to treat a wide variety of clinical disorders. |
2005-01-31 |
2023-08-12 |
Not clear |
| Jorge Manzanares, Leyre Urigüen, Gabriel Rubio, Tomás Palom. Role of endocannabinoid system in mental diseases. Neurotoxicity research. vol 6. issue 3. 2005-01-31. PMID:15325960. |
considering that cannabis or cannabinoid pharmaceutical preparations may no longer be exclusively recreational drugs but may also present potential therapeutic uses, it has become of great interest to analyze the neurobiological and behavioral consequences of their administration. |
2005-01-31 |
2023-08-12 |
Not clear |
| Young Hae Choi, Arno Hazekamp, Anja M G Peltenburg-Looman, Michel Frédérich, Cornelis Erkelens, Alfons W M Lefeber, Robert Verpoort. NMR assignments of the major cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa. Phytochemical analysis : PCA. vol 15. issue 6. 2005-01-31. PMID:15595449. |
nmr assignments of the major cannabinoids and cannabiflavonoids isolated from flowers of cannabis sativa. |
2005-01-31 |
2023-08-12 |
Not clear |
| Angelo A Izz. Cannabinoids and intestinal motility: welcome to CB2 receptors. British journal of pharmacology. vol 142. issue 8. 2005-01-26. PMID:15277313. |
delta(9)-tetrahydrocannabinol (the active ingredient of marijuana), as well as endogenous and synthetic cannabinoids, exert many biological functions by activating two types of cannabinoid receptors, cb(1) receptors (expressed by central and peripheral neurons) and cb(2) receptors (that occur mainly in immune cells). |
2005-01-26 |
2023-08-12 |
rat |
| Javier Fernández-Ruiz, María Gómez, Mariluz Hernández, Rosario de Miguel, José A Ramo. Cannabinoids and gene expression during brain development. Neurotoxicity research. vol 6. issue 5. 2005-01-26. PMID:15545023. |
it is consumed even by women during pregnancy and lactation, which result in a variety of disturbances in the development of their offspring, because, like other habit-forming drugs, cannabinoids, the psychoactive ingredients of marijuana, can cross the placental barrier and be secreted in the maternal milk. |
2005-01-26 |
2023-08-12 |
Not clear |
| Arno Hazekamp, Young Hae Choi, Robert Verpoort. Quantitative analysis of cannabinoids from Cannabis sativa using 1H-NMR. Chemical & pharmaceutical bulletin. vol 52. issue 6. 2005-01-07. PMID:15187394. |
quantitative analysis of cannabinoids from cannabis sativa using 1h-nmr. |
2005-01-07 |
2023-08-12 |
Not clear |
| Arno Hazekamp, Young Hae Choi, Robert Verpoort. Quantitative analysis of cannabinoids from Cannabis sativa using 1H-NMR. Chemical & pharmaceutical bulletin. vol 52. issue 6. 2005-01-07. PMID:15187394. |
a (1)h-nmr method has been developed for the quantitative analysis of pure cannabinoids and for cannabinoids present in cannabis sativa plant material without any chromatographic purification. |
2005-01-07 |
2023-08-12 |
Not clear |