| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A H Lichtman, J L Poklis, A Poklis, D M Wilson, B R Marti. The pharmacological activity of inhalation exposure to marijuana smoke in mice. Drug and alcohol dependence. vol 63. issue 2. 2001-08-30. PMID:11376914. |
the aim of the present study was to evaluate the impact of inhaling marijuana, or ethanol-extracted placebo smoke in the mouse model of cannabinoid activity by assessing inhibition of spontaneous activity, antinociception, catalepsy, and body temperature. |
2001-08-30 |
2023-08-12 |
mouse |
| Y H Chang, S T Lee, W W Li. Effects of cannabinoids on LPS-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. Journal of cellular biochemistry. vol 81. issue 4. 2001-06-28. PMID:11329626. |
delta(9)-tetrahydrocannabinol (delta(9)-thc) is the major psychoactive component of marijuana and elicits pharmacological actions via cannabinoid receptors. |
2001-06-28 |
2023-08-12 |
Not clear |
| V Di Marzo, S K Goparaju, L Wang, J Liu, S Bátkai, Z Járai, F Fezza, G I Miura, R D Palmiter, T Sugiura, G Kuno. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature. vol 410. issue 6830. 2001-06-07. PMID:11298451. |
however, alternative orexigenic pathways maintain food intake in mice deficient in neuropeptide y. cb1 cannabinoid receptors and the endocannabinoids anandamide and 2-arachidonoyl glycerol are present in the hypothalamus, and marijuana and anandamide stimulate food intake. |
2001-06-07 |
2023-08-12 |
mouse |
| M Guzmán, C Sánchez, I Galve-Roper. Control of the cell survival/death decision by cannabinoids. Journal of molecular medicine (Berlin, Germany). vol 78. issue 11. 2001-05-31. PMID:11269508. |
cannabinoids, the active components of cannabis sativa (marijuana), and their derivatives produce a wide spectrum of central and peripheral effects, some of which may have clinical application. |
2001-05-31 |
2023-08-12 |
Not clear |
| P D Skosnik, L Spatz-Glenn, S Par. Cannabis use is associated with schizotypy and attentional disinhibition. Schizophrenia research. vol 48. issue 1. 2001-05-31. PMID:11278156. |
these results suggest that cannabis use can mimic attentional deficits seen in acute schizophrenia and is associated with schizotypal personality, thus setting the stage for a possible cannabinoid model of sz. |
2001-05-31 |
2023-08-12 |
Not clear |
| P Robso. Therapeutic aspects of cannabis and cannabinoids. The British journal of psychiatry : the journal of mental science. vol 178. 2001-05-17. PMID:11157423. |
therapeutic aspects of cannabis and cannabinoids. |
2001-05-17 |
2023-08-12 |
Not clear |
| T Yamaguchi, Y Shoyama, S Watanabe, T Yamamot. Behavioral suppression induced by cannabinoids is due to activation of the arachidonic acid cascade in rats. Brain research. vol 889. issue 1-2. 2001-05-17. PMID:11166698. |
tetrahydrocannabinol (thc) is the principle psychoactive ingredient of marijuana and produces various psychoactive effects through the brain cannabinoid (cb1) receptor. |
2001-05-17 |
2023-08-12 |
rat |
| M J Reid, L M Bornhei. Cannabinoid-induced alterations in brain disposition of drugs of abuse. Biochemical pharmacology. vol 61. issue 11. 2001-05-10. PMID:11331071. |
because marijuana is often consumed with other drugs, the influence of cannabinoids on the brain levels of several other drugs of abuse was also determined. |
2001-05-10 |
2023-08-12 |
mouse |
| M J Reid, L M Bornhei. Cannabinoid-induced alterations in brain disposition of drugs of abuse. Biochemical pharmacology. vol 61. issue 11. 2001-05-10. PMID:11331071. |
these findings demonstrate that cannabinoids can increase the brain concentrations and pharmacological actions of several other drugs of abuse, thereby providing a biochemical basis for the common practice of using marijuana concurrently with such drugs. |
2001-05-10 |
2023-08-12 |
mouse |
| M Fellermeier, W Eisenreich, A Bacher, M H Zen. Biosynthesis of cannabinoids. Incorporation experiments with (13)C-labeled glucoses. European journal of biochemistry. vol 268. issue 6. 2001-05-03. PMID:11248677. |
the biosynthesis of cannabinoids was studied in cut sprouts of cannabis sativa by incorporation experiments using mixtures of unlabeled glucose and [1-(13)c]glucose or [u-(13)c(6)]glucose. |
2001-05-03 |
2023-08-12 |
Not clear |
| E M Williamson, F J Evan. Cannabinoids in clinical practice. Drugs. vol 60. issue 6. 2001-04-12. PMID:11152013. |
the most important natural cannabinoid is the psychoactive tetrahydrocannabinol (delta9-thc); others include cannabidiol (cbd) and cannabigerol (cbg). |
2001-04-12 |
2023-08-12 |
Not clear |
| E M Williamson, F J Evan. Cannabinoids in clinical practice. Drugs. vol 60. issue 6. 2001-04-12. PMID:11152013. |
cannabis is frequently used by patients with multiple sclerosis (ms) for muscle spasm and pain, and in an experimental model of ms low doses of cannabinoids alleviated tremor. |
2001-04-12 |
2023-08-12 |
Not clear |
| E M Williamson, F J Evan. Cannabinoids in clinical practice. Drugs. vol 60. issue 6. 2001-04-12. PMID:11152013. |
the relatively slow elimination from the body of the cannabinoids has safety implications for cognitive tasks, especially driving and operating machinery; although driving impairment with cannabis is only moderate, there is a significant interaction with alcohol. |
2001-04-12 |
2023-08-12 |
Not clear |
| P Lorenzo Fernánde. [Potential therapeutic usefulness of cannabis and cannabinoids]. Anales de la Real Academia Nacional de Medicina. vol 117. issue 3. 2001-04-12. PMID:11205042. |
[potential therapeutic usefulness of cannabis and cannabinoids]. |
2001-04-12 |
2023-08-12 |
Not clear |
| P Lorenzo Fernánde. [Potential therapeutic usefulness of cannabis and cannabinoids]. Anales de la Real Academia Nacional de Medicina. vol 117. issue 3. 2001-04-12. PMID:11205042. |
diseases in which cannabis and cannabinoids have demonstrated some medicinal putative properties are: nausea and vomiting associated with cancer chemotherapy, muscle spasticity (multiple sclerosis, movement disorders), pain, anorexia, epilepsy, glaucoma, bronchial asthma, neuroegenerative diseases, cancer, etc. |
2001-04-12 |
2023-08-12 |
Not clear |
| M Guzmán, I Galve-Roperh, C Sánche. Ceramide: a new second messenger of cannabinoid action. Trends in pharmacological sciences. vol 22. issue 1. 2001-03-29. PMID:11165667. |
cannabinoids, the active components of cannabis sativa (marijuana), and their endogenous counterparts exert their effects by binding to specific g(i/o)-protein-coupled receptors that modulate adenylyl cyclase, ion channels and extracellular signal-regulated kinases. |
2001-03-29 |
2023-08-12 |
Not clear |
| A F Hoffman, C R Lupic. Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids. Journal of neurophysiology. vol 85. issue 1. 2001-02-15. PMID:11152707. |
taken together, these data suggest that cannabinoids and opioids differentially modulate inhibitory and excitatory synaptic transmission in the nac and that the abuse liability of marijuana may be related to the direct actions of cannabinoids in this structure. |
2001-02-15 |
2023-08-12 |
rat |
| G Kunos, Z Járai, S Bátkai, S K Goparaju, E J Ishac, J Liu, L Wang, J A Wagne. Endocannabinoids as cardiovascular modulators. Chemistry and physics of lipids. vol 108. issue 1-2. 2001-01-11. PMID:11106789. |
cannabinoids, the bioactive constituents of the marijuana plant and their synthetic and endogenous analogs cause not only neurobehavioral, but also cardiovascular effects. |
2001-01-11 |
2023-08-12 |
Not clear |
| L De Petrocellis, D Melck, T Bisogno, V Di Marz. Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders. Chemistry and physics of lipids. vol 108. issue 1-2. 2001-01-11. PMID:11106791. |
the long history of the medicinal use of cannabis sativa and, more recently, of its chemical constituents, the cannabinoids, suggests that also the endogenous ligands of cannabinoid receptors, the endocannabinoids, and, particularly, their derivatives may be used as therapeutic agents. |
2001-01-11 |
2023-08-12 |
Not clear |
| S O Jacobsson, E Rongård, M Stridh, G Tiger, C J Fowle. Serum-dependent effects of tamoxifen and cannabinoids upon C6 glioma cell viability. Biochemical pharmacology. vol 60. issue 12. 2001-01-11. PMID:11108795. |
in the present study, the effects of the combination of tamoxifen ((z)-2[p-(1,2-diphenyl-1-butenyl)phenoxy]-n,n-dimethylamine citrate) and three cannabinoids (delta(9)-tetrahydrocannabinol [delta(9)-thc], cannabidiol, and anandamide [aea]) upon the viability of c6 rat glioma cells was assessed at different incubation times and using different culturing concentrations of foetal bovine serum (fbs). |
2001-01-11 |
2023-08-12 |
human |