| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shunaha Kim-Fine, Jamie Greenfield, Kathleen H Chaput, Magali Robert, Luanne M Met. Cannabinoids and bladder symptoms in multiple sclerosis. Multiple sclerosis and related disorders. vol 54. 2021-10-05. PMID:34216995. |
while there are data that support a biological mechanism by which cannabinoids can impact various other symptoms of ms, the evidence of effectiveness of cannabis as a treatment for bladder symptoms remains unsettled. |
2021-10-05 |
2023-08-13 |
Not clear |
| Miriam Stempfer, Vera Reinstadler, Anna Lang, Herbert Oberache. Analysis of cannabis seizures by non-targeted liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis. vol 205. 2021-10-05. PMID:34474231. |
due to the popularity of recreational cannabis use, contamination of this drug with diverse classes of chemicals, including pesticides, mycotoxins, and synthetic cannabinoids, has been identified as major threat for public health. |
2021-10-05 |
2023-08-13 |
Not clear |
| Jessica Nixon, Hanan Abramovici, Ashley Cabecinha, Camilo Martinez-Farina, Joseph Hui, Lee Elli. Assessing the bioactivity of cannabis extracts in larval zebrafish. Journal of cannabis research. vol 3. issue 1. 2021-10-05. PMID:34598738. |
whole-plant cannabis extracts are consumed by the public for medical and non-medical ("recreational") purposes but are poorly researched compared to pure cannabinoids. |
2021-10-05 |
2023-08-13 |
zebrafish |
| Jessica Nixon, Hanan Abramovici, Ashley Cabecinha, Camilo Martinez-Farina, Joseph Hui, Lee Elli. Assessing the bioactivity of cannabis extracts in larval zebrafish. Journal of cannabis research. vol 3. issue 1. 2021-10-05. PMID:34598738. |
there is emerging evidence that cannabis extracts comprising complex mixtures of cannabinoids may have different biological effects from that of pure cannabinoids. |
2021-10-05 |
2023-08-13 |
zebrafish |
| Amir Fruman, Refael Stryjer, Shira Weizman, Assaf Shele. Creatine kinase levels in psychotic patients who use cannabinoids. International clinical psychopharmacology. vol 36. issue 1. 2021-10-04. PMID:33165025. |
higher rate of elevated creatine kinase levels was observed in hospitalized psychotic cannabinoid users, possibly due to a cannabis activity at peripheral or brain tissues. |
2021-10-04 |
2023-08-13 |
Not clear |
| Isabel González-Mariscal, Beatriz Carmona-Hidalgo, Matthias Winkler, Juan D Unciti-Broceta, Alejandro Escamilla, María Gómez-Cañas, Javier Fernández-Ruiz, Bernd L Fiebich, Silvana-Yanina Romero-Zerbo, Francisco J Bermúdez-Silva, Juan A Collado, Eduardo Muño. (+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB Pharmacological research. vol 169. 2021-10-04. PMID:34019978. |
(+)-trans-cannabidiol-2-hydroxy pentyl is a dual cb natural cannabidiol ((-)-cbd) and its derivatives have increased interest for medicinal applications due to their broad biological activity spectrum, including targeting of the cannabinoid receptors type 1 (cb |
2021-10-04 |
2023-08-13 |
Not clear |
| Liesl Janssens, Annelies Cannaert, Matthew J Connolly, Huiling Liu, Christophe P Stov. In vitro activity profiling of Cumyl-PEGACLONE variants at the CB Drug testing and analysis. vol 12. issue 9. 2021-10-01. PMID:32490586. |
scras are known to typically exert higher cannabinoid activity than tetrahydrocannabinol from cannabis, thereby entailing a greater health risk. |
2021-10-01 |
2023-08-13 |
Not clear |
| Chiung-Wei Huang, Pi-Chen Lin, Jian-Lin Chen, Ming-Jen Le. Cannabidiol Selectively Binds to the Voltage-Gated Sodium Channel Na Biomedicines. vol 9. issue 9. 2021-10-01. PMID:34572327. |
cannabidiol selectively binds to the voltage-gated sodium channel na cannabidiol (cbd), one of the cannabinoids from the cannabis plant, can relieve the myotonia resulting from sodium channelopathy, which manifests as repetitive discharges of muscle membrane. |
2021-10-01 |
2023-08-13 |
Not clear |
| Julie Schjødtz Hansen, Rikke Middelhede Hansen, Thor Petersen, Stefan Gustavsen, Annette Bang Oturai, Finn Sellebjerg, Eva Aggerholm Sædder, Helge Kasch, Peter Vestergaard Rasmussen, Nanna Brix Finnerup, Kristina Bacher Svendse. The Effect of Cannabis-Based Medicine on Neuropathic Pain and Spasticity in Patients with Multiple Sclerosis and Spinal Cord Injury: Study Protocol of a National Multicenter Double-Blinded, Placebo-Controlled Trial. Brain sciences. vol 11. issue 9. 2021-10-01. PMID:34573231. |
however, knowledge about effects, side effects, choice of active cannabinoids (Δ9-tetrahydrocannabinol (thc), cannabidiol (cbd) alone or in combination), and doses of cbm remains limited. |
2021-10-01 |
2023-08-13 |
Not clear |
| Martina Rabino, Sara Mallia, Elisa Castiglioni, Davide Rovina, Giulio Pompilio, Aoife Gowra. The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577636. |
the endocannabinoid system and cannabidiol: past, present, and prospective for cardiovascular diseases. |
2021-10-01 |
2023-08-13 |
Not clear |
| Martina Rabino, Sara Mallia, Elisa Castiglioni, Davide Rovina, Giulio Pompilio, Aoife Gowra. The Endocannabinoid System and Cannabidiol: Past, Present, and Prospective for Cardiovascular Diseases. Pharmaceuticals (Basel, Switzerland). vol 14. issue 9. 2021-10-01. PMID:34577636. |
this review, following a general overview of cannabis and the endocannabinoid system, assiduously describes its role within the context of cardiovascular diseases, paying particular attention to the janus influence that endocannabinoid system modulators can have on the cardiovascular system. |
2021-10-01 |
2023-08-13 |
Not clear |
| Hajra Khurshid, Israa A Qureshi, Nasrin Jahan, Terry R Went, Waleed Sultan, Alisha Sapkota, Michael Alfons. A Systematic Review of Fibromyalgia and Recent Advancements in Treatment: Is Medicinal Cannabis a New Hope? Cureus. vol 13. issue 8. 2021-09-29. PMID:34567876. |
we followed preferred reporting items for systematic review and meta-analysis (prisma) guidelines in searching pubmed, medline (through pubmed), pubmed central, and google scholar using keywords "fibromyalgia, chronic pain, cannabis, cannabinoids, pharmacotherapy, alternative therapy" and medical subject heading (mesh) words. |
2021-09-29 |
2023-08-13 |
human |
| Hajra Khurshid, Israa A Qureshi, Nasrin Jahan, Terry R Went, Waleed Sultan, Alisha Sapkota, Michael Alfons. A Systematic Review of Fibromyalgia and Recent Advancements in Treatment: Is Medicinal Cannabis a New Hope? Cureus. vol 13. issue 8. 2021-09-29. PMID:34567876. |
the two main compounds of cannabis with analgesic and anti-inflammatory properties are cannabidiol (cbd) and delta-9-tetrahydrocannabinol (thc), and their ratio determines the effect on various symptoms of fms. we included studies regarding the use of cannabinoids in the treatment of fibromyalgia, investigating the use of nabilone, dronabinol (a synthetic analog of thc), bedrocan (22.4 mg thc, <1 mg cbd), bediol (13.4 mg thc, 17.8 mg cbd), and bedrolite (18.4 mg cbd, <1 mg thc). |
2021-09-29 |
2023-08-13 |
human |
| Grace Blest-Hopley, Aisling O'Neill, Robin Wilson, Vincent Giampietro, David Lythgoe, Alice Egerton, Sagnik Bhattacharyy. Adolescent-onset heavy cannabis use associated with significantly reduced glial but not neuronal markers and glutamate levels in the hippocampus. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31478302. |
we investigated the effect of persistent cannabis use on the brain levels of n-acetyl aspartate (naa) and myoinositol, the metabolite markers of neurons and glia, the site of the main central cannabinoid cb1 receptor, and the levels of glutamate, the neurotransmitter directly affected by cb1 modulation. |
2021-09-28 |
2023-08-13 |
human |
| Grace Blest-Hopley, Aisling O'Neill, Robin Wilson, Vincent Giampietro, David Lythgoe, Alice Egerton, Sagnik Bhattacharyy. Adolescent-onset heavy cannabis use associated with significantly reduced glial but not neuronal markers and glutamate levels in the hippocampus. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31478302. |
we investigated cannabis users (cus) who started using during adolescence, the period of greatest vulnerability to cannabis effects and focused on the hippocampus, where type 1 cannabinoid receptors (cbr1) are expressed in high density and have been linked to altered glutamatergic neurotransmission. |
2021-09-28 |
2023-08-13 |
human |
| Julia Sweigert, Kathleen Pagulayan, Gabriella Greco, Matthew Blake, Mary Larimer, Natalia M Kleinhan. A multimodal investigation of cerebellar integrity associated with high-risk cannabis use. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31814242. |
recent evidence increasingly points to the role of the cerebellum in various nonmotor networks, and the cerebellum's expression of cannabinoid receptors may pose particular vulnerabilities to the consequences of cannabis use. |
2021-09-28 |
2023-08-13 |
Not clear |
| b' Pietro Brunetti, Alfredo Fabrizio Lo Faro, Filippo Pirani, Paolo Berretta, Roberta Pacifici, Simona Pichini, Francesco Paolo Busard\\xc3\\xb. Pharmacology and legal status of cannabidiol. Annali dell\'Istituto superiore di sanita. vol 56. issue 3. 2021-09-27. PMID:32959794.' |
cannabidiol (cbd) is the second most abundant cannabinoid present in cannabis sativa l. it is not associated with psychotropic activity and is capable to mitigate the psychotomimetic effects produced by tetrahydrocannabinol (thc). |
2021-09-27 |
2023-08-13 |
Not clear |
| Itziar Bonilla-Del Río, Nagore Puente, Amaia Mimenza, Almudena Ramos, Maitane Serrano, Leire Lekunberri, Inmaculada Gerrikagoitia, Brian R Christie, Patrick C Nahirney, Pedro Grande. Acute Δ9-tetrahydrocannabinol prompts rapid changes in cannabinoid CB The Journal of comparative neurology. vol 529. issue 9. 2021-09-23. PMID:33368252. |
acute Δ9-tetrahydrocannabinol prompts rapid changes in cannabinoid cb the use and abuse of cannabis can be associated with significant pathophysiology, however, it remains unclear whether (1) acute administration of Δ-9-tetrahydrocannabinol (thc) during early adulthood alters the cannabinoid type 1 (cb |
2021-09-23 |
2023-08-13 |
Not clear |
| Shane Darke, Samuel Banister, Michael Farrell, Johan Duflou, Julia Lappi. 'Synthetic cannabis': A dangerous misnomer. The International journal on drug policy. vol 98. 2021-09-23. PMID:34343944. |
rather, the substances referred to as 'synthetic cannabis' in public discourse should instead be referred to consistently as synthetic cannabinoid receptor agonists (scras), a drug class distinct from plant-derived cannabinoids. |
2021-09-23 |
2023-08-13 |
Not clear |
| Giorgia Galiazzo, Margherita De Silva, Fiorella Giancola, Riccardo Rinnovati, Angelo Peli, Roberto Chiocchett. Cellular distribution of cannabinoid-related receptors TRPV1, PPAR-gamma, GPR55 and GPR3 in the equine cervical dorsal root ganglia. Equine veterinary journal. 2021-09-23. PMID:34418142. |
of the cannabinoids contained in cannabis sativa, cannabidiol (cbd) does not produce psychotropic effects and seems to represent a molecule having great therapeutic potential. |
2021-09-23 |
2023-08-13 |
Not clear |