| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yifei Shen, Jie Liu, Bingyi Yao, Yuanjin Zhang, Shengbo Huang, Chenmeizi Liang, Junze Huang, Yu Tang, Xin Wan. Non-alcoholic fatty liver disease changes the expression and activity of hepatic drug-metabolizing enzymes and transporters in rats. Toxicology letters. 2024-04-25. PMID:38663832. |
in this study, a nafld rat model was constructed by feeding rats with methionine and choline deficiency diets for 6 weeks, and the mrna and protein levels of drug-metabolizing enzymes and transporter were analyzed by real-time fluorescent quantitative pcr and western blot, respectively. |
2024-04-25 |
2024-04-28 |
rat |
| Fábio Soares de Lima, Manoel Francisco Sá Filho, Leandro Ferreira Greco, José Eduardo Portela Santo. Rumen-Protected Choline Improves Metabolism and Lactation Performance in Dairy Cows. Animals : an open access journal from MDPI. vol 14. issue 7. 2024-04-13. PMID:38612255. |
the objectives of this study were to determine the effects of feeding rumen-protected choline (rpc) on lactation and metabolism in dairy cows. |
2024-04-13 |
2024-04-15 |
Not clear |
| Usman Arshad, Roney Zimpel, Ali Husnain, Michael B Poindexter, José E P Santo. Effect of rumen-protected choline on fat digestibility and lymph metabolome in dairy cows. Journal of animal physiology and animal nutrition. 2024-02-21. PMID:38379267. |
feeding rpc increased the concentration of choline and affected the concentrations of analytes involved in metabolic pathways associated with amino acid metabolism and biosynthesis of phospholipids in lymph compared with con. |
2024-02-21 |
2024-02-23 |
Not clear |
| Shihui Mei, Guangxia He, Tiantian Zhang, Ze Chen, Rong Zhang, Yixiao Liao, Mingming Zhu, Duhan Xu, Yanjuan Shen, Bijun Zhou, Kaigong Wang, Chunmei Wang, Chao Chen, Erpeng Zhu, Zhentao Chen. Effect of feeding fermented distiller's grains diets on immune status and metabolomics of spleen and mesenteric lymph nodes in finishing cattle. Journal of proteomics. 2024-02-07. PMID:38325729. |
these results suggest that feeding fdg may promote spleen development by regulating choline metabolism, glycerophospholipid metabolism, unsaturated fatty acid biosynthesis and insulin resistance metabolic pathways without affecting immune indexes, and may affect mln development by regulating choline metabolism in cancer. |
2024-02-07 |
2024-02-10 |
cattle |
| Shihui Mei, Guangxia He, Tiantian Zhang, Ze Chen, Rong Zhang, Yixiao Liao, Mingming Zhu, Duhan Xu, Yanjuan Shen, Bijun Zhou, Kaigong Wang, Chunmei Wang, Chao Chen, Erpeng Zhu, Zhentao Chen. Effect of feeding fermented distiller's grains diets on immune status and metabolomics of spleen and mesenteric lymph nodes in finishing cattle. Journal of proteomics. 2024-02-07. PMID:38325729. |
in this study, we found that feeding fdg may promote spleen development by regulating choline metabolism in cancer, glycerophospholipid metabolism, biosynthesis of unsaturated fatty acids and insulin resistance metabolic pathways, and may affect mln development by regulating choline metabolism in cancer. |
2024-02-07 |
2024-02-10 |
cattle |
| Holger Marten. [The lipidosis in the liver of the dairy cow: Part 2 Genetic predisposition and prophylaxis]. Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere. vol 51. issue 5. 2023-11-13. PMID:37956673. |
they consist of feeding a glucogenic diet, restricted feeding during the close-up time as well as supplementation with choline, niacin, carnitine, or the reduction of milking frequency. |
2023-11-13 |
2023-11-20 |
Not clear |
| Jingjing Lu, Xinyue Tao, Jiaxiang Luo, Tingting Zhu, Lefei Jiao, Peng Sun, Qicun Zhou, Douglas R Tocher, Min Ji. Dietary choline activates the Ampk/Srebp signaling pathway and decreases lipid levels in Pacific white shrimp ( Animal nutrition (Zhongguo xu mu shou yi xue hui). vol 15. 2023-10-11. PMID:37818178. |
dietary choline activates the ampk/srebp signaling pathway and decreases lipid levels in pacific white shrimp ( an 8-week feeding trial was conducted in pacific white shrimp ( |
2023-10-11 |
2023-10-15 |
Not clear |
| Usman Arshad, Marcos G Zenobi, Paula Tribulo, Charles R Staples, José E P Santo. Dose-dependent effects of rumen-protected choline on hepatic metabolism during induction of fatty liver in dry pregnant dairy cows. PloS one. vol 18. issue 10. 2023-10-05. PMID:37796906. |
feeding rpc during feed restriction increased abundance of transcripts involved in choline metabolism (chka, pld1), synthesis of apolipoprotein-b100 (apob100), and antioxidant activity (gpx3), and decreased the abundance of transcripts involved in hepatic lipogenesis (dgat2, srebf1) and acute phase response (saa3). |
2023-10-05 |
2023-10-07 |
Not clear |
| Ulf Kulik, Caroline Moesta, Reinhard Spanel, Jürgen Borla. Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary non-function of fatty liver allografts. Translational research : the journal of laboratory and clinical medicine. 2023-09-18. PMID:37722450. |
in an effort to investigate mechanism of fatty-allograft associated pnfs, we induced fatty liver disease in donor animals by feeding rats a diet deficient in methionine and choline (mcd). |
2023-09-18 |
2023-10-07 |
rat |
| Brianna N Tate, Gary P Van Guilder, Marwa Aly, Lisa A Spence, M Elena Diaz-Rubio, Henry H Le, Elizabeth L Johnson, Joseph W McFadden, Cydne A Perr. Changes in Choline Metabolites and Ceramides in Response to a DASH-Style Diet in Older Adults. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686719. |
this feeding trial evaluated the impact of the dietary approaches to stop hypertension diet on changes in plasma choline, choline metabolites, and ceramides in obese older adults; 28 adults consumed 3oz (n = 15) or 6oz (n = 13) of beef within a standardized dash diet for 12 weeks. |
2023-09-09 |
2023-10-07 |
Not clear |
| U Arshad, A Husnain, M B Poindexter, R Zimpel, C D Nelson, J E P Santo. Rumen-protected choline reduces hepatic lipidosis by increasing hepatic triacylglycerol-rich lipoprotein secretion in dairy cows. Journal of dairy science. 2023-08-29. PMID:37641262. |
feeding 25.8 g/d of choline ion as rpc mediated increased hepatic triacylglycerol secretion to promote lipotropic effects that reduced hepatic lipidosis in dairy cows. |
2023-08-29 |
2023-09-07 |
Not clear |
| H T Holdorf, W E Brown, G J Combs, S J Henisz, S J Kendall, M J Caputo, K E Ruh, H M Whit. Increasing the prepartum dose of rumen-protected choline: Effects of maternal choline supplementation on growth, feed efficiency, and metabolism in Holstein and Holstein × Angus calves. Journal of dairy science. 2023-07-27. PMID:37500446. |
feeding pregnant cows rumen-protected choline (rpc) may have the potential to affect the growth and health of offspring, but little is known about the optimal dose, or the potential mechanisms of action. |
2023-07-27 |
2023-08-14 |
Not clear |
| William E Brown, Henry T Holdorf, Sara J Johnson, Sophia J Kendall, Sophia E Green, Heather M Whit. In utero choline exposure alters growth, metabolism, feed efficiency, and carcass characteristics of Holstein x Angus cattle from weaning to slaughter. Journal of animal science. 2023-06-12. PMID:37305985. |
feeding rumen protected choline (rpc) to late gestation dairy cows has potential to affect growth in offspring. |
2023-06-12 |
2023-08-14 |
cattle |
| Daphne Siciliani, Trond M Kortner, Gerd M Berge, Anne Kristine Hansen, Åshild Krogdah. Effects of dietary lipid level and environmental temperature on lipid metabolism in the intestine and liver, and choline requirement in Atlantic salmon ( Journal of nutritional science. vol 12. 2023-05-30. PMID:37252685. |
after 8 weeks of feeding, samples of blood, tissue and gut content from six fish per tank were collected, for analyses of histomorphological, biochemical and molecular biomarkers of steatosis and choline requirement. |
2023-05-30 |
2023-08-14 |
Not clear |
| S B Potts, K M Brady, C M Scholte, K M Moyes, N E Sunny, R A Erdma. Rumen-protected choline and methionine during the periparturient period affect choline metabolites, amino acids, and hepatic expression of genes associated with one-carbon and lipid metabolism. Journal of dairy science. 2023-05-12. PMID:37173256. |
feeding supplemental choline and met during the periparturient period can have positive effects on cow performance; however, the mechanisms by which these nutrients affect performance and metabolism are unclear. |
2023-05-12 |
2023-08-14 |
Not clear |
| Hunter W Korsmo, Isma'il Kadam, Aziza Reaz, Rachel Bretter, Anjana Saxena, Caroline H Johnson, Jorge Matias Caviglia, Xinyin Jian. Prenatal Choline Supplement in a Maternal Obesity Model Modulates Offspring Hepatic Lipidomes. Nutrients. vol 15. issue 4. 2023-02-25. PMID:36839327. |
here, we investigated under high-fat (hf) obesogenic feeding how maternal choline supplementation (cs) influenced the hepatic lipidome of mouse offspring. |
2023-02-25 |
2023-08-14 |
mouse |
| Kristen L James, Erik R Gertz, Catherine P Kirschke, Hooman Allayee, Liping Huang, Mary E Kable, John W Newman, Charles B Stephensen, Brian J Bennet. Trimethylamine N-Oxide Response to a Mixed Macronutrient Tolerance Test in a Cohort of Healthy United States Adults. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36768394. |
plasma trimethylamine n-oxide (tmao) concentration increases in responses to feeding tmao, choline, phosphatidylcholine, l-carnitine, and betaine but it is unknown whether concentrations change following a mixed macronutrient tolerance test (mmtt) with limited amounts of tmao precursors. |
2023-02-11 |
2023-08-14 |
Not clear |
| Tanya L France, William A Myers, Awais Javaid, Ian R Frost, Joseph W McFadde. Changes in plasma and milk choline metabolite concentrations in response to the provision of various rumen-protected choline prototypes in lactating dairy cows. Journal of dairy science. 2022-10-14. PMID:36241441. |
choline feeding in the form of rumen-protected choline (rpc) has been shown to increase milk production and improve measures of metabolic health (e.g., liver triglyceride) in dairy cows. |
2022-10-14 |
2023-08-14 |
Not clear |
| Hannah Godfrey, Alexandra Rankovic, Caitlin E Grant, Anna Kate Shoveller, Marica Bakovic, Sarah K Abood, Adronie Verbruggh. Dietary choline in gonadectomized kittens improved food intake and body composition but not satiety, serum lipids, or energy expenditure. PloS one. vol 17. issue 3. 2022-03-17. PMID:35298484. |
dietary choline in gonadectomized kittens improved food intake and body composition but not satiety, serum lipids, or energy expenditure. |
2022-03-17 |
2023-08-13 |
Not clear |
| Wolfgang Bernhard, Marco Raith, Anna Shunova, Stephan Lorenz, Katrin Böckmann, Michaela Minarski, Christian F Poets, Axel R Fran. Choline Kinetics in Neonatal Liver, Brain and Lung-Lessons from a Rodent Model for Neonatal Care. Nutrients. vol 14. issue 3. 2022-03-12. PMID:35277079. |
a major fraction of choline is converted to betaine, feeding the one-carbon pool and this must be taken into account when calculating choline requirements. |
2022-03-12 |
2023-08-13 |
rat |