Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
André Q C Miguel, Ayana Jordan, Brian D Kiluk, Charla Nich, Theresa A Babuscio, Jair J Mari, Kathleen M Carrol. Sociodemographic and clinical outcome differences among individuals seeking treatment for cocaine use disorders. The intersection of gender and race. Journal of substance abuse treatment. vol 106. 2020-09-04. PMID:31540613. |
most published treatment trials for cocaine use disorders (cud) have been conducted with samples composed predominantly of white men and underrepresent women and racial/ethnic minorities. |
2020-09-04 |
2023-08-13 |
Not clear |
Elise E DeVito, Kathleen M Carroll, Theresa Babuscio, Charla Nich, Mehmet Sofuogl. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal of substance abuse treatment. vol 107. 2020-08-31. PMID:31757262. |
no pharmacotherapies are approved for the treatment of cocaine use disorder (cud). |
2020-08-31 |
2023-08-13 |
Not clear |
Elise E DeVito, Kathleen M Carroll, Theresa Babuscio, Charla Nich, Mehmet Sofuogl. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal of substance abuse treatment. vol 107. 2020-08-31. PMID:31757262. |
galantamine, a cholinesterase inhibitor, has shown initial promise for cocaine use reduction in methadone-maintained individuals with cud and cognitive improvement in abstinent individuals with past cud. |
2020-08-31 |
2023-08-13 |
Not clear |
Elise E DeVito, Kathleen M Carroll, Theresa Babuscio, Charla Nich, Mehmet Sofuogl. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal of substance abuse treatment. vol 107. 2020-08-31. PMID:31757262. |
the goal of this 13-week, double-blind, placebo-controlled, randomized controlled trial was to test the efficacy of galantamine (8 mg or 16 mg/day; extended release (er)) for reducing cocaine use and improving cognitive function in individuals with cocaine use disorder (cud). |
2020-08-31 |
2023-08-13 |
Not clear |
Elise E DeVito, Kathleen M Carroll, Theresa Babuscio, Charla Nich, Mehmet Sofuogl. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal of substance abuse treatment. vol 107. 2020-08-31. PMID:31757262. |
these findings did not provide support for the efficacy of galantamine as a treatment for cocaine use in this sample of individuals with cud. |
2020-08-31 |
2023-08-13 |
Not clear |
Thiago Wendt Viola, Jaqueline Bohrer Schuch, Diego Luiz Rovaris, Rafael Genovese, Lucca Tondo, Breno Sanvicente-Vieira, Aline Zaparte, Renata Basso Cupertino, Bruna Santos da Silva, Claiton Henrique Dotto Bau, Rodrigo Grassi-Oliveir. Association between cognitive performance and SYT1-rs2251214 among women with cocaine use disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 12. 2020-08-17. PMID:31562556. |
the snp rs2251214 of the syt1 gene was recently associated with externalizing phenotypes, including adhd and cocaine use disorder (cud). |
2020-08-17 |
2023-08-13 |
Not clear |
Benjamin W Van Tassell, Peter Westman, Cory Trankle, Sade Johns, Dinesh Kadariya, Leo Buckley, Salvatore Carbone, Antonio Abbate, Frederick Gerard Moelle. Noninvasive Hemodynamic Monitoring of Cocaine-Induced Changes in Cardiac Output and Systemic Vascular Resistance in Subjects With Chronic Cocaine Use Disorder. Journal of cardiovascular pharmacology. vol 74. issue 6. 2020-07-27. PMID:31809403. |
cocaine use disorder (cud) is a common problem in the united states and worldwide. |
2020-07-27 |
2023-08-13 |
human |
Benjamin W Van Tassell, Peter Westman, Cory Trankle, Sade Johns, Dinesh Kadariya, Leo Buckley, Salvatore Carbone, Antonio Abbate, Frederick Gerard Moelle. Noninvasive Hemodynamic Monitoring of Cocaine-Induced Changes in Cardiac Output and Systemic Vascular Resistance in Subjects With Chronic Cocaine Use Disorder. Journal of cardiovascular pharmacology. vol 74. issue 6. 2020-07-27. PMID:31809403. |
subjects with chronic cud represent a special population that has experienced long-term cocaine exposure, often without showing signs of cardiovascular disease. |
2020-07-27 |
2023-08-13 |
human |
Benjamin W Van Tassell, Peter Westman, Cory Trankle, Sade Johns, Dinesh Kadariya, Leo Buckley, Salvatore Carbone, Antonio Abbate, Frederick Gerard Moelle. Noninvasive Hemodynamic Monitoring of Cocaine-Induced Changes in Cardiac Output and Systemic Vascular Resistance in Subjects With Chronic Cocaine Use Disorder. Journal of cardiovascular pharmacology. vol 74. issue 6. 2020-07-27. PMID:31809403. |
we herein present prospectively collected data on the acute hemodynamic effects of intravenous cocaine in a cohort of nontreatment-seeking individuals with cud without cardiovascular disease. |
2020-07-27 |
2023-08-13 |
human |
Corey R Roos, Charla Nich, Chung Jung Mun, Theresa A Babuscio, Justin Mendonca, André Q C Miguel, Elise E DeVito, Sarah W Yip, Katie Witkiewitz, Kathleen M Carroll, Brian D Kilu. Clinical validation of reduction in cocaine frequency level as an endpoint in clinical trials for cocaine use disorder. Drug and alcohol dependence. vol 205. 2020-07-06. PMID:31677490. |
we conducted a clinical validation of reduction in cocaine frequency level as a non-abstinence endpoint in rcts for cocaine use disorder (cud). |
2020-07-06 |
2023-08-13 |
Not clear |
Thiago Wendt Viola, Bernardo Aguzzoli Heberle, Aline Zaparte, Breno Sanvicente-Vieira, Leonardo Mendes Wainer, Gabriel Rodrigo Fries, Consuelo Walss-Bass, Rodrigo Grassi-Oliveir. Peripheral blood microRNA levels in females with cocaine use disorder. Journal of psychiatric research. vol 114. 2020-06-25. PMID:31026664. |
based on translational and clinical findings, we compared the expression levels of microrna-124 (mir-124), microrna-181 (mir-181), and microrna-212 (mir-212) between a group of females with cocaine use disorder (cud; n = 30) and a group of healthy female controls (hc; n = 20). |
2020-06-25 |
2023-08-13 |
Not clear |
Theresa M Winhusen, Jeff Theobald, Daniel F Lewi. Substance use outcomes in cocaine-dependent tobacco smokers: A mediation analysis exploring the role of sleep disturbance, craving, anxiety, and depression. Journal of substance abuse treatment. vol 96. 2020-05-28. PMID:30466549. |
sleep disturbance may play a role in cocaine use outcomes and, hence, may be a potential therapeutic target for cocaine use disorder (cud). |
2020-05-28 |
2023-08-13 |
Not clear |
Kyle M Kampma. The treatment of cocaine use disorder. Science advances. vol 5. issue 10. 2020-05-21. PMID:31663022. |
psychosocial treatments remain the treatments of choice for cocaine use disorder (cud), with standard approaches including contingency management and cognitive behavioral therapy. |
2020-05-21 |
2023-08-13 |
Not clear |
Jonathan Buchholz, Andrew J Saxo. Medications to treat cocaine use disorders: current options. Current opinion in psychiatry. vol 32. issue 4. 2020-05-20. PMID:31008728. |
despite these concerns, there are no food and drug administration-approved medications for the treatment of cocaine use disorder (cud). |
2020-05-20 |
2023-08-13 |
Not clear |
Christina Gobin, Marek Schwend. The cognitive cost of reducing relapse to cocaine-seeking with mGlu5 allosteric modulators. Psychopharmacology. vol 237. issue 1. 2020-04-10. PMID:31446451. |
cocaine use disorder (cud) remains difficult to treat with no fda-approved medications to reduce relapse. |
2020-04-10 |
2023-08-13 |
Not clear |
Bruna S da Silva, Renata B Cupertino, Jaqueline B Schuch, Djenifer B Kappel, Breno Sanvicente-Vieira, Cibele E Bandeira, Lisia von Diemen, Felix H P Kessler, Eugenio H Grevet, Rodrigo Grassi-Oliveira, Claiton H D Bau, Diego L Rovari. The association between SYT1-rs2251214 and cocaine use disorder further supports its role in psychiatry. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31059723. |
synaptotagmin-1 is an essential regulator of synaptic vesicle exocytosis, and its encoding gene (syt1) is a genome and transcriptome-wide association hit in cognitive performance, personality and cocaine use disorder (cud) studies. |
2020-03-30 |
2023-08-13 |
human |
Bruna S da Silva, Renata B Cupertino, Jaqueline B Schuch, Djenifer B Kappel, Breno Sanvicente-Vieira, Cibele E Bandeira, Lisia von Diemen, Felix H P Kessler, Eugenio H Grevet, Rodrigo Grassi-Oliveira, Claiton H D Bau, Diego L Rovari. The association between SYT1-rs2251214 and cocaine use disorder further supports its role in psychiatry. Progress in neuro-psychopharmacology & biological psychiatry. vol 94. 2020-03-30. PMID:31059723. |
we tested the association between syt1-rs2251214 and cud susceptibility and severity (addiction severity index) in a sample composed by 315 patients addicted to smoked cocaine and 769 non-addicted volunteers. |
2020-03-30 |
2023-08-13 |
human |
Benjamin R Castine, Natalia Albein-Urios, Oscar Lozano-Rojas, Jose M Martinez-Gonzalez, Jakob Hohwy, Antonio Verdejo-Garci. Self-awareness deficits associated with lower treatment motivation in cocaine addiction. The American journal of drug and alcohol abuse. vol 45. issue 1. 2020-03-27. PMID:30183371. |
individuals with cocaine use disorder (cud) often display behaviours that are paradoxically misaligned with their situation. |
2020-03-27 |
2023-08-13 |
Not clear |
Vitria Adisetiyo, Corinne E McGill, William H DeVries, Jens H Jensen, Colleen A Hanlon, Joseph A Helper. Elevated Brain Iron in Cocaine Use Disorder as Indexed by Magnetic Field Correlation Imaging. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 4. issue 6. 2020-02-24. PMID:30581153. |
iron homeostasis is a critical biological process that may be disrupted in cocaine use disorder (cud). |
2020-02-24 |
2023-08-13 |
Not clear |
Breno Sanvicente-Vieira, Diego Luiz Rovaris, Felipe Ornell, Anne Sordi, Leonardo Melo Rothmann, João Paulo Ottolia Niederauer, Jaqueline Bohrer Schuch, Lisia von Diemen, Felix Henrique Paim Kessler, Rodrigo Grassi-Oliveir. Sex-based differences in multidimensional clinical assessments of early-abstinence crack cocaine users. PloS one. vol 14. issue 6. 2020-02-11. PMID:31226126. |
crack cocaine use disorder (cud) has been related to sex differences. |
2020-02-11 |
2023-08-13 |
Not clear |