All Relations between Paroxetine and serotonin
Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
E N Petersen, E Bechgaard, R J Sortwell, L Wetterber. Potent depletion of 5HT from monkey whole blood by a new 5HT uptake inhibitor, paroxetine (FG 7051). European journal of pharmacology. vol 52. issue 1. 1979-02-21. PMID:102515. |
the lowest dose 1 mg/kg caused 30% depletion of 5ht in whole blood with a level of paroxetine in plasma below 2 ng/ml. |
1979-02-21 |
2023-08-11 |
monkey |
E N Petersen, E Bechgaard, R J Sortwell, L Wetterber. Potent depletion of 5HT from monkey whole blood by a new 5HT uptake inhibitor, paroxetine (FG 7051). European journal of pharmacology. vol 52. issue 1. 1979-02-21. PMID:102515. |
the results showed that paroxetine is a strong depletor of 5ht from whole blood of monkeys conceivably because it inhibits 5ht uptake inhibition. |
1979-02-21 |
2023-08-11 |
monkey |
J B Lasse. Influence of the new 5-HT-uptake inhibitor paroxetine on hypermotility in rats produced by p-chloroamphetamine (PCA) and 4,alpha-dimethyl-7-tyramine (H 77/77). Psychopharmacology. vol 57. issue 2. 1978-07-24. PMID:418448. |
two different forms of hypermotility produced by the amphetamine derivatives pca and h 77/77, 5 mg/kg of each, was studied in rats treated s.c. with the new 5-ht uptake inhibitor paroxetine. |
1978-07-24 |
2023-08-11 |
rat |