| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lars Tönges, Eun Hae Kwon, Stephan Kleb. Monogenetic Forms of Parkinson's Disease - Bridging the Gap Between Genetics and Biomarkers. Frontiers in aging neuroscience. vol 14. 2022-03-23. PMID:35317530. |
the therapy of neurodegenerative diseases such as parkinson's disease (pd) is still limited to the treatment of symptoms and primarily aimed at compensating for dopaminergic hypofunction. |
2022-03-23 |
2023-08-13 |
Not clear |
| Luca Magistrelli, Elena Contaldi, Cristoforo Com. The Immune System as a Therapeutic Target for Old and New Drugs in Parkinson's Disease. CNS & neurological disorders drug targets. 2022-03-11. PMID:35272601. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by loss of dopaminergic neurons and intraneuronal accumulation of protein aggregates. |
2022-03-11 |
2023-08-13 |
Not clear |
| Liyan Yao, Peng Li, Qilei Chen, Anxue Hu, Yanping Wu, Baixiang L. Protective effects of endotoxin tolerance on peripheral lipopolysaccharide-induced neuroinflammation and dopaminergic neuronal injury. Immunopharmacology and immunotoxicology. 2022-03-09. PMID:35260024. |
parkinson's disease is a common chronic neurodegenerative disease characterized by massive loss of dopaminergic neurons in the substantia nigra. |
2022-03-09 |
2023-08-13 |
Not clear |
| Shui Yu, Hai-Rong Peng, Yu-Kai Zhang, Yan-Qing Yin, Jia-Wei Zho. Central dopaminergic control of cell proliferation in the colonic epithelium. Neuroscience research. 2022-03-08. PMID:35257836. |
parkinson's disease (pd) is an age-related neurodegenerative disease, mainly characterized by the loss of dopaminergic (da) neurons in the substantia nigra. |
2022-03-08 |
2023-08-13 |
mouse |
| Tzu-Feng Wang, Shih-Ying Wu, Bo-Syong Pan, Sheng-Feng Tsai, Yu-Min Ku. Inhibition of Nigral Microglial Activation Reduces Age-Related Loss of Dopaminergic Neurons and Motor Deficits. Cells. vol 11. issue 3. 2022-02-15. PMID:35159290. |
parkinson's disease (pd) is an age-related neurodegenerative disease caused by a selective loss of dopaminergic (da) neurons in the substantia nigra (sn). |
2022-02-15 |
2023-08-13 |
mouse |
| Emily M Klann, Upuli Dissanayake, Anjela Gurrala, Matthew Farrer, Aparna Wagle Shukla, Adolfo Ramirez-Zamora, Volker Mai, Vinata Vedam-Ma. The Gut-Brain Axis and Its Relation to Parkinson's Disease: A Review. Frontiers in aging neuroscience. vol 13. 2022-01-24. PMID:35069178. |
parkinson's disease is a chronic neurodegenerative disease characterized by the accumulation of misfolded alpha-synuclein protein (lewy bodies) in dopaminergic neurons of the |
2022-01-24 |
2023-08-13 |
Not clear |
| Maximilian Wulf, Katalin Barkovits-Boeddinghaus, Paula Sommer, Karin Schork, Martin Eisenacher, Peter Riederer, Manfred Gerlach, Steffen Kösters, Britta Eggers, Katrin Marcu. Laser Microdissection-Based Protocol for the LC-MS/MS Analysis of the Proteomic Profile of Neuromelanin Granules. Journal of visualized experiments : JoVE. issue 178. 2022-01-03. PMID:34978295. |
although nmgs-containing dopaminergic neurons are preferentially lost in neurodegenerative diseases like parkinson's disease and dementia with lewy bodies, only little is known about the mechanism of nmg formation and the role of nmgs in health and disease. |
2022-01-03 |
2023-08-13 |
human |
| Ivan N Vlasov, Anelya Kh Alieva, Ekaterina V Novosadova, Elena L Arsenyeva, Anna V Rosinskaya, Suzanna A Partevian, Igor A Grivennikov, Maria I Shadrin. Transcriptome Analysis of Induced Pluripotent Stem Cells and Neuronal Progenitor Cells, Derived from Discordant Monozygotic Twins with Parkinson's Disease. Cells. vol 10. issue 12. 2021-12-24. PMID:34943986. |
parkinson's disease (pd) is a widespread severe neurodegenerative disease that is characterized by pronounced deficiency of the dopaminergic system and disruption of the function of other neuromodulator systems. |
2021-12-24 |
2023-08-13 |
Not clear |
| Lan-Hsin Nancy Lee, Chen-Syuan Huang, Hsiang-Hao Chuang, Hsing-Jung Lai, Cheng-Kai Yang, Ya-Chin Yang, Chung-Chin Ku. An electrophysiological perspective on Parkinson's disease: symptomatic pathogenesis and therapeutic approaches. Journal of biomedical science. vol 28. issue 1. 2021-12-10. PMID:34886870. |
parkinson's disease (pd), or paralysis agitans, is a common neurodegenerative disease characterized by dopaminergic deprivation in the basal ganglia because of neuronal loss in the substantia nigra pars compacta. |
2021-12-10 |
2023-08-13 |
Not clear |
| Chao Gu, Yajing Chen, Yan Chen, Chun-Feng Liu, Zengyan Zhu, Mei Wan. Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson's Disease. Frontiers in aging neuroscience. vol 13. 2021-12-07. PMID:34867296. |
parkinson's disease (pd) is one of the prevalent neurodegenerative diseases associated with preferential loss of dopaminergic (da) neurons in the substantia nigra compacta (snc) and accumulation of α-synuclein in da neurons. |
2021-12-07 |
2023-08-13 |
Not clear |
| Ayumi E Pottenger, Mitchell J Bartlett, Scott J Sherman, Torsten Falk, Helena W Morriso. Evaluation of microglia in a rodent model of Parkinson's disease primed with L-DOPA after sub-anesthetic ketamine treatment. Neuroscience letters. vol 765. 2021-12-03. PMID:34536508. |
parkinson's disease (pd) is a neurodegenerative disease caused by the death of dopaminergic neurons in the substantia nigra pars compacta (snpc), characterized by motor dysfunction. |
2021-12-03 |
2023-08-13 |
rat |
| Chitrakshi Pant, Moumita Chakrabarti, Jolly Janette Mendonza, Bogonda Ganganna, Srihari Pabbaraja, Manika Pal Bhadr. ACS chemical neuroscience. vol 12. issue 23. 2021-12-01. PMID:34763419. |
parkinson's disease is a chronic and progressive neurodegenerative disease, induced by slow and progressive death of the dopaminergic (da) neurons from the midbrain region called substantia nigra (snc) leading to difficulty in locomotion. |
2021-12-01 |
2023-08-13 |
Not clear |
| Richard M Meade, Kathryn J C Watt, Robert J Williams, Jody M Maso. A Downsized and Optimised Intracellular Library-Derived Peptide Prevents Alpha-Synuclein Primary Nucleation and Toxicity Without Impacting Upon Lipid Binding. Journal of molecular biology. vol 433. issue 24. 2021-11-30. PMID:34695381. |
misfolding and aggregation of alpha-synuclein (αs) within dopaminergic neurons is a key factor in the development and progression of a group of age-related neurodegenerative diseases, termed synucleinopathies, that include parkinson's disease (pd). |
2021-11-30 |
2023-08-13 |
Not clear |
| Yung-Tsai Chu, Chun-Hwei Tai, Chin-Hsien Lin, Ruey-Meei W. Updates on the Genetics of Parkinson's Disease: Clinical Implications and Future Treatment. Acta neurologica Taiwanica. vol 30(3). 2021-11-30. PMID:34841503. |
parkinson' disease (pd) is a common neurodegenerative disease with the pathological hallmark of alpha-synuclein aggregation within dopaminergic neurons. |
2021-11-30 |
2023-08-13 |
Not clear |
| Hongli Li, Yaru Feng, Ziyu Chen, Xi Jiang, Zhenyu Zhou, Jinfeng Yuan, Fei Li, Yu Zhang, Xingxu Huang, Shengjie Fan, Xiaojun Wu, Cheng Huan. Pepper component 7-ethoxy-4-methylcoumarin, a novel dopamine D2 receptor agonist, ameliorates experimental Parkinson's disease in mice and Caenorhabditis elegans. Pharmacological research. vol 163. 2021-11-18. PMID:33007422. |
parkinson's disease (pd) is a progressive neurodegenerative disease resulting from the degeneration of dopaminergic (daergic) neurons in the substantia nigra pars compacta (snpc) and subsequent deficit of dopamine in the striatum. |
2021-11-18 |
2023-08-13 |
mouse |
| Nauana Somensi, Samantha Cristiane Lopes, Juciano Gasparotto, Rosângela Mayer Gonçalves, Camila Tiefensee-Ribeiro, Daniel Oppermann Peixoto, Pedro Ozorio Brum, Cibele Martins Pinho, Jonathan Paulo Agnes, Lucas Santos, Jade de Oliveira, Fernando Spiller, José Cláudio Fonseca Moreira, Alfeu Zanotto-Filho, Rui Daniel Prediger, Daniel Pens Gelai. Role of toll-like receptor 4 and sex in 6-hydroxydopamine-induced behavioral impairments and neurodegeneration in mice. Neurochemistry international. vol 151. 2021-11-18. PMID:34710535. |
parkinson's disease (pd) is a neurodegenerative disease characterized by progressive loss of the nigrostriatal dopaminergic neurons that are associated with motor alterations and non-motor manifestations (such as depression). |
2021-11-18 |
2023-08-13 |
mouse |
| Matthew D Demmings, Elizabeth C Tennyson, Gillian N Petroff, Heather E Tarnowski-Garner, Sean P Crega. Activating transcription factor-4 promotes neuronal death induced by Parkinson's disease neurotoxins and α-synuclein aggregates. Cell death and differentiation. vol 28. issue 5. 2021-11-17. PMID:33277577. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra resulting in severe and progressive motor impairments. |
2021-11-17 |
2023-08-13 |
mouse |
| Merve Zaim, Ihsan Kara, Aynur Mudurogl. Black carrot anthocyanins exhibit neuroprotective effects against MPP+ induced cell death and cytotoxicity via inhibition of oxidative stress mediated apoptosis. Cytotechnology. vol 73. issue 6. 2021-11-17. PMID:34776632. |
parkinson's disease (pd) is a common chronic neurodegenerative disease induced by the death of dopaminergic neurons. |
2021-11-17 |
2023-08-13 |
Not clear |
| Ruixian Xing, Xuewen Liu, Buxian Tian, Yan Cheng, Longguang L. Neuroprotective effect of Na Drug development research. vol 82. issue 7. 2021-11-15. PMID:33538000. |
neuroprotective effect of na parkinson's disease (pd) is a disabling neurodegenerative disease mainly caused by degeneration of mesencephalic dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2021-11-15 |
2023-08-13 |
Not clear |
| Shenglan Hu, Jieqiong Tan, Lixia Qin, Lingling Lv, Weiqian Yan, Hainan Zhang, BeiSha Tang, Chunyu Wan. Molecular chaperones and Parkinson's disease. Neurobiology of disease. vol 160. 2021-11-15. PMID:34626793. |
parkinson's disease (pd) is a neurodegenerative disease characterized by progressive death of dopaminergic neurons in the substantia nigra and the formation of lewy bodies (lbs). |
2021-11-15 |
2023-08-13 |
Not clear |